scholarly journals Socioeconomic status associated with carpal tunnel syndrome: A retrospective nationwide 11-year population-based cohort study in South Korea

2018 ◽  
Author(s):  
Hong-Jae Lee ◽  
Hyun Sun Lim ◽  
Hyoung Seop Kim

AbstractImportanceThere have only been a few large-scale studies that have included a risk factor analysis for CTS. No prior study has investigated the relationship between the occurrence of CTS and stratified socioeconomic status, which is closely related to a person’s type of job.ObjectiveTo confirm the known risk factors for CTS and also to determine the correlation between stratified socioeconomic status and the occurrence of CTS.DesignWe conducted this study using a retrospective cohort model based on the combined databases of the Korean National Health Insurance System from 2003–2013, a database compiled using information from a national periodic health-screening program that is used for reimbursement claims.SettingThe setting was a population-based retrospective cohort study.ParticipantsFirst, we randomly sampled 514,795 patients who represented 10% of the 5,147,950 people who took part in periodic health screenings from 2002–2003. Existing CTS patients were excluded from this group. Therefore, this study finally included 512,942 participants and followed their medical records from 2003–2013.Main Outcomes and MeasuresDesired outcomes were the incidence rate of CTS and the hazard ratios according to stratified socioeconomic status.ResultsA correlation analysis showed that CTS was more likely to occur in patients from a lower socioeconomic status.Conclusions and RelevanceCTS was associated with people of a lower socioeconomic status who work in simple but repetitive manual labor jobs. We believe that the results of our study will be helpful to determine the pathophysiology of CTS and to set up a new industrial health policy for this condition.Key PointsQuestionWhat is the relationship between stratified socioeconomic status and the incidence of carpal tunnel syndrome (CTS)?FindingsIn this retrospective population-based cohort study that included 512,942 participants sampled from the Korean National Health Insurance System(KNHIS) database, the incidence rate and hazard ratios for CTS tended to increase with lower socioeconomic status.ImplicationsLow socioeconomic status was identified as a risk factor for the incidence of CTS.

2009 ◽  
Vol 21 (4) ◽  
pp. 487-496 ◽  
Author(s):  
Charumathi Sabanayagam ◽  
Anoop Shankar ◽  
Seang Mei Saw ◽  
E. Shyong Tai ◽  
Tien Yin Wong

In developed countries in the West, lower socioeconomic status (SES) is associated with a higher prevalence of overweight/obesity. The authors examined the association between SES defined by education and income and overweight/obesity in a population-based cohort of 2807 individuals of Malay ethnicity (age 40-80 years, 51% women) in Singapore. The prevalence of overweight/ obesity (body mass index ≥25 kg/m2) in men and women was 50.4% and 65.1%, respectively. In women, the prevalence of overweight/obesity increased with lower levels of education and income. Compared with the higher categories of SES, the odds ratio (95% confidence interval) of overweight/obesity in women was 1.42 (1.06-1.89) for education and 2.08 (1.33-3.26) for income. In contrast, in men, the prevalence of overweight/obesity decreased with lower levels of education and income ( P interaction by gender <.05 for all SES variables). Lower SES was positively associated with overweight/obesity in Malay women, and the association was in the opposite direction in Malay men.


2018 ◽  
Vol 68 (669) ◽  
pp. e245-e251 ◽  
Author(s):  
Anna Cassell ◽  
Duncan Edwards ◽  
Amelia Harshfield ◽  
Kirsty Rhodes ◽  
James Brimicombe ◽  
...  

