Relationship of Systolic Blood Pressure and Body Mass Index With Left Ventricular Mass and Mass Index in Adolescents

Background: Left ventricular hypertrophy is a forerunner of coronary heart disease, congestive cardiac failure, stroke and may also lead to sudden death. Estimation of left ventricular mass by echocardiography offers prognostic information better than the evaluation of traditional cardiovascular risk factors. Objective: The aim of this study was to determine the relative contributions of haemodynamic and metabolic factors affecting left ventricular mass in non-diabetic patients with essential hypertension. Material and methods: 100 non-diabetic hypertensive patients were taken. The association between age, gender, smoking, alcohol, height, weight, heart rate, clinic blood pressure, fasting blood glucose, lipid profile, haemoglobin, body mass index and stroke volume with LV mass was studied. Left ventricular mass was measured by using standard M-mode echocardiography measurement obtained by way of standard recommended by the American Society of Echocardiography. Results: Left ventricular mass was analyzed as a continuous variable. In males body mass index (r=.35, p<.004) and stroke volume(r=-.26, p<.039) were significantly correlated with LV mass. In females body weight was significantly related to left ventricular mass(r=.36, p<.02). The independent association between significant factors and left ventricular mass was assessed by stepwise multivariate logistic regression. Body mass index and systolic blood pressure came as independent determinants of left ventricular mass in all patients. A maximum of 13% of left ventricular mass variability could be explained by these two factors. Conclusion: In untreated patients with hypertension patient's body mass index and systolic blood pressure are independent predictors of left ventricular mass after adjustment for other haemodynamic and metabolic factors. They explain a maximum of 13% of left ventricular mass variability. More knowledge is needed about factors that may alter cardiac morphology in the evolution of hypertensive patients. Key words: Echocardiography; Haemodynamic; Metabolic Factors; Left Ventricular Mass; Non-diabetic; Hypertensive DOI: 10.3126/kumj.v8i2.3553 Kathmandu University Medical Journal (2010), Vol. 8, No. 2, Issue 30, 173-178

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Anger Types: Heritability and Relation to Blood Pressure, Body Mass Index, and Left Ventricular Mass

Journal of Clinical Hypertension ◽

10.1111/j.1751-7176.2008.00011.x ◽

2008 ◽

Vol 10 (9) ◽

pp. 700-706 ◽

Cited By ~ 3

Author(s):

Lillian Gleiberman ◽

Tiffany A. Greenwood ◽

Amy Luke ◽

Maria C. Delgado ◽

Alan B. Weder

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Left Ventricular Mass ◽

Body Mass ◽

Left Ventricular ◽

Ventricular Mass

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Relationship between Plasma Aldosterone Levels and Left Ventricular Mass in Hypertensive Africans

International Journal of Hypertension ◽

10.1155/2013/762597 ◽

2013 ◽

Vol 2013 ◽

pp. 1-6

Author(s):

Adewole Adebiyi ◽

Olubayo Akinosun ◽

Chibuike Nwafor ◽

Ayodele Falase

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Left Ventricular Mass ◽

Body Mass ◽

Plasma Renin ◽

Left Ventricular ◽

Plasma Aldosterone ◽

The Body ◽

Ventricular Mass ◽

Lv Mass

Background.Hypertension is the most common cardiovascular disease worldwide and is a major cause of morbidity and mortality. Studies have suggested that the activity of the renin-angiotensin-aldosterone system play a major role in the target organ damage such as left ventricular hypertrophy occuring in hypertension. We sought to determine the relationship between plasma aldosterone and left ventricular mass in untreated African hypertensives.Methods.We recruited 82 newly diagnosed and untreated hypertensives and 51 normal controls. Measurements obtained included echocardiographic LV mass index, plasma aldosterone and renin.Results.The hypertensive subjects had lower renin levels (21.03[6.974] versus 26.66[7.592] ng.mL−1,P=0.0013), higher LV mass index (52.56[14.483] versus 42.02[8.315] g.m−2.7P<0.0001) when compared with the controls. There were no univariate associations between LV mass index and plasma aldosterone (r=0.0179,P=0.57) and between LV mass index and plasma renin (r=0.0887,P=0.61). In a multivariate model involving LV mass index and age, sex, body mass index (BMI), plasma aldosterone, plasma renin and systolic blood pressure (SBP), only age (P=0.008), BMI (P=0.046), and SBP (P=0.001) were independently associated with the LV mass index.Conclusions. In this group of hypertensive Africans, there is no independent association of plasma aldosterone with LV mass. The height of the blood pressure, the body mass index and the age of the subjects determined the LV mass.

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