scholarly journals Smoking and Periodontitis Can Play a Synergistic Role in the Development of Psoriasis: A Nationwide Cohort Study

Dermatology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Ju Hee Han ◽  
Jin Woo Park ◽  
Kyung Do Han ◽  
Jun Beom Park ◽  
Miri Kim ◽  
...  
Keyword(s):  
Multivariable Analysis ◽  
Population Based ◽  
Inflammatory Disorder ◽  
National Health Insurance System ◽  
Population Based Study ◽  
Chronic Inflammatory Disorder ◽  
Korean National Health Insurance ◽  
The Relationship ◽  
Increase In Risk

<b><i>Background:</i></b> Periodontitis is a chronic inflammatory disorder involving the periodontium. The precise nature of the association between periodontitis and psoriasis has not been determined. <b><i>Objective:</i></b> This nationwide population-based study investigated the relationship between periodontitis and the risk of psoriasis. <b><i>Methods:</i></b> A health screening database, which is a sub-dataset of the Korean National Health Insurance System database, was used in this study. Subjects with (<i>n</i> = 1,063,004) and without (<i>n</i> = 8,655,587) periodontitis who underwent health examinations from January to December 2009 were followed for 9 years. <b><i>Results:</i></b> In multivariable analysis, compared to the non-periodontitis group, periodontitis patients had a significantly higher risk of developing psoriasis (hazard ratio 1.116, 95% confidence interval 1.101–1.13). Non-smokers with periodontitis had an 11% increase in risk of psoriasis and smokers with periodontitis had a 26.5% increase in risk of psoriasis compared to non-smokers without periodontitis. <b><i>Conclusion:</i></b> Our study highlights periodontitis as a potential independent risk factor for psoriasis, increasing awareness of the synergistic role of smoking and periodontitis in the pathogenesis of psoriasis.

scholarly journals Clinical Efficacy of Ruxolitinib in Patients with Myelofibrosis: A Nationwide Population-Based Study in Korea

2021 ◽  
Vol 10 (20) ◽  
pp. 4774
Author(s):  
Byung-Hyun Lee ◽  
Hyemi Moon ◽  
Jae-Eun Chae ◽  
Ka-Won Kang ◽  
Byung-Soo Kim ◽  
...  
Keyword(s):  
Propensity Scores ◽  
Cox Regression ◽  
Multivariable Analysis ◽  
Previous History ◽  
Population Based ◽  
Population Based Study ◽  
Cox Regression Analysis ◽  
History Of ◽  
Korean National Health Insurance ◽  
Insurance Database

Previous studies have reported the survival benefit after ruxolitinib treatment in patients with myelofibrosis (MF). However, population-based data of its efficacy are limited. We analyzed the effects of ruxolitinib in MF patients with data from the Korean National Health Insurance Database. In total, 1199 patients diagnosed with MF from January 2011 to December 2017 were identified, of which 731 were included in this study. Patients who received ruxolitinib (n = 224) were matched with those who did not receive the drug (n = 507) using the 1:1 greedy algorithm. Propensity scores were formulated using five variables: age, sex, previous history of arterial/venous thrombosis, and red blood cell (RBC) or platelet (PLT) transfusion dependence at the time of diagnosis. Cox regression analysis for overall survival (OS) revealed that ruxolitinib treatment (hazard ratio (HR), 0.67; p = 0.017) was significantly related to superior survival. In the multivariable analysis for OS, older age (HR, 1.07; p < 0.001), male sex (HR, 1.94; p = 0.021), and RBC (HR, 3.72; p < 0.001) or PLT (HR, 9.58; p = 0.001) transfusion dependence were significantly associated with poor survival, although type of MF did not significantly affect survival. Considering evidence supporting these results remains weak, further studies on the efficacy of ruxolitinib in other populations are needed.

scholarly journals The Relationship between Aeroallergen Sensitization and Chronic Cough in School-Aged Children from General Population

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Myongsoon Sung ◽  
Dong Keon Yon ◽  
Seung Won Lee ◽  
Ju Hee Kim ◽  
Hey Sung Baek ◽  
...  
Keyword(s):  
Chronic Cough ◽  
Multivariable Analysis ◽  
Allergic Diseases ◽  
Population Based ◽  
Population Based Study ◽  
Current Smoking ◽  
School Aged Children ◽  
Increased Risk ◽  
Skin Prick Tests ◽  
The Relationship

