scholarly journals A Narrative Review of Neuroimaging Studies in Acupuncture for Migraine

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Peihong Ma ◽  
Xiaohui Dong ◽  
Yuzhu Qu ◽  
Zhaoxuan He ◽  
Tao Yin ◽  
...  
Keyword(s):  
Complementary Therapy ◽  
Sham Acupuncture ◽  
Biomedical Literature ◽  
Cochrane Library ◽  
Future Research ◽  
Knowledge Infrastructure ◽  
Pain Pathway ◽  
Medial Pain ◽  
Chinese National Knowledge Infrastructure ◽  
Lateral Pain

Acupuncture has been widely used as an alternative and complementary therapy for migraine. With the development of neuroimaging techniques, the central mechanism of acupuncture for migraine has gained increasing attention. This review aimed to analyze the study design and main findings of neuroimaging studies of acupuncture for migraine to provide the reference for future research. The original studies were collected and screened in three English databases (PubMed, Embase, and Cochrane Library) and four Chinese databases (Chinese National Knowledge Infrastructure, Chinese Biomedical Literature database, the Chongqing VIP database, and Wanfang database). As a result, a total of 28 articles were included. Functional magnetic resonance imaging was the most used neuroimaging technique to explore the cerebral activities of acupuncture for migraine. This review manifested that acupuncture could elicit cerebral responses on patients with migraine, different from sham acupuncture. The results indicated that the pain systems, including the medial pain pathway, lateral pain pathway, and descending pain modulatory system, participated in the modulation of the cerebral activities of migraine by acupuncture.

scholarly journals Clinical Effects and Safety of Electroacupuncture for the Treatment of Poststroke Dysphagia: A Comprehensive Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Jinke Huang ◽  
Yao Shi ◽  
Xiaohui Qin ◽  
Min Shen ◽  
Manli Wu ◽  
...  
Keyword(s):  
Rating Scale ◽  
Meta Analysis ◽  
Effective Rate ◽  
Control Treatment ◽  
Sufficient Evidence ◽  
Cochrane Library ◽  
Clinical Effects ◽  
Knowledge Infrastructure ◽  
Swallowing Rehabilitation ◽  
Chinese National Knowledge Infrastructure

Objectives. Electroacupuncture (EA), an extension of acupuncture, which is based on traditional acupuncture combined with modern electrotherapy, is commonly used for poststroke dysphagia (PSD) in clinical treatment and research. However, there is still a lack of sufficient evidence to recommend the routine use of EA for PSD. The aim of this study was to assess the efficacy and safety of EA in the treatment of PSD. Methods. Randomized controlled trials (RCTs) evaluating the effects of EA on PSD were identified through a comprehensive literature search of the PubMed, Embase, Cochrane Library, Web of Science, Chinese National Knowledge Infrastructure, Chinese Biomedical Database, and VIP databases from their inception to July 2020. The quality assessment of the included trials was performed based on the guidance of the Cochrane Reviewers’ Handbook, and meta-analysis (MA) was performed by using the RevMan 5.3 software. Results. Sixteen trials were identified, and these included 1,216 patients with PSD. The results demonstrated that EA in combination with swallowing rehabilitation training (SRT) was significantly superior to SRT alone with regard to effective rate (OR 5.40, 95% CI [3.78, 7.72], P < 0.00001 , water swallow test (WST) (MD −0.78, 95% CI [−1.07, −0.50], P < 0.00001 ), the video fluoroscopic swallowing study (VFSS) (MD 1.47, 95% CI [1.11, 1.84], P < 0.00001 ), the Ichiro Fujishima Rating Scale (IFRS) (MD 1.94, 95% CI [1.67, 2.22], P < 0.00001 ), and the incidence of aspiration pneumonia (IAP) (OR 0.20, 95% CI [0.06, 0.61], P = 0.005 ). Conclusions. The results showed that EA was better than the control treatment in terms of the effective rate, WST, VFSS, IFRS, and IAP of dysphagia after stroke. Strict evaluation standards and high-quality RCT designs are necessary for further exploration.

