Chronic Stress Effects on Adrenocortical Responsiveness in Young and Aged Rats

1973 ◽  
Vol 11 (1) ◽  
pp. 1-10 ◽  
Author(s):  
G.D. Riegle
2002 ◽  
Vol 74 (1) ◽  
pp. 181-186 ◽  
Author(s):  
Iraci Lucena S Torres ◽  
Andreia Buffon ◽  
Giovana Dantas ◽  
Cristina Ribas Fürstenau ◽  
Ana Elisa Böhmer ◽  
...  

2018 ◽  
Vol 90 ◽  
pp. 92-101 ◽  
Author(s):  
Hongxin Dong ◽  
Jack M. Keegan ◽  
Ellie Hong ◽  
Christopher Gallardo ◽  
Janitza Montalvo-Ortiz ◽  
...  

1988 ◽  
Vol 254 (5) ◽  
pp. E617-E624 ◽  
Author(s):  
M. R. Odio ◽  
A. Brodish

The effect of age on the capacity of an organism to mobilize glucose and free fatty acids during stress and to adapt these responses from an acute to a chronic stress situation is not known. The purpose of this study was to determine whether aging impaired the capacity to 1) raise glucose and free fatty acid levels and suppress insulin release in acute stress situations and 2) develop adaptation of these responses to exposure to chronic stress. Our results indicate that 6-mo-old rats (young) trained to escape electric shock (short-term modulation) showed greater acute stress-induced hyperglycemic, hypoinsulinemic, and lipolytic responses than untrained young rats. By contrast, in 22-mo-old rats (old), responses of trained and untrained animals were not different. In the chronic stress (long-term adaptation) experiments, it was found that 1) adaptation of stress-induced hyperglycemia occurred at a faster rate in young than in old animals; 2) in young but not in aged rats, a strong positive correlation was observed between adaptation of stress-induced hyperglycemia and hypoinsulinemia; and 3) in young rats, stress-induced lipolytic responses declined proportionately to the duration of chronic stress exposure, whereas by contrast in chronically stressed aged rats steady-state levels of free fatty acids were not raised during exposure to stress. Thus we conclude that 1) glucose intolerance may play a key role in the altered stress-induced metabolic responses of aged rats; 2) with age, there is a loss of plasticity in physiological adaptive response mechanisms associated with metabolic responses to stress.


2020 ◽  
Vol 87 (9) ◽  
pp. S58-S59
Author(s):  
Christoph Anacker ◽  
Victor Luna ◽  
Ryan Shores ◽  
Gregory Stevens ◽  
Rene Hen

1998 ◽  
Vol 61 (4) ◽  
pp. 405-412 ◽  
Author(s):  
Boris B. Gorzalka ◽  
Laura A. Hanson ◽  
Lori A. Brotto

2006 ◽  
Vol 1126 (1) ◽  
pp. 156-166 ◽  
Author(s):  
Rachel E. Bowman ◽  
Neil J. Maclusky ◽  
Samantha E. Diaz ◽  
Mark C. Zrull ◽  
Victoria N. Luine

2017 ◽  
Vol 24 (14) ◽  
pp. 1923-1928 ◽  
Author(s):  
Ashley M Geiger ◽  
Clemens Kirschbaum ◽  
Jutta M Wolf

Inconsistent associations between health and measures of subjective social status compared to one’s community suggest that how people define community may matter. This study broke down community into status among neighborhood and friends/family to assess the impact of each domain on chronic stress in individuals differing in socioeconomic status (18 employed and 18 unemployed individuals). The findings suggest that for ratings of subjective social status, the social and physical proximity of the reference group matters. Specifically, neighborhood status was affected by unemployment, while friends/family status was associated with perceived stress, emphasizing the importance of the comparison group in assessing subjective status.


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