scholarly journals Periostin in the Cancer Stroma of Mycosis Fungoides Palmaris et Plantaris: A Case Report and Immunohistochemical Study

2016 ◽  
Vol 8 (1) ◽  
pp. 31-35
Author(s):  
Kayo Tanita ◽  
Taku Fujimura ◽  
Aya Kakizaki ◽  
Sadanori Furudate ◽  
Masato Mizuashi ◽  
...  
Keyword(s):  
Case Report ◽  
Mycosis Fungoides ◽  
Rare Variant ◽  
Immunohistochemical Staining ◽  
Immunohistochemical Study ◽  
Good Prognosis ◽  
Lesional Skin ◽  
Cancer Stroma ◽  
Old Japanese ◽  
M2 Phenotype

Mycosis fungoides palmaris et plantaris (MFPP) is a rare variant of mycosis fungoides limited to the palms and soles. Although little is known about the pathogenesis of MFPP, this variant of mycosis fungoides presents a relatively good prognosis. In this report, we describe an 85-year-old Japanese man with MFPP. Immunohistochemical staining revealed the dense deposition of periostin in the cancer stroma, as well as infiltration of CD163+CD206- tumor-associated macrophages (TAMs), which suggested the phenotypes of TAMs were not polarized to the M2 phenotype in the lesional skin of MFPP. Our present case might suggest one of the possible reasons for the good prognosis of MFPP.

Woringer-Kolopp Disease of the Foot: A Case Report

2020 ◽  
Vol 110 (6) ◽  
Author(s):  
James J. LaPolla ◽  
Lawrence A. DiDomenico ◽  
Robert T. Brodell ◽  
Michael L. Casteel
Keyword(s):  
Case Report ◽  
T Cell ◽  
Mycosis Fungoides ◽  
Rare Variant ◽  
Cell Lymphoma ◽  
Treatment Options ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Review Of The Literature ◽  
Intralesional Steroids

Woringer-Kolopp disease is a rare variant of mycosis fungoides, a type of cutaneous T-cell lymphoma. Described is a case of a small annular plaque on the foot diagnosed histologically as Woringer-Kolopp disease and treated successfully with topical and intralesional steroids. In addition, a brief review of the literature and treatment options is provided.

scholarly journals CD30-Positive Angioinvasive Lymphomatoid Papulosis (Type E) Developing from Parapsoriasis en Plaque

2018 ◽  
Vol 11 (3) ◽  
pp. 850-854 ◽  
Author(s):  
Taku Fujimura ◽  
Chunbing Lyu ◽  
Kenichiro Tsuchiyama ◽  
Setsuya Aiba
Keyword(s):  
Mycosis Fungoides ◽  
Rare Variant ◽  
Immunohistochemical Staining ◽  
Lymphocyte Infiltration ◽  
Lymphomatoid Papulosis

Angioinvasive lymphomatoid papulosis (LyP) type E is a rare variant characterized by angiocentric and angiodestructive features with CD30+ CD8+ lymphocyte infiltration. In rare cases, LyP type E is concomitant with mycosis fungoides, but there is no English report that describe LyP type E developing from parapsoriasis en plaque. In this report, we described a case of angioinvasive LyP (type E) developing from parapsoriasis en plaque, in which we employed immunohistochemical staining for the investigation of its pathomechanisms.

scholarly journals Sarcomatoid carcinoma a rare variant of squamous cell carcinoma of larynx: a case report

2017 ◽  
Vol 3 (3) ◽  
pp. 768
Author(s):  
Trilok C. Guleria ◽  
Shobha Mohindroo ◽  
Narender K. Mohindroo ◽  
Ramesh K. Azad
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Rare Variant ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Early Stage ◽  
Sarcomatoid Carcinoma ◽  
Spindle Cell Carcinoma ◽  
Good Prognosis

<p>Sarcomatoid (spindle cell) carcinoma is a rare variant of squamous cell carcinoma (SCC). It compromises of 2–3% of laryngeal cancers. Tumor arises from the oral cavity, tonsil, larynx and pharynx. Majority of these tumors are polypoid or pedunculated and tend to cause obstructive symptoms. These tumors are often detected at an early stage, removed by polypectomy during diagnosis and tend to have a very good prognosis. In this case report, 76 years male who presented with progressive hoarseness of his voice and pain in throat. The patient underwent direct laryngoscopy with excision of the malignant mass and received radiotherapy. </p>

Myxoid atypical fibroxanthoma: a challenging diagnosis of a rare variant: Case report

