scholarly journals A Case of Benign Schwannoma of the Ascending Colon Treated With Laparoscopic-Assisted Wedge Resection

2013 ◽  
Vol 98 (4) ◽  
pp. 315-318 ◽  
Author(s):  
Se-Jin Baek ◽  
Won Hwangbo ◽  
Jin Kim ◽  
In-Sun Kim
Keyword(s):  
Submucosal Tumor ◽  
Wedge Resection ◽  
Ascending Colon ◽  
Mesenchymal Tumors ◽  
Benign Schwannoma ◽  
S 100 ◽  
Colon And Rectum ◽  
Laparoscopic Assisted ◽  
Specific Symptoms ◽  
Diffuse Positivity

Abstract Isolated colonic schwannomas are rare gastrointestinal mesenchymal tumors. Only a small number of cases have been reported. Occurrence of these tumors is more common in the stomach than in the large intestine. These spindle cell lesions are distinct from leiomyoma, leiomyosarcoma, and gastrointestinal stromal tumors because the tumor cells have a distinct immunophenotype, with strong diffuse positivity for S-100 and vimentin, as well as corroborative negative staining of CD117 and smooth muscle markers. We present a case of colonic schwannoma in a 70-year-old woman who had no specific symptoms. The patient was diagnosed with a submucosal tumor in the ascending colon on colonoscopy and abdominal computed tomography. Laparoscopic-assisted wedge resection of colon was performed. The very rare pathologic diagnosis of ascending schwannoma was made postoperatively. This case is interesting because schwannomas of the colon and rectum are extremely rare and are treated by laparoscopic-assisted wedge resection.

scholarly journals Laparoscopic Resection of Schwannoma of the Ascending Colon

2015 ◽  
Vol 9 (1) ◽  
pp. 15-19 ◽  
Author(s):  
Yoshihiko Tashiro ◽  
Fumio Matsumoto ◽  
Keiko Iwama ◽  
Ai Shimazu ◽  
Sei Matsumori ◽  
...  
Keyword(s):  
Submucosal Tumor ◽  
Smooth Muscle Actin ◽  
Immunohistochemical Analysis ◽  
Right Hemicolectomy ◽  
Ascending Colon ◽  
Ki 67 ◽  
D2 Lymph Node Dissection ◽  
Benign Schwannoma ◽  
S 100 ◽  
Laparoscopic Right Hemicolectomy

Schwannomas of the colon are rare and difficult to diagnose preoperatively. We report a case of schwannoma of the ascending colon that was resected laparoscopically. A 64-year-old woman was referred to our hospital by her local clinic for further evaluation and management of a submucosal tumor of the ascending colon. A definitive preoperative diagnosis could not be reached despite examinations. Gastrointestinal stromal tumor, leiomyoma and lymphoma were the differential diagnoses. We performed a laparoscopic right hemicolectomy with D2 lymph node dissection. Histological findings with hematoxylin-eosin staining revealed spindle-like tumor cells, and immunohistochemical analysis showed that the tumor was positive for S-100 but negative for c-kit, CD34, smooth muscle actin and desmin, with a Ki-67 index of <5%. Thus, the diagnosis in this case was benign schwannoma of the ascending colon.

scholarly journals Ascending Colon Schwannoma Surgically Treated after Accurate Preoperative Diagnosis

2020 ◽  
Vol 14 (3) ◽  
pp. 483-490
Author(s):  
Yohei Kojima ◽  
Takashi Yamaguchi ◽  
Satoshi Taguchi ◽  
Eri Kondo ◽  
Masaaki Yokoyama ◽  
...  
Keyword(s):  
Preoperative Diagnosis ◽  
Submucosal Tumor ◽  
Wedge Resection ◽  
S100 Protein ◽  
Endoscopic Biopsy ◽  
Bloody Stool ◽  
Ascending Colon ◽  
Mesenchymal Tumors ◽  
Colon Wall ◽  
Accurate Preoperative Diagnosis

Colorectal schwannomas are rare and usually benign gastrointestinal mesenchymal tumors. However, these tumors are often overtreated, possibly owing to misleading malignant potential. To our knowledge, there have been no previous reports of ascending colon schwannoma preoperatively diagnosed as benign schwannoma. Herein, we report a case of ascending colon schwannoma accurately diagnosed by endoscopic biopsy and successfully treated by wedge resection. The patient was a 76-year-old woman with complaints of bloody stool. She had no relevant past medical history. Radiological findings revealed a protruded mass in the ascending colon, and colonoscopy revealed a submucosal tumor measuring approximately 3 cm in diameter with a reddish and uneven surface. Histological and immunohistochemical analysis for vimentin and S100 protein of the specimen obtained by endoscopic biopsy confirmed the diagnosis of schwannoma. Thus, we performed laparoscopy-assisted endoscopic full-thickness resection of the ascending colon wall, as appropriate for a benign soft tissue tumor. The postoperative course has been uneventful for 2 years. This case demonstrates that colonic schwannoma can be successfully treated with adequate resection if an accurate preoperative diagnosis is made, thereby avoiding overtreatment, such as surgery for colorectal tumor including lymph node dissection. Preoperatively diagnosed schwannomas should be treated by wedge resection, with postoperative pathological findings confirming the presence or absence of malignancy. Additional resection should be considered for very rare cases of coexisting malignant tissue.

