Abstract 11839: Obesity Related Heart Rate Changes among Young Hispanic Women with Metabolic Syndrome

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Mini M Jose

Introduction: Visceral adiposity and metabolic syndrome have an earlier onset among Hispanic women due to genetic susceptibility. This study aimed to determine the association between changes in BMI, body weight and heart rate (HR) among Hispanic women aged 31-49years who met the ATP III criteria for metabolic syndrome and Obesity. Hypotheses: 1. There is a positive relationship between changes in BMI and Basal Heart rate 2. Patients with higher BMI will have a higher heart rate. Methods: In this retrospective study conducted in a community clinic, patient records meeting eligibility criteria were screened for three complete readings of anthropometric measurements and Vital signs. The readings taken when the patients had elevated temperature, respiratory rate, Blood pressure or when they were on Beta blockers were excluded. Final sample consisted of 61 records. Results: The sample BMI varied from 25 to 55 (Mean 34; SD 6) and the body weight ranged from 118lbs to 282lbs (Mean 188lbs; SD 35). The BMI change was between -4 to +4 (mean 1.15; SD 1.6), body weight change was from-30lbs to 22lbs (Mean 6.08 and SD 8.7) and the HR varied from -12 to 25 (mean 4.76; SD 8.38) Over 34 months. First hypothesis was accepted because Spearman Rho showed a significant positive correlation (r.298 p<.05) between changes in BMI and HR and between changes in body weight and HR (r.304 p<.05). A BMI change of one point raised the heart rate by 2beats/minute or 120beats/ hour accounting for 2,880 times/day. There was a no significant correlation between BMI and HR at all three data points leading reject the second hypothesis and conclude that the patients with highest BMI may not have the highest HR. Conclusions: The data showed that patients with metabolic syndrome and obesity suffer significant sympathetic stimulation raising basal HR, even when their blood pressure is controlled causing deleterious effect on already compromised heart with hypertension and atherosclerosis in metabolic syndrome. Patients with highest BMI may not have the highest HR due to failure to evoke an adequate sympathetic response and autonomic neuropathy signaling progressive chronic illnesses.

2018 ◽  
Vol 15 (2) ◽  
pp. 40-45
Author(s):  
Marina O. Galieva ◽  
Ekaterina A. Troshina ◽  
Nataliya V. Mazurina ◽  
Anna P. Volynkina ◽  
Andrey V. Artiushin ◽  
...  

Aims. To study of the polymorphisms of the TPN2 and GNB3 genes in obese patients and their effect on weight loss in patients on sibutramine therapy. Materials and methods. The research study included 118 patients with exogenous-constitutional obesity who received Reduxin (sibutramine + CMC) at the dose of 10 mg. Term follow-up was 3 months. A genetic study was performed to assess ТРН2 and GNB3 gene polymorphisms. The response to the therapy was evaluated after 3 months by the dynamics of body weight. Results. In the study the G703T polymorphism of the GNB3 gene showed that during 3 months of observation, carriers of the TT genotype had a greater decrease in body weight in comparison with carriers of the allele C -8 kg (-12; -5) vs. -5 kg (-8; -3), p = 0.018. In carriers of different variants of the genotype of the TPH2 gene (polymorphism C825T), there was no difference in body weight dynamics with sibutramine therapy. There was no correlation between the foresaid polymorphisms of the TPH2 and GNB3 genes with the indices of blood pressure and heart rate. Conclusions. 1. The result of sibutramin therapy may depend on genetic factors: in carriers of the TT-genotype C825T of the GNB3 gene the body weight loss was higher than among the carriers of the C allele. 2. Changes in blood pressure and heart rate did not show any statistically significant relationship with polymorphisms of the TPH2 and GNB3 genes.


2018 ◽  
Vol 15 (2) ◽  
pp. 40-45
Author(s):  
Marina O Galieva ◽  
Ekaterina A Troshina ◽  
Nataliya V Mazurina ◽  
Anna P Volynkina ◽  
Andrey Artiushin ◽  
...  

