CONTRIBUTION TO THE PROBLEM OF THE REGENERATION OF NERVE FIBRES IN THE CENTRAL NERVOUS SYSTEM AFTER OPERATIVE DAMAGE IN THE EARLY POSTNATAL PERIOD

1965 ◽  
Vol 60 (2) ◽  
pp. 165-180 ◽  
Author(s):  
S. Reiniš
1970 ◽  
Vol 52 (3) ◽  
pp. 583-592
Author(s):  
K. J. FRIEDMAN ◽  
A. D. CARLSON

1. The nature of insect curarization has been investigated in the cockroach, P. americana. Mechanical studies of leg contraction revealed that dTC, whether injected into the abdomen, injected into a leg or applied to the metathoracic ganglion, produces failure of contraction. 2. The contraction failure caused by injecting dTC into a leg or by applying dTC to the metathoracic ganglion could be reversed by washing the drug out of the affected area. 3. The central nervous system does not appear to be essential for curare-induced contraction failure. The contraction of metathoracic legs deprived of their metathoracic ganglion is abolished in the presence of curare. 4. Since curare produces contraction failure when applied to the metathorax and when injected into a leg, the site of curare action must be present in both these locations. The motor nerve fibres are present in both these locations and it is proposed that contraction failure is due to the action of curare on these fibres.


1948 ◽  
Vol s3-89 (5) ◽  
pp. 89-102
Author(s):  
A. BRODAL ◽  
R. G. HARRISON

Baker's (1946) acid haematein and pyridine-extraction control tests, claimed to be specific for phospholipines (Baker, 1947), have been applied to various parts of the central nervous system of rats and man. The sudan black method for the detection of lipoids and the nile blue method for the staining of acidic lipoids have also been used. The findings are in agreement with older statements in the literature that myelin contains a considerable amount of phospholipines. It was impossible to determine whether galactolipines or neutral lipoids are also present. In the acid haematein-stained sections finer fibres were seen than when other stains for myelin sheaths are employed. Fibres with a diameter of 0.5 µ or even somewhat less were stained in various parts of the central nervous system of rats. It is regarded as probable from these findings that fibres down to 0.5 µ or even smaller possess a lipoid investment. These observations lend support to the now commonly accepted view that the distinction between myelinated and so-called unmyelinated fibres is arbitrary. Some observations are made, however, which indicate that the presence of truly unmyelinated fibres cannot be excluded.


Author(s):  
J. S. Alexandrowicz

In the dorsal wall of the abdomen in the Paguridae muscle receptor organs have been found similar to those in the Macrura. In each of the first to fifth abdominal segments there are two receptor units on each side. A receptor unit consists of a long thread-like muscle, and a nerve cell connected with this muscle and sending its axon towards the central nervous system. The muscles of each pair run close together in the layer of the dorsal (extensor) muscles, but are independent from the latter following a more or less different course.The nerve cells in each pair of muscle receptor organs are of two types. One of them has several very long distal processes expanding over one of the muscles. The other cell has one stout distal process giving off numerous but very short branches forming with their subdivisions a dense tuft of fibres terminating in the second muscle. The axons of the cells associate with one of the branches of motor nerves supplying the dorsal muscles and pass along these branches into the main nerve trunks of the respective segments.Each receptor organ is supplied by several nerve fibres coming from the central nervous system.


1941 ◽  
Vol 18 (1) ◽  
pp. 50-54 ◽  
Author(s):  
W. HOLMES ◽  
R. J. PUMPHREY ◽  
J. Z. YOUNG

1. The structure of the myelinated fibres of prawns is described, and the homologies of the nucleated sheath which lies between the axon and the fatty layer discussed. 2. The relative thickness of the myelin sheath increases with decrease in total diameter of the fibre along a curve similar in shape to that found in vertebrates and earthworms. 3. Nodes of Ranvier are found in the sheaths of most fibres of a diameter greater than about 13µ 4. The nodes are similar to those in vertebrate nerves in that the myelin sheath is interrupted at the node. 5. The conduction velocity of fibres in the central nervous system of axon diameter 26µ and total diameter 35µ is between 18 and 23 m. per sec., a rate faster than is found in the "unmyelinated" fibres of similar size in other crustacea.


1958 ◽  
Vol s3-99 (46) ◽  
pp. 243-261
Author(s):  
QUENTIN BONE

A detailed description of the system of peripheral nerve-cells upon the gut and diverticulum of amphioxus (Branchiostoma) is given; it is shown experimentally by means of degeneration experiments that these cells are connected with the central nervous system by their own axons, which run in the dorsal-root nerves. The form and connexion of the cells are described, special attention is paid to the problems of the multinucleate cells in the plexus, and to the occurrence of possible asynaptic connexion between neighbouring nerve-cells. No sheath-cells have been observed upon the peripheral nerve-fibres, either within the atrial plexus or upon the dorsal-root nerve bundles; earlier misinterpretations of the nuclei of the cells of the epineurium around the dorsal nerve bundles are discussed. The origin of the atrial system in ontogeny is discussed; it is suggested that it arises in an analogous manner to the enteric plexuses of vertebrates, by outgrowth from the central nervous system. The part that this system of nerve-cells plays in the life of the animal is not known. Finally, the relation of this system of cells to that found upon the guts of other groups of animals is discussed, and it is concluded that the system is not homologous with the enteric systems of nerve-cells in the vertebrates.


In a previous paper in these ‘Proceeding’ (E. C. Hoff, 1932), a report was given of investigation concerning the boutons terminaux which constitute the terminals of nerve fibres around dendrites and perikarya in the central nervous system. It was shown that 24 to 48 hours after selection of the afferent roots of the spinal cord of the cat, the boutons undergo degenerative swelling and granulation. This degenerative process reaches a climax in 3 days and ends in the complete destruction of the terminals after 4 to 6 days.* In the present studies, the normal synapses of the monkey have been investigated; further, the phenomenon of degeneration of boutons following section of nerve fibres has been applied as a method for determining the endings of the pyramidal tracts in the cat and the monkey.


1900 ◽  
Vol 39 (3) ◽  
pp. 685-702 ◽  
Author(s):  
Robert Kennedy

From the point of view of its function, a nerve fibre is a conductor of nervous impulses, and as such is the path of communication between two structures, the one situated in the central nervous system, and the other in the periphery. In the mixed nerve, such as the sciatic, the nerve fibres are distinguished as afferent or as efferent, according as they conduct impulses originating at the periphery, and received by a cell in the central nervous system, or vice versâ. It has long since been shown that nerve fibres are capable of conducting impulses in either direction, but normally, from their anatomical connections, the individual nerve fibres are conductors for impulses only in the one or in the other direction. This is proved by the Wallerian method of investigation, as on severance of the posterior spinal root distal to the ganglion only certain fibres degenerate and the conductivity of the nerve only for afferent impulses is lost, while the severance of the anterior root is followed by the degeneration of the remainder with loss of functions depending on efferent impulses.


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