scholarly journals Observation on the Clinical Effect of Acupuncture and Moxibustion Combined with Repeated Transcranial Magnetic Stimulation on Facial Paralysis

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Lina Liang ◽  
Feng Qiang
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Facial Paralysis ◽  
Clinical Efficacy ◽  
Magnetic Stimulation ◽  
Clinical Effect ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Measurement Scale ◽  
Acupuncture And Moxibustion ◽  
The Poor ◽  
Better Than

In view of the difficulty in the treatment of facial paralysis and the poor effect of traditional methods, this paper proposes a strategy based on acupuncture and repeated transcranial magnetic stimulation. The three groups of patients were tested for efficacy using the H-B scale and the symptom characteristics and physical signs measurement scale. Acupuncture combined with repetitive transcranial magnetic stimulation can improve the clinical efficacy of facial paralysis. And it is significantly better than traditional paralysis and repetitive translational magnetic stimulation in the degree of healing.

scholarly journals Functional and Structural Connectivity Between the Left Dorsolateral Prefrontal Cortex and Insula Could Predict the Antidepressant Effects of Repetitive Transcranial Magnetic Stimulation

2021 ◽  
Vol 15 ◽  
Author(s):  
Yixiao Fu ◽  
Zhiliang Long ◽  
Qinghua Luo ◽  
Zhen Xu ◽  
Yisijia Xiang ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Clinical Efficacy ◽  
Magnetic Stimulation ◽  
Dorsolateral Prefrontal Cortex ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Structural Connectivity ◽  
Left Dlpfc ◽  
Dorsolateral Prefrontal ◽  
Connectivity Strength

BackgroundThe efficacy of repetitive transcranial magnetic stimulation (rTMS) in depression is nonuniform across patients. This study aims to determine whether baseline neuroimaging characters can provide a pretreatment predictive effect for rTMS.MethodsTwenty-seven treatment-naive patients with major depressive disorder (MDD) were enrolled and scanned with resting-state functional magnetic resonance imaging (fMRI) and diffusion tensor imaging. Clinical symptoms were assessed pre- and post-rTMS. Functional and structural connectivity between the left dorsolateral prefrontal cortex (DLPFC) and bilateral insula were measured, and the connectivity strength in each modality was then correlated to the clinical efficacy of rTMS.ResultsWhen the coordinates of left DLPFC were located as a node in the central executive network, the clinical efficacy of rTMS was significantly correlated with the functional connectivity strength between left DLPFC and bilateral insula (left insula: r = 0.66; right insula: r = 0.65). The structural connectivity strength between the left DLPFC and left insular cortex also had a significantly positive correlation with symptom improvement (rs = 0.458).ConclusionThis study provides implications that rTMS might act more effectively when the pretreatment functional and structural connectivity between the insula and left DLPFC is stronger.

scholarly journals Repetitive Transcranial Magnetic Stimulation on Chronic Tinnitus: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Zhengrong Liang ◽  
Gui Cheng ◽  
Lingfei Huang ◽  
Tao Zhang ◽  
Haidi Yang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Transcranial Magnetic Stimulation ◽  
Publication Bias ◽  
Clinical Efficacy ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Meta Analysis ◽  
Chronic Tinnitus ◽  
Efficacy And Safety ◽  
Post Intervention

Abstract Background: Although the clinical efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) in the treatment of chronic tinnitus have been frequently examined, the results remain contradictory. Therefore, we performed a systematic review and meta-analysed clinical trials examining the effects of rTMS to evaluate its clinical efficacy and safety.Methods: Studies of rTMS for chronic tinnitus were retrieved from PubMed, Embase, and Cochrane Library through April 2020. Review Manager 5.3 software was employed for data synthesis, and Stata 13.0 software was used for analyses of publication bias and sensitivity.Results: Twenty-nine randomized studies involving 1,228 chronic tinnitus patients were included. Compared with sham-rTMS, rTMS exhibited significant improvements in the tinnitus handicap inventory (THI) scores at 1 week (mean difference [MD]: -7.92, 95% confidence interval [CI]: -14.18, -1.66), 1 month (MD: -8.52, 95% CI: -12.49, -4.55), and 6 months (MD: -6.53, 95% CI: -11.406, -1.66) post intervention; there were significant mean changes in THI scores at 1 month (MD: -14.86, 95% CI: -21.42, -8.29) and 6 months (MD: -16.37, 95% CI: -20.64, -12.11) post intervention, and the tinnitus questionnaire (TQ) score at 1 week post intervention (MD: -8.54, 95% CI: -15.56, -1.52). Nonsignificant efficacy of rTMS was found regarding the THI score 2 weeks post intervention (MD: -1.51, 95% CI: -13.42, -10.40); the mean change in TQ scores 1 month post intervention (MD: -3.67, 95% CI: -8.56, 1.22); TQ scores 1 (MD: -8.97, 95% CI: -20.41, 2.48) and 6 months (MD: -7.02, 95% CI: -18.18, 4.13) post intervention; and adverse events (odds ratios [OR]: 1.11, 95% CI: 0.51, 2.42). Egger's and Begg's tests indicated no publication bias (P = 0.925).Conclusion: This meta-analysis demonstrated that rTMS is effective for chronic tinnitus; however, its safety needs more validation. Restrained by the insufficient number of included studies and the small sample size, more large randomized double-blind multi-centre trials are needed for further verification.

