Atypical clinical presentation of visceral leishmaniasis: a rare case without splenomegaly

2019 ◽  
Vol 49 (3) ◽  
pp. 233-234
Author(s):  
Mirella Alves Cunha ◽  
Amanda Ginani Antunes ◽  
Marcela Mara Eufrasio de Azevedo ◽  
James Farley Rafael Maciel ◽  
Henio Godeiro Lacerda
Keyword(s):  
Visceral Leishmaniasis ◽  
Rare Case ◽  
Endemic Area ◽  
Clinical Presentation ◽  
Clinical Manifestations ◽  
Atypical Clinical Presentation ◽  
Splenic Size

Clinical manifestations of visceral leishmaniasis (VL) usually include splenomegaly. We report a case of a woman from an endemic area with fever but normal splenic size. This is rare, especially in patients not immunocompromised.

Atypical Presentation of Congenital Yellow Nail Syndrome in a 2-Year-Old Female

2013 ◽  
Vol 17 (1) ◽  
pp. 66-68 ◽  
Author(s):  
Michael Cecchini ◽  
Joseph Doumit ◽  
Nordau Kanigsberg
Keyword(s):  
Rare Case ◽  
Pediatric Patients ◽  
Clinical Presentation ◽  
Positive Family History ◽  
Clinical Manifestations ◽  
Clinical Entity ◽  
Unknown Etiology ◽  
Close Monitoring ◽  
Yellow Nail Syndrome ◽  
Atypical Clinical Presentation

Background: Yellow nail syndrome (YNS) is a rare clinical entity of unknown etiology that is characterized by a triad of yellow nails, respiratory manifestations, and lymphedema. The condition appears in the mid- to later years of life and only rarely in childhood. We describe a rare case of YNS with an atypical clinical presentation consisting of only yellow and dystrophic nails in a 2- year-old female since birth. Objective: A case of congenital YNS with only dystrophic and yellow nails is reported. Methods and Results: A 2-year-old female presented with yellow nails since birth. There was no positive family history. Physical examination revealed 20 thickened, dystrophic, yellow nails with onycholysis. There was no evidence of respiratory manifestations or lymphedema. Conclusion: Although rare, YNS can present as a congenital clinical entity and persist after birth. Pediatric patients with YNS show different clinical manifestations than the classic adult patient. The presence of yellow and dystrophic nails in the absence of respiratory and lymphatic manifestations may be the only sign of pathology and warrants close monitoring as progression to more serious complications can occur.

scholarly journals Primary hydatid cyst of the psoas adherent to the aortoiliac axis: a real therapeutic challenge

2021 ◽  
Vol 7 (7) ◽  
pp. 363
Author(s):  
Anwar Rahali ◽  
Rahal Mssrouri ◽  
Marouane Baiss ◽  
Abderrahmane Mansouri ◽  
Hamid Mohamed ◽  
...  
Keyword(s):  
Literature Review ◽  
Hydatid Cyst ◽  
Rare Case ◽  
Essential Role ◽  
Histological Analysis ◽  
Clinical Presentation ◽  
Atypical Clinical Presentation ◽  
Residual Cavity ◽  
Primary Hydatid Cyst

<p class="abstract">Hydatidosis of the psoas is an unusual entity even in countries endemic to hydatid disease. We reported a rare case of hydatid cyst of psoas in a 54 year old man without pathological history. The atypical clinical presentation and the uncharacterizable radiology have demonstrated the essential role of surgery and histological analysis in the management of this type of lesion. The patient underwent a resection of the protruding dome with drainage of the residual cavity  because of the anatomical relationships of this hydatid cyst. Through this case and literature review, we aimed to discuss the diagnostic means, the natural course of the disease, the differential diagnoses as well as the therapeutic options for a hydatid cyst of the psoas.</p>

scholarly journals APPENDICEAL MUCOCOELE WITH PARTIAL NON ROTATION OF GUT – A RARE CASE REPORT

2020 ◽  
pp. 1-2
Author(s):  
Shirish Bhagvat ◽  
Nikhil Dhimole
Keyword(s):  
Abdominal Pain ◽  
Rare Case ◽  
Patient Management ◽  
Clinical Presentation ◽  
Delayed Diagnosis ◽  
Laparoscopic Approach ◽  
Intermittent Abdominal Pain ◽  
Atypical Clinical Presentation ◽  
Rare Case Report

Mucocoele of appendix and partial non-rotation of gut are rare pathological entities, and when they are present together they pose diagnostic and therapeutic difficulties due to atypical clinical presentation. This dilemma of varied clinical presentation can lead to delayed diagnosis and complications, thereby adversely affecting patient management and outcome. We report a 33 year old lady, presenting with intermittent abdominal pain in the periumbillical since 3 months diagnosed to have an appendiceal mucocoele with partial non rotation of gut on imaging. The patient underwent laparoscopic appendectomy and was discharged on post operative day 1 following an uneventful course with no recurrence on 6 months of follow up. Histopathology of the specimen confirmed the diagnosis of mucocoele of appendix with no evidence of malignancy. To our knowledge, this is the first reported case of mucocoele of appendix with partial non rotation of gut managed with minimally invasive laparoscopic approach.

