Crosstalk between Insulin/Insulin-like Growth Factor-1 Receptors and G Protein-Coupled Receptor Signaling Systems: A Novel Target for the Antidiabetic Drug Metformin in Pancreatic Cancer: Fig. 1.

Antidiabetic Drug ◽

Signaling Systems ◽

Novel Target ◽

Metformin Disrupts Crosstalk between G Protein–Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth

Cancer Research ◽

10.1158/0008-5472.can-09-0418 ◽

2009 ◽

Vol 69 (16) ◽

pp. 6539-6545 ◽

Cited By ~ 208

Author(s):

Krisztina Kisfalvi ◽

Guido Eibl ◽

James Sinnett-Smith ◽

Enrique Rozengurt

Keyword(s):

Pancreatic Cancer ◽

Insulin Receptor ◽

G Protein ◽

Cancer Growth ◽

Receptor Signaling ◽

Signaling Systems ◽

Insulin Receptor Signaling ◽

Crosstalk Between Insulin Receptor and G Protein-Coupled Receptor Signaling Systems Leads to Ca2+ Oscillations in Pancreatic Cancer PANC-1 Cells

Gastroenterology ◽

10.1016/s0016-5085(11)61993-8 ◽

2011 ◽

Vol 140 (5) ◽

pp. S-483

Author(s):

Steven H. Young ◽

Enrique Rozengurt

Keyword(s):

Pancreatic Cancer ◽

Insulin Receptor ◽

G Protein ◽

Receptor Signaling ◽

Signaling Systems ◽

M1968 Metformin Disrupts Crosstalk Between G Protein-Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth

Gastroenterology ◽

10.1016/s0016-5085(10)62078-1 ◽

2010 ◽

Vol 138 (5) ◽

pp. S-449

Author(s):

Krisztina Kisfalvi ◽

Steven H. Young ◽

James Sinnett-Smith ◽

Guido Eibl ◽

Enrique Rozengurt

Keyword(s):

Pancreatic Cancer ◽

Insulin Receptor ◽

G Protein ◽

Cancer Growth ◽

Receptor Signaling ◽

Signaling Systems ◽

Insulin Receptor Signaling ◽

Crosstalk between insulin receptor and G protein-coupled receptor signaling systems leads to Ca2+ oscillations in pancreatic cancer PANC-1 cells

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2010.09.036 ◽

2010 ◽

Vol 401 (1) ◽

pp. 154-158 ◽

Cited By ~ 16

Author(s):

Steven H. Young ◽

Enrique Rozengurt

Keyword(s):

Pancreatic Cancer ◽

Insulin Receptor ◽

G Protein ◽

Receptor Signaling ◽

Signaling Systems ◽

Abstract 1790: Investigation of oncogenic G-protein coupled receptor signaling pathways inKrasdependent pancreatic cancer cell lines

10.1158/1538-7445.sabcs18-1790 ◽

2019 ◽

Author(s):

Ozhan Ocal ◽

Raymond MacDonald ◽

Rolf A. Brekken ◽

Thomas Wilkie

Keyword(s):

Pancreatic Cancer ◽

Signaling Pathways ◽

G Protein ◽

Cell Lines ◽

Cancer Cell ◽

Pancreatic Cancer Cell ◽

Cancer Cell Lines ◽

Receptor Signaling ◽

G protein-coupled receptor signaling in human ductal pancreatic cancer cells: Neurotensin responsiveness and mitogenic stimulation

Journal of Cellular Physiology ◽

10.1002/1097-4652(200101)186:1<53::aid-jcp1004>3.0.co;2-q ◽

2000 ◽

Vol 186 (1) ◽

pp. 53-64 ◽

Cited By ~ 53

Author(s):

Nova M. Ryder ◽

Sushovan Guha ◽

Oscar J. Hines ◽

Howard A. Reber ◽

Enrique Rozengurt

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

G Protein ◽

Receptor Signaling ◽

Mitogenic Stimulation ◽

Pancreatic Cancer Cells ◽

Ductal Pancreatic Cancer ◽

Investigation of oncogenic G‐protein coupled receptor signaling pathways in Kras dependent pancreatic cancer cell lines

The FASEB Journal ◽

10.1096/fasebj.2019.33.1_supplement.647.29 ◽

2019 ◽

Vol 33 (S1) ◽

Author(s):

Ozhan Ocal ◽

Raymond MacDonald ◽

Rolf A. Brekken ◽

Thomas Wilkie

Keyword(s):

Pancreatic Cancer ◽

Signaling Pathways ◽

G Protein ◽

Cell Lines ◽

Cancer Cell ◽

Pancreatic Cancer Cell ◽

Cancer Cell Lines ◽

Receptor Signaling ◽

Abstract 1790: Investigation of oncogenic G-protein coupled receptor signaling pathways inKrasdependent pancreatic cancer cell lines

10.1158/1538-7445.am2019-1790 ◽

2019 ◽

Author(s):

Ozhan Ocal ◽

Raymond MacDonald ◽

Rolf A. Brekken ◽

Thomas Wilkie

Keyword(s):

Pancreatic Cancer ◽

Signaling Pathways ◽

G Protein ◽

Cell Lines ◽

Cancer Cell ◽

Pancreatic Cancer Cell ◽

Cancer Cell Lines ◽

Receptor Signaling ◽

Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1118359109 ◽

2012 ◽

Vol 109 (18) ◽

pp. 7055-7060 ◽

Cited By ~ 65

Author(s):

H. Zheng ◽

C. Worrall ◽

H. Shen ◽

T. Issad ◽

S. Seregard ◽

...

Keyword(s):

Growth Factor ◽

G Protein ◽

Insulin Like Growth Factor ◽

Receptor Kinases ◽

Antimicrobial peptide derived from insulin‐like growth factor‐binding protein 5 activates mast cells via Mas‐related G protein‐coupled receptor X2

Allergy ◽

10.1111/all.13975 ◽

2019 ◽

Vol 75 (1) ◽

pp. 203-207 ◽

Cited By ~ 2

Author(s):

François Niyonsaba ◽

Pu Song ◽

Hainan Yue ◽

Nutda Sutthammikorn ◽

Yoshie Umehara ◽

...

Keyword(s):

Growth Factor ◽

Mast Cells ◽

Antimicrobial Peptide ◽

G Protein ◽

Binding Protein ◽

Insulin Like Growth Factor ◽

Factor Binding ◽