Association between marginally low birth weight and obesity-related outcomes indirect effects via ADHD and abnormal eating

Background: Evidence of the association between children born with marginally low birth weight (MLBW) and obesity-related outcomes was controversial, and our study aimed to examine the role of attention deficit hyperactivity disorder (ADHD) and/or abnormal eating in these associations. Methods: A retrospective cohort study consisting of 677 Chinese children was conducted. Obesity-related outcomes (BMI, waist circumference, skin fold thickness, body fat, blood pressure, lipids and blood glucose), behaviour problems (ADHD and eating behaviour) and birth weight were collected. Mediation analyses were used to explore whether ADHD and/or abnormal eating was an intermediary factor in the MLBW-OB relationship. Results: The children with MLBW tended to have higher skin fold thickness, triglycerides, fasting blood glucose, waistline, body fat and abdominal obesity risks. Birth weight was negatively related to obesity-related outcomes, and the associations were mediated, partially, by increased risk of ADHD or abnormal eating behaviour after adjustment for BMI z-score. Furthermore, lower birth weight predicted higher waist circumference indirectly through emotional overeating caused by ADHD (β: -0.10; 95% CI: -0.19, -0.01). Conclusion: Our study suggests the hypothetical role of ADHD and abnormal eating as underlying mechanisms in the association between MBLW and obesity-related outcomes, which provides novel scientific evidence for interventions of childhood development.

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Body fat indices for identifying risk of hypertension in Indian children

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20193752 ◽

2019 ◽

Vol 6 (5) ◽

pp. 2116

Author(s):

Vairamuthu G. S. ◽

Thangavel A.

Keyword(s):

Blood Pressure ◽

Waist Circumference ◽

Body Fat ◽

Height Ratio ◽

Indian Children ◽

Skin Fold Thickness ◽

Skin Fold ◽

Triceps Skin Fold ◽

Waist To Height Ratio ◽

Triceps Skin Fold Thickness

Background: Studies in India shown high body fat indices were strongly associated with hypertension in Indian children, but such studies mostly not done in southern states of India. So, authors include children in Tamilnadu measure body fat indices and blood pressure to find which body fat index correlates closely with hypertension.Methods: Standing height was measured using stadiometer. Weight was measured using electronic scale. WC measured in standing position, by a stretch resistant. WC above 90th centile will be considered as Adipose. Waist to height ratio optimal cut-off value is 0.44 for children. TSFT recorded using Harpenden caliper, on the non-dominant upper arm. Wrist circumference measured using stretch resistant tape.Results: In this study 2000 children were participated. More hypertensives are seen in 10 to 12 years(62) and 16 to 18 years(31).Increased weight correlated with hypertension. Study indicates waist circumference is significantly correlated with systolic BP p<0.003, diastolic BP p<0.000. This study shows significant correlation p<0.003 for systolic and p<0.000 for diastolic BP with triceps skin fold thickness estimation. In multivariate analysis with systolic blood pressure and diastolic blood pressure shows very strong correlation with waist circumference, waist to height ratio and triceps skin fold thickness.Conclusions: In this study we investigate the correlation between body fat indices and blood pressure correlation was statistically analyzed which shows that waist circumference, waist to height ratio and triceps skin fold thickness were strongly correlated with systolic and diastolic BP.

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The role of very low birth weight and prematurity on cardiovascular disease risk and on kidney development in children: a pilot study

Minerva Pediatrica ◽

10.23736/s0026-4946.16.04520-5 ◽

2020 ◽

Vol 72 (3) ◽

Cited By ~ 1

Author(s):

Marco M. Ciccone ◽

Francesca Cortese ◽

Michele Gesualdo ◽

Antonio Di Mauro ◽

Silvio Tafuri ◽

...

