Do Signs of Attention-Deficit/Hyperactivity Disorder Increase the Odds of Dental Caries? A Case-Control Study

2018 ◽  
Vol 52 (3) ◽  
pp. 212-219 ◽  
Author(s):  
Isabella Mota-Veloso ◽  
Isabela Almeida Pordeus ◽  
Márcio Alexandre Homem ◽  
Joana Ramos-Jorge ◽  
Fernanda Oliveira-Ferreira ◽  
...  

Attention-deficit/hyperactivity disorder (ADHD) is a behavioural disorder that can affect one’s performance in activities of daily living and can exert a negative impact on the oral health of children. Objective: The aim of this work was to determine the association between ADHD (signs and executive functions) and dental caries in children aged 7–12 years. Methods: A case-control study was conducted with 532 children in the city of Diamantina, Brazil. The case group was composed of children with caries and the control group was composed of children without caries. The children were submitted to a clinical oral examination for the determination of caries and neuropsychological evaluations of intellectual function and executive function. Other signs of attention deficit and hyperactivity were investigated using the Swanson, Nolan, and Pelham scale administered to parents/guardians and teachers. Socioeconomic and demographic characteristics were also evaluated. Statistical analysis involved the McNemar χ2 test and conditional logistic regression. Results: The multivariate logistic regression model demonstrated that monthly household income and parental reports of signs of attention deficit were significantly associated with the occurrence of dental caries. Conclusion: Children considered by their parents/guardians to have attention deficit have a greater chance of exhibiting dental caries, independently of household income.

2021 ◽  
Vol 43 (3) ◽  
pp. 260-266
Author(s):  
Nava Khalilinejad ◽  
Leila Mehdizadeh Fanid ◽  
Narges Zeinalzadeh ◽  
Maedeh Alizadeh

Background: Attention deficit hyperactivity disorder (ADHD) is the most common and highly heritable psychiatric disorder among children which affects 3-7% of them all around the world. ADHD characterized by some symptoms such as extreme and inappropriate levels of motor activity, impulsivity and inattentiveness. Several studies have reported the association between dopaminergic pathway and ADHD. Dopamine D4 receptor gene and its variants is one of the major candidates that have been studied for ADHD. Here we investigated the genetic association between DRD4 rs1800955 polymorphism and ADHD among children from Northwest of Iran. Methods: This case-control study includes 200 ADHD children and 157 controls aged 6-12 years. ADHD children were diagnosed according to DSM-IV and Conners scale and were genotyped by PCR-Restriction fragment length polymorphism (RFLP) technique. Results: Frequencies of genotypes CC, TT and CT were 48 (24%), 15 (7.5%) and 137 (68.5%) in patient group and 50 (31.85% %), 7 (4.46%) and 100 (63.69 %) in control group respectively. According to results, there was no significant association between case and control groups (p>0.05). Conclusion: The results of this study indicate that there is no significant association between DRD4 rs1800955 polymorphism and attention deficit hyperactivity disorder among children from Northwest of Iran.


2020 ◽  
Vol 27 (1) ◽  
Author(s):  
Noran Abd-Elmoneim ◽  
Eman Elsheshtawy ◽  
Mohamed Elsayed ◽  
Zeinab Gomaa ◽  
Mahmoud Elwasify

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