The impact of PM2.5 on lung function in adults with asthma

2020 ◽  
Vol 24 (6) ◽  
pp. 570-576
Author(s):  
L. Qibin ◽  
L. Yacan ◽  
J. Minli ◽  
Z. Meixi ◽  
L. Chengye ◽  
...  
Keyword(s):  
Lung Function ◽  
Meta Analysis ◽  
Forced Expiratory Volume ◽  
Risk Of Bias ◽  
Biomedical Literature ◽  
Knowledge Infrastructure ◽  
Acute Asthma Exacerbation ◽  
Pm2.5 Exposure ◽  
The Impact ◽  
Chinese National Knowledge Infrastructure

OBJECTIVE: To conduct a systematic review of the literature and assess the effect of PM2.5 (particulate matter with diameter <2.5 μm) exposure on lung function in adults with asthma.METHODS: We searched all literature published between 1 January 2010 and 26 March 2019 in the EMBASE, PubMed, Cochrane Central Library, Chinese National Knowledge Infrastructure (CNKI), Wanfang and Chinese Biomedical Literature (CBM) databases. The studies were assessed for analytic methods, risk of bias and results of statistical analysis.RESULTS: The selected studies all had a low or moderate risk of bias. Overall, PM2.5 exposure was positively associated with a decrease in forced expiratory volume in 1 sec (FEV1)/forced vital capacity (FVC) in adults with asthma (standardised mean difference 0.20, 95% CI 0.02–0.38; P = 0.03).CONCLUSION: We observed a negative correlation between PM2.5 exposure and FEV1/FVC in patients with asthma. Our meta-analysis provides evidence suggesting that PM2.5 is a risk factor for acute asthma exacerbation in adults.

scholarly journals Manual Acupuncture for Optic Atrophy: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Fang-Yuan Zhi ◽  
Jie Liu ◽  
Xiao-Peng Ma ◽  
Jue Hong ◽  
Ji Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Optic Atrophy ◽  
Meta Analysis ◽  
Biomedical Literature ◽  
Cochrane Library ◽  
Controlled Clinical Trial ◽  
Manual Acupuncture ◽  
Knowledge Infrastructure ◽  
Clinical Trials Registry

Objectives. This systematic review aims to critically evaluate the efficacy of manual acupuncture for optic atrophy. Eight English and Chinese databases, including Cochrane Library, EMbase, PubMed, Chinese National Knowledge Infrastructure (CNKI), Wanfang Database, China Science and Technology Journal Database (VIP), and Chinese Biomedical Literature Database (CBM), as well as ongoing trials registered with the WHO International Clinical Trials Registry Platform, were searched to identify eligible randomized controlled trials (RCTs) studying manual acupuncture for optic atrophy compared to medication alone. The quality of evidence was assessed using Cochrane Collaboration’s risk of bias tool. Meta-analysis was performed using Review Manager version 5.3. Nine studies were identified and included for meta-analysis. The meta-analysis showed significant differences in favor of manual acupuncture or manual acupuncture plus medication compared with medication alone in the following outcome measures: visual acuity (MD = 0.18, 95% CI [0.17, 0.20], P < 0.00001), mean sensitivity of visual field (MD = 2.11, 95% CI [1.90, 2.32], P < 0.00001), the latent period of P-VEP100 (MD = -6.80, 95% CI [-8.94, -4.66], P < 0.00001), the total effectiveness (264 eyes) (OR = 3.22, 95% CI [1.88, 5.51], P<0.0001), and the total effectiveness (344 participants) (OR = 4.29, 95% CI [2.56, 7.19], P < 0.00001). Despite statistical advantages of manual acupuncture in the literature, due to serious methodological flaws in study design, it cannot be concluded that manual acupuncture is more effective than medicine alone. It is essential that a properly controlled clinical trial is designed and controls are established to exclude placebo effects.

