The human parvovirus B19/human immunodeficiency virus co-infection in healthy eligible voluntary blood donors at the Blood Transfusion National Center in Kinshasa

Introduction. The first cases of human immunodeficiency virus infection and the first transmission of human immunodeficiency virus infection through blood transfusion in Vojvodina were registered in 1985. The aims of this study were to determine the ten-year trend of human immunodeficiency virus infection among blood donors in South Backa District of Vojvodina, routes of transmission and risk factors. Material and Methods. A retrospective study was conducted at the Blood Transfusion Institute of Vojvodina during 2009 - 2018, and human immunodeficijenca antigens and antibodies were analyzed. A total of 300 936 blood donor samples were screened using combined antibody-antigen tests (fourth generation enzyme-linked immunosorbent assay and chemiluminescence). Further testing included confirmatory immunoblot assay and molecular assay. Results. The overall human immunodeficiency virus seroprevalence was 3.7 per 100 000 donations. The number of blood donors found to be human immunodeficiency virus positive has increased during the study period showing a positive trend. The highest number of human immunodeficiency virus positive results was reported among blood donors aged 26-35 (36%) and 46-55 years (27%). The infection was more frequent in males. The leading rout of transmission was through unprotected sexual intercourse. Higher human immunodeficiency virus prevalence was among regular blood donors (73%). Conclusion. This study points to the importance of careful selection of blood donors and their education about risk behavior in order to reduce the risk of human immunodeficiency virus transmission. Concomitant use of sensitive serological and molecular tests is crucial to increase the blood safety.

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Seroprevalence of human immunodeficiency virus in Nepalese blood donors: A study from three regional blood transfusion services

Asian Journal of Transfusion Science ◽

10.4103/0973-6247.42663 ◽

2008 ◽

Vol 2 (2) ◽

pp. 66 ◽

Cited By ~ 5

Author(s):

BishnuRaj Tiwari ◽

Prakash Ghimire ◽

Surendra Karki ◽

Manita Rajkarnikar

Keyword(s):

Human Immunodeficiency Virus ◽

Blood Transfusion ◽

Blood Donors ◽

Immunodeficiency Virus

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Screening of viral markers for HIV HBV and HCV infections in blood donors in France and residual risk of viral transmission by blood transfusion

Eurosurveillance ◽

10.2807/esm.03.07.00115-en ◽

1998 ◽

Vol 3 (7) ◽

pp. 76-9 ◽

Cited By ~ 20

Author(s):

J Pillonel ◽

C Saura ◽

A M Couroucé

Keyword(s):

Human Immunodeficiency Virus ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Blood Transfusion ◽

Hepatitis B ◽

Blood Donors ◽

Hepatitis B Surface Antigen ◽

Viral Transmission ◽

Screening Tests ◽

Immunodeficiency Virus

The first part of this article presents the results of screening tests for antibodies to human immunodeficiency virus (HIV) and hepatitis C virus (HCV) and for hepatitis B surface antigen (HBsAg) from 1986 to 1996. The second part presents the most recent

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Trends and epidemiological analysis of hepatitis B virus, hepatitis C virus, human immunodeficiency virus, and human T-cell lymphotropic virus among Iranian blood donors: strategies for improving blood safety

BMC Infectious Diseases ◽

10.1186/s12879-020-05405-9 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Azadeh Omidkhoda ◽

Bahman Razi ◽

Ali Arabkhazaeli ◽

Sedigheh Amini Kafi-Abad

Keyword(s):

Human Immunodeficiency Virus ◽

Hepatitis C ◽

Blood Transfusion ◽

Blood Donors ◽

Blood Safety ◽

Blood Donations ◽

Human T Cell ◽

B Virus ◽

Immunodeficiency Virus ◽

First Time

Abstract Background Blood transfusion is associated with potential risks of transfusion-transmitted infections (TTIs). Different strategies are needed to monitor blood safety and screen the donors’ efficacy, such as evaluation of the prevalence and trends of TTIs. This study was conducted to evaluate the prevalence and trends of TTIs, including hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and human T-cell lymphotropic virus (HTLV 1/2), and the impact of the donors’ characteristics such as age, sex, and donor status on the prevalence of TTIs in blood donors in seven large provinces of Iran from 2010 to 2018. Methods This study was conducted on the data collected from all blood donations in seven Iranian Blood Transfusion Centers including Ardabil, Alborz, Guilan, West Azarbaijan, North, Razavi, and South Khorasan from April 2010 to March 2018. Demographic characteristics, number of donations, donor status, and screening and confirmatory serological results of all blood donations were collected from Iranian Blood Transfusion Organizations (IBTO) national database. The prevalence and trend of HBV, HCV, HIV, and HTLV 1/2 infections were reported according to the donation year and donor’s characteristics. Results The analysis of the prevalence and trend of TTIs in 3,622,860 blood donors showed a significant decreasing trend in first-time and regular donors. Additionally, compared to first- time donors, regular donors made safer blood donations with lower risks of HBV, HIV, HCV and HTLV 1/2 (P < 0.0001). Although the prevalence of HTLV 1/2 and HBV was higher in females, TTIs had a significant decreasing trend in males and females. Finally, it was found that the prevalence of HBV and HTLV 1/2 increased with age up to 40–49 years and then decreased thereafter. Conclusions The decreasing trends of TTIs in Iranian donors during 9 years may indicate that the various strategies implemented by IBTO have been effective in recent years. Other factors such as a decrease in the prevalence of specific TTIs in the general population might have also contributed to these declines.

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