Three Healthy Eating Patterns and Cardiovascular Disease Risk Markers in 9 to 18 Year Olds With Body Mass Index >95%: A Randomized Trial

2021 ◽  
Vol 60 (11-12) ◽  
pp. 474-484
Author(s):  
Michael Macknin ◽  
Nicole Stegmeier ◽  
Alicia Thomas ◽  
Sarah Worley ◽  
Lin Li ◽  
...  

Approximately 20% of American 9 to 18 year olds are obese, and most carry their excess adiposity, with its associated increased risk for cardiovascular disease, into adulthood. We studied cardiovascular disease risk markers changes associated with 3 healthy eating patterns (HEPs) in 96 9 to 18 year olds with a body mass index >95% in a Midwestern health system 1-year randomized trial. All HEPs were associated with similar statistically significant ( P < .05 to <.001) cardiovascular disease risk marker improvements in weight, systolic and diastolic blood pressure, total cholesterol, low-density lipoprotein, and myeloperoxidase. Time required was the only identified significant ( P < .001) deterrent from enrolling in study. These HEPs had characteristics common to most HEPs: encouraging whole foods, fruits and vegetables, whole grains, beans other legumes, and limiting added salt, saturated fatty acids, added sugars, red meat, processed meats, and other processed foods. Further research on initiatives to ease the time burden, and increase implementation of established healthy eating principles is needed.

2020 ◽  
pp. 135910531990128 ◽  
Author(s):  
Neha A John-Henderson ◽  
Courtney S Tintzman ◽  
Cory J Counts ◽  
Claudia M Mueller

American Indians are at increased risk for cardiovascular disease in adulthood, and levels of physical activity and body mass index associate with cardiovascular disease risk. Recent research indicates that one’s mindset may play a role in determining health behaviors and outcomes. In a sample of 105 American Indian college students, greater growth health mindset associated with lower body mass index. Bootstrapping analyses revealed a significant indirect effect of health mindset on body mass index through levels of physical activity. These findings suggest that interventions aiming to promote growth health mindsets may be successful in reducing risk for cardiovascular disease in American Indian college students.


Author(s):  
Maria J. Iglesias ◽  
Larissa D. Kruse ◽  
Laura Sanchez-Rivera ◽  
Linnea Enge ◽  
Philip Dusart ◽  
...  

Objective: Endothelial cell (EC) dysfunction is a well-established response to cardiovascular disease risk factors, such as smoking and obesity. Risk factor exposure can modify EC signaling and behavior, leading to arterial and venous disease development. Here, we aimed to identify biomarker panels for the assessment of EC dysfunction, which could be useful for risk stratification or to monitor treatment response. Approach and Results: We used affinity proteomics to identify EC proteins circulating in plasma that were associated with cardiovascular disease risk factor exposure. Two hundred sixteen proteins, which we previously predicted to be EC-enriched across vascular beds, were measured in plasma samples (n=1005) from the population-based SCAPIS (Swedish Cardiopulmonary Bioimage Study) pilot. Thirty-eight of these proteins were associated with body mass index, total cholesterol, low-density lipoprotein, smoking, hypertension, or diabetes. Sex-specific analysis revealed that associations predominantly observed in female- or male-only samples were most frequently with the risk factors body mass index, or total cholesterol and smoking, respectively. We show a relationship between individual cardiovascular disease risk, calculated with the Framingham risk score, and the corresponding biomarker profiles. Conclusions: EC proteins in plasma could reflect vascular health status.


2011 ◽  
Vol 55 (6) ◽  
pp. 427-427 ◽  
Author(s):  
Gabriel Gustavo Bergmann ◽  
Mauren Lúcia de Araújo Bergmann ◽  
Ricardo Rodrigo Rech ◽  
Cristine Boone Constanzi ◽  
Lidiane Requia Alli ◽  
...  

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