scholarly journals A Rare Case of Gastric Schwannoma: A Case Report and Literature Review

2020 ◽  
Vol 13 (1) ◽  
pp. 330-335 ◽  
Author(s):  
Senichiro Yanagawa ◽  
Kenichi Kagemoto ◽  
Hidehiro Tanji ◽  
Shinya Kodama ◽  
Yukio Takeshima ◽  
...  
Keyword(s):  
Submucosal Tumor ◽  
Imaging Techniques ◽  
Treatment Options ◽  
Surgical Margin ◽  
Pathological Examination ◽  
Positive Staining ◽  
Gastric Schwannoma ◽  
Precise Diagnosis ◽  
S 100 ◽  
Laparoscopic Assisted

In general, schwannoma is a benign and slow-glowing neoplasm that rarely occurs in the gastrointestinal tract as a submucosal tumor (SMT), with the most common site being the stomach. As gastric schwannoma (GS) is a rare tumor, there is limited data in the literature about its clinical features. The diagnosis of schwannoma can only be made by pathological examination with positive staining for S-100 protein. It is necessary to obtain an accurate diagnosis to introduce optimal treatment options preoperatively. However, a precise diagnosis of GS is difficult, even with modern imaging techniques. On the other hand, a complete resection with a negative surgical margin (R0) of GS is considered the best treatment, with an excellent prognosis. We present a case of a 66-year-old female patient who underwent laparoscopic-assisted wedge gastrectomy for gastric SMT, pathologically diagnosed as GS, with positive staining for S-100 protein and negative for c-kit and CD34. At 12-month follow-up after surgery, there was no recurrence or metastasis of GS. Our treatment is appropriate and effective in case of GS exceeding 50 mm.

scholarly journals Synchronous Gastric Gastrointestinal Stromal Tumor and Colon Adenocarcinoma: A Case Report

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Thivi Vasilakaki ◽  
Kalliroi Koulia ◽  
Aikaterini Tsavari ◽  
Elissavet Arkoumani ◽  
Efstratios Kouroumpas ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Regional Lymph Node ◽  
Wedge Resection ◽  
Rare Event ◽  
Colon Adenocarcinoma ◽  
Additional Treatment ◽  
Stromal Tumor ◽  
Gastric Body ◽  
Ascending Colon ◽  
Mesenchymal Tumors

Gastrointestinal stromal tumors (GISTs) represent the majority of primary mesenchymal tumors of the gastrointestinal tract. They are generally considered to be solitary tumors and therefore the synchronous occurrence with other primary malignancies of gastrointestinal track is considered a rare event. Here we present the case of a 75-year-old man admitted to our hospital with a 10-day history of gastrointestinal bleeding. Colonoscopy revealed an ulcerative mass of 4 cm in diameter in the ascending colon. Gastroscopy revealed a bulge in the gastric body measuring 1 cm in diameter with normal overlying mucosa. Surgical intervention was suggested and ileohemicolectomy with regional lymph node resection along with gastric wedge resection was performed. Pathologic examination of the ascending colon mass showed an invasive moderately differentiated adenocarcinoma stage III B (T3N1M0). Grossly resected wedge of stomach showed a well circumscribed intramural tumor which microscopically was consistent with essentially benign gastrointestinal stromal tumor (according to Miettinen criteria). The patient did not receive additional treatment. Two years later the patient showed no evidence of recurrence or metastasis.

scholarly journals A unique method for management of benign colonic masses: case report

2021 ◽  
Vol 9 (1) ◽  
pp. 217
Author(s):  
Anushtup De ◽  
Bhaskar Nandi ◽  
Jaspreet Singh Bajwa ◽  
Rajesh K. Singh ◽  
Deepika Parwan ◽  
...  
Keyword(s):  
Intestinal Obstruction ◽  
Young Female ◽  
Ascending Colon ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct ◽  
Unique Method ◽  
Subacute Intestinal Obstruction ◽  
Laparoscopic Assisted ◽  
Specific Symptoms

Even though lipomas are most common non-epithelial tumors of the large intestine, they mostly present with non-specific symptoms. Intussusception is the most common morbidity related to such lesions and may present as intestinal obstruction. We present here a case of a young female who presented to gastroenterology department as a case of pain abdomen and nausea and a provisional diagnosis of subacute intestinal obstruction was kept. Contrast enhanced CT confirmed a diagnosis of intussusception due to an ascending colon mass? likely lipoma. The colonoscopy was done and biopsy was taken which was non-specific for malignancy. Patient, after taking due consent, was taken for surgery and laparoscopic assisted submucosal excision of lipoma was done and we will discuss the same. Endoscopic excision of lipomas has been reported but when failed, mostly segmental resection of the colon has been reported. To the best of our knowledge, this is the second reported case of laparoscopic assisted colotomy with submucosal excision of an intussuscepting colonic lipoma and first one in ascending colon.

