scholarly journals A Two-Level Alternating Direction Model for Polytomous Items With Local Dependence

2019 ◽  
Vol 80 (2) ◽  
pp. 293-311
Author(s):  
Igor Himelfarb ◽  
Katerina M. Marcoulides ◽  
Guoliang Fang ◽  
Bruce L. Shotts

The chiropractic clinical competency examination uses groups of items that are integrated by a common case vignette. The nature of the vignette items violates the assumption of local independence for items nested within a vignette. This study examines via simulation a new algorithmic approach for addressing the local independence violation problem using a two-level alternating directions testlet model. Parameter values for item difficulty, discrimination, test-taker ability, and test-taker secondary abilities associated with a particular testlet are generated and parameter recovery through Markov Chain Monte Carlo Bayesian methods and generalized maximum likelihood estimation methods are compared. To aid with the complex computational efforts, the novel so-called TensorFlow platform is used. Both estimation methods provided satisfactory parameter recovery, although the Bayesian methods were found to be somewhat superior in recovering item discrimination parameters. The practical significance of the results are discussed in relation to obtaining accurate estimates of item, test, ability parameters, and measurement reliability information.

Author(s):  
Anne Krogh Nøhr ◽  
Kristian Hanghøj ◽  
Genis Garcia Erill ◽  
Zilong Li ◽  
Ida Moltke ◽  
...  

Abstract Estimation of relatedness between pairs of individuals is important in many genetic research areas. When estimating relatedness, it is important to account for admixture if this is present. However, the methods that can account for admixture are all based on genotype data as input, which is a problem for low-depth next-generation sequencing (NGS) data from which genotypes are called with high uncertainty. Here we present a software tool, NGSremix, for maximum likelihood estimation of relatedness between pairs of admixed individuals from low-depth NGS data, which takes the uncertainty of the genotypes into account via genotype likelihoods. Using both simulated and real NGS data for admixed individuals with an average depth of 4x or below we show that our method works well and clearly outperforms all the commonly used state-of-the-art relatedness estimation methods PLINK, KING, relateAdmix, and ngsRelate that all perform quite poorly. Hence, NGSremix is a useful new tool for estimating relatedness in admixed populations from low-depth NGS data. NGSremix is implemented in C/C ++ in a multi-threaded software and is freely available on Github https://github.com/KHanghoj/NGSremix.


Axioms ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 25 ◽  
Author(s):  
Ehab Almetwally ◽  
Randa Alharbi ◽  
Dalia Alnagar ◽  
Eslam Hafez

This paper aims to find a statistical model for the COVID-19 spread in the United Kingdom and Canada. We used an efficient and superior model for fitting the COVID 19 mortality rates in these countries by specifying an optimal statistical model. A new lifetime distribution with two-parameter is introduced by a combination of inverted Topp-Leone distribution and modified Kies family to produce the modified Kies inverted Topp-Leone (MKITL) distribution, which covers a lot of application that both the traditional inverted Topp-Leone and the modified Kies provide poor fitting for them. This new distribution has many valuable properties as simple linear representation, hazard rate function, and moment function. We made several methods of estimations as maximum likelihood estimation, least squares estimators, weighted least-squares estimators, maximum product spacing, Crame´r-von Mises estimators, and Anderson-Darling estimators methods are applied to estimate the unknown parameters of MKITL distribution. A numerical result of the Monte Carlo simulation is obtained to assess the use of estimation methods. also, we applied different data sets to the new distribution to assess its performance in modeling data.


Stats ◽  
2019 ◽  
Vol 2 (2) ◽  
pp. 247-258 ◽  
Author(s):  
Pedro L. Ramos ◽  
Francisco Louzada

A new one-parameter distribution is proposed in this paper. The new distribution allows for the occurrence of instantaneous failures (inliers) that are natural in many areas. Closed-form expressions are obtained for the moments, mean, variance, a coefficient of variation, skewness, kurtosis, and mean residual life. The relationship between the new distribution with the exponential and Lindley distributions is presented. The new distribution can be viewed as a combination of a reparametrized version of the Zakerzadeh and Dolati distribution with a particular case of the gamma model and the occurrence of zero value. The parameter estimation is discussed under the method of moments and the maximum likelihood estimation. A simulation study is performed to verify the efficiency of both estimation methods by computing the bias, mean squared errors, and coverage probabilities. The superiority of the proposed distribution and some of its concurrent distributions are tested by analyzing four real lifetime datasets.


2012 ◽  
Vol 4 (1) ◽  
pp. 185
Author(s):  
Irfan Wahyudi ◽  
Purhadi Purhadi ◽  
Sutikno Sutikno ◽  
Irhamah Irhamah

Multivariate Cox proportional hazard models have ratio property, that is the ratio of  hazard functions for two individuals with covariate vectors  z1 and  z2 are constant (time independent). In this study we talk about estimation of prameters on multivariate Cox model by using Maximum Partial Likelihood Estimation (MPLE) method. To determine the appropriate estimators  that maximize the ln-partial likelihood function, after a score vector and a Hessian matrix are found, numerical iteration methods are applied. In this case, we use a Newton Raphson method. This numerical method is used since the solutions of the equation system of the score vector after setting it equal to zero vector are not closed form. Considering the studies about multivariate Cox model are limited, including the parameter estimation methods, but the methods are urgently needed by some fields of study related such as economics, engineering and medical sciences. For this reasons, the goal of this study is designed to develop parameter estimation methods from univariate to multivariate cases.


