Synchronous Multifocal Osteosarcoma: Case Report and Literature Review

Background. Multifocal osteosarcoma is usually described as the occurrence of the tumour at two or more sites in a patient without pulmonary metastases and may be synchronous or metachronous. Case report. A previously well 21-year old male, who presented with a swollen, painful right knee with no history of trauma, was found to have a high-grade osteosarcoma of the distal tibia and proximal femur. He underwent resection and prosthetic replacement of the distal femur and proximal tibia and remains well 19 months after diagnosis. Discussion. Multifocal osteosarcoma is a rare condition with a poor prognosis. There is debate about whether it represents multiple primary tumours or metastatic disease.

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Bilateral Congenital Humeroradial Synostostis Presenting with Bilateral Proximal Radius Fractures: A Case Report

Case Reports in Orthopedic Research ◽

10.1159/000512183 ◽

2021 ◽

pp. 29-32

Author(s):

Elsiddig E. Mahmoud

Keyword(s):

Case Report ◽

Elbow Joint ◽

Parental Education ◽

Functional Disability ◽

Congenital Abnormalities ◽

Rare Condition ◽

Radius Fractures ◽

Proximal Radius ◽

History Of ◽

Uncommon Condition

Congenital bilateral humeroradial synostosis (HRS) is a rare condition. It is generally divided into 2 categories. In the first group, which is mainly sporadic, additional upper limb hypoplasia typically coexists. In the second group, which is classically familial, HRS is commonly an isolated upper extremity anomaly. HRS can lead to variable degrees of functional disability. The clinical case reported here illustrates a possibly avoidable presentation of this uncommon condition. In this case report, we present a 6-week-old male who presented with bilateral radius fractures. Radiography revealed congenital HRS at both elbows. No other associated congenital abnormalities were detected, and there was no family history of similar conditions in any first-degree relatives. In cases of congenital HRS, movement at the elbow joint is not possible. Parents who are unaware of this information might try to straighten their infant’s elbows, which in turn may result in fractures of the proximal radius. Hence, early diagnosis and proper parental education could prevent fractures as a sequela of HRS.

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Rupture of sinus of Valsalva aneurysm: case report and review of contemporary literature

Perfusion ◽

10.1177/0267659120966915 ◽

2020 ◽

pp. 026765912096691

Author(s):

Jean-Luc Duval ◽

Richard AE Ramsingh ◽

Natasha C Rahaman ◽

Risshi D Rampersad ◽

Gianni D Angelini ◽

...

Keyword(s):

Case Report ◽

Cardiac Failure ◽

Congenital Heart ◽

Contemporary Literature ◽

Rare Condition ◽

Aneurysm Rupture ◽

Sinus Of Valsalva ◽

Sinus Of Valsalva Aneurysm ◽

History Of ◽

High Index Of Suspicion

Sinus of Valsalva aneurysm rupture is a rare condition with a great potential for morbidity and mortality if not promptly diagnosed and managed. We present an unusual non-infected sinus of Valsalva aneurysm rupture in a 47-year-old female. This case report, a likely presentation of a late congenital heart defect, highlights the need for a high index of suspicion in a patient with atypical history of congestive cardiac failure.

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Treatment of an open distal tibia fracture with segmental bone loss in combination with a closed proximal tibia fracture: a case report

Archives of Orthopaedic and Trauma Surgery ◽

10.1007/s00402-012-1523-6 ◽

2012 ◽

Vol 132 (8) ◽

pp. 1121-1124 ◽

Cited By ~ 1

Author(s):

Jin Park ◽

Kyu Hyun Yang

Keyword(s):

Case Report ◽

Bone Loss ◽

Proximal Tibia ◽

Distal Tibia ◽

Tibia Fracture ◽

Proximal Tibia Fracture ◽

Distal Tibia Fracture ◽

Segmental Bone

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Thyrotoxic periodic paralysis in new-onset hyperthyroidism – a case report and review of the literature

Revista de Ciências Médicas e Biológicas ◽

10.9771/cmbio.v12i4.9207 ◽

2014 ◽

Vol 12 (4) ◽

pp. 531

Author(s):

Joaquim Custódio da Silva Junior ◽

Helton Estrela Ramos

Keyword(s):

Case Report ◽

Previous History ◽

Rare Condition ◽

Periodic Paralysis ◽

Emergency Physicians ◽

Review Of The Literature ◽

Font Size ◽

Thyrotoxic Periodic Paralysis ◽

History Of ◽

New Onset

Thyrotoxic periodic paralysis (TPP) is a rare condition related to hyperthyroidism, with specific clinical and physiopathological features. In this article, we discuss a case report of a patient that develops TPP with no previous history of thyroid illness, highlighting semiological characteristics that can help Emergency physicians to suspect of this condition. Subsequently, we review the recent articles about TPP, with focus in the molecular basis of ion channelopathies and predisposing factors, and discuss the therapeutic approach at acute phase of TPP and prevention of crisis recurrence.