scholarly journals Clinical efficacy and safety of repetitive transcranial magnetic stimulation in acute bipolar depression

2016 ◽  
Vol 15 (1) ◽  
pp. 85-86 ◽  
Author(s):  
Alexander McGirr ◽  
Sneha Karmani ◽  
Rashmi Arsappa ◽  
Marcelo T. Berlim ◽  
Jagadisha Thirthalli ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Clinical Efficacy ◽  
Magnetic Stimulation ◽  
Bipolar Depression ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Efficacy And Safety

scholarly journals Repetitive Transcranial Magnetic Stimulation on Chronic Tinnitus: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Zhengrong Liang ◽  
Haidi Yang ◽  
Gui Cheng ◽  
Lingfei Huang ◽  
Tao Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Transcranial Magnetic Stimulation ◽  
Publication Bias ◽  
Clinical Efficacy ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Meta Analysis ◽  
Chronic Tinnitus ◽  
Efficacy And Safety ◽  
Post Intervention

Abstract Background: Although the clinical efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) in the treatment of chronic tinnitus have been frequently examined, the results remain contradictory. Therefore, we performed a systematic review and meta-analysed clinical trials examining the effects of rTMS to evaluate its clinical efficacy and safety.Methods: Studies of rTMS for chronic tinnitus were retrieved from PubMed, Embase, and Cochrane Library through April 2020. Review Manager 5.3 software was employed for data synthesis, and Stata 13.0 software was used for analyses of publication bias and sensitivity.Results: Twenty-nine randomized studies involving 1,228 chronic tinnitus patients were included. Compared with sham-rTMS, rTMS exhibited significant improvements in the tinnitus handicap inventory (THI) scores at 1 week (mean difference [MD]: -7.92, 95% confidence interval [CI]: -14.18, -1.66), 1 month (MD: -8.52, 95% CI: -12.49, -4.55), and 6 months (MD: -6.53, 95% CI: -11.406, -1.66) post intervention; there were significant mean changes in THI scores at 1 month (MD: -14.86, 95% CI: -21.42, -8.29) and 6 months (MD: -16.37, 95% CI: -20.64, -12.11) post intervention, and the tinnitus questionnaire (TQ) score at 1 week post intervention (MD: -8.54, 95% CI: -15.56, -1.52). Nonsignificant efficacy of rTMS was found regarding the THI score 2 weeks post intervention (MD: -1.51, 95% CI: -13.42, -10.40); the mean change in TQ scores 1 month post intervention (MD: -3.67, 95% CI: -8.56, 1.22); TQ scores 1 (MD: -8.97, 95% CI: -20.41, 2.48) and 6 months (MD: -7.02, 95% CI: -18.18, 4.13) post intervention; and adverse events (odds ratios [OR]: 1.11, 95% CI: 0.51, 2.42). Egger's and Begg's tests indicated no publication bias (P = 0.925).Conclusion: This meta-analysis demonstrated that rTMS is effective for chronic tinnitus; however, its safety needs more validation. Restrained by the insufficient number of included studies and the small sample size, more large randomized double-blind multi-centre trials are needed for further verification.

scholarly journals Repetitive Transcranial Magnetic Stimulation on  Chronic Tinnitus: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Zhengrong Liang ◽  
Gui Cheng ◽  
Lingfei Huang ◽  
Tao Zhang ◽  
Haidi Yang ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Publication Bias ◽  
Clinical Efficacy ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Meta Analysis ◽  
Chronic Tinnitus ◽  
Efficacy And Safety ◽  
Post Intervention ◽  
The Mean

Abstract Background: Although the clinical efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) in the treatment of chronic tinnitus have been frequently examined, the results remain controversial. Therefore, we systematically meta-classified clinical trials concerning the effects of rTMS to evaluate its clinical efficacy and safety. Methods: Studies of rTMS for chronic tinnitus were retrieved in PubMed, Embase, and Cochrane Library due April 2020. Review Manager 5.3 software was employed for data synthesis and Stata 13.0 software for analyses of publication bias and sensitivity. Results: Twenty-nine randomized studies representing 1,228 chronic tinnitus patients were included. Compared with sham-rTMS, rTMS exhibited significant improvements in the tinnitus handicap inventory (THI) score 1-week (mean difference [MD] -7.92, 95% confidence interval [CI] -14.18,-1.66), 1-month (MD -8.52, 95% CI -12.49, -4.55), and 6-month post-intervention (MD -6.53, 95% CI -11.406,-1.66), the mean change in THI scores 1- (MD -14.86, 95% CI -21.42,-8.29) and 6-month post-intervention (MD -16.37, 95% CI -20.64,-12.11), and the tinnitus questionnaire (TQ) score 1-week post-intervention (MD -8.54, 95% CI -15.56,-1.52). Non-significant efficacy of rTMS was found concerning the THI score 2-week post-intervention (MD -1.51, 95% CI -13.42,-10.40), the mean change in TQ scores 1-month post-intervention (MD -3.67, 95% CI -8.56,1.22), the TQ score 1- (MD -8.97, 95% CI -20.41,2.48) and 6-month post-intervention (MD -7.02, 95% CI -18.18,4.13), and adverse events (odds ratios [OR] 1.11, 95% CI 0.51,2.42). The Egger's and Begg's tests indicated no publication bias ( P = 0.925). Conclusion: This meta-analysis demonstrates that rTMS is effective for chronic tinnitus; however, its safety needs more validations. Restrained by the limited number of included studies and the small sample size, more large randomized double-blind multi-center trials are needed for further verification.

