scholarly journals Latest Updates on Antiretinal Autoantibodies Associated With Vision Loss and Breast Cancer

2015 ◽  
Vol 56 (3) ◽  
pp. 1680-1688 ◽  
Author(s):  
G. Adamus
Keyword(s):  
2019 ◽  
Vol 3 (4) ◽  
pp. 436-437
Author(s):  
David Lane ◽  
Kaila Pomeranz ◽  
Shannon Findlay ◽  
Daniel Miller

A 62-year-old woman with a history of metastatic breast cancer and known meningioma presented with unilateral vision loss associated with anisocoria and an afferent pupillary defect. On magnetic resonance imaging we found the cause to be optic nerve compression by a right frontal meningioma. Monocular vision-loss etiologies are anatomically localized to structures anterior to the optic chiasm. This case serves as a reminder that cerebral structures in this location must not be forgotten in the differential.


JAMA ◽  
2019 ◽  
Vol 322 (11) ◽  
pp. 1098
Author(s):  
Michael C. Izzo ◽  
Guri Bronner ◽  
Carol L. Shields
Keyword(s):  

2021 ◽  
Vol 3 (2) ◽  
pp. 113-119
Author(s):  
Joan Marie Palikat ◽  
Mimiwati Zahari ◽  
Eric Chung ◽  
Aliff Irwan Cheong ◽  
Norlina Ramli

Background: Isolated metastasis to the optic nerve (ON) and its sheath from breast cancer (BC) without involvement of other ocular structures is extremely rare. However, it is a pivotal diagnosis to rule out as it is a both sight- and life-threatening condition. We report a case of isolated ON sheath metastasis from BC presenting with central retinal vein occlusion (CRVO). Case presentation: A 47-year-old woman with known metastatic BC presented with painless, progressive vision loss in the left eye. Visual acuity was hand movement with ipsilateral relative afferent pupillary defect. Fundal features suggested CRVO. Atypical rapid resolution of these features led to suspect ON metastasis. Magnetic resonance of the brain showed perineural enhancement of the optic nerves. Vision improved with radiotherapy. Conclusion: Isolated ON sheath metastasis from BC is rare and may present with CRVO. High degree of suspicion is warranted in patients with metastatic disease and atypical findings.


Author(s):  
G. Kasnic ◽  
S. E. Stewart ◽  
C. Urbanski

We have reported the maturation of an intracisternal A-type particle in murine plasma cell tumor cultures and three human tumor cell cultures (rhabdomyosarcoma, lung adenocarcinoma, and osteogenic sarcoma) after IUDR-DMSO activation. In all of these studies the A-type particle seems to develop into a form with an electron dense nucleoid, presumably mature, which is also intracisternal. A similar intracisternal A-type particle has been described in leukemic guinea pigs. Although no biological activity has yet been demonstrated for these particles, on morphologic grounds, and by the manner in which they develop within the cell, they may represent members of the same family of viruses.


Author(s):  
John L. Swedo ◽  
R. W. Talley ◽  
John H. L. Watson

Since the report, which described the ultrastructure of a metastatic nodule of human breast cancer after estrogen therapy, additional ultrastructural observations, including some which are correlative with pertinent findings in the literature concerning mycoplasmas, have been recorded concerning the same subject. Specimen preparation was identical to that in.The mitochondria possessed few cristae, and were deteriorated and vacuolated. They often contained particulates and fibrous structures, sometimes arranged in spindle-shaped bundles, Fig. 1. Another apparent aberration was the occurrence, Fig. 2 (arrows) of linear profiles of what seems to be SER, which lie between layers of RER, and are often recognizably continuous with them.It was noted that the structure of the round bodies, interpreted as within autophagic vacuoles in the previous communication, and of vesicular bodies, described morphologically closely resembled those of some mycoplasmas. Specifically, they simulated or reflected the various stages of replication reported for mycoplasmas grown on solid nutrient. Based on this observation, they are referred to here as “mycoplasma-like” structures, in anticipation of confirmatory evidence from investigations now in progress.


2010 ◽  
Vol 34 (8) ◽  
pp. S49-S49
Author(s):  
Lei Wang ◽  
Xun Zhou ◽  
Lihong Zhou ◽  
Yong Chen ◽  
Xun Zhu ◽  
...  

2010 ◽  
Vol 34 (8) ◽  
pp. S47-S47
Author(s):  
Guopei Zheng ◽  
Sisi Yi ◽  
Yafei Li ◽  
Fangren Kong ◽  
Yanhui Yu ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A741-A741
Author(s):  
P ANG ◽  
D SCHRAG ◽  
K SCHNEIDER ◽  
K SHANNON ◽  
J JOHNSON ◽  
...  

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