Corneal Confocal Microscopy Detects Small-Fiber Neuropathy in Burning Mouth Syndrome: A Cross-Sectional Study

2019 ◽  
Vol 33 (3) ◽  
pp. 337-341 ◽  
Author(s):  
Francis O’Neill ◽  
Andrew Marshall ◽  
Maryam Ferdousi ◽  
Rayaz Malik
2018 ◽  
Vol 9 (6) ◽  
pp. 256 ◽  
Author(s):  
Maryam Rabiei ◽  
EhsanKazemnezhad Leili ◽  
Leili Alizadeh

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 722
Author(s):  
Pia López-Jornet ◽  
Yolanda Collado ◽  
Alfonso Zambudio ◽  
Eduardo Pons-Fuster ◽  
Candela Castillo Felipe ◽  
...  

Taste and smell are considered to be functions that contribute to the maintenance of good nutritional status. The present study evaluates taste and smell function in patients with burning mouth syndrome (BMS) versus a control group. A cross-sectional study was made of 36 consecutive patients with BMS and 56 healthy patients. Smell was assessed using the Sniffin’ Sticks test, while taste was evaluated with Taste Strips. Oral quality of life was assessed with the Oral Health Impact Profile-14 (OHIP-14), and the severity of dry mouth with the Thompson Xerostomia Inventory. The patients with BMS had a mean age of 60.4 ± 10.5 years, while the controls had a mean age of 61.3 ± 19 years. No significant differences in smell were recorded between the two groups. In contrast, significant differences in taste function were observed between the patients with BMS and the controls. In the patients with BMS, 44.4% suffered taste alterations compared with the 3.4% healthy controls. Further studies in such patients are needed to allow improved management of the chemosensory problems, mouth dryness, and oral health-related quality of life in BMS.


2018 ◽  
Vol 9 (5) ◽  
pp. 1167-1172 ◽  
Author(s):  
Adnan Khan ◽  
Ioannis N Petropoulos ◽  
Georgios Ponirakis ◽  
Robert A Menzies ◽  
Omar Chidiac ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Fahimeh Rezazadeh ◽  
Farzane Farahmand ◽  
Hamidreza Hosseinpour ◽  
Reza Shahriarirad ◽  
Amirhasan Sabet Eghlidi

Introduction. Burning mouth syndrome (BMS) is one of the challenging clinical problems not only in its diagnosis and treatment but also its concurring mental impact. This study is aimed at determining the association between psychological factors, including emotional stress, depression, anxiety, and sleep pattern among BMS patients. Methods. In this cross-sectional study, 19 patients with idiopathic BMS were enrolled along with a control group equivalent in age and sex, but without BMS. Questionnaires used were the Visual Analog Scale (VAS), the Pittsburgh Sleep Quality Index (PSQI), and the Depression, Anxiety, and Stress Scale (DASS-21). Demographic information was also recorded and analyzed. Results. There was a significant correlation among the two groups of BMS and non-BMS patients regarding stress, depression, and sleep disorder. The average severity of the burning score was 8.31 among the patients. Furthermore, a significant correlation was observed among mental disorders and educational level and sex, but not with age. There was also no significant correlation among the severity of the burning score with sex, education, and mental disorder. Conclusion. BMS is significantly associated with psychological symptoms. This condition requires proper treatment and support because it can represent psychological or mental issues and/or have a significant effect on daily life.


2021 ◽  
Vol 29 (1) ◽  
pp. 1-8
Author(s):  
Mariia V. Lukashenko ◽  
Natalia Y. Gavrilova ◽  
Anna V. Bregovskaya ◽  
Lidiia A. Soprun ◽  
Leonid P. Churilov ◽  
...  

Chronic pain may affect 30–50% of the world’s population and an important cause is small fiber neuropathy (SFN). Recent research suggests that autoimmune diseases may be one of the most common causes of small nerve fiber damage. There is low awareness of SFN among patients and clinicians and it is difficult to diagnose as routine electrophysiological methods only detect large fiber abnormalities, and specialized small fiber tests, like skin biopsy and quantitative sensory testing, are not routinely available. Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible method for quantifying small nerve fiber degeneration and regeneration, and could be an important tool for diagnosing SFN. This review considers the advantages and disadvantages of CCM and highlights the evolution of this technique from a research tool to a diagnostic test for small fiber damage, which can be a valuable contribution to the study and management of autoimmune disease.


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