BackgroundMultimorbidity places a substantial burden on patients and the healthcare system, but few contemporary epidemiological data are available.AimTo describe the epidemiology of multimorbidity in adults in England, and quantify associations between multimorbidity and health service utilisation.Design and settingRetrospective cohort study, undertaken in England.MethodThe study used a random sample of 403 985 adult patients (aged ≥18 years), who were registered with a general practice on 1 January 2012 and included in the Clinical Practice Research Datalink. Multimorbidity was defined as having two or more of 36 long-term conditions recorded in patients’ medical records, and associations between multimorbidity and health service utilisation (GP consultations, prescriptions, and hospitalisations) over 4 years were quantified.ResultsIn total, 27.2% of the patients involved in the study had multimorbidity. The most prevalent conditions were hypertension (18.2%), depression or anxiety (10.3%), and chronic pain (10.1%). The prevalence of multimorbidity was higher in females than males (30.0% versus 24.4% respectively) and among those with lower socioeconomic status (30.0% in the quintile with the greatest levels of deprivation versus 25.8% in that with the lowest). Physical–mental comorbidity constituted a much greater proportion of overall morbidity in both younger patients (18–44 years) and those patients with a lower socioeconomic status. Multimorbidity was strongly associated with health service utilisation. Patients with multimorbidity accounted for 52.9% of GP consultations, 78.7% of prescriptions, and 56.1% of hospital admissions.ConclusionMultimorbidity is common, socially patterned, and associated with increased health service utilisation. These findings support the need to improve the quality and efficiency of health services providing care to patients with multimorbidity at both practice and national level.


2018 ◽  
Author(s):  
Hong-Jae Lee ◽  
Hyun Sun Lim ◽  
Hyoung Seop Kim

AbstractKey PointsQuestionWhat is the relationship between the previously known risk factors and occurrence of carpal tunnel syndrome (CTS)?FindingsIn this retrospective population-based cohort study that included 512,942 participants sampled from the Korean National Health Insurance System database, we determined the following known risk factors were related to the occurrence of CTS: the age of 40s, female, being overweight, diabetes, rheumatoid arthritis, gout, and Raynaud’s syndrome. However, ESRD, hypothyroidism and smoking were not correlated with CTS occurrence.ImplicationsWe identified the age of 40s, female, overweight, diabetes, rheumatoid arthritis, gout, and Raynaud’s syndrome as risk factors for the occurrence of CTS.AbstractImportanceThere have been few large-scale studies that have included a risk factor analysis for CTS. No prior study has investigated and validated the relationship between the occurrence of CTS and known risk factors using nationwide health care database.ObjectiveTo confirm the actual risk factors for CTS out of various known risk factorsDesignWe conducted this study using a retrospective cohort model based on the combined two databases of the Korean National Health Insurance System; the national periodic health screening program database from 2002–2003 and health insurance database of reimbursement claims from 2003 through 2013.SettingA population-based retrospective cohort study.ParticipantsFirst, we randomly sampled 514,795 patients who represented 10% of the 5,147,950 people who took part in periodic health screenings in 2002–2003. Existing CTS patients were excluded from this group. Therefore, this study finally included 512,942 participants and followed up their medical records from 2003–2013.Main Outcomes and MeasuresDesired outcomes were the incidence rate of CTS in patients with various risk factors and the hazard ratios of risk factors affecting the disease’s occurrence.ResultsThe incidence of CTS was highest in patients in the age of 40s, in the moderate obesity group, in females, and in patients with diabetes mellitus (DM). The hazard ratio analysis revealed that the following risk factors were strongly related to the occurrence of CTS: age of 40s, female, obesity, DM, rheumatoid arthritis, gout, and Raynaud’s syndrome. However, ESRD, hypothyroidism and smoking were not correlated with CTS occurrence.Conclusions and RelevanceIn our large-scale cohort study, risk factors such as being in one’s 40s, obesity, being female, suffering from DM, and rheumatoid arthritis were reaffirmed as those of CTS occurrence.


Dermatology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Ju Hee Han ◽  
Jin Woo Park ◽  
Kyung Do Han ◽  
Jun Beom Park ◽  
Miri Kim ◽  
...  

<b><i>Background:</i></b> Periodontitis is a chronic inflammatory disorder involving the periodontium. The precise nature of the association between periodontitis and psoriasis has not been determined. <b><i>Objective:</i></b> This nationwide population-based study investigated the relationship between periodontitis and the risk of psoriasis. <b><i>Methods:</i></b> A health screening database, which is a sub-dataset of the Korean National Health Insurance System database, was used in this study. Subjects with (<i>n</i> = 1,063,004) and without (<i>n</i> = 8,655,587) periodontitis who underwent health examinations from January to December 2009 were followed for 9 years. <b><i>Results:</i></b> In multivariable analysis, compared to the non-periodontitis group, periodontitis patients had a significantly higher risk of developing psoriasis (hazard ratio 1.116, 95% confidence interval 1.101–1.13). Non-smokers with periodontitis had an 11% increase in risk of psoriasis and smokers with periodontitis had a 26.5% increase in risk of psoriasis compared to non-smokers without periodontitis. <b><i>Conclusion:</i></b> Our study highlights periodontitis as a potential independent risk factor for psoriasis, increasing awareness of the synergistic role of smoking and periodontitis in the pathogenesis of psoriasis.