AIMS. To study of the polymorphisms of the TPN2 and GNB3 genes in obese patients and their effect on weight loss in patients on sibutramine therapy. MATERIALS AND METHODS. The research study included 118 patients with exogenous-constitutional obesity who received Reduxin (sibutramine + CMC) at the dose of 10 mg. Term follow-up was 3 months. A genetic study was performed to assess ТРН2 and GNB3 gene polymorphisms. The response to the therapy was evaluated after 3 months by the dynamics of body weight. RESULTS. In the study the G703T polymorphism of the GNB3 gene showed that during 3 months of observation, carriers of the TT genotype had a greater decrease in body weight in comparison with carriers of the allele C – -8 kg (-12; -5) vs. -5 kg (-8; -3), p = 0.018. In carriers of different variants of the genotype of the TPH2 gene (polymorphism C825T), there was no difference in body weight dynamics with sibutramine therapy. There was no correlation between the foresaid polymorphisms of the TPH2 and GNB3 genes with the indices of blood pressure and heart rate. CONCLUSIONS. 1. The result of sibutramin therapy may depend on genetic factors: in carriers of the TT-genotype C825T of the GNB3 gene the body weight loss was higher than among the carriers of the C allele. 2. Changes in blood pressure and heart rate did not show any statistically significant relationship with polymorphisms of the TPH2 and GNB3 genes.


2019 ◽  
Vol 15 (2) ◽  
pp. 173-177
Author(s):  
Zulkifli Ahmad ◽  
Mohd Najeb Jamaludin ◽  
Kamaruzaman Soeed

Vital sign monitoring is an important body measurement to identify health condition and diagnose any disease and illness. In sports, physical exercise will contribute to the changes of the physiological systems, specifically for the vital signs. Therefore, the objective of this study was to determine the effect of physical fatigue exercise on the vital sign parameters. This is significant for the fitness identification and prediction of each individual when performing an exercise. Five male subjects with no history of injuries and random BMI were selected from students of biomedical engineering, Universiti Teknologi Malaysia. Based on the relationship between physical movement and physiology, the parameters considered were heart rate, blood pressure, and body temperature. Subjects were required to run on the treadmill at an initial speed of 4 km/h with an increase of 1 km/h at every 2 minutes interval. The effect of exercise was marked according to the fatigue protocol where the subject was induced to the maximum condition of performance. All parameters were measured twice, for pre and post exercise-induced protocol. The analysis of relationship of each parameter between pre and post fatigue was p<0.05. The results revealed that the heart rate and gap between blood pressure’s systolic and diastolic were greater for all categories except underweight, where the systolic blood pressure dropped to below 100mmHg at the end of exercise. Also, the body temperature was slightly declined to balance the thermoregulatory system with sweating. Hence, the vigorous physical movement could contribute to the active physiological system based on body metabolism. Heart rate and blood pressure presented significant effects from the fatiguing exercise whereas the body temperature did not indicate any distinguishable impact. The results presented might act as the basis of reference for physical exercise by monitoring the vital sign parameters.


2020 ◽  
Author(s):  
Meixia Du ◽  
Jie Zhao ◽  
Xiaochun Yin ◽  
Nadi Zhang ◽  
Guisen Zheng

Background: Assessing the impact of vital signs (blood pressure, body temperature, heart rate, respiratory rate, and oxygen saturation) on the death of patients with new coronavirus pneumonia would provide a simple and convenient method for the monitoring of subsequent illness, and therefore, in some degree reduce treatment costs and increase the cure rate clinically. Methods: Six databases were retrieved. The software R 3.6.2 was used for meta-analysis of the included literature. Results: 12 studies were included, which comprise 8996 patients affected with COVID-19 infection. The meta-analysis study found that blood pressure (MAP, SBP and DBP), heart rate, respiration rate and SpO2 are the risk factors for disease progression in patients with COVID-19. Among them, the increase in MAP and the decrease in SpO2 have the greatest impact on the death of patients with COVID-19 [MAP: MD = 5.66, 95% CI (0.34, 10.98), SpO2: MD = -5.87, 95% CI (-9.17, -2.57), P = 0.0005]. However, comparing the body temperature of the death group and the survival group found that the body temperature was not statistically significant between the two groups [body temperature: MD = 0.21, 95% CI (-0.01, 0.43), P = 0.0661]. Conclusion: The increase in MAP, heart rate and respiratory rate, as well as the decrease in SBP, DBP and SpO2 are all independent risk factors for death in patients with COVID-19. These factors are simple and easy to monitor, and individualized treatment can be given to patients in time, reducing the mortality rate and improving treatment efficiency.


2019 ◽  
Vol 125 ◽  
pp. 25003
Author(s):  
Mery Subito ◽  
Alamsyah ◽  
Ardi Amir

Examination of vital signs such as blood pressure, heart rate, and body temperature is the most basic essential function of the body in determining the health status of the patient. In general, examining vital signs performed by a doctor or nurse uses an electrocardiogram, thermometer, and sphygmomanometer. However, this tool has a weakness in terms of time efficiency and accuracy of reading vital sign data. The process of taking vital sign data for a long time, the limited number of medical personnel in handling patients, and increasing administrative costs certainly become a concern for management in improving health services. To overcome this problem, we proposed a design that can monitor the health condition of patients' vital signs efficiently and in real time. The system used in this study consisted of an HRM-2511E type heartbeat sensor in pulse units per minute (bpm), DS18b20 body type temperature sensor in degrees Celsius (0C), and MPX5700AP sensor in mmHg units. This research is fundamental and is useful in helping medical personnel in monitoring patients' vital sign health conditions. The results of the proposed design showed that the heart rate, temperature, and blood pressure devices worked well with respective accuracy of 97.64%, 99.51%, and 97.53%.