Objective. Determining sensitivity to allergens is an essential step in diagnosing children with allergic diseases. Chronic cough has remained poorly understood with causative triggers. The purpose of our study was to shed light on the relationship between sensitization to aeroallergens and chronic cough. Methods. This population-based study examined children (aged 7 years to 13 years) between June and July 2016. The 1,259 children, 72 of whom (5.7%) had a chronic cough, and 1,187 of whom (94.3%) did not (controls), completed the questionnaire, but 1,051 children completed skin prick tests (SPTs) with eight aeroallergens. Results. There were positive SPT results to at least 1 allergen in 549 children (52.2%). Sensitization to house dust mite (HDM) was most common (chronic cough = 46.9 % ; controls = 47.2 % ), followed by pollen (chronic cough = 21.9 % ; controls = 16.5 % ) in both groups, but there was no difference in allergic profile and sensitization to aeroallergen ( P > 0.05 for all comparisons). Multivariable analysis with adjustment for confounding indicated that children who were in sensitization to pollen had an increased risk of chronic cough ( aOR = 2.387 ; 95% CI: 1.115 to 5.111; P = 0.025 ). Multivariable analysis with adjustment for confounding indicated that children who were exposed to current smoking ( aOR = 4.442 ; 95% CI: 1.831 to 10.776; P = 0.001 ) and mold ( aOR = 1.988 ; 95% CI: 1.168 to 3.383; P = 0.011 ) were associated with chronic cough. Conclusion. Sensitization to pollen should be considered as a potential contributing factor to the development of chronic cough in school-aged children.

scholarly journals Socioeconomic status associated with carpal tunnel syndrome: A retrospective nationwide 11-year population-based cohort study in South Korea

2018 ◽  
Author(s):  
Hong-Jae Lee ◽  
Hyun Sun Lim ◽  
Hyoung Seop Kim
Keyword(s):  
Socioeconomic Status ◽  
Cohort Study ◽  
Population Based ◽  
Lower Socioeconomic Status ◽  
National Health Insurance System ◽  
Hazard Ratios ◽  
Lower Socioeconomic ◽  
Korean National Health Insurance ◽  
Tunnel Syndrome ◽  
The Relationship

AbstractImportanceThere have only been a few large-scale studies that have included a risk factor analysis for CTS. No prior study has investigated the relationship between the occurrence of CTS and stratified socioeconomic status, which is closely related to a person’s type of job.ObjectiveTo confirm the known risk factors for CTS and also to determine the correlation between stratified socioeconomic status and the occurrence of CTS.DesignWe conducted this study using a retrospective cohort model based on the combined databases of the Korean National Health Insurance System from 2003–2013, a database compiled using information from a national periodic health-screening program that is used for reimbursement claims.SettingThe setting was a population-based retrospective cohort study.ParticipantsFirst, we randomly sampled 514,795 patients who represented 10% of the 5,147,950 people who took part in periodic health screenings from 2002–2003. Existing CTS patients were excluded from this group. Therefore, this study finally included 512,942 participants and followed their medical records from 2003–2013.Main Outcomes and MeasuresDesired outcomes were the incidence rate of CTS and the hazard ratios according to stratified socioeconomic status.ResultsA correlation analysis showed that CTS was more likely to occur in patients from a lower socioeconomic status.Conclusions and RelevanceCTS was associated with people of a lower socioeconomic status who work in simple but repetitive manual labor jobs. We believe that the results of our study will be helpful to determine the pathophysiology of CTS and to set up a new industrial health policy for this condition.Key PointsQuestionWhat is the relationship between stratified socioeconomic status and the incidence of carpal tunnel syndrome (CTS)?FindingsIn this retrospective population-based cohort study that included 512,942 participants sampled from the Korean National Health Insurance System(KNHIS) database, the incidence rate and hazard ratios for CTS tended to increase with lower socioeconomic status.ImplicationsLow socioeconomic status was identified as a risk factor for the incidence of CTS.