PEDIATRICS ◽  
1992 ◽  
Vol 89 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Fernando D. Martinez ◽  
Martha Cline ◽  
Benjamin Burrows

The relationship between parental smoking and both subsequent development of asthma and subsequent lung function (before age 12) was studied in more than 700 children enrolled before age 5. Children of mothers with 12 or fewer years of education and who smoked 10 or more cigarettes per day were 2.5 times more likely (95% confidence interval 1.42 to 4.59; P = .0018) to develop asthma and had 15.7% lower maximal midexpiratory flow (P &lt; .001) than children of mothers with the same education level who did not smoke or smoked fewer than 10 cigarettes per day. These relationships were independent of self-reported respiratory symptoms in parents. There was no association between maternal smoking and subsequent incidence of asthma or maximal midexpiratory flow among children of mothers with more than 12 years of education. It is concluded that children of lower socioeconomic status may be at considerable risk of developing asthma if their mothers smoke 10 or more cigarettes per day. It is speculated that recently reported increases in prevalence of childhood asthma may be in part related to the increased prevalence of smoking among less educated women.


Open Medicine ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. 511-522 ◽  
Author(s):  
Attila Vereczkey ◽  
Zsolt Kósa ◽  
Melinda Csáky-Szunyogh ◽  
Róbert Urbán ◽  
Andrew Czeizel

AbstractThe objective of our project is to reveal the possible etiological factors of different congenital cardiovascular abnormalities. In this study, we evaluated single ventricular septal defect (VSD) after surgical correction or with lethal outcome. The birth outcomes of these cases in the function of maternal socio-demographic features were evaluated. Data are based on 1,659 VSD cases, 2,534 matched controls and 38,151 all controls without any defects, in addition in the mothers of 19,393 malformed controls with other isolated defects in the population-based large dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities. VSD had mild female excess with a higher rate of preterm birth and mainly low birth weight indicating intrauterine growth restriction of affected fetuses, particularly in males and full-term or average weighted cases. The mothers of cases with VSD had lower socioeconomic status and higher rate of smoking and particularly drinking habit. The evaluation of medically recorded pregnancy complications showed an association of gestational diabetes with a higher risk of VSD. In conclusion, the association of small localized size of VDS and obvious fetal growth restriction needs further explanation in these cases, while gestational diabetes, lower socioeconomic status and adverse lifestyle of pregnant women may have a role in the origin of VSD.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jin-Yi Hsu ◽  
Peter Pin-Sung Liu ◽  
An-Bang Liu ◽  
Huei-Kai Huang ◽  
Ching-Hui Loh

AbstractPatients with hepatocellular carcinoma (HCC) might be more vulnerable to develop stroke than other cancer patients because of HCC-associated coagulation dysfunction. However, limited studies have investigated the relationship between HCC and stroke. This nationwide population-based cohort study enrolled all patients with HCC diagnosed between 2011 and 2015 from the Taiwan Cancer Registry and Taiwan National Health Insurance Research Database; an age- and sex-matched cohort without cancer was included. The primary outcome was the 1-year risk for first-ever stroke after the index date. The Fine and Gray competing risk regression model was used to estimate the 1-year stroke risk with adjusted hazard ratios (aHRs). After propensity score matching, each cohort has 18,506 patients with similar baseline characteristics. Compared with the cancer-free cohort, the aHRs in the HCC cohort for overall, ischemic, and hemorrhagic strokes were 1.59 [95% confidence interval (CI), 1.35–1.88], 1.38 [95% CI, 1.15–1.65], and 2.62 [95% CI, 1.79–3.84], respectively. On subgroup analysis, HCC patients without cirrhosis, those with stage 3 or 4 cancer had a higher stroke risk than cancer-free cohort. Therefore, stroke prevention should be considered in patients with HCC, especially in those without cirrhosis and with stage 3 or 4 cancer.


