A New Safer and More Effective Triphenylethylene Antiestrogen (SS1020) for the Treatment and Prevention of Breast Cancer.

2009 ◽  
Author(s):  
S. Shibutani ◽  
Y. Okamoto ◽  
N. Suzuki ◽  
X. Liu ◽  
H. Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Treatment And Prevention ◽  
Prevention Of Breast Cancer

scholarly journals Advances in Rodent Models for Breast Cancer Formation, Progression, and Therapeutic Testing

2021 ◽  
Vol 11 ◽  
Author(s):  
Chong Liu ◽  
Pei Wu ◽  
Ailin Zhang ◽  
Xiaoyun Mao
Keyword(s):  
Breast Cancer ◽  
Cancer Progression ◽  
Rodent Model ◽  
Rodent Models ◽  
Clinical Therapeutics ◽  
Advantages And Disadvantages ◽  
Treatment And Prevention ◽  
Mechanism Of Carcinogenesis ◽  
Prevention Of Breast Cancer ◽  
Selection Of

Breast cancer is a highly complicated disease. Advancement in the treatment and prevention of breast cancer lies in elucidation of the mechanism of carcinogenesis and progression. Rodent models of breast cancer have developed into premier tools for investigating the mechanisms and genetic pathways in breast cancer progression and metastasis and for developing and evaluating clinical therapeutics. Every rodent model has advantages and disadvantages, and the selection of appropriate rodent models with which to investigate breast cancer is a key decision in research. Design of a suitable rodent model for a specific research purpose is based on the integration of the advantages and disadvantages of different models. Our purpose in writing this review is to elaborate on various rodent models for breast cancer formation, progression, and therapeutic testing.

scholarly journals Beneficial Oxidative Stress-Related trans-Resveratrol Effects in the Treatment and Prevention of Breast Cancer

2021 ◽  
Vol 11 (22) ◽  
pp. 11041
Author(s):  
Alessandra Quarta ◽  
Antonio Gaballo ◽  
Biswajita Pradhan ◽  
Srimanta Patra ◽  
Mrutyunjay Jena ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Biological Activities ◽  
Tumor Development ◽  
Primary Sources ◽  
Beneficial Effects ◽  
Chemotherapy Drugs ◽  
Treatment And Prevention ◽  
The Impact ◽  
Prevention Of Breast Cancer

Resveratrol is one of the most investigated polyphenols for its multiple biological activities and many beneficial effects. These are mainly related to its ability to scavenge free radicals and reduce oxidative stress. Resveratrol has also been shown to have the ability to stimulate the production of antioxidant enzymes, which interact with numerous signaling pathways involved in tumor development, and to possess side effects associated with the use of chemotherapy drugs. In this review article we summarized the main discoveries about the impact resveratrol can have in helping to prevent, as well as adjuvant treating, breast cancer. A brief overview of the primary sources of resveratrol as well as some approaches for improving its bioavailability have been also discussed.

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