scholarly journals Synovial Sarcoma Mimicking Haemophilic Pseudotumour

Sarcoma ◽  
2006 ◽  
Vol 2006 ◽  
pp. 1-3 ◽  
Author(s):  
Haroon A. Mann ◽  
Andrew Hilton ◽  
Nicholas J. Goddard ◽  
Michael A. Smith ◽  
Brian Holloway ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Synovial Cell ◽  
Clinical Findings ◽  
Haemophilia A ◽  
Open Biopsy ◽  
Mri Scan ◽  
Cell Sarcoma ◽  
Soft Tissue Swelling ◽  
The Right ◽  
Mild Haemophilia

This is a case of a 36-year-old gentleman with haemophilia A who was presented with an acute atraumatic soft tissue swelling in the right thigh. Open biopsy was performed with the resultant diagnosis of a synovial cell sarcoma. Although the clinical findings were nonspecific they could easily have been found in a bleeding haemophilic pseudotumour. The findings reported on MRI scan initially were highly consistent with those present in patients with mild haemophilia. An important part of orthopaedic management in haemophilia is concerned with intraarticular and intramuscular bleeding. Haematomas are common and sarcomas are rare. However the absence of trauma should alert the clinician to the possibility that the abnormality may represent haemorrhage into a tumour and not just haematoma, even in a haemophilic patient.

Canine Synovial Sarcoma of the Stifle Joint with Pulmonary and Liver Metastases

2021 ◽  
Vol 38 ◽  
pp. 6-12
Author(s):  
R.J. Samson ◽  
F.H. Mpagike ◽  
A.K. Felix ◽  
A.B. Matondo ◽  
M. Makungu
Keyword(s):  
Soft Tissue ◽  
Lung Metastases ◽  
Synovial Cell ◽  
Proximal Region ◽  
Radiographic Examination ◽  
Tissue Samples ◽  
Stifle Joint ◽  
Mongrel Dog ◽  
Biopsy Examination ◽  
The Right

A seven-year-old female mongrel dog was presented at the Sokoine University of Agriculture Teaching Animal Hospital for second opinion regarding a progressive swelling of the right hind limb of two months duration. Clinical examination revealed a loss of body condition, tachypnea and tachycardia, a painful immobile solid mass of 20 cm x 14 cm x 10 cm located on the right stifle joint, leucocytosis, and anaemia. Radiographic examination of the joint revealed marked soft tissue swelling with amorphous areas of mineralization and complete destruction of the proximal tibia. Smooth and solid periosteal reaction was seen around the tibia and fibula with a Codman’s triangle. Multiple nodules and a mass with soft tissue opacity were seen in the lung fields. Post-mortem examination revealed separation of tibia and fibula, softening of the proximal parts of the tibia, and complete integration of the proximal region of the two bones and articular tissues into the surrounding muscular tissues. Multifocal nodular lesions of variable sizes were mostly found in the lungs and partly in the liver. Histologically, predominantly oval and round cells with variable nuclear sizes and moderate mitoses were observed in tissue samples from the joint, lungs and the liver although some parts of the lung metastases showed both round and spindle shaped tumor cells. Clinical profile is suggestive of aggressive biphasic (spindle and epithelial) type of synovial cell sarcoma with lung and liver metastasis. Early radiographic and biopsy examination of persistent musculoskeletal nodules is recommended for early diagnosis and interventions.

scholarly journals Sialolipoma of the sublingual salivary gland in a dog – first report

2019 ◽  
Vol 56 (1) ◽  
pp. e149060
Author(s):  
Andressa Gianotti Campos ◽  
Geni Patricio ◽  
Patrícia Ferreira de Castro ◽  
Luciane Kanayama ◽  
Alessandra Loureiro Morales dos Santos ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Soft Tissue ◽  
Fibrous Capsule ◽  
Resected Specimen ◽  
Histopathological Analysis ◽  
First Report ◽  
First Case ◽  
Large Numbers ◽  
Soft Tissue Swelling ◽  
The Right

This report describes a 14-year-old Pit Bull dog presenting with a soft tissue swelling of 3-month progression in the right sublingual region. Histopathological analysis of the surgically resected specimen revealed large numbers of mature adipocytes and islets consisting of mucin-containing atrophic acini and dilated ducts surrounded by a thin fibrous capsule. Findings were consistent with sialolipoma of the sublingual salivary gland. To the authors’ knowledge, this is the first case of sialolipoma affecting the sublingual salivary gland in dogs.

