scholarly journals Laparoscopic Resection of Schwannoma of the Ascending Colon

2015 ◽  
Vol 9 (1) ◽  
pp. 15-19 ◽  
Author(s):  
Yoshihiko Tashiro ◽  
Fumio Matsumoto ◽  
Keiko Iwama ◽  
Ai Shimazu ◽  
Sei Matsumori ◽  
...  
Keyword(s):  
Submucosal Tumor ◽  
Smooth Muscle Actin ◽  
Immunohistochemical Analysis ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Ki 67 ◽  
D2 Lymph Node Dissection ◽  
Benign Schwannoma ◽  
S 100 ◽  
Laparoscopic Right Hemicolectomy

Schwannomas of the colon are rare and difficult to diagnose preoperatively. We report a case of schwannoma of the ascending colon that was resected laparoscopically. A 64-year-old woman was referred to our hospital by her local clinic for further evaluation and management of a submucosal tumor of the ascending colon. A definitive preoperative diagnosis could not be reached despite examinations. Gastrointestinal stromal tumor, leiomyoma and lymphoma were the differential diagnoses. We performed a laparoscopic right hemicolectomy with D2 lymph node dissection. Histological findings with hematoxylin-eosin staining revealed spindle-like tumor cells, and immunohistochemical analysis showed that the tumor was positive for S-100 but negative for c-kit, CD34, smooth muscle actin and desmin, with a Ki-67 index of <5%. Thus, the diagnosis in this case was benign schwannoma of the ascending colon.

scholarly journals A Case of Benign Schwannoma of the Ascending Colon Treated With Laparoscopic-Assisted Wedge Resection

2013 ◽  
Vol 98 (4) ◽  
pp. 315-318 ◽  
Author(s):  
Se-Jin Baek ◽  
Won Hwangbo ◽  
Jin Kim ◽  
In-Sun Kim
Keyword(s):  
Submucosal Tumor ◽  
Wedge Resection ◽  
Ascending Colon ◽  
Mesenchymal Tumors ◽  
Benign Schwannoma ◽  
S 100 ◽  
Colon And Rectum ◽  
Laparoscopic Assisted ◽  
Specific Symptoms ◽  
Diffuse Positivity

Abstract Isolated colonic schwannomas are rare gastrointestinal mesenchymal tumors. Only a small number of cases have been reported. Occurrence of these tumors is more common in the stomach than in the large intestine. These spindle cell lesions are distinct from leiomyoma, leiomyosarcoma, and gastrointestinal stromal tumors because the tumor cells have a distinct immunophenotype, with strong diffuse positivity for S-100 and vimentin, as well as corroborative negative staining of CD117 and smooth muscle markers. We present a case of colonic schwannoma in a 70-year-old woman who had no specific symptoms. The patient was diagnosed with a submucosal tumor in the ascending colon on colonoscopy and abdominal computed tomography. Laparoscopic-assisted wedge resection of colon was performed. The very rare pathologic diagnosis of ascending schwannoma was made postoperatively. This case is interesting because schwannomas of the colon and rectum are extremely rare and are treated by laparoscopic-assisted wedge resection.

scholarly journals Preoperatively diagnosed gastric collision tumor with mixed adenocarcinoma and gastrointestinal stromal tumor: a case report and literature review

2021 ◽  
Author(s):  
Kunihiko Matsuno ◽  
Yoshikazu Kanazawa ◽  
Daisuke Kakinuma ◽  
Nobutoshi Hagiwara ◽  
Fumihiko Ando ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Distal Gastrectomy ◽  
Submucosal Tumor ◽  
Smooth Muscle Actin ◽  
Collision Tumor ◽  
Stromal Tumor ◽  
Lower Body ◽  
Muscle Actin ◽  
First Case ◽  
S 100

AbstractReports of gastric collision tumors, comprising adenocarcinoma and gastrointestinal stromal tumor, are extremely rare. Here, we report the case of a 68-year-old male who was diagnosed with a lower-body, moderately differentiated, tubular-type adenocarcinoma and submucosal tumor and underwent an elective D2 distal gastrectomy. The tumor cells of the gastrointestinal stromal tumor were positive for H-caldesmon and CD117, weakly positive for smooth muscle actin and DOG-1, and negative for desmin, S-100 protein, CD31, and AE1/AE3. The tumor had grown into a mixed form of adenocarcinoma and gastrointestinal stromal tumor. Thus, we report the first case of a preoperatively diagnosed collision tumor in the stomach consisting of adenocarcinoma and gastrointestinal stromal tumor.

scholarly journals A Rare Primary Tumor of the Thyroid Gland: A New Case of Leiomyoma and Literature Review

2018 ◽  
Vol 12 ◽  
pp. 117955491881353
Author(s):  
Yanling Zhang ◽  
Heng Tang ◽  
Huaiyuan Hu ◽  
Xiang Yong
Keyword(s):  
Thyroid Gland ◽  
Tumor Cells ◽  
Immunohistochemical Staining ◽  
Smooth Muscle Actin ◽  
Frozen Sections ◽  
Ki 67 ◽  
Eosinophilic Cytoplasm ◽  
S 100 ◽  
Painless Mass ◽  
The Right

