A Randomized Trial of the Effect of Soft Contact Lenses on Myopia Progression in Children

The goal of this retrospective case series is to demonstrate the effectivity of combination low-dose atropine therapy with peripheral defocus, double concentric circle design with a center distance soft contact lenses at controlling myopia progression over 1 year of treatment. Included in this series are 3 female children aged 8–10 years with progressing myopia averaging −4.37 ± 0.88 D at the beginning of treatment. Their average annual myopic progression during the 3 years prior to therapy was 1.12 ± 0.75 D. They had not attempted any myopia control treatments prior to this therapy. The children were treated with a combination of 0.01% atropine therapy with spherical peripheral defocus daily replacement soft lenses MiSight<sup>®</sup> 1 day (Cooper Vision, Phoenix, AZ, USA). They underwent cycloplegic refraction, and a slit-lamp evaluation every 6 months which confirmed no adverse reactions or staining was present. Each of the 3 children exhibited an average of 0.25 ± 0.25 D of myopia progression at the end of 1 year of treatment. To the best of the authors’ knowledge, this is the first published study exhibiting that combining low-dose atropine and peripheral defocus soft contact lenses is effective at controlling children’s moderate to severe myopia progression during 1 year of therapy.

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Myopiekontrolle: aktuelle Strategien

Optometry & Contact Lenses ◽

10.54352/dozv.ofnt2569 ◽

2021 ◽

Vol 1 (5) ◽

pp. 148-155

Keyword(s):

Contact Lenses ◽

Long Term Effects ◽

Soft Contact ◽

Myopia Progression ◽

Soft Contact Lenses ◽

Slowing Down ◽

The Future ◽

Progressive Myopia ◽

The Individual ◽

Myopia Control

Purpose. The prevalence of myopia is increasing worldwide and its long-term effects can have major impacts on eye health. Paediatric onset of myopia leads to a higher risk for developing high levels of myopia in adulthood. Slowing down or stopping myopia progression is an important task for the future. Material and Methods. Based on a literature review, the latest developments in the field of myopia control for children were summarized. The current study situation for orthokeratology, soft contact lenses, atropine therapy and spectacle lenses for the management of myopia is discussed in detail. Results. Results on the safety and effectiveness of orthokeratology and modified soft contact lenses are exceedingly consistent. Soft multifocal contact lenses, as well as newer spectacle lenses, recently received regulatory approval for myopia control. Studies on the administration of atropine recommend a dosage of 0.01 - 0.05 %. All methods slow down myopia progression and decrease axial length growth of the eye. Side effects, adverse events or discontinuation of treatment only occur in the rarest of cases. Orthokeratology and atropine continue to deliver the best results. Conclusion. From today’s perspective, carrying out myopia control can be recommended with great certainty. The choice of method depends on the individual requirements of each patient, with all methods offering success in reducing myopia progression. In the future, even more advanced contact lens geometries, more precise atropine dosages or improved optics of spectacle lenses will further increase the success of the treatment. Keywords. Progressive myopia, myopia control, children, contact lenses, atropine, spectacle lenses

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MYOPIA PROGRESSION WITH BIFOCAL SOFT CONTACT LENSES - A TWIN STUDY.

Optometry and Vision Science ◽

10.1097/00006324-200212001-00346 ◽

2002 ◽

Vol 79 (Supplement) ◽

pp. 179 ◽

Cited By ~ 1

Author(s):

Thomas Aller

Keyword(s):

Twin Study ◽

Contact Lenses ◽

Soft Contact ◽

Myopia Progression ◽

Soft Contact Lenses

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Effects of novel multifocal soft contact lens on peripheral refraction of myopic eyes when looking at distant and near targets

10.21203/rs.3.rs-20460/v1 ◽

2020 ◽

Author(s):

Fan Lu ◽

Xinjie Mao ◽

Shuyun Wen ◽

Liang Lin

Keyword(s):