scholarly journals Carpometacarpal Dislocation with Third Metacarpal Fracture

2021 ◽  
Vol 5 (4) ◽  
pp. 488-490
Author(s):  
Colin Jorgensen ◽  
Steve Christos
Keyword(s):  
Soft Tissue ◽  
Plain Radiograph ◽  
Wrist Injuries ◽  
Rare Injury ◽  
Case Presentation ◽  
Metacarpal Fractures ◽  
Soft Tissue Swelling ◽  
Force Impact ◽  
The Right ◽  
Anterior Posterior

Case Presentation: A 17-year-old male presented to the emergency department (ED) due to trauma to the right hand and wrist after punching a locker at school. He had significant soft tissue swelling. Radiographs demonstrated intra-articular metacarpal fractures with associated carpometacarpal dislocations. The dislocation was reduced bedside in the ED and ultimately underwent closed reduction surgical management with orthopedic surgery. Discussion: Metacarpal fractures result from high-force impact injuries and account for 30-40% of all hand injuries. The most common sites of second through fifth metacarpal fractures are at the neck and the shaft, with the majority involving the fifth metacarpal neck (commonly coined “boxer’s fractures”). Carpometacarpal (CMC) dislocations are a rare injury associated with high-force impact trauma to the wrist. These injuries account for as little as 1% of all acute hand and wrist injuries. Carpometacarpal dislocations are often difficult to diagnose on physical examination due to significant soft tissue swelling, and they can easily be missed on anterior-posterior views of the hand. Lateral and oblique plain radiograph views are essential in the diagnosis as they are more likely to show dislocations. Despite appropriate plain radiographic views, subtle CMC dislocations may be difficult to discern dependent on the level of dislocation or subluxation and overlapping of joints. These injuries are rare due to otherwise highly stable ligamentous and muscular attachments within the wrist. Because of these attachments, dislocations are often associated with concomitant metacarpal fractures.

scholarly journals Laryngeal gout mimicking chondrosarcoma with concurrent longus colli tendinitis

2019 ◽  
Vol 12 (10) ◽  
pp. e231070
Author(s):  
Si Ying Chrisanda Lee ◽  
Yijin Jereme Gan ◽  
Julian Park Nam Goh ◽  
Yong Howe Ho ◽  
Ming Yann Lim
Keyword(s):  
Ct Scan ◽  
Thyroid Cartilage ◽  
Open Biopsy ◽  
Mri Scan ◽  
Ct Guided ◽  
Standardised Uptake Value ◽  
Positron Emission ◽  
Longus Colli ◽  
Ct Guided Biopsy ◽  
The Right

A 42-year-old man with multiple comorbidities, including gout, presented to the emergency department with severe odynophagia for 4 days with intermittent dysphagia for 1–2 months. A CT scan of the neck showed right longus colli tendinitis and partially calcified excrescences from the right thyroid cartilage which raised suspicion of a cartilaginous tumour. He underwent an MRI scan of the neck to better evaluate the thyroid cartilage findings, which showed a heterogeneous mass suspicious for a chondroid tumour. He then underwent a positron-emission tomography-CT scan which showed a fluorodeoxyglucose-avid mass containing foci of calcification involving the right thyroid cartilage and adjacent strap muscle, with high standardised uptake value of 7.7. He subsequently underwent a CT-guided biopsy and an open biopsy of the right thyroid cartilage, and the results revealed gouty tophi. To our knowledge, this is the first reported case of laryngeal gout with longus coli tendinitis, both of which are rare conditions.

Soft Tissue Tumors of the Foot and Ankle

Foot & Ankle ◽  
1988 ◽  
Vol 9 (1) ◽  
pp. 19-27 ◽  
Author(s):  
Karen S. Seale ◽  
Thomas A. Lange ◽  
David Monson ◽  
Donald A. Hackbarth
Keyword(s):  
Soft Tissue ◽  
Malignant Tumors ◽  
Synovial Cell ◽  
Clear Cell Sarcoma ◽  
Soft Tissue Tumors ◽  
Foot And Ankle ◽  
Cell Sarcoma ◽  
Malignant Lesions ◽  
Diagnostic Modalities ◽  
Malignant Soft Tissue

Seven patients with malignant soft tissue tumors of the foot and ankle were retrospectively reviewed. Emphasis was placed on the value of various diagnostic modalities used preoperatively for staging and the adequacy of treatment rendered using current tumor surgery principles. The malignant tumors included synovial cell sarcoma (four), clear cell sarcoma (one), fibrosarcoma (one), and melanoma (one). Surgical management of the malignant lesions included intracapsular excision, marginal excision, wide excision, and radical amputation.

scholarly journals Clinical and radiographic presentation of pelvic sarcoma in children

