Anomalies in Nef expression within the central nervous system of HIV-1 positive individuals/AIDS patients with or without AIDS dementia complex

1998 ◽  
Vol 4 (3) ◽  
pp. 291-300 ◽  
Author(s):  
Dale A Mcphee ◽  
Alison L Greenway ◽  
Gavan Holloway ◽  
Karen Smith ◽  
Nick Deacon ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Aids Dementia Complex ◽  
Aids Patients ◽  
Aids Dementia ◽  
The Central Nervous System ◽  
Hiv 1

The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex

Science ◽  
1988 ◽  
Vol 239 (4840) ◽  
pp. 586-592 ◽  
Author(s):  
R. Price ◽  
B Brew ◽  
J Sidtis ◽  
M Rosenblum ◽  
A. Scheck ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Aids Dementia Complex ◽  
Aids Dementia ◽  
The Brain ◽  
Hiv 1

scholarly journals HIV-1 tropism for the central nervous system: Brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor

Virology ◽  
2006 ◽  
Vol 346 (1) ◽  
pp. 169-179 ◽  
Author(s):  
Julio Martín-García ◽  
Wei Cao ◽  
Angel Varela-Rohena ◽  
Matthew L. Plassmeyer ◽  
Francisco González-Scarano
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Envelope Glycoproteins ◽  
Fusion Inhibitor ◽  
The Central Nervous System ◽  
Hiv 1

scholarly journals Interleukin-6 and granulocyte macrophage-csf in the cerebrospinal fluid from hiv infected subjects with involvement of the central nervous system

1992 ◽  
Vol 50 (2) ◽  
pp. 180-182 ◽  
Author(s):  
O. Perrella ◽  
M. Guerriero ◽  
E. Izzo ◽  
M. Soscia ◽  
P. B. Carrieri
Keyword(s):  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Interleukin 6 ◽  
Neurological Diseases ◽  
Aids Dementia Complex ◽  
Gm Csf ◽  
Aids Dementia ◽  
High Incidence ◽  
The Central Nervous System ◽  
Csf Levels

We detected the cytokines interleukin-6 (IL-6) and granulocyte macrophage-CSF (GM-CSF) by ELISA in the CSF and serum of 30 HIV-infected patients classified as AIDS dementia complex (ADC), and 20 subjects with other neurological diseases (OND). We have found a high incidence of detectable IL-6 and GM-CSF in the CSF of ADC patients compared with OND patients. No statistical differences were observed between both groups for serum IL-6 and GM-CSF levels. These results suggest an intrathecal synthesis of these cytokines and a possible involvement in the pathogenesis of ADC.

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