Role of Esophagoscopy in the Evaluation of Patients with Head and Neck Carcinoma

1983 ◽  
Vol 92 (4) ◽  
pp. 369-372 ◽  
Author(s):  
Thomas W. Grossman ◽  
Robert J. Toohill ◽  
James A. Duncavage ◽  
Roger H. Lehman ◽  
Thomas C. Malin
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Head And Neck Carcinoma ◽  
Barium Swallow ◽  
Second Primary ◽  
Special Focus ◽  
Neck Tumors ◽  
Neck Carcinoma

A retrospective study was conducted of 696 patients with squamous cell carcinoma of the head and neck seen over a 10-year period. Special focus was placed on secondary esophageal primaries in this group in an effort to define the role of esophagoscopy in the management of these patients. Second primary esophageal lesions were infrequently encountered (17 of 696, or 2.4% of the patients). Diagnostic accuracy of the esophagogram in a series of patients with index head and neck tumors and in a separate series of patients with index esophageal lesions was found to be high (98 + %). Based upon this study, we do not feel that esophagoscopy is always indicated as part of the initial workup for all head and neck cancer patients. Rather, we consider the barium swallow esophagogram to be a relatively safe and acceptably accurate alternative in most cases, with esophagoscopy reserved for specific indications.

scholarly journals Essential role of caspase-8 in p53/p73-dependent apoptosis induced by etoposide in head and neck carcinoma cells

2011 ◽  
Vol 10 (1) ◽  
pp. 95 ◽  
Author(s):  
Juan Liu ◽  
Hiroshi Uematsu ◽  
Nobuo Tsuchida ◽  
Masa-Aki Ikeda
Keyword(s):  
Head And Neck ◽  
Essential Role ◽  
Head And Neck Carcinoma ◽  
Carcinoma Cells ◽  
Caspase 8 ◽  
Neck Carcinoma

The role of lung resistance protein in radiation treated head and neck carcinoma

2006 ◽  
Vol 31 (3) ◽  
pp. 247-247
Author(s):  
P. Silva ◽  
N. Slevin ◽  
P. Sloan ◽  
P. Price ◽  
C. West ◽  
...  
Keyword(s):  
Head And Neck ◽  
Head And Neck Carcinoma ◽  
Lung Resistance Protein ◽  
Neck Carcinoma ◽  
Lung Resistance ◽  
Resistance Protein

The potential role of imaging techniques in avoiding neck dissection during salvage surgery after head and neck carcinoma treated with bioradiotherapy

2021 ◽  
Vol 135 (11) ◽  
pp. 970-975
Author(s):  
A Rovira ◽  
J Tornero ◽  
M Taberna ◽  
M Oliva ◽  
R Montal ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Head And Neck ◽  
Neck Dissection ◽  
Salvage Surgery ◽  
Head And Neck Carcinoma ◽  
Emission Tomography ◽  
Positron Emission ◽  
Neck Carcinoma

AbstractObjectiveThis study aimed to evaluate the effectiveness of computed tomography and positron emission tomography-computed tomography prior to salvage surgery after head and neck carcinoma treated with bioradiotherapy and to look at the role of neck dissection in this setting.MethodThis study was a retrospective chart review of a series of consecutive patients with locally advanced head and neck squamous cell carcinoma treated with bioradiotherapy. Radiological and pathological stages were compared to evaluate the accuracy of computed tomography and positron emission tomography-computed tomography in detecting occult neck metastasis in the context of recurrence of primary tumour. In order to assess the impact of neck dissection on survival, Kaplan–Meier survival curves after salvage surgery with and without neck dissection were derived.ResultsA total of 268 patients were identified, of which 22 underwent salvage surgery. The negative predictive value of computed tomography and positron emission tomography-computed tomography was excellent. Neck dissection did not represent an improvement on overall, disease specific and regional recurrence free survival (p = 0.67, p = 0.91 and p = 0.62, respectively) amongst clinically and radiologically negative necks.ConclusionConservative treatment of the neck should be considered when dealing with patients with primary site recurrence or persistent disease after bioradiotherapy without evidence of neck disease.

