High Glucose Enhances Responsiveness of Human Airways Smooth Muscle via the Rho/ROCK Pathway

Mario Cazzola; Luigino Calzetta; Paola Rogliani; Davide Lauro; Lucia Novelli; Clive P. Page; Varsha Kanabar; Maria Gabriella Matera

doi:10.1165/rcmb.2011-0449oc

High Glucose Enhances Responsiveness of Human Airways Smooth Muscle via the Rho/ROCK Pathway

American Journal of Respiratory Cell and Molecular Biology ◽

10.1165/rcmb.2011-0449oc ◽

2012 ◽

Vol 47 (4) ◽

pp. 509-516 ◽

Cited By ~ 42

Author(s):

Mario Cazzola ◽

Luigino Calzetta ◽

Paola Rogliani ◽

Davide Lauro ◽

Lucia Novelli ◽

...

Keyword(s):

Smooth Muscle ◽

High Glucose ◽

Airways Smooth Muscle ◽

Human Airways

Identification in human airways smooth muscle cells of the prostanoid receptor and signalling pathway through which PGE2 inhibits the release of GM-CSF

British Journal of Pharmacology ◽

10.1038/sj.bjp.0705716 ◽

2004 ◽

Vol 141 (7) ◽

pp. 1141-1150 ◽

Cited By ~ 38

Author(s):

Deborah L Clarke ◽

Maria G Belvisi ◽

Matthew C Catley ◽

Magdi H Yacoub ◽

Robert Newton ◽

...

Keyword(s):

Smooth Muscle ◽

Smooth Muscle Cells ◽

Muscle Cells ◽

Signalling Pathway ◽

Prostanoid Receptor ◽

Gm Csf ◽

Airways Smooth Muscle ◽

Human Airways

Interleukin (il)-13-Mediated Inhibition Of Human Airways Smooth Muscle Cell Proliferation In Response To Serum Is Associated With Down-Regulation Of Kruppel-Like Factor 5

10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3629 ◽

2011 ◽

Author(s):

Paul-André Risse ◽

Taisuke Jo ◽

Pasquale Ferraro ◽

James Martin

Keyword(s):

Cell Proliferation ◽

Smooth Muscle ◽

Smooth Muscle Cell ◽

Muscle Cell ◽

Smooth Muscle Cell Proliferation ◽

Down Regulation ◽

Airways Smooth Muscle ◽

Human Airways

42 Nonadrenergic inhibition of human airways smooth muscle

Journal of Allergy and Clinical Immunology ◽

10.1016/0091-6749(83)90166-5 ◽

1983 ◽

Vol 71 (1) ◽

pp. 99

Author(s):

S TAYLOR ◽

R SOHELLENBERG

Keyword(s):

Smooth Muscle ◽

Airways Smooth Muscle ◽

Human Airways

Validation of the Anti-Inflammatory Properties of Small-Molecule IκB Kinase (IKK)-2 Inhibitors by Comparison with Adenoviral-Mediated Delivery of Dominant-Negative IKK1 and IKK2 in Human Airways Smooth Muscle

Molecular Pharmacology ◽

10.1124/mol.106.023150 ◽

2006 ◽

Vol 70 (2) ◽

pp. 697-705 ◽

Cited By ~ 54

Author(s):

Matthew C. Catley ◽

Maria B. Sukkar ◽

K. Fan Chung ◽

Bruce Jaffee ◽

Sha-Mei Liao ◽

...

