scholarly journals Long-Term Survival of Two Patients with Liver Metastases from Advanced Gastric Cancer Treated with Radiofrequency Ablation and Chemotherapy

2021 ◽  
pp. 67-72
Author(s):  
Sung Jin Oh
Keyword(s):  
Gastric Cancer ◽  
Radiofrequency Ablation ◽  
Liver Metastases ◽  
Advanced Gastric Cancer ◽  
Systemic Chemotherapy ◽  
Subtotal Gastrectomy ◽  
Hepatic Metastases ◽  
Term Survival ◽  
Long Term Survival

Liver metastasis from gastric cancer has a very poor prognosis. Herein, we present two cases of liver metastases (synchronous and metachronous) from advanced gastric cancer. In the first case, the patient underwent radical subtotal gastrectomy. Liver metastases occurred 6 months after surgery while the patient was receiving adjuvant chemotherapy, but two hepatic tumors were successfully removed by radiofrequency ablation (RFA). In the second case, liver metastases occurred 15 months after surgery for gastric cancer. The patient also received RFA for one hepatic tumor, and other suspicious metastatic tumors were treated with systemic chemotherapy. Although these case presentations are limited for the efficacy of RFA treatment with systemic chemotherapy for hepatic metastases from gastric cancer, our findings showed long-term survival (overall survival for 108 and 67 months, respectively) of the affected patients, without recurrence. Therefore, we suggest that RFA treatment with systemic chemotherapy could be an effective alternative treatment modality for hepatic metastases from gastric cancer.

scholarly journals Multiorgan resection in patients with gastric cancer

2004 ◽  
Vol 57 (9-10) ◽  
pp. 480-486 ◽  
Author(s):  
Dragan Radovanovic ◽  
Dejan Stevanovic ◽  
Ivan Pavlovic ◽  
Aleksandar Bajec ◽  
Berislav Vekic ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Advanced Gastric Cancer ◽  
Subtotal Gastrectomy ◽  
Postoperative Mortality ◽  
Control Group ◽  
Term Survival ◽  
Long Term Survival ◽  
Systematic Lymphadenectomy

Introduction Multiorgan resection for a malignancy is a very comlicated procedure, but there is always the question: does it work? In everyday clinical practice gastric cancer in phases III and IV is rather frequent. Unfortunately, our patients are under the age of 55 years. D2 lymphadenectomy is not as extensive as D2 %/ or D3, so one must ask himself if multiorgan resection is worth the risk. Material and methods We evaluated two groups of patients: group I consisted of 34 patients who underwent total or subtotal gastrectomy, systematic lymphadenectomy and resection of one or more organs; group II (control) consisted of 167 patients who underwent total or subtotal gastrectomy and systematic lymphadenectomy. These two groups of patients were analzyed in regard to: Bormann's classification, histopathologic type, early mortality, early postoperative complications, lymph node dissection and long-term survival. Results According to Bormann's classification the most common type of carcinoma in both groups was ulcerovegetativ tumor (70.6% in I and 58% in II). In the first group of patients a great number of patients had poorly differentiated adenocarcinomas (47%), while in the second group the most common histologic type was well differentiated intestinal carcinoma (28%). Patients with multiorgan resections had higher rates of early postoperative mortality and morbiditiy (mortality - 14.7% and complications - 26.5%) than patients in control group (mortality - 4.8% and complications - 11.4%). The most frequent causes of postopertive mortality and morbidity were anastomotic leakage and wound infections in both groups. Metastatic lymph node invelvement was higher in the first group (41%), than in the second (28%). Long-term survival was best in the control group (38.5 months). Patients with multiorgan resection had better survival (25.4 months) than inoperable cases (only 5 months). Discussion Patients undergoing multiorgan resection usually have advanced gastric cancer with tumor infiltration in surrounding structures. Only these cases are absolute indications for this radical operation, because patients have better chances fo survival. Conclusion Multiorgan resections are extensive procedures with high rates of postoperative mortality and morbiditiy, but represent the only way for better survival of patients with advanced gastric cancer.

scholarly journals A Case of Noncuratively Resected Gastric Cancer and Postoperative Chemotherapy with S-1 Monotherapy Resulting in Long-Term Survival for Over 8 Years

2017 ◽  
Vol 10 (1) ◽  
pp. 217-225
Author(s):  
Byoung Jo Suh
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Subtotal Gastrectomy ◽  
Term Survival ◽  
Long Term Survival ◽  
Positron Emission ◽  
Term Administration ◽  
Pancreatic Invasion ◽  
Resected Gastric Cancer

