Establishment of Cut Off Values for Various Impulse Oscillometry (IOS) Parameters for Detection of Exercise Induced Bronchoconstriction (EIB) in Children with Asthma Aged 6 to 15 Years

We investigated whether a 1-week stay in the mountains may have a positive impact on Exercise-Induced Bronchoconstriction (EIB) and cardiorespiratory endurance in asthmatic children from an urban area. Spirometry was performed before and 10 min after a 20 m shuttle run test (20mSRT) on the first and seventh day of a summer asthma camp in the Italian Alps at 900 m of altitude. Spirometry z-scores were derived from the Global Lung Initiative 2012 prediction equations, and percentiles of the 20mSRT performance were assigned according to De Miguel-Etayo’s and Tomkinson’s predictive equations. A FEV1 decrease ≥10% after the exercise was defined as EIB. Particulate matter pollution was monitored during the camp and in the urban area of provenience. Twenty-four subjects (age range 7–16 years) were included. Frequency of EIB decreased from 58% (14/24) at day-1 to 33% (8/24) at the end of the camp (p = 0.08). Most subjects with a 20mSRT in the lowest quartile at day 1 had EIB (9/11). The proportion of children with a 20mSRT <25° percentile decreased from 45% (11/24) at day-1 to 16% (4/24) at day-7 (p = 0.02). Conclusion: One-week climate therapy in the mountains improved both bronchial hyperreactivity and cardiorespiratory endurance in our cohort of asthmatic children.

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Effect of different antiasthmatic treatments on exercise-induced bronchoconstriction in children with asthma

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2007.09.007 ◽

2008 ◽

Vol 121 (2) ◽

pp. 383-389 ◽

Cited By ~ 69

Author(s):

Iwona Stelmach ◽

Tomasz Grzelewski ◽

Pawel Majak ◽

Joanna Jerzynska ◽

Wlodzimierz Stelmach ◽

...

Keyword(s):

Children With Asthma ◽

Exercise Induced

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Exercise-Induced Airway Characteristics of Young Asthmatics Measured by Impulse Oscillometry.

10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5083 ◽

2009 ◽

Author(s):

J Lee ◽

Y Lee ◽

Y Shin ◽

C Hong ◽

J Park

Keyword(s):

Impulse Oscillometry ◽

Exercise Induced

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Comparing Bronchodilator Response Measured by Impulse Oscillometry to Spirometry in Children with Asthma.

10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4858 ◽

2009 ◽

Author(s):

KD Graw-Panzer ◽

R Socher ◽

A Bhardwaj ◽

I Mina ◽

H Lee ◽

...

Keyword(s):

Impulse Oscillometry ◽

Bronchodilator Response ◽

Children With Asthma

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Exercise, physical activity, and asthma

10.1093/med/9780198757672.003.0024 ◽

2017 ◽

Author(s):

Helge Hebestreit ◽

Susi Kriemler ◽

Thomas Radtke

Keyword(s):

Physical Activity ◽

Challenge Test ◽

Well Being ◽

Physical Activities ◽

Shortness Of Breath ◽

Chest Tightness ◽

Exercise Challenge ◽

Typical History ◽

Children With Asthma ◽

Exercise Induced

The incidence of asthma in children varies among countries and can be estimated to range between 5% and 20%. Exercise-induced asthma (EIA) is common in patients with asthma but can also occur in some children without asthma. Typical symptoms of EIA include cough, chest tightness, and shortness of breath shortly after exercise. The pathophysiology of EIA is not completely understood, but it has been shown that airway cooling and drying with increased ventilation during exercise and airway re-warming after exercise play a pivotal role. In addition, a lack of physical activity may also contribute to EIA. Regular exercise may increase fitness and psychological well-being but may also positively influence airway inflammation in children with asthma. The diagnosis of EIA is based on the typical history and may be verified by an exercise challenge test. Every child with EIA should be able to engage in all type of physical activities.

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