BACKGROUND: The pandemic caused by SARS-Corona Virus-2 (COVID-19) is far from over. There has been
ongoing new infections across the globe. The clinical course of the disease is varied among different individuals. The
prediction of severity and mortality is very difcult but quite essential for timely escalation of the treatment. This is a comparative study of
clinical, biochemical parameters among the survivors and non survivors of COVID-19 infection. METHODOLOGY: This is a retrospective
study conducted in a tertiary care hospital in South India. This study was an audit of 39 survivors and 39 non survivors of COVID-19 infection.
These patients were matched with age and gender. The clinical prole, Biochemical parameters and the clinical course among the two groups
were compared and analyzed. RESULTS: 39 survivors and 39 non survivors were included in the study. The two groups were age and gender
matched. The symptoms were fever, cough, breathlessness, fatigue, myalgia, body ache, diarrhea. Breathlessness was more common among
patients who did not survive. Pneumonia severity index was class 1 and class 2 among patients who survived. PSI was class 4 and class 5 among
the patients who did not survive. This difference was statistically signicant. It was seen that there were signicant number of comorbidities and
inammatory markers like CRP, D DIMER, LDH, S. Ferritin seen among non survivors compared to the survivors. The study CONCLUSION:
shows that presence of comorbidities has an adverse impact on the outcome of the patients with COVID-19 infection. The elevated inammatory
markers like CRP, D Dimer and LDH predicted poor outcome. Pneumonia severity index was a useful marker to predict the outcome among
patients of COVID.