2017 ◽  
Vol 1 (4) ◽  
pp. 131-131
Author(s):  
Ali Dadashi ◽  
Saeed Eslami ◽  
Mohamad Reza Kalani

Introduction: Emergency medical events are not randomly distributed over a certain area. Many hidden patterns may influence this distribution due to several socioeconomic, demographic, and geospatial factors. Identifying these patterns will help health policy makers have a better planning for emergency medical services (EMS) in finding high-risk places, and people at high risk. Methods: Mashhad city EMS calls records have been analyzed retrospectively. The privacy of the data was considered by eliminating the identification information such as the name or phone number of the patients. To recognize the location of the requests all the recorded addresses were mapped into a single number representing the municipality region of the address. To express the relationship between the predictors, correlation coefficient has been employed.   Results: 154528 calls in a citywide registry from March 21, 2013, to March 20, 2014, were investigated. The average of age was 42.43 years (S.D = 21.7) with 50.5% male, 40.7% female and 8.8% of the sex were not registered. 64% of the calls were medical related and the remaining 36% were trauma-related requests. Aside from traffic accident that was the top most in all regions, other top five reasons for ambulance request including weakness, seizure, unconsciousness, nervous stress, and dyspnea were recognized. Although the regions with lower socioeconomic status are more vulnerable, they request ambulances less frequently than the regions with higher socioeconomic status. Conclusion: There is a relationship between the socioeconomic status of people and their calls to EMS. The results of this study can help policymakers in finding people in potentially high-risk locations and provide facilities to reduce mortality and morbidity.


2018 ◽  
Vol 6 (5) ◽  
pp. 735-743 ◽  
Author(s):  
David Dodell-Feder ◽  
Laura Germine

Social anhedonia (SA)—reduced drive for and pleasure from social interaction—is associated with social/emotional dysfunction and risk for psychopathology. However, our understanding of the factors that contribute to variation in SA remains limited. Here, we investigate the epidemiology of SA in an international population-based sample of more than 19,000 individuals who completed the Revised Social Anhedonia Scale through TestMyBrain.org . We find that SA exhibits considerable variation over the life span and is higher in males versus females, people of lower socioeconomic status, those of African ethnicity, nonmigrants, and people living in ethnically dense locations and less urban environments. Gender, socioeconomic status, and urbanicity were the only factors that captured unique variance in SA. These findings provide a framework for understanding how variation in epidemiological factors contribute to variation in elemental building blocks of psychopathology, and demonstrate the utility of using big data approaches toward the study of risk and Research Domain Criteria dimensions.


2019 ◽  
Vol 104 (11) ◽  
pp. 5633-5641 ◽  
Author(s):  
Seung-Hwan Lee ◽  
Hun-Sung Kim ◽  
Yong-Moon Park ◽  
Hyuk-Sang Kwon ◽  
Kun-Ho Yoon ◽  
...  

Abstract Context The bidirectional relationship between low high-density lipoprotein cholesterol (HDL-C) and glucose intolerance is well established. Recent studies suggested an association of lipid variability with various health outcomes. Objective To investigate the combined effect of HDL-C levels and their variability on the risk of diabetes. Design A population-based cohort study. Setting and Participants In all, 5,114,735 adults without known diabetes in the Korean National Health Insurance System cohort who underwent three or more health examinations from 2009 to 2013 were included. Visit-to-visit HDL-C variability was calculated using variability independent of the mean (VIM) and the coefficient of variation (CV). Low mean and high variability groups were defined as the lowest and highest quartiles of HDL-C mean and variability, respectively. Main Outcome Measures Newly developed diabetes. Results There were 122,192 cases (2.4%) of incident diabetes during the median follow-up of 5.1 years. Lower mean or higher variability of HDL-C was associated with higher risk of diabetes in a stepwise manner, and an additive effect of the two measures was noted. In the multivariable-adjusted model, the hazard ratios and 95% CIs for incident diabetes were 1.20 (1.18 to 1.22) in the high mean/high VIM group, 1.35 (1.33 to 1.37) in the low mean/low VIM group, and 1.40 (1.38 to 1.42) in the low mean/high VIM group compared with the high mean/low VIM group. Similar results were observed when modeling the variability using CV and in various subgroup analyses. Conclusions Low mean and high variability in HDL-C were independent predictors of diabetes with an additive effect. Both elevating and stabilizing HDL-C may be important goals for reducing diabetes risk.


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