2020 ◽  
pp. 399-403
Author(s):  
Nikolina Stavrinou ◽  
Stavroula Papadopoulou ◽  
Georgia Mitropoulou ◽  
Helen Trihia ◽  
Ioannis Provatas
Keyword(s):  
Case Report ◽  
Rare Variant ◽  
Atypical Fibroxanthoma

An Obscure Colon Dilatation and its Underlying Cause: Case Report and Literature Review

2020 ◽  
pp. 1-5
Author(s):  
Anton Stift ◽  
Kerstin Wimmer ◽  
Felix Harpain ◽  
Katharina Wöran ◽  
Thomas Mang ◽  
...  
Keyword(s):  
Case Report ◽  
Sigmoid Colon ◽  
Immunohistochemical Staining ◽  
Late Onset ◽  
Hirschsprung Disease ◽  
Endoscopic Examination ◽  
Case Presentation ◽  
Idiopathic Megacolon ◽  
History Of ◽  
Cells Of Cajal

Introduction: Congenital as well as acquired diseases may be responsible for the development of a megacolon. In adult patients, Clostridium difficile associated infection as well as late-onset of Morbus Hirschsprung disease are known to cause a megacolon. In addition, malignant as well as benign colorectal strictures may lead to intestinal dilatation. In case of an idiopathic megacolon, the underlying cause remains unclear. Case Presentation: We describe the case of a 44-year-old male patient suffering from a long history of chronic constipation. He presented himself with an obscurely dilated large intestine with bowel loops up to 17 centimeters in diameter. Radiological as well as endoscopic examination gave evidence of a spastic process in the sigmoid colon. The patient was treated with a subtotal colectomy and the intraoperative findings revealed a stenotic stricture in the sigmoid colon. Since the histological examination did not find a conclusive reason for the functional stenosis, an immunohistochemical staining was advised. This showed a decrease in interstitial cells of Cajal (ICC) in the stenotic part of the sigmoid colon. Discussion: This case report describes a patient with an idiopathic megacolon, where the underlying cause remained unclear until an immunohistochemical staining of the stenotic colon showed a substantial decrease of ICCs. Various pathologies leading to a megacolon are reviewed and discussed.

Verrucous Psoriasis Successfully Treated with Ixekizumab: A Case Report with Review Literature

2020 ◽  
Vol 103 (9) ◽  
pp. 948-951
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Case Report ◽  
Rare Variant ◽  
Psoriasis Vulgaris ◽  
Review Literature ◽  
Antituberculous Therapy ◽  
Plaque Type ◽  
History Of

Verrucous psoriasis is a rare variant of plaque-type psoriasis with only about 35 cases reported. The authors reported a man with a history of psoriasis vulgaris for seven years, presented with progressive verrucous hyperkeratotic plaques on both legs for three years. His earlier investigations favored the diagnosis of tuberculosis verrucosa cutis. After completing the antituberculous therapy, the lesions persisted. The later investigations favored a rare subtype of psoriasis named verrucous psoriasis. Keywords: Verrucous psoriasis, Tuberculosis verrucosa cutis, Mycobacterium tuberculosis, Ixekixumab

Extensive Perivillous Fibrin and Intervillous Histiocytosis in a SARS-CoV-2 Infected Placenta From an Uninfected Newborn: A Case Report Including Immunohistochemical Profiling

2021 ◽  
pp. 109352662110251
Author(s):  
James Roberts ◽  
Jeanette D Cheng ◽  
Elizabeth Moore ◽  
Carla Ransom ◽  
Minhui Ma ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Immunohistochemical Staining ◽  
Placental Pathology ◽  
Fibrin Deposition ◽  
Placental Infection ◽  
Fetal Infection

Placental infection by SARS-CoV-2 with various pathologic alterations reported. Inflammatory findings, such as extensive perivillous fibrin deposition and intervillous histiocytosis, have been postulated as risk factors for fetal infection by SARS-CoV-2. We describe the placental findings in a case of a 31-year-old mother with SARS-CoV-2 infection who delivered a preterm female neonate who tested negative for SAR-CoV2 infection. Placental examination demonstrated a small for gestational age placenta with extensive intervillous histiocytosis, syncytiotrophoblast karyorrhexis, and diffuse intervillous fibrin deposition. Immunohistochemical staining demonstrated infection of the syncytiotrophoblasts by SARS-CoV-2 inversely related to the presence of intervillous histiocytes and fibrin deposition. Our case demonstrates that despite extensive placental pathology, no fetal transmission of SARS-CoV-2 occurred, as well as postulates a relationship between placental infection, inflammation, and fibrin deposition.

Sign in / Sign up

Export Citation Format

Share Document