scholarly journals An Intraarticular Osteoid Osteoma: A Case Report & Review of Literature

2014 ◽  
Vol 3 (2) ◽  
pp. 77-80
Author(s):  
AR Pant ◽  
MK Gupta ◽  
PK Santhalia ◽  
K Ahmad ◽  
RPS Kalawar ◽  
...  
Keyword(s):  
Shoulder Pain ◽  
Osteoid Osteoma ◽  
Rare Case ◽  
Clinical Presentation ◽  
Review Of Literature ◽  
Delay In Diagnosis ◽  
Atypical Clinical Presentation ◽  
The Common ◽  
Central Calcification ◽  
Chronic Shoulder Pain

 Osteoid osteoma (OO) is one of the common benign bone tumors but an uncommon cause of musculoskeletal pain. Its diagnosis is usually not difficult in classic clinical setup and in typical location in diaphyseal region. However, the diagnosis of juxta or intraarticular osteoid osteoma (IAOO) is challenging because of atypical clinical presentation responsible for delay in diagnosis and treatment. We report a rare case of IAOO as a cause of chronic shoulder pain to make clinician aware to help in its early diagnosis and management. A 28-year-old woman presented with chronic debilitating right shoulder pain. The diagnosis was established on CTscan after 2 years of onset of symptoms because of atypical clinical presentation as a chronic monoarthritis of the shoulder. CTscan demonstrated radiolucent nidus with central calcification with areas of surrounding sclerosis. The tumor was excised surgically and histopathologic examination confirmed the diagnosis of osteoid osteoma. So, in the scenario of an unexplained chronic monoarthritis, the possibility of intraarticular osteoid osteoma should also be kept in mind. CT-scan remains the investigation of choice for demonstrating the nidus and surgical exicision relieves the symptoms.  DOI: http://dx.doi.org/10.3126/njr.v3i2.9615   Nepalese Journal of Radiology Vol.3(2)July-Dec, 2013: 77-80

scholarly journals Assessment of histological liver alterations in dogs naturally infected with Leishmania infantum

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Isadora S. Lima ◽  
Manuela S. Solcá ◽  
Wagner L. Tafuri ◽  
Luiz A. R. de Freitas ◽  
Washington L. C. dos-Santos
Keyword(s):  
Visceral Leishmaniasis ◽  
Kupffer Cell ◽  
Endemic Area ◽  
Defense Mechanism ◽  
Natural Infection ◽  
Clinical Manifestations ◽  
Parasite Load ◽  
Inflammatory Cells ◽  
Cell Hypertrophy ◽  
Hematological And Biochemical Parameters

Abstract Background The liver plays a central role in the development of canine visceral leishmaniasis. Studies of natural infection in animals and humans indicate a direct relationship between resolution of infection and the formation and maturation of granulomas in the liver. However, in contrast to other reports in the literature, the present study found no differences in the characteristics of hepatic granulomas that could be related to resistance or susceptibility to Leishmania. Here, we describe the hepatic alterations observed in dogs with differing clinical manifestations of visceral leishmaniasis in an endemic area in the state of Bahia, Brazil. Methods We examined 148 animals in an endemic area. The animals were clinically examined, and the infection was determined by ELISA, spleen aspirate culture and quantitative PCR. The animals were grouped into asymptomatic or symptomatic based on the number of signs of LV. The histological liver evaluation was performed in a blinded way. Results Our results indicated no association between the characteristics of granulomas and clinical presentation. We found an association between the intensity of this inflammatory response and parasite load in the animals’ spleens. It is important to note that while hepatic alterations, such as portal and perivascular inflammation and the presence of larger amounts of granulomas, were linked with higher parasite loads, we found the inverse to be true with respect to intrasinusoidal lymphocytosis, the formation of intrasinusoidal inflammatory cell aggregates and Kupffer cell hypertrophy. Conclusions Our findings suggest that the presence of mononuclear inflammatory cells inside the sinusoids is more important than that of organized granulomas in terms of the containment of parasitism by the host. We suggest that the presence of granulomas indicates the failure of a first line of defense mechanism in the control of parasite infection, which could be related to the presence of inflammatory cells and Kupffer cell hypertrophy inside the sinusoids. We further demonstrated that dogs with active Leishmania spp. infection present a higher frequency of inflammatory changes in the liver. In addition to being correlated with the severity of clinical manifestation, these hepatic alterations were also associated with changes in hematological and biochemical parameters.

