HIV Replication in the Central Nervous System of AIDS Patients

2015 ◽  
pp. 69-81
Author(s):  
R. Vazeux ◽  
M. C. Cumont ◽  
L. Montagnier
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hiv Replication ◽  
Aids Patients ◽  
The Central Nervous System

Anomalies in Nef expression within the central nervous system of HIV-1 positive individuals/AIDS patients with or without AIDS dementia complex

1998 ◽  
Vol 4 (3) ◽  
pp. 291-300 ◽  
Author(s):  
Dale A Mcphee ◽  
Alison L Greenway ◽  
Gavan Holloway ◽  
Karen Smith ◽  
Nick Deacon ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Aids Dementia Complex ◽  
Aids Patients ◽  
Aids Dementia ◽  
The Central Nervous System ◽  
Hiv 1

scholarly journals Human Immunodeficiency Virus Type-1 (HIV-1) Transcriptional Regulation, Latency and Therapy in the Central Nervous System

Vaccines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1272
Author(s):  
Joseph Hokello ◽  
Adhikarimayum Lakhikumar Sharma ◽  
Priya Tyagi ◽  
Alok Bhushan ◽  
Mudit Tyagi
Keyword(s):  
Central Nervous System ◽  
Human Immunodeficiency Virus ◽  
Nervous System ◽  
Transcriptional Regulation ◽  
Antiretroviral Therapy ◽  
Hiv Infection ◽  
Combination Antiretroviral Therapy ◽  
Hiv Replication ◽  
Immunodeficiency Virus ◽  
The Central Nervous System

The central nervous system (CNS) is highly compartmentalized and serves as a specific site of human immunodeficiency virus (HIV) infection. Therefore, an understanding of the cellular populations that are infected by HIV or that harbor latent HIV proviruses is imperative in the attempts to address cure strategies, taking into account that HIV infection and latency in the CNS may differ considerably from those in the periphery. HIV replication in the CNS is reported to persist despite prolonged combination antiretroviral therapy due to the inability of the current antiretroviral drugs to penetrate and cross the blood–brain barrier. Consequently, as a result of sustained HIV replication in the CNS even in the face of combination antiretroviral therapy, there is a high incidence of HIV-associated neurocognitive disorders (HAND). This article, therefore, provides a comprehensive review of HIV transcriptional regulation, latency, and therapy in the CNS.

Pathological findings in the central nervous system of AIDS patients on assumed antiretroviral therapeutic regimens

AIDS ◽  
2002 ◽  
Vol 16 (14) ◽  
pp. 1925-1928 ◽  
Author(s):  
Luca Vago ◽  
Sara Bonetto ◽  
Manuela Nebuloni ◽  
Piergiorgio Duca ◽  
Luca Carsana ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pathological Findings ◽  
Aids Patients ◽  
The Central Nervous System

Aspergillus sydowii. [Descriptions of Fungi and Bacteria].

2000 ◽  
Author(s):  
Z. Kozakiewicz
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Geographical Distribution ◽  
World Wide ◽  
Cotton Yarn ◽  
Aspergillus Sydowii ◽  
Aids Patients ◽  
The Central Nervous System

Abstract A description is provided for Aspergillus sydowii. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Primarily a soil species (DOMSCH et al., 1980), but also isolated from other substrata, including wallpaper, talc, paint and cotton yarn (CABI BIOSCIENCE, 1999). DISEASE: On man isolated from keratomycosis (mycoses), bones, joints, lungs and the central nervous system (SMITH, 1989). In addition it has been isolated from onychomycosis (SUMMERBELL et al., 1989), from AIDS patients (NEVES et al., 1998) and as component of hospital air mycoflora (GOODLEY et al., 1994). GEOGRAPHICAL DISTRIBUTION: World-wide.

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