Abstract WP269: Automatic Segmentation of Cerebral Arteries in MRA TOF Using Deep Learning

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Leonard L Yeo ◽  
Melih Engin ◽  
Robin Lange ◽  
Sethu R Boopathy ◽  
Yang Cunli ◽  
...  

Purpose: Time-of-Flight (TOF) MRA is commonly used for grading cerebrovascular diseases. Analysis of cerebral arteries in MRA TOF is a challenging and time consuming task that would benefit from automation. Established image processing methods for automatic segmentation of cerebral arteries suffer from common artefacts such as kissing vessels (when two nearby vessels touch) and signal intensity drop (especially in the presence of pathology). Artificial intelligence models are promising candidates for resolving such artefacts. Here, we propose and assess the performance of a deep learning model for automatic segmentation of cerebral arteries in MRA TOF which is robust to common MRI artefacts. Methods: A 3D convolutional neural network (CNN) is proposed for automatic segmentation of intracranial arteries in MRA TOF. The neural network is trained with a custom loss function and residual blocks to penalize the occurrence of common artefacts such as kissing vessels. The model is trained and tested on a dataset consisting of 82 subjects (50 healthy volunteers and 32 patients with intracranial stenosis) following a 3-fold cross-validation method, i.e. 3 models are trained where each model is blind to one-third of the data in the training process to avoid bias. Manual segmentation of the arteries done by an expert reader are used as ground-truth for training and testing the model. Results: The proposed deep learning model achieved excellent accuracy compared against the ground truth (Dice score 0.89). Our proposed deep learning model outperformed a state-of-the-art neural network for image segmentation (3DU-Net, Dice score 0.85) and resulted in considerably less occurences of artefacts such as kissing vessels (9% of cases had segmentation artefacts for our model vs 16% for 3D U-Net). The proposed deep learning model was fast, taking only 2 seconds to produce a 3D model of the arteries on a laptop with a dedicated GPU. Conclusion: The proposed deep learning model accurately segments intracranial arteries in MRA TOF and is robust to common artefacts of MR imaging thanks to implementation of a custom loss function. The model can potentially increase the accuracy and speed of grading cerebrovascular diseases.

2020 ◽  
Vol 13 (4) ◽  
pp. 627-640 ◽  
Author(s):  
Avinash Chandra Pandey ◽  
Dharmveer Singh Rajpoot

Background: Sentiment analysis is a contextual mining of text which determines viewpoint of users with respect to some sentimental topics commonly present at social networking websites. Twitter is one of the social sites where people express their opinion about any topic in the form of tweets. These tweets can be examined using various sentiment classification methods to find the opinion of users. Traditional sentiment analysis methods use manually extracted features for opinion classification. The manual feature extraction process is a complicated task since it requires predefined sentiment lexicons. On the other hand, deep learning methods automatically extract relevant features from data hence; they provide better performance and richer representation competency than the traditional methods. Objective: The main aim of this paper is to enhance the sentiment classification accuracy and to reduce the computational cost. Method: To achieve the objective, a hybrid deep learning model, based on convolution neural network and bi-directional long-short term memory neural network has been introduced. Results: The proposed sentiment classification method achieves the highest accuracy for the most of the datasets. Further, from the statistical analysis efficacy of the proposed method has been validated. Conclusion: Sentiment classification accuracy can be improved by creating veracious hybrid models. Moreover, performance can also be enhanced by tuning the hyper parameters of deep leaning models.


2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii359-iii359
Author(s):  
Lydia Tam ◽  
Edward Lee ◽  
Michelle Han ◽  
Jason Wright ◽  
Leo Chen ◽  
...  

Abstract BACKGROUND Brain tumors are the most common solid malignancies in childhood, many of which develop in the posterior fossa (PF). Manual tumor measurements are frequently required to optimize registration into surgical navigation systems or for surveillance of nonresectable tumors after therapy. With recent advances in artificial intelligence (AI), automated MRI-based tumor segmentation is now feasible without requiring manual measurements. Our goal was to create a deep learning model for automated PF tumor segmentation that can register into navigation systems and provide volume output. METHODS 720 pre-surgical MRI scans from five pediatric centers were divided into training, validation, and testing datasets. The study cohort comprised of four PF tumor types: medulloblastoma, diffuse midline glioma, ependymoma, and brainstem or cerebellar pilocytic astrocytoma. Manual segmentation of the tumors by an attending neuroradiologist served as “ground truth” labels for model training and evaluation. We used 2D Unet, an encoder-decoder convolutional neural network architecture, with a pre-trained ResNet50 encoder. We assessed ventricle segmentation accuracy on a held-out test set using Dice similarity coefficient (0–1) and compared ventricular volume calculation between manual and model-derived segmentations using linear regression. RESULTS Compared to the ground truth expert human segmentation, overall Dice score for model performance accuracy was 0.83 for automatic delineation of the 4 tumor types. CONCLUSIONS In this multi-institutional study, we present a deep learning algorithm that automatically delineates PF tumors and outputs volumetric information. Our results demonstrate applied AI that is clinically applicable, potentially augmenting radiologists, neuro-oncologists, and neurosurgeons for tumor evaluation, surveillance, and surgical planning.