scholarly journals The Effectiveness of Laid-back Position on Lactation Related Nipple problems and comfort: A meta-analysis

2020 ◽  
Author(s):  
Zhi WANG ◽  
Qiuyue LIU ◽  
Lihua MIN ◽  
Xiaorong MAO
Keyword(s):  
Meta Analysis ◽  
Current Evidence ◽  
Cochrane Library ◽  
Control Group ◽  
International Consensus ◽  
Factors Affecting ◽  
Key Words Breast ◽  
Knowledge Infrastructure ◽  
Chinese National Knowledge Infrastructure

Abstract Background The importance of breastfeeding for maternal and child health has become an international consensus. However, it has been found that lactation-related nipple problems are common and there are some important factors affecting the effectiveness of breastfeeding. Multiple studies recommended the laid-back breastfeeding, but the researches are on various levels of quality and the results are controversial.Methods We systematically searched the following twelve databases: Cochrane Library, EMBASE, Medline, Ovid, PubMed, Web of Science, CINAHL, Scopus, SinoMed, Chinese National Knowledge Infrastructure (CNKI), WanFang, and VIP from inception to January 28,2020. All studies reporting the laid-back breastfeeding or biological nurturing were considered, regardless of they are randomized controlled trials. Two trained investigators independently evaluated the quality of the included the articles and screened the data. All the data were analyzed separately using Review Manager Version 5.3 and STATA/SE Version 15.1. Results A total of 12 studies involving 1,936 groups of postpartum women and their newborns were included. The results of meta-analysis showed that nipple trauma (RR = 0.47; 95% CI 0.29,0.75; p < 0.002), nipple pain (RR = 0.25; 95% CI 0.20,0.32; p < 0.00001), the correct posture of latching (RR = 1.22; 95% CI 1.11,1.33; p < 0.00001)and position comfort (ES = 0.01; 95%CI -0.28,0.30; p = 0.006) of experimental group were all better than control group, and the differences were statistically significant ( p < 0.05), which indicates that the laid-back position has a positive effect on maternal breastfeeding. Conclusion Laid-back position has significant advantages in decreasing the incidence of nipple trauma and nipple pain compared with traditional breastfeeding postures, and it appears that laid-back position is conducive to the correct posture of latching. However, current evidence does not show different breastfeeding outcomes in the two groups of position comfort. Laid-back position is helpful to solve lactation-related nipple problems and it can be used as a recommended position for breastfeeding. Key words: Breast-feeding, Biological Nurturing, Laid-back Breastfeeding, Meta-Analysis

scholarly journals The Effectiveness of Laid-back Position on Lactation Related Nipple problems and comfort: A meta-analysis

2020 ◽  
Author(s):  
Zhi WANG ◽  
Qiuyue LIU ◽  
Lihua MIN ◽  
Xiaorong MAO
Keyword(s):  
Meta Analysis ◽  
Current Evidence ◽  
Cochrane Library ◽  
Correct Position ◽  
International Consensus ◽  
Factors Affecting ◽  
Knowledge Infrastructure ◽  
Chinese National Knowledge Infrastructure ◽  
Positive Effect

