Eosinophils play a major role in the severity of exercise-induced bronchoconstriction in children with asthma

2006 ◽  
Vol 41 (12) ◽  
pp. 1161-1166 ◽  
Author(s):  
So-Yeon Lee ◽  
Hyo-Bin Kim ◽  
Ja-Hyung Kim ◽  
Bong-Seong Kim ◽  
Mi-Jin Kang ◽  
...  
2010 ◽  
Vol 37 (6) ◽  
pp. 1366-1370 ◽  
Author(s):  
I. Chinellato ◽  
M. Piazza ◽  
M. Sandri ◽  
D. G. Peroni ◽  
F. Cardinale ◽  
...  

Atmosphere ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1486
Author(s):  
Carlo De Pieri ◽  
Michele Arigliani ◽  
Maria Pia Francescato ◽  
Maurizio Droli ◽  
Michael Vidoni ◽  
...  

We investigated whether a 1-week stay in the mountains may have a positive impact on Exercise-Induced Bronchoconstriction (EIB) and cardiorespiratory endurance in asthmatic children from an urban area. Spirometry was performed before and 10 min after a 20 m shuttle run test (20mSRT) on the first and seventh day of a summer asthma camp in the Italian Alps at 900 m of altitude. Spirometry z-scores were derived from the Global Lung Initiative 2012 prediction equations, and percentiles of the 20mSRT performance were assigned according to De Miguel-Etayo’s and Tomkinson’s predictive equations. A FEV1 decrease ≥10% after the exercise was defined as EIB. Particulate matter pollution was monitored during the camp and in the urban area of provenience. Twenty-four subjects (age range 7–16 years) were included. Frequency of EIB decreased from 58% (14/24) at day-1 to 33% (8/24) at the end of the camp (p = 0.08). Most subjects with a 20mSRT in the lowest quartile at day 1 had EIB (9/11). The proportion of children with a 20mSRT <25° percentile decreased from 45% (11/24) at day-1 to 16% (4/24) at day-7 (p = 0.02). Conclusion: One-week climate therapy in the mountains improved both bronchial hyperreactivity and cardiorespiratory endurance in our cohort of asthmatic children.


2008 ◽  
Vol 121 (2) ◽  
pp. 383-389 ◽  
Author(s):  
Iwona Stelmach ◽  
Tomasz Grzelewski ◽  
Pawel Majak ◽  
Joanna Jerzynska ◽  
Wlodzimierz Stelmach ◽  
...  

Author(s):  
Helge Hebestreit ◽  
Susi Kriemler ◽  
Thomas Radtke

The incidence of asthma in children varies among countries and can be estimated to range between 5% and 20%. Exercise-induced asthma (EIA) is common in patients with asthma but can also occur in some children without asthma. Typical symptoms of EIA include cough, chest tightness, and shortness of breath shortly after exercise. The pathophysiology of EIA is not completely understood, but it has been shown that airway cooling and drying with increased ventilation during exercise and airway re-warming after exercise play a pivotal role. In addition, a lack of physical activity may also contribute to EIA. Regular exercise may increase fitness and psychological well-being but may also positively influence airway inflammation in children with asthma. The diagnosis of EIA is based on the typical history and may be verified by an exercise challenge test. Every child with EIA should be able to engage in all type of physical activities.


2011 ◽  
Vol 32 (6) ◽  
pp. 425-430 ◽  
Author(s):  
Nancy K. Ostrom ◽  
Nemr S. Eid ◽  
Timothy J. Craig ◽  
Gene L. Colice ◽  
Mary Lou Hayden ◽  
...  

1998 ◽  
Vol 133 (3) ◽  
pp. 424-428 ◽  
Author(s):  
James P. Kemp ◽  
Robert J. Dockhorn ◽  
Gail G. Shapiro ◽  
Ha H. Nguyen ◽  
Theodore F. Reiss ◽  
...  

2022 ◽  
Vol 8 (4) ◽  
pp. 365-288
Author(s):  
Mohammed Shamssain ◽  
Anisa Alhamadi ◽  
Siba Nezar Al Afandi ◽  
Tasneem Naeem Awadallah ◽  
Shatha Naeem Awadallah

Very few studies have been carried out on asthma and allergies in pre-schoolchildren. This is the first study of pre-school children with asthma and allergies in the United Arab Emirates. We studied 4,000 pre-schoolchildren from the United Arab Emirates: Dubai, Sharjah, Abu Dhabi, and Al-Ain. The ages of the study group were between 1-5 years, and were 2,000 boys and 2,000 girls; they were randomly selected from kindergartens and nurseries. We used the standardised International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. The mean (SD) age, height, weight and BMI were 3.3 (1.4) years, 92.0 (1.3) cm, 17.3 (5.2) kg, and 23.4 (9.3). The prevalence rates of “wheeze ever”, “current wheeze”, “speech limitation”, “asthma” , “dry night cough”, and “exercise-induced asthma” were 40.4%, 43.8%, 37.6%, 26.5%, 36.1, and 37.6%, respectively. Boys had a significantly higher prevalence of wheeze ever and current wheeze than girls. Girls had a significantly higher prevalence of speech limitation than boys. The prevalence rates of “rhinitis ever”, “current rhinitis”, “itchy watery eyes” and “hay fever” were 42%, 40.5%, 39.1% and 46.9%, respectively. Boys had significantly higher prevalence rates of “rhinitis ever”, “current rhinitis”, and “itchy watery eyes” than girls. The prevalence rates of “rash ever”, “current rash” and “eczema ever” were 38.9%, 33.7% and 58.0%, respectively. Boys had significantly higher prevalence rates of rash ever, current rash, and eczema ever than girls. Children who were exposed to parental smoking have significantly higher prevalence rates of asthma, wheezing, and cough than those whom were not exposed. Children who breastfed more than 10 months had a significantly lower prevalence rates of “wheeze ever”, “current wheeze”, “speech limitation”, and “asthma”, than those whom breastfed less than 10 months. The prevalence rates of asthma, rhinitis and eczema were very high. Breastfeeding was found to be protective for asthma. The study can be used as a baseline intervention project to reduce incidents of asthma and allergies in these children and to establish atopic march in order to implement strategies to improve the respiratory health and allergies in these children. Keywords: asthma, wheeze, night cough, rhinitis, eczema, pre-school children, paediatric asthma


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