scholarly journals Contribution of the PDL to Osteotomy Repair and Implant Osseointegration

2017 ◽  
Vol 96 (8) ◽  
pp. 909-916 ◽  
Author(s):  
X. Pei ◽  
L. Wang ◽  
C. Chen ◽  
X. Yuan ◽  
Q. Wan ◽  
...  
Keyword(s):  
Bone Formation ◽  
Titanium Implants ◽  
Multiple Time ◽  
New Bone Formation ◽  
Extraction Socket ◽  
Minimally Invasive Surgical ◽  
Implant Placement ◽  
Extraction Site ◽  
Immediate Implants ◽  
Immediate Implant

Our objective was to clarify the fate of the periodontal ligament (PDL) retained in the socket after tooth extraction, then determine if this tissue contributed to the osseointegration of “immediate” implants placed in these fresh extraction sockets. Mice underwent maxillary first molar extraction, the residual PDL was removed by an osteotomy, and titanium implants were placed. The osteotomy was created in such a way that the palatal surface was devoid of PDL remnants while the buccal, mesial, and distal surfaces retained PDL fibers. At multiple time points after surgery, tissues were analyzed using a battery of molecular, cellular, and histomorphometrical assays. We found that PDL remnants mineralized and directly contributed to new bone formation in the extraction site. Compared with regions of an extraction site where the PDL was removed by osteotomy, regions that retained PDL fibers had produced significantly more new bone. Around immediate implants, the retained PDL remnants directly contributed to new bone formation and osseointegration. Thus, we conclude that PDL remnants are inherently osteogenic, and if the tissue is healthy, it is reasonable to conclude that curetting out an extraction socket prior to immediate implant placement should be avoided. This recommendation aligns with contemporary trends toward minimally invasive surgical manipulations of the extraction socket prior to immediate implant placement.

Prevalence of favourable anatomy for palatal emergence of an immediate implant in the maxillary central incisor post-extraction site.

2021 ◽  
Author(s):  
andoni jones ◽  
david chávarri-prado ◽  
markel diéguez-pereira ◽  
alejandro estrada-martínez ◽  
miguel beltrán-guijarro ◽  
...  
Keyword(s):  
Minimum Distance ◽  
Central Incisor ◽  
Anatomical Structures ◽  
3D Images ◽  
Maxillary Central Incisor ◽  
Implant Placement ◽  
Planning Software ◽  
Extraction Site ◽  
Immediate Implants ◽  
Immediate Implant

The purpose of this study was to determine the prevalence of favourable anatomy for palatal emergence of an immediate flapless implant in the maxillary central incisor post-extraction site. Implants were virtually placed into maxillary central incisor sites using 3D implant planning software. Following a strict implant placement criteria to keep a safety distance to the buccal plate and other anatomical structures, sockets where assessed to determine their suitability for a palatally emerging implant. From 321 patients included in this study, 62.3% presented a suitable socket anatomy for an immediate implant to be placed with the angulation for a screw retained crown. In 29% of the cases, the implants had to be labially tilted to keep a minimum distance to the buccal plate. 8.7% were unsuitable for immediate implants due to anatomic limitations. The position and angulation for an implant  in  the  maxillary  central  incisor  socket  should  be  carefully  assessed  preoperatively  with  3D  images,  as  many  sites  will  not  be  candidates  for  a  palatal  emergence and thus, a  screw  retained  restoration.

scholarly journals Biomechanics of Immediate Postextraction Implant Osseointegration

2018 ◽  
Vol 97 (9) ◽  
pp. 987-994 ◽  
Author(s):  
X. Yuan ◽  
X. Pei ◽  
Y. Zhao ◽  
Z. Li ◽  
C.H. Chen ◽  
...  
Keyword(s):  
Finite Element ◽  
Bone Formation ◽  
Finite Element Modeling ◽  
Direct Contact ◽  
Osteotomy Site ◽  
New Bone Formation ◽  
Element Modeling ◽  
Implant Placement ◽  
Osteocyte Death ◽  
Immediate Implant