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Tolosa-Hunt: Case Report

10.5327/1516-3180.390 ◽

2021 ◽

Author(s):

Lília Tereza Diniz Nunes ◽

Flávia S. Silva ◽

Karyme G. Aota ◽

Maria Beatriz Miranda S. B. de Assis ◽

João Fellipe B. Bento ◽

...

Keyword(s):

Case Report ◽

Cavernous Sinus ◽

Clinical Care ◽

Cranial Nerves ◽

Rare Condition ◽

Unknown Etiology ◽

Specific Diagnosis ◽

Hunt Syndrome ◽

Diagnosis By Exclusion ◽

History Of

Context: Tolosa-Hunt Syndrome (STH) is a rare condition with unknown etiology, it affects both genders equally. It is manifested by inflammation of the cavernous sinus and involvement of some cranial nerves pairs. Case report: MSR, 39 years, male, diver in the mining zone, history of recurrent otitis with acute pain and gradual hearing loss that progressed. He was admitted to the General Hospital of Palmas with symptoms of retrorbital headache. After physical exams it was found an ophthalmoplegia with right amaurosis and ipsilateral pain. The neurological examination showed a right eye with loss of photomotor reflex and presence of consensual reflex and eyelid ptosis. After 38 days in hospital, a probable septic thrombosis of the cavernous sinus was found, antibiotic and corticosteroids therapy was initiated. The patient also reports significant improvement in headache and partially in vision, he is currently hospitalized with clinical care and antibiotic therapy, awaiting results of the image examination report. Conclusions: Painful ophthalmoplegia in most cases is not diagnosed as STH. The differential diagnosis for this pathology is most often through brain magnetic ressonance and the ICHD-3 beta diagnostic criteria, STH should be suspected, but it is still necessary to close the diagnosis by exclusion, due to the lack of a specific diagnosis.

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Radiation-Induced Stromal Sarcoma of Breast: A Case Report and Literature Review

International Journal of Cancer Management ◽

10.5812/ijcm.107295 ◽

2021 ◽

Vol In Press (In Press) ◽

Author(s):

Amir Shahram Yousefi Kashi ◽

Farzad Taghizadeh-Hesary

Keyword(s):

Case Report ◽

Rare Condition ◽

Standard Chemotherapy ◽

Case Presentation ◽

Stromal Sarcoma ◽

Local Progression ◽

New Knowledge ◽

History Of ◽

Radiation Induced ◽

Axillary Mass

Introduction: Post-irradiation mammary stromal sarcoma (MSS) is a rare condition, and it is worth learning new knowledge from each case. Case Presentation: We present the case report of a 59-year-old female with a medical history of breast cancer, who presented with an axillary mass on the same side. The patient was further evaluated and finally diagnosed with MSS with chondroid differentiation. Thereafter, she underwent neoadjuvant chemotherapy to facilitate the surgical resection of the tumor. However, she experienced local progression and lung metastasis during chemotherapy. Conclusions: MSS with chondroid differentiation was resistant to the standard chemotherapy regimens of sarcoma. Radiotherapy is a potential choice in the case of chemoresistant MSS. Further trials may reveal this notion.

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Dyke-Davidoff-Masson Syndrome: A case Report in a patient presenting with drug-resistant epilepsy and pseudoseizures

10.5327/1516-3180.245 ◽

2021 ◽

Author(s):

Pedro Schmidt dos Reis Matos Figueiredo ◽

Thiago Oliveira Chaves

Keyword(s):

