scholarly journals Effect of Knowledge of APOE Genotype on Subjective and Objective Memory Performance in Healthy Older Adults

2014 ◽  
Vol 171 (2) ◽  
pp. 201-208 ◽  
Author(s):  
Tara T. Lineweaver ◽  
Mark W. Bondi ◽  
Douglas Galasko ◽  
David P. Salmon
Keyword(s):  
Older Adults ◽  
Memory Performance ◽  
Apoe Genotype ◽  
Healthy Older Adults

P1-048: Knowledge of APOE genotype affects subjective and objective memory performance in healthy older adults

2012 ◽  
Vol 8 (4S_Part_3) ◽  
pp. P123-P124 ◽  
Author(s):  
David Salmon ◽  
Tara Lineweaver ◽  
Mark Bondi ◽  
Douglas Galasko
Keyword(s):  
Older Adults ◽  
Memory Performance ◽  
Apoe Genotype ◽  
Healthy Older Adults

The Impact of Stereotype Threat on Memory and Cognition in Older Adults

2021 ◽  
pp. 019394592110297
Author(s):  
Graham J. McDougall ◽  
Todd B. Monroe ◽  
Keenan A. Pituch ◽  
Michael A. Carter ◽  
Laurie Abbott
Keyword(s):  
Older Adults ◽  
Stereotype Threat ◽  
Verbal Memory ◽  
Memory Performance ◽  
Training Group ◽  
Memory Training ◽  
Unique Contribution ◽  
Healthy Older Adults ◽  
Bivariate Correlation ◽  
The Impact

Cultural stereotypes that equate aging with decreased competence and increased forgetfulness have persisted for decades. Stereotype threat (ST) refers to the psychological discomfort people experience when confronted by a negative, self-relevant stereotype in a situation where their behavior could be construed as confirming that belief. The purpose of this study was to examine the relationships of ST on memory performance in older adults over 24 months. The ST levels on average significantly declined, or improved in the memory training, but not the health training group. Although not significant at the .01 level, the bivariate correlation indicated that change in ST was moderately related to change in verbal memory, suggesting the possibility that improvements (or reductions) in ST may be related to increases in verbal memory scores. We discovered that the unique contribution of ST into the memory performance of healthy older adults offers a possible malleable trait.

Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults

Neurology ◽  
2012 ◽  
Vol 79 (16) ◽  
pp. 1645-1652 ◽  
Author(s):  
Y. Y. Lim ◽  
K. A. Ellis ◽  
R. H. Pietrzak ◽  
D. Ames ◽  
D. Darby ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Apoe Genotype ◽  
Healthy Older Adults ◽  
Amyloid Load

scholarly journals Wisdom and fluid intelligence are dissociable in healthy older adults

2021 ◽  
pp. 1-11
Author(s):  
Cutter A. Lindbergh ◽  
Heather Romero-Kornblum ◽  
Sophia Weiner-Light ◽  
J. Clayton Young ◽  
Corrina Fonseca ◽  
...  
Keyword(s):  
Older Adults ◽  
Episodic Memory ◽  
San Francisco ◽  
Fluid Intelligence ◽  
Memory Performance ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Self Report ◽  
Cross Sectional ◽  
Healthy Older Adults

ABSTRACT Objectives: The relationship between wisdom and fluid intelligence (Gf) is poorly understood, particularly in older adults. We empirically tested the magnitude of the correlation between wisdom and Gf to help determine the extent of overlap between these two constructs. Design: Cross-sectional study with preregistered hypotheses and well-powered analytic plan (https://osf.io/h3pjx). Setting: Memory and Aging Center at the University of California San Francisco, located in the USA. Participants: 141 healthy older adults (mean age = 76 years; 56% female). Measurements: Wisdom was quantified using a well-validated self-report-based scale (San Diego Wisdom Scale or SD-WISE). Gf was assessed via composite measures of processing speed (Gf-PS) and executive functioning (Gf-EF). The relationships of SD-WISE scores to Gf-PS and Gf-EF were tested in bivariate correlational analyses and multiple regression models adjusted for demographics (age, sex, and education). Exploratory analyses evaluated the relationships between SD-WISE and age, episodic memory performance, and dorsolateral and ventromedial prefrontal cortical volumes on magnetic resonance imaging. Results: Wisdom showed a small, positive association with Gf-EF (r = 0.181 [95% CI 0.016, 0.336], p = .031), which was reduced to nonsignificance upon controlling for demographics, and no association with Gf-PS (r = 0.019 [95% CI −0.179, 0.216], p = .854). Wisdom demonstrated a small, negative correlation with age (r = −0.197 [95% CI −0.351, −0.033], p = .019), but was not significantly related to episodic memory or prefrontal volumes. Conclusions: Our findings indicate that most of the variance in wisdom (>95%) is unaccounted for by Gf. The independence of wisdom from cognitive functions that reliably show age-associated declines suggests that it may hold unique potential to bolster decision-making, interpersonal functioning, and other everyday activities in older adults.

scholarly journals Prognostic Models for Changes in Memory Performance After Memory Training in Healthy Older Adults: a Systematic Review

2020 ◽  
Author(s):  
Mandy Roheger ◽  
Ann-Kristin Folkerts ◽  
Fabian Krohm ◽  
Nicole Skoetz ◽  
Elke Kalbe
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Prognostic Factors ◽  
Memory Performance ◽  
Prognostic Models ◽  
Memory Training ◽  
Long Term Memory ◽  
Healthy Older Adults ◽  
Short And Long Term ◽  
Future Outcomes

Abstract Identifying individuals’ profiles of prognostic factors that predict improvements after nonpharmacological interventions such as memory trainings may help to not only predict individuals’ future outcomes after such intervention, but also tailor new trainings for individuals with specific characteristics. However, until now, no systematic review on prognostic models, defined as a set of multiple prognostic factors to predict a future outcome, for changes in memory performance after memory training exist. MEDLINE, Web of Science Core Collection, CENTRAL, and PsycInfo were searched up to November 2019 to identify studies investigating prognostic models on verbal and non-verbal short- and long-term memory after conducting memory training in healthy older adults. The PROBAST tool was used to assess risk of bias. After screening n = 10,703 studies, n = 12 studies were included. These studies and the investigated statistical models are highly heterogeneous, so that conclusions are limited. However, one consistent result was that lower age combined with higher education seems to predict higher improvements after memory training. More studies on prognostic models for memory changes after memory training have to be conducted before clear conclusions which will help to tailor memory trainings to individuals’ profiles can be drawn. Registration: CRD42018105803, https://www.crd.york.ac.uk/PROSPERO

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