Keyword(s):

Cardiovascular Disease ◽

Birth Weight ◽

Pilot Study ◽

Low Birth Weight ◽

Kidney Development ◽

Very Low Birth Weight ◽

Disease Risk ◽

Cardiovascular Disease Risk

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06 - THE ROLE OF C-REACTIVE PROTEIN IN THE DIAGNOSIS OF EARLY-ONSET SEPSIS IN VERY LOW BIRTH WEIGHT INFANTS

10.26226/morressier.5b5f2d47b56e9b003813db10 ◽

2018 ◽

Author(s):

Fleur Keij

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Early Onset ◽

Very Low Birth Weight ◽

C Reactive Protein ◽

Low Birth Weight Infants ◽

Reactive Protein ◽

Early Onset Sepsis

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249 ROLE OF DE NOVO LIPOGENESIS IN GROWING VERY LOW BIRTH WEIGHT BREASTFED INFANTS.

Journal of Investigative Medicine ◽

10.1136/jim-52-suppl1-249 ◽

2004 ◽

Vol 52 (Suppl 1) ◽

pp. S122.6-S123

Author(s):

M. Garg ◽

C. Bell ◽

L. Rogers ◽

S. Bassilian ◽

W. N.P. Lee

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Very Low Birth Weight ◽

De Novo ◽

De Novo Lipogenesis ◽

Breastfed Infants

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Impact of prenatal exercise on neonatal and childhood outcomes: a systematic review and meta-analysis

British Journal of Sports Medicine ◽

10.1136/bjsports-2018-099836 ◽

2018 ◽

Vol 52 (21) ◽

pp. 1386-1396 ◽

Cited By ~ 41

Author(s):

Margie H Davenport ◽

Victoria L Meah ◽

Stephanie-May Ruchat ◽

Gregory A Davies ◽

Rachel J Skow ◽

...

Keyword(s):

Systematic Review ◽

Body Weight ◽

Birth Weight ◽

Low Birth Weight ◽

Body Fat ◽

Gestational Age ◽

Fat Body ◽

Meta Analysis ◽

Prenatal Exercise ◽

Frequency Intensity

ObjectiveWe aimed to identify the relationship between maternal prenatal exercise and birth complications, and neonatal and childhood morphometric, metabolic and developmental outcomes.DesignSystematic review with random-effects meta-analysis and meta-regression.Data sourcesOnline databases were searched up to 6 January 2017.Study eligibility criteriaStudies of all designs were eligible (except case studies and reviews) if published in English, Spanish or French, and contained information on the relevant population (pregnant women without contraindication to exercise), intervention (subjective/objective measures of frequency, intensity, duration, volume or type of exercise, alone (‘exercise-only’) or in combination with other intervention components (eg, dietary; ‘exercise+cointervention’)), comparator (no exercise or different frequency, intensity, duration, volume, type or trimester of exercise) and outcomes (preterm birth, gestational age at delivery, birth weight, low birth weight (<2500 g), high birth weight (>4000 g), small for gestational age, large for gestational age, intrauterine growth restriction, neonatal hypoglycaemia, metabolic acidosis (cord blood pH, base excess), hyperbilirubinaemia, Apgar scores, neonatal intensive care unit admittance, shoulder dystocia, brachial plexus injury, neonatal body composition (per cent body fat, body weight, body mass index (BMI), ponderal index), childhood obesity (per cent body fat, body weight, BMI) and developmental milestones (including cognitive, psychosocial, motor skills)).ResultsA total of 135 studies (n=166 094) were included. There was ‘high’ quality evidence from exercise-only randomised controlled trials (RCTs) showing a 39% reduction in the odds of having a baby >4000 g (macrosomia: 15 RCTs, n=3670; OR 0.61, 95% CI 0.41 to 0.92) in women who exercised compared with women who did not exercise, without affecting the odds of growth-restricted, preterm or low birth weight babies. Prenatal exercise was not associated with the other neonatal or infant outcomes that were examined.ConclusionsPrenatal exercise is safe and beneficial for the fetus. Maternal exercise was associated with reduced odds of macrosomia (abnormally large babies) and was not associated with neonatal complications or adverse childhood outcomes.

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