Frontal Linear Scleroderma (en coup de sabre): A Case Report

2021 ◽  
pp. 105566562110131
Author(s):  
Yo Han Oh ◽  
Soo Hyang Lee
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Clinical Presentation ◽  
Disease Onset ◽  
Clinical Manifestations ◽  
Localized Scleroderma ◽  
Radiological Findings ◽  
Laboratory Results ◽  
Unusual Variant ◽  
Over Time

En coup de sabre is an unusual variant of localized scleroderma characterized by its distinct location involving the frontoparietal region of the forehead and scalp. The authors describe a rare case of en coup de sabre in a 3-year-old boy whose disease onset was at 12 months of age. This article presents the clinical manifestations of continuous changes in the lesion photographed over time. The clinical presentation, laboratory results, and radiological findings together with a brief discussion of the management of the disease are discussed.

scholarly journals Rare Oral Mucous Extravasation Cyst: Case Report

2021 ◽  
Vol 6 (04) ◽  
pp. 275-278
Author(s):  
Rajae El Gaouzi ◽  
Bassima Chami
Keyword(s):  
Rare Case ◽  
Clinical Characteristics ◽  
Hard Palate ◽  
Clinical Presentation ◽  
Minor Salivary Glands ◽  
Benign Lesions ◽  
Lower Lip ◽  
Histological Features ◽  
Floor Of Mouth ◽  
Atypical Clinical Presentation

Mucoceles are a benign lesions characterized by an extravasation or retention of mucous in submucosal tissue from minor salivary glands caused most probably by a trauma or habit of lip biting. They usually present as an asymptomatic small superficial swelling, which are knew to occur most commonly on the lower lip, followed by the floor of mouth and in other sites. However, uncommon variants of oral mucoceles sometimes occur. Such lesions may be difficult to diagnose due to their unusual localization and atypical clinical presentation. This paper highlights a rare case of mucocele localized in hard palate in a 63 years old male patient. The lesion was depressed, with a bluish appearance, and it measured 7 mm × 5 mm x 2 mm. Diagnosis is based on clinical characteristics, and confirmed with histological features.

scholarly journals CONGENITAL CARDITIS IN A NEWBORN (case report)

2019 ◽  
Vol 6 (1) ◽  
pp. 24-31
Author(s):  
M.O. Gonchar ◽  
A.V. Senatorova ◽  
N.K. Matsievskaya ◽  
D.V. Zatoloka
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Infectious Diseases ◽  
Diagnostic Criteria ◽  
Clinical Presentation ◽  
Clinical Manifestations ◽  
Intrauterine Infection ◽  
High Technology ◽  
Technology Research ◽  
Atypical Clinical Presentation

CONGENITAL CARDITIS IN A NEWBORN (case report)Gonchar M.O., Senatorova A.V., Matsiyevskaya N.K., Zatoloka D.V.Diagnosis of carditis in newborns presents a number of difficulties, even with the results of high-technology research methods. Carditis is characterized by the absence of specific diagnostic criteria, similarity of clinical manifestations of cardiovascular and respiratory failure in young children, including secondary to generalized infectious diseases. The article presents a case of an atypical clinical presentation of carditis in a child with a confirmed intrauterine infection.Key words: newborns, carditis, intrauterine infection ВРОДЖЕНИЙ КАРДИТ У НОВОНАРОДЖЕНОГО (клінічне спостереження)Гончар М.О., Сенаторова А.В., Мацієвська Н.К., Затолока Д.В.Встановлення діагнозу кардит у новонароджених має ряд труднощів, навіть при наявності результатів високотехнологічних методів дослідження. Кардит характеризується відсутністю специфічних діагностичних критеріїв, схожістю клінічних проявів серцево-судинної і дихальної недостатності у дітей раннього віку, в тому числі на тлі генералізованої інфекційної патології. У статті представлений випадок нетипового клінічного перебігу розвитку кардиту у дитини з підтвердженою внутрішньоутробною інфекцією.Ключові слова: новонароджені, кардит, внутрішньоутробна інфекція ВРОЖДЕННЫЙ КАРДИТ У НОВОРОЖДЕННОГО (клиническое наблюдение)Гончарь М.О., Сенаторова А.В., Мациевская Н.К., Затолока Д.В.Установление диагноза кардит у новорождённых имеет ряд сложностей, даже при наличие  результатов высокотехнологических методов исследования. Кардит характеризуется отсутствием специфических диагностических критериев, сходством клинических проявлений сердечно-сосудистой и дыхательной недостаточности у детей раннего возраста, в том числе на фоне генерализованной инфекционной патологии. В статье представлен случай нетипичного клинического течения развития кардита у ребенка с подтвержденной внутриутробной инфекцией.Ключевые слова: новорожденные, кардит, внутриутробная инфекция  

scholarly journals Isolated liver tuberculosis

2016 ◽  
Vol 7 (1) ◽  
pp. 71
Author(s):  
Ruksana Karim ◽  
Md. Mohsen Chowdhury ◽  
Arif Salam Khan
Keyword(s):  
Preoperative Diagnosis ◽  
Rare Case ◽  
Clinical Presentation ◽  
Rare Condition ◽  
Metastatic Carcinoma ◽  
Correct Preoperative Diagnosis ◽  
Hepatic Tuberculosis ◽  
Atypical Clinical Presentation ◽  
Isolated Liver ◽  
Space Occupying Lesion

Isolated liver tuberculosis is still considered a rare condition and its atypical clinical presentation challenges the clinical acumen of the treating physician. There is difficulty in reaching the correct preoperative diagnosis of nodular hepatic tuberculosis that presents as a space-occupying lesion. It is usually unsuspected and confused with primary or metastatic carcinoma of the liver. In this report, we describe a rare case of isolated liver tuberculosis.

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