scholarly journals Repetitive transcranial magnetic stimulation on chronic tinnitus: a systematic review and meta-analysis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhengrong Liang ◽  
Haidi Yang ◽  
Gui Cheng ◽  
Lingfei Huang ◽  
Tao Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Transcranial Magnetic Stimulation ◽  
Publication Bias ◽  
Clinical Efficacy ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Meta Analysis ◽  
Chronic Tinnitus ◽  
Efficacy And Safety ◽  
Post Intervention

Abstract Background Although the clinical efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) in the treatment of chronic tinnitus have been frequently examined, the results remain contradictory. Therefore, we performed a systematic review and meta-analysed clinical trials examining the effects of rTMS to evaluate its clinical efficacy and safety. Methods Studies of rTMS for chronic tinnitus were retrieved from PubMed, Embase, and Cochrane Library through April 2020. Review Manager 5.3 software was employed for data synthesis, and Stata 13.0 software was used for analyses of publication bias and sensitivity. Results Twenty-nine randomized studies involving 1228 chronic tinnitus patients were included. Compared with sham-rTMS, rTMS exhibited significant improvements in the tinnitus handicap inventory (THI) scores at 1 week (mean difference [MD]: − 7.92, 95% confidence interval [CI]: − 14.18, − 1.66), 1 month (MD: -8.52, 95% CI: − 12.49, − 4.55), and 6 months (MD: -6.53, 95% CI: − 11.406, − 1.66) post intervention; there were significant mean changes in THI scores at 1 month (MD: -14.86, 95% CI: − 21.42, − 8.29) and 6 months (MD: -16.37, 95% CI: − 20.64, − 12.11) post intervention, and the tinnitus questionnaire (TQ) score at 1 week post intervention (MD: -8.54, 95% CI: − 15.56, − 1.52). Nonsignificant efficacy of rTMS was found regarding the THI score 2 weeks post intervention (MD: -1.51, 95% CI: − 13.42, − 10.40); the mean change in TQ scores 1 month post intervention (MD: -3.67, 95% CI: − 8.56, 1.22); TQ scores 1 (MD: -8.97, 95% CI: − 20.41, 2.48) and 6 months (MD: -7.02, 95% CI: − 18.18, 4.13) post intervention; and adverse events (odds ratios [OR]: 1.11, 95% CI: 0.51, 2.42). Egger’s and Begg’s tests indicated no publication bias (P = 0.925). Conclusion This meta-analysis demonstrated that rTMS is effective for chronic tinnitus; however, its safety needs more validation. Restrained by the insufficient number of included studies and the small sample size, more large randomized double-blind multi-centre trials are needed for further verification.

Effects of repetitive transcranial magnetic stimulation (rTMS) on aphasia in stroke patients: A systematic review and meta-analysis

2021 ◽  
pp. 026921552199955
Author(s):  
Jun Zhang ◽  
Dongling Zhong ◽  
Xili Xiao ◽  
Li Yuan ◽  
Yuxi Li ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Meta Analysis ◽  
Low Frequency ◽  
Risk Of Bias ◽  
Stroke Patients ◽  
Language Recovery ◽  
Better Than

Objective: To evaluate the effects and safety of repetitive transcranial magnetic stimulation (rTMS) on aphasia in stroke patients. Methods: We searched databases from inception to January 28, 2021. Randomized control trials investigating the effects and safety of rTMS for aphasia patients after stroke were included. Study screening, data extraction, and risk of bias assessment were performed independently by two reviewers. Meta-analysis was conducted with Review Manager 5.3 software. The quality of the evidence was assessed by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Results: Twenty-eight studies with 1287 patients were included. All studies were assessed at low or unclear risk of bias in one or more domains. The meta-analysis exhibited rTMS was better than sham rTMS and conventional rehabilitation in language recovery. Low-frequency rTMS showed greater improvement in language recovery except for comprehension than sham rTMS. Low-frequency and bilateral rTMS were superior to conventional rehabilitation in language recovery. High-frequency rTMS was no better than sham rTMS and conventional rehabilitation for improving aphasia. The rTMS had better effects in naming, comprehension and aphasia quotient at 20 sessions. Eleven studies reported rTMS was safe for aphasia patients after stroke. The quality of evidence for all outcomes was low or very low, and publication bias may exist. Conclusions: rTMS may be relatively effective and safe for aphasia patients after stroke. However, these findings should be treated with caution due to high heterogeneity and potential biases.

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