Second primary esophageal or lung cancer in patients with head and neck carcinoma in Taiwan: incidence and risk in relation to primary index tumor site

2010 ◽  
Vol 137 (1) ◽  
pp. 115-123 ◽  
Author(s):  
Min-Chi Chen ◽  
Ping-Tsung Chen ◽  
Chunghuang Hubert Chan ◽  
Cheng-Ta Yang ◽  
Chih-Cheng Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Head And Neck ◽  
Head And Neck Carcinoma ◽  
Second Primary ◽  
Tumor Site ◽  
Neck Carcinoma ◽  
Index Tumor ◽  
Primary Index

scholarly journals Cold Argon Plasma as Adjuvant Tumour Therapy on Progressive Head and Neck Cancer: A Preclinical Study

2019 ◽  
Vol 9 (10) ◽  
pp. 2061 ◽  
Author(s):  
Sybille Hasse ◽  
Christian Seebauer ◽  
Kristian Wende ◽  
Anke Schmidt ◽  
Hans-Robert Metelmann ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Viability ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Argon Plasma ◽  
Hacat Keratinocytes ◽  
Tumour Therapy

Investigating cold argon plasma (CAP) for medical applications is a rapidly growing, innovative field of research. The controllable supply of reactive oxygen and nitrogen species through CAP has the potential for utilization in tumour treatment. Maxillofacial surgery is limited if tumours grow on vital structures such as the arteria carotis. Here CAP could be considered as an option for adjuvant intraoperative tumour therapy especially in the case of squamous cell carcinoma of the head and neck. Further preclinical research is necessary to investigate the efficacy of this technology for future clinical applications in cancer treatment. Initially, a variety of in vitro assays was performed on two cell lines that served as surrogate for the squamous cell carcinoma (SCC) and healthy tissue, respectively. Cell viability, motility and the activation of apoptosis in SCC cells (HNO97) was compared with those in normal HaCaT keratinocytes. In addition, induction of apoptosis in ex vivo CAP treated human tissue biopsies of patients with tumours of the head and neck was monitored and compared to healthy control tissue of the same patient. In response to CAP treatment, normal HaCaT keratinocytes differed significantly from their malignant counterpart HNO97 cells in cell motility only whereas cell viability remained similar. Moreover, CAP treatment of tumour tissue induced more apoptotic cells than in healthy tissue that was accompanied by elevated extracellular cytochrome c levels. This study promotes a future role of CAP as an adjuvant intraoperative tumour therapy option in the treatment of head and neck cancer. Moreover, patient-derived tissue explants complement in vitro examinations in a meaningful way to reflect an antitumoral role of CAP.

Is there a role for flexible oesophagogastroscopy in upper aerodigestive tract squamous cell carcinoma?

2009 ◽  
Vol 124 (4) ◽  
pp. 417-419 ◽  
Author(s):  
T J Beech ◽  
M I Trotter ◽  
A L McDermott ◽  
W Mandal ◽  
A J Batch
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Patient Group ◽  
Squamous Cell ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract ◽  
Diagnostic Investigation

AbstractIntroduction:There is growing evidence to suggest that reflux (both laryngopharyngeal and gastroesophageal) has a role in the development of upper aerodigestive tract squamous cell carcinoma. This study discusses the role of identifying reflux in this patient group, and its prevalence.Methods:Prospective review of patients with head and neck cancer undergoing flexible oesophagogastroscopy as part of their diagnostic investigation.Results:Forty-five consecutive patients were identified. All patients were found to have evidence of oesophagitis, with 28 having oesophageal erosions and two Barrett's oesophagitis.Conclusion:Flexible oesophagogastroscopy is a useful test in patients with upper aerodigestive tract squamous cell carcinoma.

Role of neck dissection following concurrent chemoradiation for advanced head and neck carcinoma

Head & Neck ◽  
2006 ◽  
Vol 28 (12) ◽  
pp. 1099-1105 ◽  
Author(s):  
Véronique-Isabelle Forest ◽  
Phuc Félix Nguyen-Tan ◽  
Jean-Claude Tabet ◽  
Marie-Jo Olivier ◽  
Daniel Larochelle ◽  
...  
Keyword(s):  
Head And Neck ◽  
Neck Dissection ◽  
Head And Neck Carcinoma ◽  
Concurrent Chemoradiation ◽  
Advanced Head ◽  
Neck Carcinoma
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