Two Fatal Cases of Ethylene Glycol Poisoning

1978 ◽  
Vol 18 (2) ◽  
pp. 102-107 ◽  
Author(s):  
D. A. L. Bowen ◽  
P.S. B. Minty ◽  
A. Sengupta
Keyword(s):  
Ethylene Glycol ◽  
Chromatographic Analysis ◽  
Gas Chromatographic Analysis ◽  
Ethylene Glycol Poisoning ◽  
Salient Features ◽  
Serum And Urine

Two cases of self poisoning by ethylene glycol are reported. The salient features of fatal acute ethylene glycol poisoning are mentioned with detailed histological and toxicological findings. Gas chromatographic analysis was used to determine ethylene glycol levels in serum and urine.

2,3-Butanediol in plasma from an alcoholic mistakenly identified as ethylene glycol by gas-chromatographic analysis

1991 ◽  
Vol 37 (8) ◽  
pp. 1453-1455 ◽  
Author(s):  
A W Jones ◽  
L Nilsson ◽  
S A Gladh ◽  
K Karlsson ◽  
J Beck-Friis
Keyword(s):  
Gas Chromatography ◽  
Ethylene Glycol ◽  
Chromatographic Analysis ◽  
Enzymatic Production ◽  
Low Concentrations ◽  
Elimination Half ◽  
Ethylene Glycol Poisoning ◽  
Incorrect Diagnosis ◽  
High Concentrations ◽  
Derivatives Of

Abstract 2,3-Butanediol was mistakenly identified as ethylene glycol in plasma specimens from two alcoholic patients. The cyclic phenylboronate ester derivatives of 2,3-butanediol and ethylene glycol had the same retention time when OV-17 was used as the stationary phase for gas chromatography. This led to incorrect diagnosis of ethylene glycol poisoning and unnecessary invasive therapy. Plasma from two chronic alcoholics contained 2,3-butanediol at 3.5 and 3.4 mmol/L. The elimination half-life of 2,3-butanediol was 3.9 days when ethanol was administered during therapy for suspected ethylene glycol poisoning. Low concentrations of 2,3-butanediol might be present in blood of chronic alcoholics as a result of a novel pathway of intermediary metabolism associated with some forms of alcoholism. However, a more likely explanation for fairly high concentrations of 2,3-butanediol is enzymatic production from 2-butanone. This ketone occurs in denatured alcohol preparations often consumed by alcoholics in Sweden.

The mechanism of formation of 2,7-dimethyl-2,6-octadiene in the synthesis of 3-methylene-7-methyl-1,6-octadiene

1983 ◽  
Vol 48 (7) ◽  
pp. 1864-1866
Author(s):  
Jan Bartoň ◽  
Ivan Kmínek
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
Alkali Metal ◽  
Chromatographic Analysis ◽  
Solid Phase ◽  
Reaction Pathway ◽  
Mechanism Of Formation ◽  
Gas Chromatographic Analysis ◽  
C Nmr ◽  
Visual Observations

2,7-Dimethyl-2,6-octadiene is formed in the catalytic solution for the dimerization of 2-methyl-1,3-butadiene to β-myrcene (3-methylene-7-methyl-1,6-octadiene), as revealed by mass spectrometry and 13C NMR spectroscopy. Visual observations together with the results of gas chromatographic analysis of the catalytic solution suggest that the formation of 2,7-dimethyl-2,6-octadiene is associated with the transition of the alkali metal (sodium) from the solid phase into the solution. A reaction pathway is suggested accounting for the formation of 2,7-dimethyl-2,6-octadiene in the system.

Gas chromatographic analysis of water phenolic pollutants using acid-washed graphitised carbon black

1981 ◽  
Vol 14 (2) ◽  
pp. 86-88 ◽  
Author(s):  
A. Di Corcia ◽  
R. Samperi ◽  
E. Sebastiani ◽  
C. Severini
Keyword(s):  
Carbon Black ◽  
Chromatographic Analysis ◽  
Gas Chromatographic Analysis ◽  
Phenolic Pollutants
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