scholarly journals Prevalence of Chronic Kidney Diseases in Patients with Diabetes Mellitus in the Middle East: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Abdallah Y Naser ◽  
Hassan Alwafi ◽  
Basil Alotaibi ◽  
Emad Salawati ◽  
Mohammed Samannodi ◽  
...  

Aims. The prevalence of CKD in patients with diabetes mellitus in the Middle East region is unknown. Therefore, we aimed to understand the pooled prevalence of CKD in patients with diabetes mellitus in the Middle East region. Methods. PubMed, Embase, and Cochrane databases were searched for relevant studies up to October 2020. The search strategy was conducted using both keywords and MeSH terms. Randomised controlled trials (RCTs) and observational studies that included patients from all age groups and any study design that reported on the prevalence of CKD in patients with diabetes mellitus were included. The pooled estimate for the prevalence of CKD in patients with diabetes was calculated using random-effect models with 95% confidence intervals (CIs). Results. A total of 489 citations were identified, of which only nine studies matched our inclusion criteria and were included in the meta-analysis. All of the studies used an observational study design covering a total of 59,395 patients with type 2 diabetes mellitus. The pooled estimate of the prevalence of CKD in patients with diabetes mellitus was 28.96% (95% CI: 19.80–38.11). Conclusions. A high prevalence of CKD in patients with diabetes mellitus in the Middle East region was found. Further epidemiological studies are warranted in this area to have a better estimate of the prevalence of CKD among DM in the Middle East region.

2018 ◽  
Vol 118 ◽  
pp. 653-666 ◽  
Author(s):  
Jamal Rahmani ◽  
Solmaz Alipour ◽  
Ali Miri ◽  
Yadolah Fakhri ◽  
Seyed-Mohammad Riahi ◽  
...  

2021 ◽  
pp. 152483802110360
Author(s):  
Mozhgan Moshtagh ◽  
Rana Amiri ◽  
Simin Sharafi ◽  
Morteza Arab-Zozani

Background and Objective: Intimate partner violence (IPV) is a clinical and social problem globally, especially in the Middle East. This study aimed to analyze the prevalence of IPV and its types against women in the Middle East region. Method: PubMed, Scopus, and Web of Science were searched in January 2020. From 1995 to 2020, all studies performed in the Middle East, investigating at least one type of abuse against women and written in English, entered the study. All included studies were appraised using Joanna Briggs Institute Checklist, which was adapted for prevalence studies. The random effect model of meta-analysis was performed using the Mantel–Haenszel method by comprehensive meta-analysis software. Each type of abuse as event rate with 95% CI was calculated for each variable. Heterogeneity was investigated using the I 2 statistic test. Results: Fifty-five studies encompassing 138,692 participants were included in our meta-analysis. The rate of overall abuse was 26.3 ( n = 55, 95% CI: [15.8, 40.5], p = .002). The highest rate of abuse in the included studies was reported for psychological abuse 48.6% ( n = 46, 95% CI: [39.8, 57.5], p = .758). The rate of abuse for physical, economical, sexual, and injury were 28.4% ( n = 53, 95% CI: [22.1, 35.7], p = .0001), 19% ( n = 10, 95% CI: [9.8, 33.7], p = .0001), 18.5% ( n = 45, 95% CI: [13.6, 24.6], p = .0001), and 18.4% ( n = 5, 95% CI: [7.1, 40.2], p = 0.008), respectively. The overall abuse reported by World Health Organization Multi-Country Domestic Violence (DV)Questionnaire was 25.7% ( n = 17, 95% CI: [18.4, 34.7], p = .0001). This value was 41.8% ( n = 11, 95% CI: [29.7, 55], p = .223) for the Conflict Tactics Scale Questionnaire. Conclusion: Although this review highlights the lack of or insufficient IPV data in some contexts and inconsistencies in defining and measuring IPV among studies, the evidence shows that a moderate to high pattern of abuse has been observed in the study population. Due to this region’s unique cultural-religious characteristics, it is urgent to reduce this phenomenon.


Acta Tropica ◽  
2020 ◽  
Vol 202 ◽  
pp. 105241 ◽  
Author(s):  
Abdol-Samad Abedi ◽  
Fataneh Hashempour-Baltork ◽  
Adel Mirza Alizadeh ◽  
Samira Beikzadeh ◽  
Hedayat Hosseini ◽  
...  

2021 ◽  
Author(s):  
Samira Karimaei ◽  
Hamid Reza Tohidinik ◽  
Davoud Afshar ◽  
Mohammad Reza Pourmand ◽  
Soheila Habibi Ghahfarokhi ◽  
...  