Abstract Background The importance of breastfeeding for maternal and child health has become an international consensus. However, it has been found that lactation-related nipple problems are common and there are some important factors affecting the breastfeeding. Multiple studies recommended the laid-back breastfeeding, but they are on various levels of quality and the results are inconclusive. Methods We systematically searched the following twelve databases: Cochrane Library, EMBASE, Medline, Ovid, PubMed, Web of Science, CINAHL, Scopus, SinoMed, Chinese National Knowledge Infrastructure (CNKI), WanFang, and VIP from inception to January 28,2020. All studies regarding the laid-back breastfeeding or biological nurturing were considered, regardless of whether they are randomized controlled trials or not. Two trained investigators independently evaluated the quality of the selected articles and screened the data. All the data were analyzed separately using Review Manager Version 5.3 and STATA/SE Version 15.1.Results A total of 12 studies involving 1,936 groups of postpartum women and their newborns were included. The results of meta-analysis showed that nipple pain (RR = 0.24; 95% CI 0.14,0.40; p < 0.00001), nipple trauma (RR = 0.47; 95% CI 0.29,0.75; p = 0.002), the correct position of latching (RR = 1.22; 95% CI 1.11,1.33; p < 0.00001) and position comfort (ES = 0.09; 95% CI -0.63,0.81; p = 0.000) of experimental groups were all better than that of the control groups, and the differences were statistically significant (p < 0.05), which indicate that the laid-back position has a positive effect on maternal breastfeeding.Conclusion Laid-back position has been proved to related with decreasing the incidence of nipple trauma and nipple pain compared with traditional breastfeeding positions, and it appears that laid-back position is conducive to the correct position of latching. However, current evidence does not show different breastfeeding outcomes in the two groups of position comfort. Laid-back position is helpful to solve lactation-related nipple problems and it can be used as a recommended position for breastfeeding.

scholarly journals A Data Mining-Based Analysis of Medication Rules in Treating Bone Marrow Suppression by Kidney-Tonifying Method

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Xing You ◽  
Yinkun Xu ◽  
Jin Huang ◽  
Yaofeng Zhi ◽  
Fengzhen Wu ◽  
...  
Keyword(s):  
Data Mining ◽  
Bone Marrow ◽  
Chinese Medicine ◽  
High Frequency ◽  
Bone Marrow Suppression ◽  
Biomedical Literature ◽  
Astragali Radix ◽  
Knowledge Infrastructure ◽  
Pathogenic Factors ◽  
Chinese National Knowledge Infrastructure

Objective. To investigate the rule of kidney-tonifying method in Chinese medicine for the treatment of bone marrow suppression (BMS), in order to provide evidence and references for the clinical application of herbs and formulae. Design. Collecting and sorting the information about the treatment of BMS related to kidney-tonifying (Bushen) method in Chinese medicine literatures on databases including Chinese National Knowledge Infrastructure (CNKI), and Chinese Biomedical Literature Database (CBM), establishing a database of BMS treating formulae after radiotherapy and chemotherapy with traditional Chinese medicine (TCM) kidney-tonifying method, and finally applying the relevant theories and techniques of data mining to analyze the medication rules of it. Results. A total of 239 formulae and 202 herbs were included in this database, in which the herbs occurred 2,602 times in general. The high frequency herbs included Astragali Radix (Huangqi), Atractylodis Macrocephalae Rhizoma (Baizhu), and Ligustri Lucidi Fructus (Nvzhenzi). The main herb categories were deficiency-tonifying herbs, blood-activating herbs, dampness-draining diuretic herbs, heat-clearing herbs, and digestant herbs. Deficiency-tonifying herbs accounted for 64.60% of the total number. A total of 8 clustering formulae are summarized according to cluster analysis and 26 herb suits association rules are identified by Apriori algorithm. Conclusion. The treatment of BMS is mainly based on the method of invigorating the spleen and tonifying the kidney and liver to strengthen healthy qi, supplementing with blood-activating herbs, and dampness-draining diuretic herbs to eliminate pathogenic factors.

scholarly journals Acupuncture for Obstructive Sleep Apnea (OSA) in Adults: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Liaoyao Wang ◽  
Jia Xu ◽  
Yijun Zhan ◽  
Jian Pei
Keyword(s):  
Subgroup Analysis ◽  
Assessment Tool ◽  
Meta Analysis ◽  
Biomedical Literature ◽  
Cochrane Library ◽  
China National Knowledge Infrastructure ◽  
Knowledge Infrastructure ◽  
Obstructive Sleep ◽  
Clinically Significant