2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Joanna Witkoś ◽  
Magdalena Hartman-Petrycka

Introduction: Medical science is constantly looking for effective methods to prevent involutional changes. Whole-body vibration training is a promising form of systemic rehabilitation. Aim: The aim of the study was to assess the effect of whole-body vibration on basic cardiovascular parameters (heart rate and blood pressure) and changes in the perception of an external stimulus in postmenopausal women with different body composition. Material and methods: The study was pilot and involved 20 women. Before the procedure, the body composition analysis was performed using the Tanita analyser. All participants underwent a series of vibration massage treatments lasting 30 minutes. Blood pressure, heart rate and sensory threshold levels were measured before and after the vibrotherapy. Results: Diastolic blood pressure before vs. after (median; 74.20 vs. 71.45 mmHg; p=0.047), heart rate before vs. after (median; 67.40 vs. 66.00 bpm; p<0.001). Higher water content positively correlated with a decrease in diastolic blood pressure (R=0.51; p<0.05). The older the woman was, the less the heart rate decreased (R=-0.45; p<0.05). After vibrotherapy, the sensory threshold values in the non-dominant hand decreased slightly (p=0.076). The greater the visceral fat content (R=-0.48; p<0.05) and body weight (R=-0.56; p<0.05), the smaller was the improvement in the threshold. Conclusions: After whole-body vibration, the values of diastolic blood pressure and heart rate in the examined women were lower than those recorded before the procedure. It has been shown that the higher water content in the female body was associated with a greater reduction in diastolic blood pressure. However, the older the woman, the less was the decrease in heart rate. After the whole-body vibrotherapy, only a slight decrease in the sensory threshold was noted. However, it was found that in the studied women the greater the content of visceral fat tissue and the body weight, the smaller the change in sensory sensitivity.


Author(s):  
Lola Mukhammedovna Saidbaeva ◽  
Rano Amanullaevna Alieva ◽  
Feruza Nasretdinovna Mirzabekova ◽  
Sohiba Mamasidikovna Sirojiddinova ◽  
Ismoiljon Adakhamzhonovich Mirzabekov ◽  
...  

Exercise makes high demands on the body, especially the female, due to its physiological characteristics. The article contains a study of the impact of athletics on the female body. Athletes 16-19 years old were studied somatometric (height, body weight, chest circumference, dynamometry of the hands) and psychometric (vital lung capacity, heart rate, blood pressure) indicators


GYNECOLOGY ◽  
2018 ◽  
Vol 20 (2) ◽  
pp. 9-13
Author(s):  
A R Khachaturian ◽  
E V Misharina ◽  
M I Yarmolinskaya

Androgen-dependent dermopathy, as well as premenstrual syndrome of varying severity in young women, can cause emotional depression, difficulties in social adaptation and even depressive disorders. The aim of the study was to study the safety and efficacy of using a combined oral contraceptive (COC) Dimia® containing 20 μg ethinyl estradiol and 3 mg drospirenone in young women, as well as its therapeutic effects in androgen-dependent dermopathy. Materials and methods. The study included 57 young women aged 23.1±2.2 years with signs of androgen-dependent dermopathy. The evaluation of the change in the character of menstrual bleeding, the anthropometric parameters (body weight, waist circumference and hips), the therapeutic effect of the drug on the symptoms of androgen-dependent dermopathy, as well as the dynamics of arterial pressure, hemoglobin level, serum iron have been studied. The psycho-emotional state was assessed using the SAN questionnaire (well-being-activity-mood). Results. During 6 months of observation, there was no significant change in the body mass index, waist circumference, and hips, and the drug did not affect the blood pressure numbers. Against the background of taking the drug, there was an increase in the parameters of iron metabolism (hemoglobin content, serum iron). After 3 months of taking the contraceptive with drospirenone, the number of patients with a complaint about the abundance of menstruation decreased more than twofold (from 22.8 to 10.5%), and after 6 months of taking the drug no patient noted the profuse nature of menstruation. Before the start of taking COC with drospirenone, 57.9% of women reported painful menstrual bleeding. Against the background of taking the contraceptive within 3 months, this complaint was stopped in all patients. Sufficient efficacy of treatment of androgen dependent dermopathy in young women with the help of a microdosed drospirenone-containing combined oral contraceptive is estimated from the dermatological acne index. The analysis of the SAN questionnaire made it possible to reveal the improvement in the psychoemotional state of patients on the background of taking the drug. The conclusion. The results obtained proved the effectiveness and safety of the microclinized COC Dimia®. The drug has no significant effect on body weight, blood pressure, provides reliable control of the cycle and a decrease in menstrual bleeding, which results in stabilization of iron metabolism in the body. Dimia® is effective in the treatment of androgen-dependent dermopathy and can be recommended to young women for starting contraception.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 914.2-914
Author(s):  
S. Boussaid ◽  
M. Ben Majdouba ◽  
S. Jriri ◽  
M. Abbes ◽  
S. Jammali ◽  
...  