SICOT-J ◽  
2018 ◽  
Vol 4 ◽  
pp. 44 ◽  
Author(s):  
Muayad Kadhim ◽  
Nariman Abol Oyoun ◽  
Richard B. Womer ◽  
John P. Dormans
Keyword(s):  
Soft Tissue ◽  
Ewing Sarcoma ◽  
Epithelioid Sarcoma ◽  
Synovial Cell ◽  
Lytic Lesion ◽  
Tumor Type ◽  
Tissue Mass ◽  
Undifferentiated Sarcoma ◽  
Cell Sarcoma ◽  
Synovial Cell Sarcoma

Introduction: Pelvic sarcomas may present with vague symptoms. The aim of this study was to examine the characteristics and clinical presentations of different types of pelvic sarcoma in children. Methods: This is a retrospective cohort study of patients up to 21 years of age with the diagnosis of pelvic sarcoma between January 2000 and June 2013. Data on demographics, tumor type and location, and clinical presentation were collected from the medical records. Results: A total of 59 patients [37 males (62.7%) and 22 females (37.3%)] were examined in this study. Mean age at presentation was 11.3 ± 5 years (range 0.8–21 years). Thirty-six patients had Ewing sarcoma (61%), 9 osteosarcoma (6.8%), 4 undifferentiated sarcoma (6.8%), 2 (3.4%) rhabdomyosarcoma, 2 synovial cell sarcoma, and one (1.7%) of each fibrosarcoma, dermatofibrosarcoma, fibromyxoid sarcoma, chondrosarcoma, chordoma, and epithelioid sarcoma. Pain at presentation was reported in 41 patients, 13 mass, 8 limping, and 5 neurologic symptoms. Most of the bony tumors were painful (77%), while most of the soft tissue tumors were painless (70%). Nine patients presented with constitutional symptoms. Most patients presented within 4–12 months from symptoms beginning. Twenty-one patients (35.6%) presented with metastases (14 Ewing sarcoma, 6 osteosarcoma, and 1 synovial cell sarcoma). Pelvic radiographs showed lytic lesion in 11 patients, 4 sclerotic lesions, 6 mixed lesion, 6 had only soft tissue mass, 1 radiograph showed osteopenia, and 2 radiographs were reported normal. Conclusion: Ewing sarcoma was the most common pelvic sarcoma tumor in children. In most cases, pelvic sarcoma in children presented with pain mimicking other benign conditions. Some patients presented with metastatic disease with no prognostic clinical or radiographical signs or symptoms. Pelvic sarcoma should be considered a differential diagnosis as part of children work up.

scholarly journals Common swelling of the dorsal thoracic wall brings an unexpected finding: elastofibroma dorsi

2020 ◽  
Vol 90 (1) ◽  
Author(s):  
Sotirios Kotoulas ◽  
Konstantinos Grapatsas ◽  
Charalampos Georgiou ◽  
Zoi Tsilogianni ◽  
Vasileios Leivaditis ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Excisional Biopsy ◽  
Radical Resection ◽  
Thoracic Wall ◽  
Diagnostic Tools ◽  
Unexpected Finding ◽  
Soft Tissue Swelling ◽  
The Right ◽  
Slow Growing

Elastofibroma is a rare benign, soft-tissue slow-growing tumor seen predominantly in elderly females. We present such a case in a 46-year-old female. She presented with gradually increasing soft tissue swelling of 8×6 cm in the right inferior subscapular region. MRI showed a large intramuscular lesion with atypia. She underwent excisional biopsy and the histopathology and immunochemistry showed elastofibroma. We present this rare case to emphasize the important role of the diagnostic tools. A definitive diagnosis helps to avoid unnecessary wide and radical resection.

Dermoid Inclusion Cyst Following Percutaneous Needle Fasciotomy: A Novel Complication

2019 ◽  
Vol 24 (01) ◽  
pp. 116-117 ◽  
Author(s):  
Jenny Reid ◽  
Jill Baker ◽  
Dominique Davidson
Keyword(s):  
Soft Tissue ◽  
Histological Analysis ◽  
Penetrating Trauma ◽  
Flexion Contracture ◽  
Inclusion Cyst ◽  
Unique Case ◽  
Right Hand ◽  
Soft Tissue Swelling ◽  
The Right ◽  
Little Finger

We present the case of a fit and well 62-year-old male with Dupuytren's disease in the right hand who underwent percutaneous needle fasciotomy (PNF) for a moderate flexion contracture of the right little finger. 18 months later he developed a pain-free soft tissue swelling at the distal previous needling site. A fasciectomy procedure identified a cyst within the pre-tendinous cord, which was confirmed as a dermoid inclusion cyst on histological analysis. Dermoid inclusion cysts may occur in the hands at the site of penetrating trauma but we are unaware of any report of an inclusion cyst at the site of PNF surgery. We present this unique case of a dermoid inclusion cyst following percutaneous needle fasciotomy as a novel complication.