Case Report ◽

Cognitive Dysfunction ◽

Brain Magnetic Resonance Imaging ◽

Rare Condition ◽

Signs And Symptoms ◽

Drug Resistant ◽

Cerebral Hemiatrophy ◽

History Of ◽

Magnetic Resonance Imaging Mri ◽

Drug Resistant Epilepsy

Context: Dyke-Davidoff-Masson (DDM) syndrome is a rare neurological condition, first described in 1933. Characteristics include cerebral hemiatrophy, contralateral hemiparesis, seizures, and cognitive dysfunction, combined into different degrees and patterns. Brain magnetic resonance imaging (MRI) is used to perform diagnosis throughout its specific findings. Case Report: A eighteen-year-old female presented to our service with a history of cognitive dysfunction and seizures since early childhood, which persistence even with adequate use of antiepileptic drugs. During Investigation were found signs and symptoms compatible with DDM syndrome, and evidence of pseudoseizures captured in a video electroencephalography monitoring. Conclusion: DDM syndrome is a rare condition that must be part of differential diagnosis in patients with seizures and cerebral hemiatrophy. Management is based on adequate control of seizures and other comorbidities.

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Unilateral Multiple Extramedullary Plasmacytoma of the Choroid and Conjunctiva: A Case Report

Journal of VitreoRetinal Diseases ◽

10.1177/2474126419893175 ◽

2019 ◽

Vol 4 (2) ◽

pp. 152-156

Author(s):

Shymaa Mohamed ◽

Truman Silvasi ◽

Anthony Kubat ◽

Thomas Aaberg

Keyword(s):

Multiple Myeloma ◽

Case Report ◽

Radiation Dose ◽

Poor Prognosis ◽

Clinical Manifestations ◽

Excisional Biopsy ◽

Extramedullary Plasmacytoma ◽

Eye Pain ◽

History Of ◽

Conjunctival Nodule

Purpose: We report a case of multiple extramedullary plasmacytoma (EMP) of the choroid and conjunctiva as a sign of multiple myeloma (MM) relapse. Methods: An observational case report with clinicopathologic correlation is presented. Results: A 45-year-old man with a 2.5-year history of MM presented with left eye pain. Examination revealed a conjunctival nodule and choroidal infiltrate in the left eye. Excisional biopsy demonstrated plasmacytoma of the conjunctiva and choroid. Despite radiotherapy and chemotherapy, multiple EMP recurred and the patient died 8 months after initial presentation. Conclusions: Multiple EMP of the choroid and conjunctiva has a poor prognosis and can present as a sign of MM relapse. Our imaging demonstrates the clinical manifestations of this tumor and can aid future diagnoses. Our radiation dose (20 Gy) was inadequate, which is an important reportable factor for future patients.

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Coexistence of Ectopic Posterior Pituitary and Sellar/Suprasellar Arachnoid Cyst: A Case Report

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405616666200530210847 ◽

2020 ◽

Vol 16 (8) ◽

pp. 1055-1057

Author(s):

Suzan Saylisoy ◽

Goknur Yorulmaz

Keyword(s):

Case Report ◽

Rare Condition ◽

Optic Chiasm ◽

Magnetic Resonance Images ◽

Bright Spot ◽

Posterior Pituitary ◽

First Case ◽

History Of ◽

Diaphragma Sellae ◽

Ectopic Posterior Pituitary

Background: The ectopic posterior pituitary (EPP) is a rare condition characterized by the ectopic location of the posterior pituitary lobe associated with varying degrees of stalk anomalies. The arachnoid cysts (AC) are benign lesions of the arachnoid, which account for 1% of all intracranial space-occupying lesions. Sellar/suprasellar ACs account for approximately 1% of all ACs. This is the first case of coexistence EPP with sellar/suprasellar AC. Case Report: A 67-year-old woman presented with 6 months history of fatigue. Her medical history was positive for irregular menstruation. Her endocrine examinations indicated low free thyroxine level with low TSH level, low oestradiol with low gonadotrophin level, slightly elevated prolactin level. Her Insulin-like growth factor-1 was below the normal levels. Dynamic contrast hypophysis MRI revealed a sellar cystic lesion with a dimension of 18 × 14 × 14 mm, extending from the suprasellar cistern, traversing the diaphragma sellae and reaching the level of the floor of the 3rd ventricle, consistent with sellar/suprasellar AC. There was no wall enhancement. The optic chiasm was compressed. The precontrast T1-weighted magnetic resonance images did not demonstrate the characteristic bright spot of posterior pituitary within the sella, which was higher in position, in the region of the median eminence. The pituitary stalk was not present. Conclusion: Although speculative, we have a hypothesis to explain how the EPP and sellar/- suprasellar AC coexist in this patient. Due to the absence of stalk, CSF may enter the sella tursica from the central aperture of the diaphragma sellae through which normally the stalk passes.

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