Abstract 4813: Comparative activity profiling of tyrosine kinase inhibitors (TKIs) against exon 20 insertions and the wild-type form of epidermal growth factor receptor (EGFR)

Mapping Intimacies ◽

10.1158/1538-7445.am2019-4813 ◽

2019 ◽

Author(s):

Richard A. Ward ◽

Ambra Bianco ◽

Nicola Colclough ◽

Darren Cross ◽

Emanuela M. Cuomo ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Wild Type ◽

Type Form ◽

Epidermal Growth ◽

Exon 20 ◽

Wild Type Form ◽

Comparative Activity

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Abstract 4813: Comparative activity profiling of tyrosine kinase inhibitors (TKIs) against exon 20 insertions and the wild-type form of epidermal growth factor receptor (EGFR)

10.1158/1538-7445.sabcs18-4813 ◽

2019 ◽

Author(s):

Richard A. Ward ◽

Ambra Bianco ◽

Nicola Colclough ◽

Darren Cross ◽

Emanuela M. Cuomo ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Wild Type ◽

Type Form ◽

Epidermal Growth ◽

Exon 20 ◽

Wild Type Form ◽

Comparative Activity

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The Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancer Harboring Wild-type Epidermal Growth Factor Receptor

American Journal of Clinical Oncology ◽

10.1097/coc.0000000000000179 ◽

2017 ◽

Vol 40 (4) ◽

pp. 362-369 ◽

Author(s):

Zhixin Sheng ◽

Yanxia Zhang

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Wild Type ◽

Small Cell Lung ◽

Epidermal Growth

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Epidermal growth factor receptor (EGFR) exon 20 mutations in non-small-cell lung cancer and resistance to EGFR-tyrosine kinase inhibitors

Investigational New Drugs ◽

10.1007/s10637-014-0146-x ◽

2014 ◽

Vol 32 (6) ◽

pp. 1311-1315 ◽

Author(s):

Hyun Sun Woo ◽

Hee Kyung Ahn ◽

Ha Yeon Lee ◽

Inkeun Park ◽

Young Saing Kim ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

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Is there a role for epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor wild-type non-small cell lung cancer?

World Journal of Clinical Oncology ◽

10.5306/wjco.v6.i4.45 ◽

2015 ◽

Vol 6 (4) ◽

pp. 45 ◽

Author(s):

Edurne Arriola ◽

Álvaro Taus ◽

David Casadevall

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Wild Type ◽

Small Cell Lung ◽

Epidermal Growth

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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With EGFR Wild-Type Lung Cancer: When There Is a Target, There Is a Targeted Drug

Journal of Clinical Oncology ◽

10.1200/jco.2014.57.5449 ◽

2015 ◽

Vol 33 (5) ◽

pp. 523-524 ◽

Author(s):

Fei Zhou ◽

Xiaoxia Chen ◽

Caicun Zhou

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Wild Type ◽

Epidermal Growth ◽

Targeted Drug ◽

Receptor Tyrosine Kinase Inhibitors

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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors vs Conventional Chemotherapy in Non–Small Cell Lung Cancer Harboring Wild-Type Epidermal Growth Factor Receptor

JAMA ◽

10.1001/jama.2014.3314 ◽

2014 ◽

Vol 311 (14) ◽

pp. 1430 ◽

Author(s):

June-Koo Lee ◽

Seokyung Hahn ◽

Dong-Wan Kim ◽

Koung Jin Suh ◽

Bhumsuk Keam ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Wild Type ◽

Small Cell Lung ◽

Conventional Chemotherapy ◽

Epidermal Growth

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Clinical impact of amphiregulin expression in patients with epidermal growth factor receptor (EGFR) wild-type nonsmall cell lung cancer treated with EGFR-tyrosine kinase inhibitors

Cancer ◽

10.1002/cncr.25560 ◽

2010 ◽

Vol 117 (1) ◽

pp. 143-151 ◽

Author(s):

Myung Hee Chang ◽

Hee Kyung Ahn ◽

Jeeyun Lee ◽

Chan-Kwon Jung ◽

Yoon-La Choi ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Nonsmall Cell Lung Cancer ◽

Clinical Impact ◽

Wild Type ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors from the Natural Origin: A Recent Perspective

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520615666150312100259 ◽

2015 ◽

Vol 15 (8) ◽

pp. 988-1011 ◽

Author(s):

Harun Patel ◽

Rajesh Rane ◽

Neeta Thapliyal ◽

Mahesh Palkar ◽

Mahamadhanif Shaikh ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Natural Origin ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth

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Sensitivity of epidermal growth factor receptor and ErbB2 exon 20 insertion mutants to Hsp90 inhibition

British Journal of Cancer ◽

10.1038/sj.bjc.6603950 ◽

2007 ◽

Vol 97 (6) ◽

pp. 741-744 ◽

Author(s):

W Xu ◽

S Soga ◽

K Beebe ◽

M-J Lee ◽

Y S Kim ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Hsp90 Inhibition ◽

Epidermal Growth ◽

Exon 20 ◽

Insertion Mutants

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Clinical and molecular characteristics of epidermal growth factor receptor exon 20 insertion mutations in non-small-cell lung cancer

Clinical & Translational Oncology ◽

10.1007/s12094-021-02701-x ◽

2021 ◽

Author(s):

D. Geng ◽

Q. Guo ◽

S. Huang ◽

H. Zhang ◽

S. Guo ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Growth Factor Receptor ◽

Molecular Characteristics ◽

Small Cell Lung ◽

Epidermal Growth ◽

Exon 20 ◽

Insertion Mutations

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