scholarly journals Early Localization of Bronchogenic Carcinoma

1994 ◽  
Vol 1 (2) ◽  
pp. 75-78 ◽  
Author(s):  
S. Lam ◽  
C. Macaulay ◽  
J. C. Leriche ◽  
N. Ikeda ◽  
B. Palcic
Keyword(s):  
Lung Cancer ◽  
Head And Neck Cancer ◽  
White Light ◽  
Small Cell ◽  
Severe Dysplasia ◽  
Small Cell Lung ◽  
Imaging Device ◽  
Normal Tissues ◽  
Resected Stage

The performance of a fluorescence imaging device was compared with conventional white-light bronchoscopy in 100 patients with lung cancer, 46 patients with resected stage I non-small cell lung cancer, 10 patients with head and neck cancer, and 67 volunteers who had smoked at least 1 pack of cigarettes per day for 25 years or more. Using differences in tissue autofluorescence between premalignant, malignant, and normal tissues, fluorescence bronchoscopy was found to detect significantly more areas with moderate/severe dysplasia or carcinoma in situ than conventional white-light bronchoscopy with a similar specificity. Multiple foci of dysplasia or cancer were found in 13–24% of these individuals. Fluorescence bronchoscopy may be an important adjunct to conventional bronchoscopic examination to improve our ability to detect and localize premalignant and early lung cancer lesions.

scholarly journals P17.01 Adaptive Elastic-Net Nomogram Predicting Disease-Free Survival in Resected Stage IIIA (N2) Non–Small Cell Lung Cancer

2021 ◽  
Vol 16 (3) ◽  
pp. S351
Author(s):  
C. Zhang ◽  
W. Feng ◽  
R. Hou ◽  
W. Zeng ◽  
Q. Zhang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Disease Free Survival ◽  
Small Cell ◽  
Small Cell Lung ◽  
Stage Iiia ◽  
Free Survival ◽  
Resected Stage ◽  
Adaptive Elastic Net ◽  
Disease Free

scholarly journals Prognostic Value of Tumor Size in Resected Stage IIIA-N2 Non-Small-Cell Lung Cancer

2020 ◽  
Vol 9 (5) ◽  
pp. 1307 ◽  
Author(s):  
Chih-Yu Chen ◽  
Bing-Ru Wu ◽  
Chia-Hung Chen ◽  
Wen-Chien Cheng ◽  
Wei-Chun Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Prognostic Factors ◽  
Tumor Size ◽  
Small Cell ◽  
Small Cell Lung ◽  
Stage Iiia ◽  
Pathologic Stage ◽  
The Mean ◽  
Eighth Edition ◽  
Resected Stage

The eighth edition of the American Joint Committee on Cancer (AJCC) staging system for lung cancer was introduced in 2017 and included major revisions, especially of stage III. For the subgroup stage IIIA-N2 non-small-cell lung cancer (NSCLC), surgical resection remains controversial due to heterogeneous disease entity. The aim of this study was to evaluate the clinicopathologic features and prognostic factors of patients with completely resected stage IIIA-N2 NSCLC. We retrospectively evaluated 77 consecutive patients with pathologic stage IIIA-N2 NSCLC (AJCC eighth edition) who underwent surgical resection with curative intent in China Medical University Hospital between 2006 and 2014. Survival analysis was conducted, using the Kaplan–Meier method. Prognostic factors predicting overall survival (OS) and disease-free survival (DFS) were analyzed, using log-rank tests and multivariate Cox proportional hazards models. Of the 77 patients with pathologic stage IIIA-N2 NSCLC examined, 35 (45.5%) were diagnosed before surgery and 42 (54.5%) were diagnosed unexpectedly during surgery. The mean age of patients was 59 years, and the mean length of follow-up was 38.1 months. The overall one-, three-, and five-year OS rates were 91.9%, 61.3%, and 33.5%, respectively. Multivariate analysis showed that tumor size <3 cm (hazards ratio (HR): 0.373, p = 0.003) and video-assisted thoracoscopic surgery (VATS) approach (HR: 0.383, p = 0.014) were significant predictors for improved OS. For patients with surgically treated, pathologic stage IIIA-N2 NSCLC, tumor size <3 cm and the VATS approach seemed to be associated with better prognosis.

Current issues in adjuvant chemotherapy for resected, stage IB non-small-cell lung cancer

2009 ◽  
Vol 5 (1) ◽  
pp. 19-22 ◽  
Author(s):  
Hossein Borghaei ◽  
Ranee Mehra ◽  
George Simon
Keyword(s):  
Lung Cancer ◽  
Adjuvant Chemotherapy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Stage Ib ◽  
Resected Stage

scholarly journals Heterogeneity of Met Assessed By Immunohistochemistry (Ihc) and Fluorescence-In-Situ Hybridization (Fish) in Nonsquamous Non-Small Cell Lung Cancer (Nsnsclc)

2014 ◽  
Vol 25 ◽  
pp. iv66
Author(s):  
D. Casadevall ◽  
J. Gimeno ◽  
S. Clavé ◽  
A. Taus ◽  
L. Pijuan ◽  
...  
Keyword(s):  
Lung Cancer ◽  
In Situ Hybridization ◽  
Small Cell Lung Cancer ◽  
Fluorescence In Situ Hybridization ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung
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