This study aimed to explore the prevalence, antimicrobial resistance levels, and serotype distribution of S. pneumoniae in the Middle East region. We conducted a systematic literature review by searching several databases including PubMed, ISI Web of Science, Scopus, Google scholar through 2000 to 2017 by using the following keywords: “Streptococcus pneumoniae”, “pneumococcus”, “serotype”, “Antibiotic resistance,” and “Middle East “in combination with “OR” and “AND” Boolean Operators within Title/Abstract/Keywords fields. We used a random-effects model to calculate the pooled prevalence and 95% confidence intervals (CIs) for binomial variables. All statistical analyses were done using STATA 12.0 (STATA Corp, College Station, TX). We found 73 articles appropriate, on the word of inclusion and exclusion criteria, for inclusion in this systematic review and meta-analysis. The result revealed that the pooled prevalence of S. pneumoniae carriage was 35% (95% CI: 26-44%). The most frequent pneumococcal serotypes were19, 19F, 6, 23 and 6A/B which were found in 19%,12%, 11%, 10% and 10% of isolates respectively. Pneumococcal resistance reported for azithromycin, cefaclor, clarithromycin, chloramphenicol, erythromycin, and tetracycline were 24%, 37%, 23%, 11%, 26%, and 29% respectively, while vancomycin resistance was not reported. The highest resistant prevalence was reported against co-trimoxazole (Trimethoprim/sulfamethoxazole). For this antibiotic, a pooled resistance prevalence of 43% was identified. The present review demonstrates that the prevalence of S. pneumoniae carriage was high in the Middle East region. Surveillance must be continued in this region to evaluate. The resistance pattern and serotype distribution.


2018 ◽  
Vol 192 ◽  
pp. 67-74 ◽  
Author(s):  
Larisa Bešić ◽  
Imer Muhović ◽  
Fatima Mrkulić ◽  
Lemana Spahić ◽  
Ammar Omanović ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Xingyun Zhu ◽  
Lina Zhao ◽  
Jing Chen ◽  
Chu Lin ◽  
Fang Lv ◽  
...  

PurposeThe effect of physical activity on glycemic variability remains controversial. This meta-analysis aimed to assess the overall effect of physical activity treatment on glycemic variability in patients with diabetes.MethodsPubMed/MEDLINE, Embase, and Cochrane databases were searched for clinical trials that conducted in patients with type 1 diabetes mellitus and type 2 diabetes mellitus with reports of the mean amplitude of glycemic excursion (MAGE), time in range (TIR), time above range (TAR), or time below range (TBR). Eligible trials were analyzed by fixed-effect model, random effect model, and meta-regression analysis accordingly.ResultsIn total, thirteen trials were included. Compared with the control group, physical activity intervention was significantly associated with increased TIR (WMDs, 4.17%; 95% CI, 1.11 to 7.23%, P<0.01), decreased MAGE (WMDs, -0.68 mmol/L; 95% CI, -1.01 to -0.36 mmol/L, P<0.01) and decreased TAR (WMDs, -3.54%; 95% CI, -5.21 to -1.88%, P<0.01) in patients with diabetes, but showed insignificant effects on TBR. Patients with higher baseline BMI levels was associated with a greater decrease in MAGE (β=-0.392, 95% CI: -0.710, -0.074), and patients with lower baseline HbA1c levels was associated with a greater increase in TBR during physical activities (β=-0.903, 95% CI: -1.550, -0.255).ConclusionPhysical activity was associated with significantly decreased glycemic variability in patients with diabetes. Patients with higher BMI might benefit more from physical activity therapy in terms of a lower MAGE. Hypoglycemia associated with physical activity treatment still warranted caution, especially in patients with intensive glycemic control.Systematic Review RegistrationPROSPERO [CRD42021259807].


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Gerritje S. Mijnhout ◽  
Boudewijn J. Kollen ◽  
Alaa Alkhalaf ◽  
Nanno Kleefstra ◽  
Henk J. G. Bilo

Objective. We performed a systematic review of the literature to evaluate the effects of alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes mellitus.Research design and methods. The databases MEDLINE and EMBASE were searched using the key words “lipoic acid’’, “thioctic acid’’, “diabet*’’, and the MeSH-terms “thioctic acid’’ and “diabetes mellitus’’. Randomised controlled trials using the TSS score as the outcome measure were selected and assessed for their methodological quality. Study selection and quality assessment were performed independently by three observers.Results. Overall, the pooled standardized mean difference estimated from all trials revealed a reduction in TSS scores of −2.26 (CI: −3.12 to −1.41;P=0.00001) in favour of alpha lipoic acid administration. Subgroup analyses of oral administration (−1.78 CI: −2.45 to −1.10;P=0.00001) and intravenous administration (−2.81 CI: −4.16 to −1.46;P=0.0001) confirmed the robustness of the overall result.Conclusions. When given intravenously at a dosage of 600 mg/day over a period of 3 weeks, alpha lipoic acid leads to a significant and clinically relevant reduction in neuropathic pain (grade of recommendation A). It is unclear if the significant improvements seen after 3–5 weeks of oral administration at a dosage of>600 mg/day are clinically relevant.


2018 ◽  
Vol 11 (1-2) ◽  
pp. 257-278 ◽  
Author(s):  
Shirzad Azad

In spite of her troubled presidency at home and premature, ignominious exit from power, Park Geun-hye made serious attempts to bolster the main direction of the Republic of Korea’s (ROK) foreign policy toward the Middle East. A collaborative drive for accomplishing a new momentous boom was by and large a dominant and recurring theme in the Park government’s overall approach to the region. Park enjoyed both personal motivation as well as politico-economic justifications to push for such arduous yet potentially viable objective. Although the ROK’s yearning for a second boom in the Middle East was not ultimately accomplished under the Park presidency, nonetheless, the very aspiration played a crucial role in either rekindling or initiating policy measures in South Korea’s orientation toward different parts of a greater Middle East region, extending from the Gulf Cooperation Council (GCC) to Morocco.


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