Feature Selection Based on Gaussian Mixture Model Clustering for the Classification of Pulmonary Nodules Based on Computed Tomography

2020 ◽  
Vol 10 (5) ◽  
pp. 1033-1039
Author(s):  
Huihong Duan ◽  
Xu Wang ◽  
Xingyi He ◽  
Yonggang He ◽  
Litao Song ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Feature Selection ◽  
Gaussian Mixture Model ◽  
Mixture Model ◽  
Pulmonary Nodules ◽  
Gaussian Mixture ◽  
Local Optimum ◽  
Computer Aided ◽  
Aided Diagnosis

Background: In the pulmonary nodules computer aided diagnosis systems (CAD), feature selection plays an important role in reducing the false positive rate and improving the system accuracy. To solve the problem of feature selection techniques by which the diversity of features was damaged in the process of distinguishing malignant pulmonary nodules from benign pulmonary nodules, this study developed a novel feature selection algorithm for improving the accuracy of traditional computer-aided differential diagnosis for benign and malignant classification of pulmonary nodules. Method: Firstly, we divided the extracted features of nodules into several groups by using Gaussian mixture model (GMM). Secondly, we applied Relief and sequential forward selection (SFS) algorithm to find local optimum features dataset for each group. Afterwards, we used the optimumpath forest (OPF) classifier with the found features dataset to obtain the classification results. Finally, the local optimum features dataset with the highest area under curve AUC in all groups were added into the final selected set. Results: According to collected pulmonary nodules on computed tomography (CT) scans, tested with two set of samples, we achieved an average accuracy of 89.5%, sensitivity of 87.1% and specificity of 90.9% on the first set of samples, and 90.1%, 88.7% and 92.1% on the second set of samples. The areas under the receiver operating characteristic (ROC) curves based on these two sample sets were 95.2%, and 96.3% respectively. Conclusions: This study shows that the proposed method was promising for improving the pulmonary nodules computer aided diagnosis systems performance of benign and malignant pulmonary nodules.

Computer-aided diagnosis of pulmonary nodules using a two-step approach for feature selection and classifier ensemble construction

2010 ◽  
Vol 50 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Michael C. Lee ◽  
Lilla Boroczky ◽  
Kivilcim Sungur-Stasik ◽  
Aaron D. Cann ◽  
Alain C. Borczuk ◽  
...  
Keyword(s):  
Feature Selection ◽  
Pulmonary Nodules ◽  
Computer Aided Diagnosis ◽  
Classifier Ensemble ◽  
Computer Aided ◽  
Aided Diagnosis

scholarly journals Detection and Classification of Vehicles on Curved Roads

2019 ◽  
Vol 8 (10S) ◽  
pp. 152-156
Keyword(s):  
Object Detection ◽  
Gaussian Mixture Model ◽  
Mixture Model ◽  
Gaussian Mixture ◽  
Traffic Monitoring ◽  
Moving Object Detection ◽  
Morphological Operations ◽  
Moving Vehicles ◽  
Blob Analysis

Detection of a vehicle is a very important aspect for traffic monitoring. It is based on the concept of moving object detection. Classifying the detected object as vehicle and class of vehicle is also having application in various application domains. This paper aims at providing an application of vehicle detection and classification concept to detect vehicles along curved roads in Indian scenarios. The main purpose is to ensure safety in such roads. Gaussian mixture model and blob analysis are the methods applied for the detection of vehicles. Morphological operations are used to eliminate noise. The moving vehicles are detected and the class of the vehicle is identified.

Overview of Computer Aided Detection and Computer Aided Diagnosis Systems for Lung Nodule Detection in Computed Tomography

2020 ◽  
Vol 16 (1) ◽  
pp. 16-26 ◽  
Author(s):  
Shabana Rasheed Ziyad ◽  
Venkatachalam Radha ◽  
Thavavel Vayyapuri
Keyword(s):  
Computed Tomography ◽  
Review Paper ◽  
Lung Nodule ◽  
Lung Nodules ◽  
Computer Aided Detection ◽  
Lung Nodule Detection ◽  
Nodule Detection ◽  
Computer Aided ◽  
Aided Diagnosis

Background: Lung cancer has become a major cause of cancer-related deaths. Detection of potentially malignant lung nodules is essential for the early diagnosis and clinical management of lung cancer. In clinical practice, the interpretation of Computed Tomography (CT) images is challenging for radiologists due to a large number of cases. There is a high rate of false positives in the manual findings. Computer aided detection system (CAD) and computer aided diagnosis systems (CADx) enhance the radiologists in accurately delineating the lung nodules. Objectives: The objective is to analyze CAD and CADx systems for lung nodule detection. It is necessary to review the various techniques followed in CAD and CADx systems proposed and implemented by various research persons. This study aims at analyzing the recent application of various concepts in computer science to each stage of CAD and CADx. Methods: This review paper is special in its own kind because it analyses the various techniques proposed by different eminent researchers in noise removal, contrast enhancement, thorax removal, lung segmentation, bone suppression, segmentation of trachea, classification of nodule and nonnodule and final classification of benign and malignant nodules. Results: A comparison of the performance of different techniques implemented by various researchers for the classification of nodule and non-nodule has been tabulated in the paper. Conclusion: The findings of this review paper will definitely prove to be useful to the research community working on automation of lung nodule detection.

scholarly journals A New Computer-Aided Diagnosis System with Modified Genetic Feature Selection for BI-RADS Classification of Breast Masses in Mammograms

2020 ◽  
Vol 2020 ◽  
pp. 1-17 ◽  
Author(s):  
Said Boumaraf ◽  
Xiabi Liu ◽  
Chokri Ferkous ◽  
Xiaohong Ma
Keyword(s):  
Feature Selection ◽  
Predictive Value ◽  
Breast Imaging ◽  
Feature Selection Method ◽  
Computer Aided Diagnosis ◽  
Screening Mammography ◽  
Breast Masses ◽  
Computer Aided ◽  
Aided Diagnosis

Mammography remains the most prevalent imaging tool for early breast cancer screening. The language used to describe abnormalities in mammographic reports is based on the Breast Imaging Reporting and Data System (BI-RADS). Assigning a correct BI-RADS category to each examined mammogram is a strenuous and challenging task for even experts. This paper proposes a new and effective computer-aided diagnosis (CAD) system to classify mammographic masses into four assessment categories in BI-RADS. The mass regions are first enhanced by means of histogram equalization and then semiautomatically segmented based on the region growing technique. A total of 130 handcrafted BI-RADS features are then extracted from the shape, margin, and density of each mass, together with the mass size and the patient’s age, as mentioned in BI-RADS mammography. Then, a modified feature selection method based on the genetic algorithm (GA) is proposed to select the most clinically significant BI-RADS features. Finally, a back-propagation neural network (BPN) is employed for classification, and its accuracy is used as the fitness in GA. A set of 500 mammogram images from the digital database for screening mammography (DDSM) is used for evaluation. Our system achieves classification accuracy, positive predictive value, negative predictive value, and Matthews correlation coefficient of 84.5%, 84.4%, 94.8%, and 79.3%, respectively. To our best knowledge, this is the best current result for BI-RADS classification of breast masses in mammography, which makes the proposed system promising to support radiologists for deciding proper patient management based on the automatically assigned BI-RADS categories.

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