Objective. Our aim was to assess the efficacy and safety of acupuncture for OSA patients with various severities of the disorder. Methods. Eight databases including PubMed, Cochrane Library, EMBASE, Web of Science, China National Knowledge Infrastructure (CNKI), Chongqing VIP (CQVIP), Wanfang Data, and Chinese Biomedical Literature Database (CBM) were comprehensively searched till July 2019. Randomized controlled trials (RCTs) testing acupuncture in the treatment of OSA were eligible for inclusion. Studies were selected for inclusion, and data were extracted by two authors independently. The Cochrane Collaboration’s Risk of Bias Assessment Tool and RevMan software (version 5.3) were used to evaluate the quality of studies and conduct statistical analysis. Results. Nine RCTs with 584 participants were included. The trials covered acupuncture and electropuncture. Acupuncture caused clinically significant reductions in AHI (MD: -6.18; 95% CI: -9.58 to -2.78; Z=3.56, P=0.0004) as well as in ESS (MD: -2.84; 95% CI: -4.80 to -0.16, Z=2.09, P=0.04). AHI was reduced more in the subgroup analysis of moderate OSA patients (MD: -9.44; 95% CI: -12.44 to -6.45; Z=6.18, P<0.00001) and severe OSA patients (MD: -10.09; 95% CI: -12.47 to -7.71; Z=8.31, P<0.00001). ESS was also reduced more in the subgroup analysis of moderate OSA patients (MD: -2.40; 95% CI: -3.63 to -1.17; Z=3.83, P=0.0001) and severe OSA patients (MD: -4.64; 95% CI: -5.35 to -3.92; Z=12.72, P<0.00001). Besides, acupuncture had a beneficial effect on LSaO2 (MD: 5.29; 95% CI: 2.61 to 7.97; Z=3.86, P=0.0001). The outcome of AHI and LSaO2 yielded consistent results after sensitivity analysis, but the direction of the outcome of ESS was reversed. And the quality of evidence was mainly low to very low. Conclusions. Acupuncture therapy is effective for OSA patients in reducing AHI and ESS and in improving the LSaO2 of various severities, especially in moderate and severe OSA patients. High-quality trials are urgently needed.

scholarly journals Effectiveness and Safety of Plum - Blossom Needle in the Treatment of Myopia：A Protocol for Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Siyuan Zhu ◽  
Jun Xiong ◽  
Jun Chen ◽  
Genhua Tang ◽  
Lunbin Lu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Scientific Journal ◽  
Biomedical Literature ◽  
Systematic Evaluation ◽  
Cochrane Library ◽  
China National Knowledge Infrastructure ◽  
Myopia Progression ◽  
Knowledge Infrastructure ◽  
The Cochrane Library

Abstract Background: In recent years, the prevalence of myopia has increased significantly, and it has become one of the major eye diseases that cause visual impairment in the world,which is particularly prominent among young people. And uncorrected myopia is the leading cause of blindness.The purpose of this study is to evaluate the efficacy and safety of plum-blossom needle in delaying adolescent myopia progression through systematic evaluation.Methods and analysis:The following electronic databases will be searched from inception to July 2020 regardless of publication status and language: Medline, EMBASE, Web of Science, the Cochrane Library, PubMed, China National Knowledge Infrastructure (CNKI), China Biology Medicine (CBM), Chinese Scientific Journal Database (VIP), Wanfang Database, Chinese Biomedical Literature Database (CBLD), Chinese Science and Technology Periodical Database (CSTPD). RCT registration websites, including http://www.ClinicalTrials.gov and http://www.chictr.org.cn, will also be searched. Review Manager V.5.4 will be used to analysis the statistic. Two reviewers will independently select studies, extract and code the data, assess risk of bias of the included studies, evaluate the quality of evidence for outcomes.Discussion:So far, many studies have been conducted on the treatment of adolescent myopia with plum-blossom needles. However, there is still no clear conclusion on the effectiveness and safety of plum-blossom needles in the treatment of juvenile myopia.In this systematic review and meta-analysis, available data will be pooled together to further inform research and clinical practice.Systematic review registration: Inplasy protocol 202080026