Does the relationship between 25-hydroxyvitamin D status and bone mass vary according to skin color in adults? Results of a Brazilian population-based study

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Kátia Josiany Segheto ◽  
Leidjaira Lopes Juvanhol ◽  
Danielle Cristina Guimarães da Silva ◽  
Cristiane Junqueira de Carvalho ◽  
Fernanda Hansen ◽  
...  
Keyword(s):  
Bone Mass ◽  
Skin Color ◽  
Population Based ◽  
Brazilian Population ◽  
Population Based Study ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
The Relationship

The relationship between suicide risk and sexual orientation: Results of a population-based study

1996 ◽  
Vol 18 (2) ◽  
pp. 123 ◽  
Author(s):  
Gary Remafedi ◽  
Simone French ◽  
Mary Story ◽  
MichaelD. Resnick ◽  
Robert Blum
Keyword(s):  
Sexual Orientation ◽  
Suicide Risk ◽  
Population Based ◽  
Population Based Study ◽  
The Relationship

The relationship between economic conditions and postpartum depression in Taiwan: a nationwide population-based study

2016 ◽  
Vol 204 ◽  
pp. 174-179 ◽  
Author(s):  
Fung-Wei Chang ◽  
Wen-Ying Lee ◽  
Yueh-Ping Liu ◽  
Jing-Jung Yang ◽  
Shu-Pin Chen ◽  
...  
Keyword(s):  
Postpartum Depression ◽  
Population Based ◽  
Economic Conditions ◽  
Population Based Study ◽  
The Relationship

scholarly journals The role of giving and receiving emotional support in depressive symptomatology among older couples: An application of the actor-partner interdependence model

2010 ◽  
Vol 28 (1) ◽  
pp. 83-99 ◽  
Author(s):  
Linda K. Ko ◽  
Megan A. Lewis
Keyword(s):  
Emotional Support ◽  
Depressive Symptomatology ◽  
Population Based ◽  
Path Model ◽  
The Other ◽  
Older Couples ◽  
Actor Partner Interdependence Model ◽  
The Relationship

The present study investigated whether perception of receiving emotional support mediates the relationship between one partner’s giving of emotional support and the other partner’s depressive symptomatology using a population-based sample of 423 couples from the Changing Lives of Older Couples study. A path model was used guided by the Actor—Partner Interdependence Model. Results indicated that spouses’ giving emotional support was related to the degree to which their spouse reported receiving emotional support. Perception of receiving emotional support, in turn, was related to lower depressive symptomatology of the support recipient. Both husbands and wives can benefit from emotional support through their perception of receiving emotional support, and spouses’ perceptions, as well as their actions, should be considered in support transactions.

The relationship between body weight and drug costs: An Italian population-based study

2006 ◽  
Vol 28 (9) ◽  
pp. 1472-1481 ◽  
Author(s):  
Ezio Degli Esposti ◽  
Alessandra Sturani ◽  
Giorgia Valpiani ◽  
Mirko Di Martino ◽  
Francesco Ziccardi ◽  
...  
Keyword(s):  
Body Weight ◽  
Population Based ◽  
Drug Costs ◽  
Italian Population ◽  
Population Based Study ◽  
The Relationship

Willingness to cooperate with police: A population-based study of Australian young adult illicit stimulant users

2016 ◽  
Vol 17 (3) ◽  
pp. 301-318 ◽  
Author(s):  
Ellen M Leslie ◽  
Adrian Cherney ◽  
Andrew Smirnov ◽  
Helene Wells ◽  
Robert Kemp ◽  
...  
Keyword(s):  
Young Adult ◽  
Procedural Justice ◽  
Drug Users ◽  
Illicit Drug ◽  
Population Based ◽  
Police Legitimacy ◽  
Population Based Study ◽  
Reduction Strategies ◽  
Willingness To Cooperate

While procedural justice has been highlighted as a key strategy for promoting cooperation with police, little is known about this model’s applicability to subgroups engaged in illegal behaviour, such as illicit drug users. This study compares willingness to cooperate with police and belief in police legitimacy, procedural justice and law legitimacy among a population-based sample of Australian young adult amphetamine-type stimulant (ATS; i.e. ecstasy and methamphetamine) users and non-users. We then examine predictors of willingness to cooperate among ATS users. ATS users were significantly less willing to cooperate with police and had significantly lower perceptions of police legitimacy, procedural justice and law legitimacy, compared to non-users. However, belief in police legitimacy independently predicted willingness to cooperate among ATS users. We set out to discuss the implications of these findings for policing, including the role of procedural justice in helping police deliver harm reduction strategies.

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