Evaluation of 99mTc-Label led Vitamin K4 as an Agent for Testicular Imaging

1991 ◽  
Vol 30 (01) ◽  
pp. 35-39 ◽  
Author(s):  
H. S. Durak ◽  
M. Kitapgi ◽  
B. E. Caner ◽  
R. Senekowitsch ◽  
M. T. Ercan
Keyword(s):  
Soft Tissue ◽  
Room Temperature ◽  
Normal Subjects ◽  
Left Testis ◽  
Wide Range ◽  
Activity Ratios ◽  
The Right ◽  
Radioactivity Levels

Vitamin K4 was labelled with 99mTc with an efficiency higher than 97%. The compound was stable up to 24 h at room temperature, and its biodistribution in NMRI mice indicated its in vivo stability. Blood radioactivity levels were high over a wide range. 10% of the injected activity remained in blood after 24 h. Excretion was mostly via kidneys. Only the liver and kidneys concentrated appreciable amounts of radioactivity. Testis/soft tissue ratios were 1.4 and 1.57 at 6 and 24 h, respectively. Testis/blood ratios were lower than 1. In vitro studies with mouse blood indicated that 33.9 ±9.6% of the radioactivity was associated with RBCs; it was washed out almost completely with saline. Protein binding was 28.7 ±6.3% as determined by TCA precipitation. Blood clearance of 99mTc-l<4 in normal subjects showed a slow decrease of radioactivity, reaching a plateau after 16 h at 20% of the injected activity. In scintigraphic images in men the testes could be well visualized. The right/left testis ratio was 1.08 ±0.13. Testis/soft tissue and testis/blood activity ratios were highest at 3 h. These ratios were higher than those obtained with pertechnetate at 20 min post injection.99mTc-l<4 appears to be a promising radiopharmaceutical for the scintigraphic visualization of testes.

Management of Haemophilia in Sweden

1976 ◽  
Vol 35 (03) ◽  
pp. 510-521 ◽  
Author(s):  
Inga Marie Nilsson
Keyword(s):  
Factor Viii ◽  
Total Population ◽  
Age Groups ◽  
Factor Ix ◽  
Haemophilia A ◽  
Severe Haemophilia ◽  
Haemophilia B ◽  
Human Fraction ◽  
Mild Haemophilia

SummaryThe incidence of living haemophiliacs in Sweden (total population 8.1 millions) is about 1:15,000 males and about 1:30,000 of the entire population. The number of haemophiliacs born in Sweden in 5-year periods between 1931-1975 (June) has remained almost unchanged. The total number of haemophilia families in Sweden is 284 (77% haemophilia A, 23% haemophilia B) with altogether 557 (436 with A and 121 with B) living haemophiliacs. Of the haemophilia A patients 40 % have severe, 18 % moderate, and 42 % mild, haemophilia. The distribution of the haemophilia B patients is about the same. Inhibitors have been demonstrated in 8% of the patients with severe haemophilia A and in 10% of those with severe haemophilia B.There are 2 main Haemophilia Centres (Stockholm, Malmo) to which haemophiliacs from the whole of Sweden are admitted for diagnosis, follow-up and treatment for severe bleedings, joint defects and surgery. Minor bleedings are treated at local hospitals in cooperation with the Haemophilia Centres. The concentrates available for treatment in haemophilia A are human fraction 1-0 (AHF-Kabi), cryoprecipitate, Antihaemophilic Factor (Hyland 4) and Kryobulin (Immuno, Wien). AHF-Kabi is the most commonly used preparation. The concentrates available for treatment in haemophilia B are Preconativ (Kabi) and Prothromplex (Immuno). Sufficient amounts of concentrates are available. In Sweden 3.2 million units of factor VIII and 1.0 million units of factor IX are given per year. Treatment is free of charge.Only 5 patients receive domiciliary treatment, but since 1958 we in Sweden have practised prophylactic treatment of boys (4–18 years old) with severe haemophilia A. At about 5-10 days interval they receive AHF in amounts sufficient to raise the AHF level to 40–50%. This regimen has reduced severe haemophilia to moderate. The joint score is identical with that found in moderate haemophilia in the same age groups. For treatment of patients with haemophilia A and haemophilia B complicated by inhibitors we have used a large dose of antigen (factor VIII or factor IX) combined with cyclophosphamide. In most cases this treatment produced satisfactory haemostasis for 5 to 30 days and prevented the secondary antibody rise.

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