Background:Music therapy is based on ancient cross-cultural beliefs that music can have a “healing” effect on mind and body. Research determined that listening to music can increase comfort and relaxation, relieve pain, lower distress, reduce anxiety, improve positive emotions and mood, and decrease psychological symptoms. Music therapy has been used greatly in various medical procedures to reduce associated anxiety and pain. Patients have a high level of anxiety when they are in the hospital, this is the case of patients with rheumatic diseases who consult regularly to have intravenous infusion of biological therapies.Objectives:The purpose of this study was to examine the effectiveness of music therapy on pain, anxiety, and vital signs among patients with chronic inflammatory rheumatic diseases during intravenous infusion of biological drugs.Methods:Fifty patients were divided into two groups: The experimental group G1 (n=25) received drug infusion while lestening to soft music (30 minutes); and the control group G2 (n=25) received only drug infusion. Measures include pain, anxiety, vital signs (blood pressure, heart rate and respiratory rate). The pain was measured using visual analogic scale (VAS). The state-trait anxiety inventory (STAI) was used for measuring anxiety, low anxiety ranges from 20 to 39, the moderate anxiety ranges from 40 to 59, and high anxiety ranges from 60 to 80. Vital signs (systolic blood pressure [SBP], diastolic blood pressure [DBP], heart rate [HR], and respiratory rate [RR]) were measured before, during and immediately after the infusion.Statistical package for social sciences (SPSS) was used for analysis.Results:The mean age in G1 was 44.45 years (26-72) with a sex ratio (M/F) of 0.8. Including the 25 patients, 12 had rheumatoid arthritis, 10 had ankylosing spondylitis and 3 had psoriatic arthritis. The mean disease duration was 8 years. In G2, the mean age was 46 years (25-70) with a sex ratio (M/F) of 0.75, 12 had rheumatoid arthritis, 11 had ankylosing spondylitis and 2 had psoriatic arthritis. The mean disease duration was 7.5 years. The biological drugs used were: Infliximab in 30 cases, Tocilizumab in 12 cases and Rituximab in 8 cases.Before the infusion, the patients of experimental group had a mean VAS of 5/10±3, a mean STAI of 50.62±6.01, a mean SBP of 13.6 cmHg±1.4, a mean DBP of 8.6 cmHg±1, a mean HR of 85±10 and a mean RR of 18±3. While in control group the mean VAS was 5.5±2, the mean STAI was 50.89±5.5, the mean SBP was 13.4±1.2, the mean DBP was 8.8±1.1, the mean HR was 82±8 and the mean RR was 19±2.During the infusion and after music intervention in G1, the mean STAI became 38.35±5 in G1 versus 46.7±5.2 in G2 (p value=0.022), the mean SBP became 12.1±0.5 in G1 versus 13±1 in G2 (p=0.035), the mean DBP became 8.1±0.8 in G1 versus 8.4±0.9 in G2 (p=0.4), the mean HR became 76±9 in G1 versus 78±7 in G2 (p=0.04) and the mean RR became 17.3±2.1 in G1 versus 18.2±1.7 in G2 (p=0.39).This study found a statistically significant decrease in anxiety, systolic blood pressure and heart rate in patients receiving music interventions during biological therapies infusion, but no significant difference were identified in diastolic blood pressure and respiratory rate.Conclusion:The findings provide further evidence to support the use of music therapy to reduce anxiety, and lower systolic blood pressure and heart rate in patients with rheumatic disease during biological therapies infusion.References:[1] Lin, C., Hwang, S., Jiang, P., & Hsiung, N. (2019).Effect of Music Therapy on Pain After Orthopedic Surgery -A Systematic review and Meta-Analysis. Pain Practice.Disclosure of Interests:None declared


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