The aim of this study was to gain insights into the biology and mechanics of immediate postextraction implant osseointegration. To mimic clinical practice, murine first molar extraction was followed by osteotomy site preparation, specifically in the palatal root socket. The osteotomy was positioned such that it removed periodontal ligament (PDL) only on the palatal aspect of the socket, leaving the buccal aspect undisturbed. This strategy created 2 distinct peri-implant environments: on the palatal aspect, the implant was in direct contact with bone, while on the buccal aspect, a PDL-filled gap existed between the implant and bone. Finite element modeling showed high strains on the palatal aspect, where bone was compressed by the implant. Osteocyte death and bone resorption predominated on the palatal aspect, leading to the loss of peri-implant bone. On the buccal aspect, where finite element modeling revealed low strains, there was minimal osteocyte death and robust peri-implant bone formation. Initially, the buccal aspect was filled with PDL remnants, which we found directly provided Wnt-responsive cells that were responsible for new bone formation and osseointegration. On the palatal aspect, which was devoid of PDL and Wnt-responsive cells, adding exogenous liposomal WNT3A created an osteogenic environment for rapid peri-implant bone formation. Thus, we conclude that low strain and high Wnt signaling favor osseointegration of immediate postextraction implants. The PDL harbors Wnt-responsive cells that are inherently osteogenic, and if the PDL tissue is healthy, it is reasonable to preserve this tissue during immediate implant placement.

scholarly journals In Vivo Study for Clinical Application of Dental Stem Cell Therapy Incorporated with Dental Titanium Implants

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 381
Author(s):  
Hyunmin Choi ◽  
Kyu-Hyung Park ◽  
Narae Jung ◽  
June-Sung Shim ◽  
Hong-Seok Moon ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Formation ◽  
Alveolar Bone ◽  
Human Mesenchymal Stem Cells ◽  
Titanium Implants ◽  
Osteogenic Potential ◽  
Induction Medium ◽  
Radiographic Analysis ◽  
New Bone Formation

The aim of this study was to investigate the behavior of dental-derived human mesenchymal stem cells (d-hMSCs) in response to differently surface-treated implants and to evaluate the effect of d-hMSCs on local osteogenesis around an implant in vivo. d-hMSCs derived from alveolar bone were established and cultured on machined, sandblasted and acid-etched (SLA)-treated titanium discs with and without osteogenic induction medium. Their morphological and osteogenic potential was assessed by scanning electron microscopy (SEM) and real-time polymerase chain reaction (RT-PCR) via mixing of 5 × 106 of d-hMSCs with 1 mL of Metrigel and 20 μL of gel-cell mixture, which was dispensed into the defect followed by the placement of customized mini-implants (machined, SLA-treated implants) in New Zealand white rabbits. Following healing periods of 2 weeks and 12 weeks, the obtained samples in each group were analyzed radiographically, histomorphometrically and immunohistochemically. The quantitative change in osteogenic differentiation of d-hMSCs was identified according to the type of surface treatment. Radiographic analysis revealed that an increase in new bone formation was statistically significant in the d-hMSCs group. Histomorphometric analysis was in accordance with radiographic analysis, showing the significantly increased new bone formation in the d-hMSCs group regardless of time of sacrifice. Human nuclei A was identified near the area where d-hMSCs were implanted but the level of expression was found to be decreased as time passed. Within the limitations of the present study, in this animal model, the transplantation of d-hMSCs enhanced the new bone formation around an implant and the survival and function of the stem cells was experimentally proven up to 12 weeks post-sacrifice.

scholarly journals Diagnosis and treatment of extraction sockets in preparation for implant placement: report of three cases

2008 ◽  
Vol 19 (2) ◽  
pp. 159-164 ◽  
Author(s):  
Márcio José Rodrigues Barcelos ◽  
Arthur Belém Novaes Júnior ◽  
Marcio Baltazar Conz ◽  
Nassin David Harari ◽  
Guaracilei Maciel Vidigal Júnior
Keyword(s):  
Bone Defect ◽  
Root Resorption ◽  
Case Reports ◽  
Receptor Site ◽  
Wall Defect ◽  
Implant Placement ◽  
Immediate Implants ◽  
Immediate Implant ◽  
Defect Morphology ◽  
Subsequent Intervention

This article addresses diagnostic parameters that should be assessed in the treatment of extraction sockets with dental implant placement by presenting three case reports that emphasize the relevance of the amount of remaining bone walls. Diagnosis was based on the analysis of clinical and radiographic parameters (e.g.: bone defect morphology, remaining bone volume, presence of infections on the receptor site). Case 1 presents a 5-wall defect in the maxillary right central incisor region with severe root resorption, which was treated with immediate implant placement. Cases 2 and 3 present, respectively, two- and three-wall bone defects that did not have indication for immediate implants. These cases were first submitted to a guided bone regeneration (GBR) procedure with bone graft biomaterial and membrane barriers, and the implants were installed in a second surgical procedure. The analysis of the preoperative periodontal condition of the adjacent teeth and bone defect morphology is extremely important because these factors determine the choice between immediate implant or GBR treatment followed by implant installation in a subsequent intervention.