Keyword(s):

Smooth Muscle ◽

Small Molecule ◽

Dominant Negative ◽

Iκb Kinase ◽

Airways Smooth Muscle ◽

Anti Inflammatory ◽

Human Airways

979: Urologic Complications of Diabetes: High Glucose-Induced Oxidative Stress Activates the Transcriptional Factor NF-KB in the Detrusor Smooth Muscle Cells

The Journal of Urology ◽

10.1016/s0022-5347(18)31207-2 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 324-324

Author(s):

Ettickan Boopathi ◽

Sunish Mohanan ◽

Zheng Yongmu ◽

Alan J. Wein ◽

Samuel Chacko

Keyword(s):

Oxidative Stress ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

High Glucose ◽

Muscle Cells ◽

Transcriptional Factor ◽

Detrusor Smooth Muscle ◽

Complications Of Diabetes ◽

Urologic Complications ◽

Detrusor Smooth Muscle Cells

Effects of high glucose concentrations and epalrestat on sorbitol and myo-inositol metabolism in cultured rabbit aortic smooth muscle cells

Diabetes ◽

10.2337/diabetes.42.11.1594 ◽

1993 ◽

Vol 42 (11) ◽

pp. 1594-1600 ◽

Cited By ~ 8

Author(s):

F. Sakakibara ◽

N. Hotta ◽

N. Koh ◽

N. Sakamoto

Keyword(s):

Smooth Muscle ◽

Smooth Muscle Cells ◽

High Glucose ◽

Muscle Cells ◽

Aortic Smooth Muscle Cells ◽

Aortic Smooth Muscle ◽

Inositol Metabolism

Resveratrol exerts antiproliferative effects on high-glucose-cultured vascular smooth muscle cells via inhibition of STAT3 and upregulation of mitochondrial gene GRIM-19 which is responsible for STAT3 activation

International Journal of Diabetes in Developing Countries ◽

10.1007/s13410-021-00963-3 ◽

2021 ◽

Author(s):

Yongguang Li ◽

Lijie Zhao ◽

Huixuan Zhou ◽

Beibei Han ◽

Haojun Yu ◽

...

Keyword(s):

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

High Glucose ◽

Mitochondrial Gene ◽

Muscle Cells ◽

Antiproliferative Effects

Abstract: P234 ROLE OF INSULIN SIGNALLING IN THE TRANSDIFFERENTIATION OF ENDOTHELIAL CELLS INTO SMOOTH MUSCLE CELLS INDUCED BY HIGH GLUCOSE

Atherosclerosis Supplements ◽

10.1016/s1567-5688(09)70299-5 ◽

2009 ◽

Vol 10 (2) ◽

pp. e299

Author(s):

Y Liu ◽

H Li ◽

J Zou

Keyword(s):

Endothelial Cells ◽

Smooth Muscle ◽

Smooth Muscle Cells ◽

High Glucose ◽

Insulin Signalling ◽

Muscle Cells

Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis

British Journal of Pharmacology ◽

10.1038/sj.bjp.0703452 ◽

2000 ◽

Vol 130 (7) ◽

pp. 1433-1452 ◽

Cited By ~ 119

Author(s):

Benjamin L J Webb ◽

Stuart J Hirst ◽

Mark A Giembycz

Keyword(s):

Smooth Muscle ◽

Protein Kinase C ◽

Protein Kinase ◽

Muscle Tone ◽

Smooth Muscle Tone ◽

Kinase C ◽

Airways Smooth Muscle ◽

Structure Regulation

Inhibition of NF-κB prevents high glucose-induced proliferation and plasminogen activator inhibitor-1 expression in vascular smooth muscle cells

Experimental & Molecular Medicine ◽

10.3858/emm.2011.43.12.079 ◽

2011 ◽

Vol 43 (12) ◽

pp. 684 ◽

Cited By ~ 29

Author(s):

In-Kyung Jeong ◽

Da Hee Oh ◽

Seung-Joon Park ◽

Ja-Heon Kang ◽

Sunshin Kim ◽

...

Keyword(s):

Smooth Muscle ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Plasminogen Activator ◽

Vascular Smooth Muscle Cells ◽

High Glucose ◽

Plasminogen Activator Inhibitor ◽

Muscle Cells ◽

Plasminogen Activator Inhibitor 1 ◽

Activator Inhibitor