scholarly journals Preoperatively diagnosed gastric collision tumor with mixed adenocarcinoma and gastrointestinal stromal tumor: a case report and literature review

2021 ◽  
Author(s):  
Kunihiko Matsuno ◽  
Yoshikazu Kanazawa ◽  
Daisuke Kakinuma ◽  
Nobutoshi Hagiwara ◽  
Fumihiko Ando ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Distal Gastrectomy ◽  
Submucosal Tumor ◽  
Smooth Muscle Actin ◽  
Collision Tumor ◽  
Stromal Tumor ◽  
Lower Body ◽  
Muscle Actin ◽  
First Case ◽  
S 100

AbstractReports of gastric collision tumors, comprising adenocarcinoma and gastrointestinal stromal tumor, are extremely rare. Here, we report the case of a 68-year-old male who was diagnosed with a lower-body, moderately differentiated, tubular-type adenocarcinoma and submucosal tumor and underwent an elective D2 distal gastrectomy. The tumor cells of the gastrointestinal stromal tumor were positive for H-caldesmon and CD117, weakly positive for smooth muscle actin and DOG-1, and negative for desmin, S-100 protein, CD31, and AE1/AE3. The tumor had grown into a mixed form of adenocarcinoma and gastrointestinal stromal tumor. Thus, we report the first case of a preoperatively diagnosed collision tumor in the stomach consisting of adenocarcinoma and gastrointestinal stromal tumor.

scholarly journals Abdominal Tuberculosis

2017 ◽  
Vol 28 (1) ◽  
pp. 39-45
Author(s):  
Md Ismail ◽  
Golam Azam
Keyword(s):  
Clinical Presentation ◽  
Imaging Study ◽  
Abdominal Tuberculosis ◽  
Clinical Feature ◽  
Ascending Colon ◽  
Diagnostic Dilemma ◽  
Mdr Tb ◽  
Colon And Rectum ◽  
Frequent Site ◽  
High Index Of Suspicion

Abdominal tuberculosis constitute up to 12% of extrapulmonary TB and is sixth frequent site of extrapulmonary involvement. The most common sites of involvement is the ileocaecalregion. Other site of involvement in descending order are ascending colon jejunum, appendix, duodenum, stomach, esophagus, sigmoid colon and rectum. Abdominal TB has diagnostic dilemma due to its diverse and non-specific clinical presentation and has no single most specific, sensitive diagnostic test. A high index of suspicion, common and rare clinical feature, adequate imaging study, endoscopy, enteroscopy, laparoscopy, laparotomy, biopsy with histopathology, Mycobacterial isolation, Quantiferon-TB Gold, GeneXpert Assay, MULTIPLEX PCR and clinical response to anti TB therapy are considered for early diagnosis to reduce morbidity and mortality. Six month antiTB regime is effective as nine or 12month therapy. MDR TB and frequent interruption of therapy should considered in nonresponder to standard therapy. Surgery is required for minority cases that developed complications not responding to medical therpy.Medicine Today 2016 Vol.28(1): 39-45

scholarly journals A case of advanced mucinous ascending colon cancer resembling a submucosal tumor

2012 ◽  
Vol 73 (10) ◽  
pp. 2606-2609
Author(s):  
Takanobu YAMADA ◽  
Insop HAN ◽  
Yasuyuki JIN ◽  
Kimiatsu HASUO ◽  
Yasushi RINO ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Submucosal Tumor ◽  
Ascending Colon ◽  
Ascending Colon Cancer

scholarly journals Botryoid-type Embryonal Rhabdomyosarcoma of Liver in a Young Cat

1997 ◽  
Vol 34 (6) ◽  
pp. 618-621 ◽  
Author(s):  
G. Minkus ◽  
M. Hillemanns
Keyword(s):  
Tumor Heterogeneity ◽  
Neuron Specific Enolase ◽  
Cell Types ◽  
Embryonal Rhabdomyosarcoma ◽  
Age Group ◽  
Pediatric Age ◽  
Mesenchymal Tumors ◽  
Pediatric Age Group ◽  
S 100 ◽  
Malignant Mesenchymal Tumor

An unusual malignant mesenchymal tumor arising in the liver of a 2-year-old cat is described. Histologically, the tumor showed considerable variation in growth pattern, cellularity, and cell types. Phenotypical diversity was confirmed by immunohistochemistry, showing expression of desmin, vimentin, S-100, and neuron-specific enolase in various areas of the tumor. On the basis of histopathology, immunohistochemistry, electron microscopy, and gross morphology, the tumor was classified as botryoid-type embryonal rhabdomyosarcoma. Differential diagnosis included so-called undifferentiated (embryonal) sarcoma of the liver, a rare tumor of the pediatric age group in humans. Problems of tumor heterogeneity and differentiation in mesenchymal tumors are discussed.

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