scholarly journals Evidence for the involvement of interleukin 6 in experimental cancer cachexia.

1992 ◽  
Vol 89 (5) ◽  
pp. 1681-1684 ◽  
Author(s):  
G Strassmann ◽  
M Fong ◽  
J S Kenney ◽  
C O Jacob
Keyword(s):  
Interleukin 6 ◽  
Cancer Cachexia ◽  
Experimental Cancer

ROLE OF INTERLEUKIN-6 IN EXPERIMENTAL CANCER CACHEXIA

1993 ◽  
Vol 13 (1) ◽  
pp. 73 ◽  
Author(s):  
Gideon Strassmann
Keyword(s):  
Interleukin 6 ◽  
Cancer Cachexia ◽  
Experimental Cancer

scholarly journals Suramin interferes with interleukin-6 receptor binding in vitro and inhibits colon-26-mediated experimental cancer cachexia in vivo.

1993 ◽  
Vol 92 (5) ◽  
pp. 2152-2159 ◽  
Author(s):  
G Strassmann ◽  
M Fong ◽  
C E Freter ◽  
S Windsor ◽  
F D'Alessandro ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Interleukin 6 ◽  
Cancer Cachexia ◽  
Colon 26 ◽  
Experimental Cancer ◽  
Interleukin 6 Receptor

scholarly journals Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Jun Han ◽  
Qingyang Meng ◽  
Lei Shen ◽  
Guohao Wu
Keyword(s):  
Adipose Tissue ◽  
White Adipose Tissue ◽  
Interleukin 6 ◽  
Cancer Cachexia ◽  
Fat Loss ◽  
Adipose Tissue Lipolysis

Macrophage-derived tumor necrosis factor and tumor-derived of leukemia inhibitory factor and interleukin-6: Possible cellular mechanisms of cancer cachexia

1996 ◽  
Vol 3 (1) ◽  
pp. 29-35 ◽  
Author(s):  
Kevin G. Billingsley ◽  
Douglas L. Fraker ◽  
Gideon Strassmann ◽  
Caroline Loeser ◽  
Helen M. Fliot ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Interleukin 6 ◽  
Leukemia Inhibitory Factor ◽  
Tumor Necrosis ◽  
Cancer Cachexia ◽  
Inhibitory Factor ◽  
Cellular Mechanisms ◽  
Necrosis Factor

Complete reversal of muscle wasting in experimental cancer cachexia: Additive effects of activin type II receptor inhibition and β-2 agonist

2015 ◽  
Vol 138 (8) ◽  
pp. 2021-2029 ◽  
Author(s):  
Míriam Toledo ◽  
Sílvia Busquets ◽  
Fabio Penna ◽  
Xiaolan Zhou ◽  
Enrica Marmonti ◽  
...  
Keyword(s):  
Cancer Cachexia ◽  
Muscle Wasting ◽  
Type Ii ◽  
Additive Effects ◽  
Experimental Cancer ◽  
Receptor Inhibition ◽  
Complete Reversal

Experimental cancer cachexia: Evolving strategies for getting closer to the human scenario

2016 ◽  
Vol 54 ◽  
pp. 20-27 ◽  
Author(s):  
Fabio Penna ◽  
Sílvia Busquets ◽  
Josep M. Argilés
Keyword(s):  
Cancer Cachexia ◽  
Experimental Cancer

Experimental cachexia: effects of MCA sarcoma in the Fischer rat

1993 ◽  
Vol 265 (2) ◽  
pp. R376-R384 ◽  
Author(s):  
B. K. Smith ◽  
C. A. Conn ◽  
M. J. Kluger
Keyword(s):  
Weight Loss ◽  
Tumor Growth ◽  
Cancer Cachexia ◽  
Tumor Tissue ◽  
Experimental Period ◽  
Fischer 344 Rats ◽  
Fischer 344 ◽  
Experimental Cancer ◽  
Mca Sarcoma ◽  
Necrosis Factor

Temporal patterns of the cachectic effects of tumor growth and their relation to systemic levels of tumor necrosis factor (TNF) and IL-6 (interleukin-6) were examined in a rat model of experimental cancer cachexia employing the methylcholanthrene (MCA) sarcoma. Fischer 344 rats, implanted with biotelemeters for measuring temperature and activity, were implanted subdermally with tumor tissue fragments. Ad libitum-fed and pair-fed controls were sham incised. Bioassays for TNF and IL-6 were performed on serial plasma samples, obtained via jugular vein at 3- to 6-day intervals throughout the experimental period. Tumor growth induced significant anorexia, weight loss, and a decline in motor activity corresponding to an increase in mean plasma IL-6 levels, independent of reduced food intake or weight loss alone as shown in pair-fed controls. A significant lowering of body temperature then developed, followed by a two- to threefold increase in water consumption. The patterns of weight loss and temperature reduction differed in rate and degree from those seen with pair feeding.

scholarly journals Interference with Ca2+-Dependent Proteolysis Does Not Alter the Course of Muscle Wasting in Experimental Cancer Cachexia

2017 ◽  
Vol 8 ◽  
Author(s):  
Fabrizio Pin ◽  
Valerio G. Minero ◽  
Fabio Penna ◽  
Maurizio Muscaritoli ◽  
Roberta De Tullio ◽  
...  
Keyword(s):  
Cancer Cachexia ◽  
Muscle Wasting ◽  
Experimental Cancer

Cardiac Wasting in Experimental Cancer Cachexia: Prevention by Bisoprolol and Spironolactone

2011 ◽  
Vol 17 (8) ◽  
pp. S10
Author(s):  
Jochen Springer ◽  
Anika Tschirner ◽  
Arash Haghika ◽  
Aleksandra Grzesiak ◽  
Elena Kaschina ◽  
...  
Keyword(s):  
Cancer Cachexia ◽  
Experimental Cancer

scholarly journals Formoterol in the treatment of experimental cancer cachexia: effects on heart function

2014 ◽  
Vol 5 (4) ◽  
pp. 315-320 ◽  
Author(s):  
Míriam Toledo ◽  
Jochen Springer ◽  
Sílvia Busquets ◽  
Anika Tschirner ◽  
Francisco J. López-Soriano ◽  
...  
Keyword(s):  
Cancer Cachexia ◽  
Heart Function ◽  
Experimental Cancer
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