Symmetry ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2293
Author(s):  
Zixiang Yue ◽  
Youliang Ding ◽  
Hanwei Zhao ◽  
Zhiwen Wang

A cable-stayed bridge is a typical symmetrical structure, and symmetry affects the deformation characteristics of such bridges. The main girder of a cable-stayed bridge will produce obvious deflection under the inducement of temperature. The regression model of temperature-induced deflection is hoped to provide a comparison value for bridge evaluation. Based on the temperature and deflection data obtained by the health monitoring system of a bridge, establishing the correlation model between temperature and temperature-induced deflection is meaningful. It is difficult to complete a high-quality model only by the girder temperature. The temperature features based on prior knowledge from the mechanical mechanism are used as the input information in this paper. At the same time, to strengthen the nonlinear ability of the model, this paper selects an independent recurrent neural network (IndRNN) for modeling. The deep learning neural network is compared with machine learning neural networks to prove the advancement of deep learning. When only the average temperature of the main girder is input, the calculation accuracy is not high regardless of whether the deep learning network or the machine learning network is used. When the temperature information extracted by the prior knowledge is input, the average error of IndRNN model is only 2.53%, less than those of BPNN model and traditional RNN. Combining knowledge with deep learning is undoubtedly the best modeling scheme. The deep learning model can provide a comparison value of bridge deformation for bridge management.


2021 ◽  
Vol 14 (6) ◽  
pp. 3421-3435
Author(s):  
Zhenjiao Jiang ◽  
Dirk Mallants ◽  
Lei Gao ◽  
Tim Munday ◽  
Gregoire Mariethoz ◽  
...  

Abstract. This study introduces an efficient deep-learning model based on convolutional neural networks with joint autoencoder and adversarial structures for 3D subsurface mapping from 2D surface observations. The method was applied to delineate paleovalleys in an Australian desert landscape. The neural network was trained on a 6400 km2 domain by using a land surface topography as 2D input and an airborne electromagnetic (AEM)-derived probability map of paleovalley presence as 3D output. The trained neural network has a squared error <0.10 across 99 % of the training domain and produces a squared error <0.10 across 93 % of the validation domain, demonstrating that it is reliable in reconstructing 3D paleovalley patterns beyond the training area. Due to its generic structure, the neural network structure designed in this study and the training algorithm have broad application potential to construct 3D geological features (e.g., ore bodies, aquifer) from 2D land surface observations.


Water ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 2664
Author(s):  
Sunil Saha ◽  
Jagabandhu Roy ◽  
Tusar Kanti Hembram ◽  
Biswajeet Pradhan ◽  
Abhirup Dikshit ◽  
...  

The efficiency of deep learning and tree-based machine learning approaches has gained immense popularity in various fields. One deep learning model viz. convolution neural network (CNN), artificial neural network (ANN) and four tree-based machine learning models, namely, alternative decision tree (ADTree), classification and regression tree (CART), functional tree and logistic model tree (LMT), were used for landslide susceptibility mapping in the East Sikkim Himalaya region of India, and the results were compared. Landslide areas were delimited and mapped as landslide inventory (LIM) after gathering information from historical records and periodic field investigations. In LIM, 91 landslides were plotted and classified into training (64 landslides) and testing (27 landslides) subsets randomly to train and validate the models. A total of 21 landslide conditioning factors (LCFs) were considered as model inputs, and the results of each model were categorised under five susceptibility classes. The receiver operating characteristics curve and 21 statistical measures were used to evaluate and prioritise the models. The CNN deep learning model achieved the priority rank 1 with area under the curve of 0.918 and 0.933 by using the training and testing data, quantifying 23.02% and 14.40% area as very high and highly susceptible followed by ANN, ADtree, CART, FTree and LMT models. This research might be useful in landslide studies, especially in locations with comparable geophysical and climatological characteristics, to aid in decision making for land use planning.


Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Yannan Yu ◽  
Soren Christensen ◽  
Yuan Xie ◽  
Enhao Gong ◽  
Maarten G Lansberg ◽  
...  

Objective: Ischemic core prediction from CT perfusion (CTP) remains inaccurate compared with gold standard diffusion-weighted imaging (DWI). We evaluated if a deep learning model to predict the DWI lesion from MR perfusion (MRP) could facilitate ischemic core prediction on CTP. Method: Using the multi-center CRISP cohort of acute ischemic stroke patient with CTP before thrombectomy, we included patients with major reperfusion (TICI score≥2b), adequate image quality, and follow-up MRI at 3-7 days. Perfusion parameters including Tmax, mean transient time, cerebral blood flow (CBF), and cerebral blood volume were reconstructed by RAPID software. Core lab experts outlined the stroke lesion on the follow-up MRI. A previously trained MRI model in a separate group of patients was used as a starting point, which used MRP parameters as input and RAPID ischemic core on DWI as ground truth. We fine-tuned this model, using CTP parameters as input, and follow-up MRI as ground truth. Another model was also trained from scratch with only CTP data. 5-fold cross validation was used. Performance of the models was compared with ischemic core (rCBF≤30%) from RAPID software to identify the presence of a large infarct (volume>70 or >100ml). Results: 94 patients in the CRISP trial met the inclusion criteria (mean age 67±15 years, 52% male, median baseline NIHSS 18, median 90-day mRS 2). Without fine-tuning, the MRI model had an agreement of 73% in infarct >70ml, and 69% in >100ml; the MRI model fine-tuned on CT improved the agreement to 77% and 73%; The CT model trained from scratch had agreements of 73% and 71%; All of the deep learning models outperformed the rCBF segmentation from RAPID, which had agreements of 51% and 64%. See Table and figure. Conclusions: It is feasible to apply MRP-based deep learning model to CT. Fine-tuning with CTP data further improves the predictions. All deep learning models predict the stroke lesion after major recanalization better than thresholding approaches based on rCBF.


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