Contact Lenses ◽

The Novel ◽

Soft Contact ◽

Myopia Progression ◽

Soft Contact Lenses ◽

Soft Contact Lens ◽

Long Time ◽

Hyperopic Shift ◽

Accommodative Lag ◽

Near Work

Abstract Background It is generally accepted the association between hyperopic peripheral defocus and myopia progression. To search for a good optical method to slow the myopia progression for the children who need long-time near work, we compared the effects of novel multifocal soft contact lenses (MFSCLs) with single vision soft contact lenses (SVSCLs) on peripheral refraction when looking at both distant and near targets. Methods The refraction of 25 young myopic subjects’ right eye were measured at horizontal retina eccentricities in 10º steps from 30º temporal to 30º nasal, with no correction (baseline), novel MFSCLs and SVSCLs when looking at distant (5 m) and near (0.4 m) targets. Results Subjects wearing MFSCLs presented significantly more myopic relative peripheral refractive error (RPRE) profile than SVSCLs at all horizontal retina eccentricities when looking at distant targets (all p<0.01). Compared with looking at distant targets, subjects wearing SVSCLs or MFSCLs showed a hyperopic shift of peripheral defocus when looking at near targets, owning to the effects of accommodative lag and hyperopic RPRE change during accommodation (except T20º and T30º wearing SVSCLs and N30º wearing MFSCLs, p=0.822, p=0.950, p=0.390, respectively, all other eccentricities p<0.05). But subjects wearing MFSCLs could still maintain a certain magnitude of myopic peripheral defocus at horizontal retina eccentricities when looking at near targets (T20° and T30°, p=0.023 and p<0.001, respectively). Conclusions The novel MFSCLs imposed strong myopic peripheral defocus when looking at distant targets. They also maintain a certain magnitude of myopic peripheral defocus when looking at near targets, regardless of the hyperopic effect of accommodation lag and hyperopic shift in RPRE during accommodation.

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Retardation of Myopia Progression by Multifocal Soft Contact Lenses

International Journal of Medical Sciences ◽

10.7150/ijms.30118 ◽

2019 ◽

Vol 16 (2) ◽

pp. 198-202 ◽

Cited By ~ 4

Author(s):

Qin Zhu ◽

Yongsong Liu ◽

Sean Tighe ◽

Yingting Zhu ◽

Xuanbo Su ◽

...

Keyword(s):

Contact Lenses ◽

Soft Contact ◽

Myopia Progression ◽

Soft Contact Lenses

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Effect of low-addition soft contact lenses with decentered optical design on myopia progression in children: a pilot study

Clinical Ophthalmology ◽

10.2147/opth.s66884 ◽

2014 ◽

pp. 1947 ◽

Cited By ~ 26

Author(s):

Takashi Fujikado ◽

Sayuri Ninomiya ◽

Takauma Kobayashi ◽

Asaki Suzaki ◽

Mitsuhiko Nakada ◽

...

Keyword(s):

Pilot Study ◽

Contact Lenses ◽

Optical Design ◽

Soft Contact ◽

Myopia Progression ◽

Soft Contact Lenses

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Clinical study on the effect of multifocal contact lenses on myopia progression in myopia school children

10.21203/rs.3.rs-240912/v1 ◽

2021 ◽

Author(s):

Osamu Hieda ◽

Yo Nakamura ◽

Takahiro Hiraoka ◽

Miho Kojima ◽

Tesuro Oshika ◽

...

Keyword(s):

Elementary School ◽

Clinical Study ◽

School Children ◽

Elementary School Children ◽

Contact Lenses ◽

Controlled Trial ◽

Soft Contact ◽

Myopia Progression ◽

Soft Contact Lenses ◽

Prospective Randomized Controlled Trial

Abstract Background: The efficacy of peripheral low add multifocal soft contact lenses for suppressing the progression of myopia is controversial. The aim of the on-going present clinical study is to investigate whether or not multifocal soft contact lenses with +0.50 D addition suppress the progression of myopia in myopic elementary school children.Design: Prospective randomized controlled trialSubjects and Methods: The study plans to include a total of 100 myopic school children. Target subjects are primary school male and female students with mild to moderate myopia. Children, who have eye related diseases other than myopia, are excluded from the study because they may affect the evaluation of the outcome. Subjects will be randomly assigned to wear daily disposable multifocal contact lenses with +0.50 D addition or daily disposable soft contact lenses. Subjects will wear contact lenses on both eyes and will be observed for two years under double-masked. Primary outcome is a change in the axial length over the two-year period. Objectives: The purpose of this study is to identify whether or not multifocal soft contact lenses with +0.5D addition suppress the progression of myopia in myopic elementary school children as compared with standard soft contact lenses.

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