scholarly journals Immediate Implant Placement by Interradicular Bone Drilling before Molar Extraction: Clinical Case Report with One-Year Follow-Up

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Stuardo Valenzuela ◽  
José M. Olivares ◽  
Nicolás Weiss ◽  
Dafna Benadof
Keyword(s):  
Survival Rates ◽  
Three Dimensional ◽  
Primary Stability ◽  
Bone Drilling ◽  
Implant Placement ◽  
Immediate Implants ◽  
Immediate Implant ◽  
One Year ◽  
Molar Extraction

The placement of immediate implants in the posterior sector is a widespread procedure where the success and survival rates are similar to those of traditional protocols. It has several anatomical challenges, such as the presence of interradicular bone septa that hinder a correct three-dimensional positioning of the implant and may compromise primary stability and/or cause damage of neighboring structures. The aim of this article is to present the treatment and the one-year clinical follow-up of a patient who received immediate implant placement using an interradicular bone-drilling technique before the molar extraction.

Guidelines for Selecting the Implant Diameter During Immediate Implant Placement of a Fresh Extraction Socket: A Case Series

2016 ◽  
Vol 36 (3) ◽  
pp. 401-407 ◽  
Author(s):  
Ariádene Pértile de Oliveira Rosa ◽  
José Martins da Rosa ◽  
Luís Pereira ◽  
Carlos Francischone ◽  
Bruno Sotto-Maior
Keyword(s):  
Case Series ◽  
Extraction Socket ◽  
Implant Placement ◽  
Immediate Implant

scholarly journals A Novel HA/β-TCP-Collagen Composite Enhanced New Bone Formation for Dental Extraction Socket Preservation in Beagle Dogs

Materials ◽  
2016 ◽  
Vol 9 (3) ◽  
pp. 191 ◽  
Author(s):  
Ko-Ning Ho ◽  
Eisner Salamanca ◽  
Kuo-Chi Chang ◽  
Tsai-Chin Shih ◽  
Yu-Chi Chang ◽  
...  
Keyword(s):  
Bone Formation ◽  
Dental Extraction ◽  
New Bone Formation ◽  
Beagle Dogs ◽  
Extraction Socket ◽  
Socket Preservation

Fresh extraction socket: spontaneous healing vs. immediate implant placement

2014 ◽  
Vol 26 (11) ◽  
pp. 1250-1255 ◽  
Author(s):  
Nicola Discepoli ◽  
Fabio Vignoletti ◽  
Luigi Laino ◽  
Massimo de Sanctis ◽  
Fernando Muñoz ◽  
...  
Keyword(s):  
Spontaneous Healing ◽  
Extraction Socket ◽  
Implant Placement ◽  
Immediate Implant

Can Time of Implant Placement influence Bone Remodeling?

2016 ◽  
Vol 17 (4) ◽  
pp. 270-274
Author(s):  
Caroline Freitas Rafael ◽  
Bernardo Passoni ◽  
Carlos Araújo ◽  
Maria A de Araújo ◽  
César Benfatti ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Remodeling ◽  
Healing Process ◽  
Bone Architecture ◽  
Implant Placement ◽  
Equal Rate ◽  
Average Analysis ◽  
Immediate Implants ◽  
Group 2 ◽  
Group 1

ABSTRACT Since the alveolar process is tissue “dental dependent,” after the extraction of the dental element, this process suffers some degree of atrophy during the healing process, which can be reduced with the installation of immediate implants, aiming to maintain the original bone architecture. The aim of this study was to investigate the influence of the time of implant placement on bone formation around them. Seven dogs were selected and randomly divided into two groups: Group 1, where implants were placed immediately after extraction of two lower premolars without flap elevation, and group 2, where implants were delayed by 4 months after extractions. Each group received 14 implants, and 4 months after the second surgery, the samples were processed and analyzed histomorphometrically. A mean average analysis and the Kruskal–Wallis test (p < 0.05) were performed. The buccal bone–implant contact (BIC) mean average was found larger in immediate implants (42.61%) compared with delayed implants (37.69%). Group 1 had statistically higher outcomes in bone formation and BIC on the buccal bone wall. It was concluded that performing immediate implants with the palatal approach technique and leaving a buccal GAP enables a higher or at least equal rate to BIC and bone area around them, when compared with delayed implants. Actually, the patients and dentists want to do a shorter treatment with satisfactory results, but it is necessary to understand whether different times of implant placement can influence the results and longevity of the treatment. How to cite this article Rafael CF, Passoni B, Araújo C, de Araújo MA, Benfatti C, Volpato C. Can Time of Implant Placement influence Bone Remodeling? J Contemp Dent Pract 2016;17(4):270-274.

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