Primary leiomyomas of the thyroid are very rare. We here report a case of a 53-year-old woman with a painless mass at the right thyroid, revealed by physical examination. The patient underwent a lobectomy. Frozen sections showed a spindle cell tumor of the thyroid gland. The nuclei of some of the tumor cells were obviously enlarged and deeply stained. Pseudocapsule invasion was observed in small foci. Samples showed neither mitosis nor necrosis and the nature of the tumor was difficult to determine. Paraffin sections showed a well-circumscribed nodular composed of intersecting fascicles of spindled to slightly epithelioid cells with eosinophilic cytoplasm and blunt-ended, cigar-shaped nuclei. We observed no significant nuclear atypia, mitotsis, or necrosis. Immunohistochemical staining showed the tumor cells to be positive for α-smooth muscle actin and h-caldesmon but negative for TG, TTF1, PAX8, S-100, CT, CK, and CD34. The ki-67 index was very low (<1%). Primary thyroid leiomyoma is rare and difficult to diagnose using frozen sections. Diagnosis requires immunohistochemical staining. Leiomyoma may be mistaken for other thyroid tumors also characterized by spindle cells.

scholarly journals Intraosseous Schwannoma of the Proximal Humarus With Pathologic Fracture

2021 ◽  
Author(s):  
huajun jiang ◽  
Wei Qu ◽  
Yuxuan Wu ◽  
Jingjing Yang
Keyword(s):  
Proximal Humerus ◽  
Pathologic Fracture ◽  
Bone Allograft ◽  
Excisional Biopsy ◽  
Pathological Examination ◽  
Ki 67 ◽  
Benign Schwannoma ◽  
S 100 ◽  
Magnetic Resonance Imaging Mri ◽  
The Right

Abstract Purpose Intraosseous schwannomas are extremely rare in the humerus, and less than 5 cases have been reported previously in the literature. This is the first report of its origin in the proximal humerus with pathologic fracture. we herein present this case for discussing the reason for its rarity and sharing our experience of management.Case presentation A 55-year-old female patient who presented with pain in the right shoulder, which caused by tripping and falling over a board. Radiographs, computed tomography (CT) and magnetic resonance imaging (MRI) showed considerable tumor in proximal humerus, which connected with a fracture. For this suspected tumor, we performed two operations. Pathological examination demonstrated typical picture of a schwannoma, showing whorls and interlacing fascicles of schwannoma spindle cells. Immunohistochemistry, The tumor cells were diffusely positive for S-100 protein, SOX-10 and CD68, while they were completely negative for desmin, DOG-1, AE1/AE3 and P63. The ki-67 index was about 10%. No mitoses or features of malignancy were identified. Finally, a diagnosis of benign schwannoma with focal of actively proliferated cells was made.Methods The treatment for intraosseous neurilemmomais with pathologic fracture include excisional biopsy, curettage, bone allograft, and fracture fixation. Results The patient recovered well. After the surgery, the patient gradually regained mobility and pain subsided. There was no recurrence after 6 months follow-up by X-ray.Conclusion In our case, the tumor with higher CD68 staining were likely to demonstrate that the tumor volume increase is not only based on cell proliferation, but also intratumoral hemorrhage, vascularization, and inflammation, which may be produce rarefaction of the bone and lead to bone fracture after a trivial trauma.

scholarly journals Intraosseous schwannoma of the proximal humarus with pathologic fracture

2021 ◽  
Author(s):  
Huajun Jiang ◽  
Wei Qu ◽  
Yuxuan Wu ◽  
Jingjing Yang
Keyword(s):  
Proximal Humerus ◽  
Pathologic Fracture ◽  
Bone Allograft ◽  
Excisional Biopsy ◽  
Pathological Examination ◽  
Ki 67 ◽  
Benign Schwannoma ◽  
S 100 ◽  
Magnetic Resonance Imaging Mri ◽  
The Right

Abstract Purpose: Intraosseous schwannomas are extremely rare in the humerus, and less than 5 cases have been reported previously in the literature. This is the first report of its origin in the proximal humerus with pathologic fracture. we herein present this case for discussing the reason for its rarity and sharing our experience of management.Case presentation: A 55-year-old female patient who presented with pain in the right shoulder, which caused by tripping and falling over a board. Radiographs, computed tomography (CT) and magnetic resonance imaging (MRI) showed considerable tumor in proximal humerus, which connected with a fracture. For this suspected tumor, we performed two operations. Pathological examination demonstrated typical picture of a schwannoma, showing whorls and interlacing fascicles of schwannoma spindle cells. Immunohistochemistry, The tumor cells were diffusely positive for S-100 protein, SOX-10 and CD68, while they were completely negative for desmin, DOG-1, AE1/AE3 and P63. The ki-67 index was about 10%. No mitoses or features of malignancy were identified. Finally, a diagnosis of benign schwannoma with focal of actively proliferated cells was made.Methods: The treatment for intraosseous neurilemmomais with pathologic fracture include excisional biopsy, curettage, bone allograft, and fracture fixation.Results: The patient recovered well. After the surgery, the patient gradually regained mobility and pain subsided. There was no recurrence after 6 months follow-up by X-ray.Conclusion: In our case, the tumor with higher CD68 staining were likely to demonstrate that the tumor volume increase is not only based on cell proliferation, but also intratumoral hemorrhage, vascularization, and inflammation, which may be produce rarefaction of the bone and lead to bone fracture after a trivial trauma.

scholarly journals Current Recommendations on Diagnosis and Management of Right-Sided Diverticulitis

2009 ◽  
Vol 2009 ◽  
pp. 1-4 ◽  
Author(s):  
Dana A. Telem ◽  
Kerri E. Buch ◽  
Scott Q. Nguyen ◽  
Edward H. Chin ◽  
Kaare J. Weber ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Diverticular Disease ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Diagnosis And Management ◽  
Colon Diverticulitis ◽  
Laparoscopic Right Hemicolectomy ◽  
Colonic Diverticular Disease

We present the case of a 52-year-old female with recurrent symptomatic ascending colon diverticulitis who ultimately underwent elective laparoscopic right hemicolectomy. The following is a case report and literature review pertaining to right colonic diverticular disease.

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