Abstract B21: Circulating tumor cell by microfluidic magnetophoresis-based gene expression changes for monitoring of prognosis in advanced prostate cancer patient: A pilot study

2020 ◽  
Author(s):  
Jae-Seung Chung ◽  
Hyungseok Cho ◽  
Ki-Ho Han
Keyword(s):  
Gene Expression ◽  
Prostate Cancer ◽  
Pilot Study ◽  
Cancer Patient ◽  
Tumor Cell ◽  
Advanced Prostate Cancer ◽  
Prostate Cancer Patient ◽  
Circulating Tumor Cell

scholarly journals Biomarkers for Treatment Response in Advanced Prostate Cancer

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5723
Author(s):  
Samia Asif ◽  
Benjamin A. Teply
Keyword(s):  
Prostate Cancer ◽  
Tumor Cell ◽  
Advanced Prostate Cancer ◽  
Treatment Options ◽  
Predictive Biomarkers ◽  
Treatment Decision ◽  
Circulating Tumor Cell ◽  
Surface Expression ◽  
Circulating Tumor Dna ◽  
Cell Surface Expression

Multiple treatment options with different mechanisms of action are currently available for the management of metastatic prostate cancer. However, the optimal use of these therapies—specifically, the sequencing of therapies—is not well defined. In order to obtain the best clinical outcomes, patients need to be treated with the therapies that are most likely to provide benefit and avoid toxic therapies that are unlikely to be effective. Ideally, predictive biomarkers that allow for the selection of the therapies most likely to be of benefit would be employed for each treatment decision. In practice, biomarkers including tumor molecular sequencing, circulating tumor DNA, circulating tumor cell enumeration and androgen receptor characteristics, and tumor cell surface expression (PSMA), all may have a role in therapy selection. In this review, we define the established prognostic and predictive biomarkers for therapy in advanced prostate cancer and explore emerging biomarkers.

scholarly journals Endosomal gene expression: a new indicator for prostate cancer patient prognosis?

Oncotarget ◽  
2015 ◽  
Vol 6 (35) ◽  
pp. 37919-37929 ◽  
Author(s):  
Ian R.D. Johnson ◽  
Emma J. Parkinson-Lawrence ◽  
Helen Keegan ◽  
Cathy D. Spillane ◽  
Jacqui Barry-O’Crowley ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prostate Cancer ◽  
Cancer Patient ◽  
Prostate Cancer Patient ◽  
Patient Prognosis

scholarly journals Decline in Circulating Tumor Cell Count and Treatment Outcome in Advanced Prostate Cancer

2016 ◽  
Vol 70 (6) ◽  
pp. 985-992 ◽  
Author(s):  
David Lorente ◽  
David Olmos ◽  
Joaquin Mateo ◽  
Diletta Bianchini ◽  
George Seed ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Treatment Outcome ◽  
Tumor Cell ◽  
Cell Count ◽  
Advanced Prostate Cancer ◽  
Circulating Tumor Cell
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