scholarly journals A Novel Method for Preparation of Carrageenan/Fish Scale Collagen/Allopurinol Biocomposite Film

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Quoc Manh Vu ◽  
Thuy Chinh Nguyen ◽  
Duong My Ngoc Dam ◽  
Quoc Trung Vu ◽  
Trong Lu Le ◽  
...  

Biopolymers such as carrageenan or collagen can be used as carriers for loading a drug to enhance a drug’s bioavailability. In this work, allopurinol was loaded on a carrageenan/collagen blend and the carrageenan/collagen/allopurinol (CCA) biocomposite films were prepared using the ionic gelation method combined with the 3D printing method using carrageenan/collagen/allopurinol gel as a 3D printing ink material. The advantages of the 3D printing method are the ease in shaping the design of films and the ease in controlling the thickness of films. The results of infrared (IR) spectroscopy and field emission scanning electron microscopy (FESEM) analyses showed that the CCA biocomposite films have a regular structure, and the functional groups of components in the biocomposites can interact with each other. After 30 minutes of immersion in distilled water and pH buffer solution, the biocomposite films swelled and disintegrated. The carrageenan/collagen blend can control the release of allopurinol in simulated body fluids. In addition, the drug release kinetic models reflecting the release process of allopurinol from CCA biocomposite films in simulated body fluids have also been calculated.

2020 ◽  
Author(s):  
Eshani Hettiarachchi ◽  
◽  
Shaylene Paul ◽  
Shaylene Paul ◽  
Milton Das ◽  
...  

2020 ◽  
Author(s):  
Dyah Hikmawati ◽  
Tiandini Dwi Sundari ◽  
Aminatun ◽  
Inten Firdhausi Wardhani
Keyword(s):  

Author(s):  
Simon Weidert ◽  
Sebastian Andress ◽  
Christoph Linhart ◽  
Eduardo M. Suero ◽  
Axel Greiner ◽  
...  

A correction to this paper has been published: https://doi.org/10.1007/s11548-021-02348-7


CrystEngComm ◽  
2021 ◽  
Author(s):  
Shuqin Jiang ◽  
Yuanyuan Cao ◽  
Chenxi Zong ◽  
Yuanfeng Pang ◽  
Zhiwen Sun

The regulation effect of Mg2+ on HAP crystallization is closely related to the adding time of Mg2+. The introduction of Mg2+ in the ACP unstable stage is unable to inhibit HAP crystallization.


Author(s):  
Jung-Su Kim ◽  
Dong-Soo Kim ◽  
Min-Cheol Lee
Keyword(s):  

2016 ◽  
Author(s):  
P. J. Wang ◽  
J. A. Yeh ◽  
W. Y. Hsu ◽  
Y. C. Cheng ◽  
W. Lee ◽  
...  

2021 ◽  
Vol 11 (2) ◽  
pp. 563
Author(s):  
Tuong Phuoc Tho ◽  
Nguyen Truong Thinh

In construction, a large-scale 3D printing method for construction is used to build houses quickly, based on Computerized Aid Design. Currently, the construction industry is beginning to apply quite a lot of 3D printing technologies to create buildings that require a quick construction time and complex structures that classical methods cannot implement. In this paper, a Cable-Driven Parallel Robot (CDPR) is described for the 3D printing of concrete for building a house. The CDPR structures are designed to be suitable for 3D printing in a large workspace. A linear programming algorithm was used to quickly calculate the inverse kinematic problem with the force equilibrium condition for the moving platform; this method is suitable for the flexible configuration of a CDPR corresponding to the various spaces. Cable sagging was also analyzed by the Trust-Region-Dogleg algorithm to increase the accuracy of the inverse kinematic problem for controlling the robot to perform basic trajectory interpolation movements. The paper also covers the design and analysis of a concrete extruder for the 3D printing method. The analytical results are experimented with based on a prototype of the CDPR to evaluate the work ability and suitability of this design. The results show that this design is suitable for 3D printing in construction, with high precision and a stable trajectory printing. The robot configuration can be easily adjusted and calculated to suit the construction space, while maintaining rigidity as well as an adequate operating space. The actuators are compact, easy to disassemble and move, and capable of accommodating a wide variety of dimensions.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Yangwei Wang ◽  
Peilun Lv ◽  
Jian Li ◽  
Liying Yu ◽  
Guodong Yuan ◽  
...  

Purpose This paper aims to propose a suitable atomizing solidification chitosan (CS) gel liquid extrusion molding technology for the three dimensional (3D) printing method, and experiments verify the feasibility of this method. Design/methodology/approach This paper mainly uses experimental means, combined with theoretical research. The preparation method, solidification forming method and 3D printing method of CS gel solution were studied. The CS gel printing mechanism and printing error sources are analyzed on the basis of the CS gel ink printing results, printing performance with different ratios of components by constructing a gel print prototype, experiments evaluating the CS gel printing technology and the effects of the process parameters on the scaffold formation. Findings CS printing ink was prepared; the optimal formula was found; the 3 D printing experiment of CS was completed; the optimal printing parameters were obtained; and the reliability of the forming prototype, printing ink and gel printing process was verified, which allowed for the possibility to apply the 3 D printing technology to the manufacturing of a CS gel structure. Originality/value This study can provide theoretical and technical support for the potential application of CS 3 D printed gels in tissue engineering.


2021 ◽  
Author(s):  
Alexey I. Kokshayskiy ◽  
Alexander B. Volodarskii ◽  
Natalia V. Shirgina ◽  
Natalia I. Odina ◽  
Alexander I. Korobov

2014 ◽  
Vol 604 ◽  
pp. 175-179 ◽  
Author(s):  
Lasma Poca ◽  
Arita Dubnika ◽  
Dagnija Loca ◽  
Liga Berzina-Cimdina

In the present study, thein vitrobioactivity of silver-doped hydroxyapatite (HAp/Ag) scaffolds was investigated. HAp/Ag was prepared using two different modified wet precipitation methods. The X-ray powder diffraction (XRD) results showed, that sintered HAp/Ag samples prepared using method (I) contain two phases HAp and Ag, but samples prepared by method (II) contain three different phases - HAp, Ag and AgO. After 2 month incubation period in simulated body fluid (SBF), surface of HAp/Ag scaffolds was coated with bone-like apatite. Thickness of bone-like apatite layer increased from 2 μm up to 32 μm, increasing the incubation period.


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