scholarly journals The Effectiveness and Safety of Moxibustion for Peripheral Facial Paralysis：A Protocol for Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Shanshan Xiang ◽  
Ting Fang ◽  
Changan Ren ◽  
Junnan Qi ◽  
Zheng Guo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Document Retrieval ◽  
Effective Rate ◽  
Cochrane Library ◽  
Peripheral Facial Paralysis ◽  
Randomized Controlled ◽  
Knowledge Infrastructure ◽  
Chinese National Knowledge Infrastructure

Abstract Background: Moxibustion has been used in treating patients with Peripheral Facial Paralysis(PFP), but its effectiveness and safety have not been systematically evaluated. Therefore, the objective of this review is to comprehensively assess the effectiveness and safety of moxibustion for PFP.Methods: We will conduct a systematic document retrieval of databases from inception to March 18, 2021, including Embase, Cochrane Library, Pubmed, Chinese databases SinoMed, Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Database and Wanfang Data (WF). Reviewers will independently retrieve databases, identify trials, extract data, and evaluate the quality of eligible randomized controlled trials(RCTs). The outcomes will include: the effective rate, the House-Brackmann (H-B) score, Facial Disability Index (FDI), and side effects. The quality of eligible RCT will be assessed by the Cochrane risk-of-bias. Meta-analysis will be processed by the Cochrane Collaboration’s RevMan 5.3.0.Discussion: This review will provide comprehensive evidence of moxibustion for PFP.Systematic review registration: PROSPERO CRD42020207068

scholarly journals Long-Term Macrolide Treatment for Non-Cystic Fibrosis Bronchiectasis in Children: A Meta-Analysis

2021 ◽  
Author(s):  
Eun Lee ◽  
In Suk Sol ◽  
Jong Deok Kim ◽  
Hyeon-Jong Yang ◽  
Taek Ki Min ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Bacterial Resistance ◽  
Meta Analysis ◽  
Mean Difference ◽  
Cochrane Library ◽  
Resistant Bacteria ◽  
Knowledge Infrastructure ◽  
Term Administration ◽  
Chinese National Knowledge Infrastructure

Abstract Recurrent bacterial infection causes frequent exacerbations of Bronchiectasis (BE). The effectiveness and safety of macrolide long-term administration in BE remains controversial, especially in children with little treatment to prevent exacerbation. We conducted this meta-analysis to determine the usefulness of long-term macrolide in pediatric BE. We searched PubMed, Cochrane Library databases, Embase, KoreaMed, Igaku Chuo Zasshi, and Chinese National Knowledge Infrastructure databases. We identified randomized controlled trials (RCTs) on long-term macrolide treatment (≥ 4 weeks) in non-cystic fibrosis BE in children aged < 18 years. The primary outcome was frequency of acute exacerbation; secondary outcomes were changes in pulmonary function, sputum scores, and adverse events including bacterial resistance. We included four RCTs. Long-term macrolide treatment showed a significant decrease in the frequency of exacerbation (odds ratio [OR], 0.30; 95% confidence interval [CI], 0.10 to 0.87), mean number of exacerbations per patient (mean difference, -1.40; 95% CI, -2.26 to -0.54) and sputum purulence score (mean difference, -0.78; 95% CI, -1.32 to -0.24). However, long-term macrolide treatment was accompanied by increased carriage of azithromycin-resistant bacteria (OR, 7.13). Long-term macrolide administration prevents exacerbation of BE in children, but risks increasing antibiotic resistance. Benefits and risks should be weighed and determined on a patient-by-patient basis.

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