Racial Differences in the Influence of the APOE Epsilon 4 Allele on Cognitive Decline in a Sample of Community-Dwelling Older Adults

Gerontology ◽  
2008 ◽  
Vol 55 (1) ◽  
pp. 32-40 ◽  
Author(s):  
Kathryn Sawyer ◽  
Natalie Sachs-Ericsson ◽  
Kristopher J. Preacher ◽  
Dan G. Blazer
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Racial Differences ◽  
Community Dwelling ◽  
Community Dwelling Older Adults

The Brief Odor Detection Test (B-ODT) for Very Early Diagnosis of Cognitive Decline: A Preliminary Study

2017 ◽  
Vol 18 (2) ◽  
pp. 197-210
Author(s):  
Dimitra Savvoulidou ◽  
Efthymia Totikidou ◽  
Chariklia Varvesiotou ◽  
Magda Iakovidou ◽  
Ourania Sfakianaki ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Cognitive Decline ◽  
Adult Population ◽  
Detection Threshold ◽  
Community Dwelling ◽  
Odor Detection ◽  
Olfactory Impairment ◽  
Older Adult Population ◽  
Community Dwelling Older Adults

Olfactory impairment in older adults is associated with cognitive decline. This study describes the development of a Brief Odor Detection Test (B-ODT), and its pilot administration in community-dwelling older adults. The study aimed at examining whether the test could differentiate older adults with very mild cognitive impairment from their cognitively healthy counterparts. The sample consisted of 34 older adults (22 women), aged from 65 to 87 years. Participants were divided into two groups according to their general cognitive functioning. Odor detection was measured via vanillin solutions at the following concentrations: 150 mg/L, 30 mg/L, 15 mg/L, 3 mg/L, and .03 mg/L. The first condition of the test involved a scale administration of vanillin solutions. The second condition examined the change in air odour and it required vanillin solution of 30 mg/L and a metric ruler of 30 cm. The examiner had to place the solution at a specific distance point from each nostril. Odour identification sensitivity was secondarily measured. The results showed statistically significant differences in odour detection threshold between the two groups. In the unirhinal testing, left nostril differences of the two groups were definite. Hence, the B-ODT seems a promising instrument for very early cognitive impairment screening in older adult population.

Exaggerated reaction to novelty as a predictor of incipient cognitive decline among community-dwelling older adults

2018 ◽  
Vol 40 (10) ◽  
pp. 987-999 ◽  
Author(s):  
Yana Suchy ◽  
Emilie I. Franchow ◽  
Madison A. Niermeyer ◽  
Rosemary E. Ziemnik ◽  
Paula G. Williams ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Community Dwelling ◽  
Community Dwelling Older Adults

scholarly journals Circulating Dkk1 and TRAIL Are Associated With Cognitive Decline in Community-Dwelling, Older Adults With Cognitive Concerns

2018 ◽  
Vol 73 (12) ◽  
pp. 1688-1694 ◽  
Author(s):  
Ryan D Ross ◽  
Raj C Shah ◽  
Sue Leurgans ◽  
Teodoro Bottiglieri ◽  
Robert S Wilson ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Community Dwelling ◽  
Community Dwelling Older Adults

scholarly journals The Relationship between Subjective Cognitive Decline and Health Literacy in Healthy Community-Dwelling Older Adults

Healthcare ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 567
Author(s):  
Akio Goda ◽  
Shin Murata ◽  
Hideki Nakano ◽  
Koji Nonaka ◽  
Hiroaki Iwase ◽  
...  
Keyword(s):  
Older Adults ◽  
Health Literacy ◽  
Cognitive Function ◽  
Cognitive Decline ◽  
Depression Scale ◽  
Community Dwelling ◽  
Subjective Cognitive Decline ◽  
Healthy Community ◽  
Community Dwelling Older Adults ◽  
The Relationship

Few studies have examined the effects of health literacy on people at risk of developing dementia; its effects on the pathogenesis of subjective cognitive decline (SCD) are particularly unclear. This study aimed to clarify the relationship between health literacy and SCD in a population of healthy community-dwelling older adults. SCD status was assessed using the Cognitive Function domain of the Kihon Checklist (KCL-CF). Health literacy, in turn, was evaluated using the Communicative and Critical Health Literacy (CCHL) scale. Global cognitive function and depressive symptoms were evaluated using the Mini-Mental State Examination (MMSE) and a five-item version of the Geriatric Depression Scale (GDS-5), respectively. Participants who were suspected of having SCD were significantly older than their non-SCD peers, and scored significantly worse on the CCHL, MMSE, and GDS-5. In addition, SCD status was found to be associated with CCHL and GDS-5 scores, as well as age, according to a logistic regression analysis. These findings suggest that low health literacy is linked to SCD morbidity in healthy community-dwelling older adults and should prove useful in the planning of dementia prevention and intervention programs for this population.

P2-591: TAU TANGLE DENSITY MODIFIES THE RELATIONSHIP BETWEEN HOSPITALIZATION AND COGNITIVE DECLINE IN COMMUNITY-DWELLING OLDER ADULTS

2006 ◽  
Vol 14 (7S_Part_17) ◽  
pp. P964-P964
Author(s):  
Bryan D. James ◽  
Robert S. Wilson ◽  
Patricia A. Boyle ◽  
Raj C. Shah ◽  
Melissa Lamar ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Community Dwelling ◽  
Community Dwelling Older Adults ◽  
The Relationship
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