We report the case of a noncuratively resected gastric cancer patient who was successfully treated with S-1 monotherapy, resulting in long-term survival of 96 months. A 72-year-old woman underwent noncurative resection of subtotal gastrectomy for advanced gastric cancer with conglomerated lymph node metastasis and pancreatic invasion. She received chemotherapy with S-1 monotherapy postoperatively. S-1 (100 mg/day) was administered orally after breakfast and dinner for 28 days followed by a 14-day break for a total of 52 months. Regular checkups with esophagogastroduodenoscopy, abdominopelvic computed tomography, and fluorine-18-fluorodeoxyglucose positron emission tomography revealed no evidence of cancer 96 months after the operation. The patient was effectively treated with long-term administration of S-1 after noncurative gastrectomy for advanced gastric cancer.

Adjuvant chemotherapy enhances long-term survival of patients with advanced gastric cancer following curative resection

1990 ◽  
Vol 45 (3) ◽  
pp. 169-172 ◽  
Author(s):  
Yoshihiko Maehara ◽  
Sunao Moriguchi ◽  
Yoshihisa Sakaguchi ◽  
Yasunori Emi ◽  
Shunji Kohnoe ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Advanced Gastric Cancer ◽  
Curative Resection ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Surgical resection of metachronous hepatic metastases from gastric cancer improves long-term survival: A population-based study

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0182255 ◽  
Author(s):  
Szu-Chin Li ◽  
Cheng-Hung Lee ◽  
Chung-Lin Hung ◽  
Jin-Chia Wu ◽  
Jian-Han Chen
Keyword(s):  
Gastric Cancer ◽  
Surgical Resection ◽  
Hepatic Metastases ◽  
Population Based ◽  
Term Survival ◽  
Population Based Study ◽  
Long Term Survival

scholarly journals Breast Cancer Liver Metastases: US-guided Percutaneous Radiofrequency Ablation—Intermediate and Long-term Survival Rates

Radiology ◽  
2009 ◽  
Vol 253 (3) ◽  
pp. 861-869 ◽  
Author(s):  
Maria Franca Meloni ◽  
Anita Andreano ◽  
Paul F. Laeseke ◽  
Tito Livraghi ◽  
Sandro Sironi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Radiofrequency Ablation ◽  
Liver Metastases ◽  
Survival Rates ◽  
Percutaneous Radiofrequency Ablation ◽  
Term Survival ◽  
Long Term Survival ◽  
Breast Cancer Liver Metastases

scholarly journals A Case of Two Resections for Metachronous Liver Metastases of Gastric Cancer: A Case Report and Review of the Literature

2018 ◽  
Vol 1 (1) ◽  
pp. 01-06
Author(s):  
Ishibashi Yusuke ◽  
Tsujimoto Hironori ◽  
Yamamoto Junji ◽  
Ueno Hideki
Keyword(s):  
Gastric Cancer ◽  
Liver Metastases ◽  
Surgical Resection ◽  
Vena Cava ◽  
Term Survival ◽  
Case Presentation ◽  
Long Term Survival ◽  
Solitary Metastases ◽  
Selection Of

Background: The clinical significance of surgical resection for liver metastases of gastric cancer remains controversial. Herein, we report a case of twice resections for metachronous liver metastases of gastric cancer in combination with perioperative chemotherapy, which resulted in long-term survival. Case Presentation: The patient was a 66-year-old man who underwent laparoscopic total gastrectomy for gastric cancer (Stage IB) in March 2012, and subsequently underwent right hemi-hepatectomy with partial resection of the vena cava and diaphragm for solitary metastases in segments 7-8 in April 2013. In September 2013, abdominal computed tomography detected a liver metastasis in segment 4. We administered systematic chemotherapy with S-1 plus cis-diamminedichloroplatinum (CDDP). Because the tumor decreased in size after five courses, and curative resection of the tumor was considered possible, hepatic resection of S4+1 was performed in June 2014. The patient has been followed for 26 months, and, after the last hepatectomy, had no evidence of recurrence.Conclusion: We experienced a case of long-term survival after twice resections for liver metastases from gastric cancer. Surgical resection for liver metastases of gastric cancer, even repeat hepatectomy, may be an effective treatment after careful selection of the optimal candidate.

Sign in / Sign up

Export Citation Format

Share Document