2022 ◽  
Vol 7 (2) ◽  
pp. 2820-2839
Author(s):  
Saurabh L. Raikar ◽  
◽  
Dr. Rajesh S. Prabhu Gaonkar ◽  

<abstract> <p>Jaya algorithm is a highly effective recent metaheuristic technique. This article presents a simple, precise, and faster method to estimate stress strength reliability for a two-parameter, Weibull distribution with common scale parameters but different shape parameters. The three most widely used estimation methods, namely the maximum likelihood estimation, least squares, and weighted least squares have been used, and their comparative analysis in estimating reliability has been presented. The simulation studies are carried out with different parameters and sample sizes to validate the proposed methodology. The technique is also applied to real-life data to demonstrate its implementation. The results show that the proposed methodology's reliability estimates are close to the actual values and proceeds closer as the sample size increases for all estimation methods. Jaya algorithm with maximum likelihood estimation outperforms the other methods regarding the bias and mean squared error.</p> </abstract>


Mathematics ◽  
2020 ◽  
Vol 8 (10) ◽  
pp. 1648
Author(s):  
Mohamed Aboraya ◽  
Haitham M. Yousof ◽  
G.G. Hamedani ◽  
Mohamed Ibrahim

In this work, we propose and study a new family of discrete distributions. Many useful mathematical properties, such as ordinary moments, moment generating function, cumulant generating function, probability generating function, central moment, and dispersion index are derived. Some special discrete versions are presented. A certain special case is discussed graphically and numerically. The hazard rate function of the new class can be “decreasing”, “upside down”, “increasing”, and “decreasing-constant-increasing (U-shape)”. Some useful characterization results based on the conditional expectation of certain function of the random variable and in terms of the hazard function are derived and presented. Bayesian and non-Bayesian methods of estimation are considered. The Bayesian estimation procedure under the squared error loss function is discussed. Markov chain Monte Carlo simulation studies for comparing non-Bayesian and Bayesian estimations are performed using the Gibbs sampler and Metropolis–Hastings algorithm. Four applications to real data sets are employed for comparing the Bayesian and non-Bayesian methods. The importance and flexibility of the new discrete class is illustrated by means of four real data applications.


Sensors ◽  
2019 ◽  
Vol 19 (2) ◽  
pp. 339 ◽  
Author(s):  
Yongsong Li ◽  
Zhengzhou Li ◽  
Kai Wei ◽  
Weiqi Xiong ◽  
Jiangpeng Yu ◽  
...  

Noise estimation for image sensor is a key technique in many image pre-processing applications such as blind de-noising. The existing noise estimation methods for additive white Gaussian noise (AWGN) and Poisson-Gaussian noise (PGN) may underestimate or overestimate the noise level in the situation of a heavy textured scene image. To cope with this problem, a novel homogenous block-based noise estimation method is proposed to calculate these noises in this paper. Initially, the noisy image is transformed into the map of local gray statistic entropy (LGSE), and the weakly textured image blocks can be selected with several biggest LGSE values in a descending order. Then, the Haar wavelet-based local median absolute deviation (HLMAD) is presented to compute the local variance of these selected homogenous blocks. After that, the noise parameters can be estimated accurately by applying the maximum likelihood estimation (MLE) to analyze the local mean and variance of selected blocks. Extensive experiments on synthesized noised images are induced and the experimental results show that the proposed method could not only more accurately estimate the noise of various scene images with different noise levels than the compared state-of-the-art methods, but also promote the performance of the blind de-noising algorithm.


Endocrinology ◽  
2019 ◽  
Vol 160 (10) ◽  
pp. 2395-2400 ◽  
Author(s):  
David J Handelsman ◽  
Lam P Ly

Abstract Hormone assay results below the assay detection limit (DL) can introduce bias into quantitative analysis. Although complex maximum likelihood estimation methods exist, they are not widely used, whereas simple substitution methods are often used ad hoc to replace the undetectable (UD) results with numeric values to facilitate data analysis with the full data set. However, the bias of substitution methods for steroid measurements is not reported. Using a large data set (n = 2896) of serum testosterone (T), DHT, estradiol (E2) concentrations from healthy men, we created modified data sets with increasing proportions of UD samples (≤40%) to which we applied five different substitution methods (deleting UD samples as missing and substituting UD sample with DL, DL/√2, DL/2, or 0) to calculate univariate descriptive statistics (mean, SD) or bivariate correlations. For all three steroids and for univariate as well as bivariate statistics, bias increased progressively with increasing proportion of UD samples. Bias was worst when UD samples were deleted or substituted with 0 and least when UD samples were substituted with DL/√2, whereas the other methods (DL or DL/2) displayed intermediate bias. Similar findings were replicated in randomly drawn small subsets of 25, 50, and 100. Hence, we propose that in steroid hormone data with ≤40% UD samples, substituting UD with DL/√2 is a simple, versatile, and reasonably accurate method to minimize left censoring bias, allowing for data analysis with the full data set.


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