Evaluation and Critical Appraisal of a Random Sample of Drug Information Practice In United States Academic and Industry Medical Information Centers

2000 ◽  
Vol 34 (4) ◽  
pp. 1133-1138 ◽  
Author(s):  
Meghan E. Shannon ◽  
Susan E. Malecha ◽  
Amy J. Cha ◽  
Mary Lynn Moody
2019 ◽  
Vol 27 (3) ◽  
pp. 449-456
Author(s):  
James R Rogers ◽  
Hollis Mills ◽  
Lisa V Grossman ◽  
Andrew Goldstein ◽  
Chunhua Weng

Abstract Scientific commentaries are expected to play an important role in evidence appraisal, but it is unknown whether this expectation has been fulfilled. This study aims to better understand the role of scientific commentary in evidence appraisal. We queried PubMed for all clinical research articles with accompanying comments and extracted corresponding metadata. Five percent of clinical research studies (N = 130 629) received postpublication comments (N = 171 556), resulting in 178 882 comment–article pairings, with 90% published in the same journal. We obtained 5197 full-text comments for topic modeling and exploratory sentiment analysis. Topics were generally disease specific with only a few topics relevant to the appraisal of studies, which were highly prevalent in letters. Of a random sample of 518 full-text comments, 67% had a supportive tone. Based on our results, published commentary, with the exception of letters, most often highlight or endorse previous publications rather than serve as a prominent mechanism for critical appraisal.


2019 ◽  
Vol 53 (4) ◽  
pp. 446-454 ◽  
Author(s):  
Jimmy Gonzalez ◽  
Samantha Bryant ◽  
Michael Hogan ◽  
Sandra Bai ◽  
Lesley Fierro ◽  
...  

1976 ◽  
Vol 6 (1) ◽  
pp. 50-55
Author(s):  
Arthur Ruskin

Arguing that the scientific method must be the ultimate test in determining drug efficacy and safety, Dr. Ruskin points out that the medical profession is often plagued by unscientific attitudes and “research.” Like their patients, physicians are influenced by nonscientific sources of drug information such as advertising and often trust their own “experience” rather than the results of controlled clinical and epidemiologic trials.


Author(s):  
Barbara Barksdale Clowse

Directing Sheppard-Towner programs in Arkansas plunged Bradley into a political imbroglio and forced her resignation. She authored a set of booklets describing healthcare issues of a fictional couple. Praise for this method of disseminating accurate medical information came from all over the United States and Canada. In 1923 she delivered four lectures to the new American Child Health Association.


1991 ◽  
Vol 9 (7) ◽  
pp. 1314-1319 ◽  
Author(s):  
R E Doblin ◽  
M A Kleiman

A random-sample, anonymous survey of the members of the American Society of Clinical Oncology (ASCO) was conducted in spring 1990 measuring the attitudes and experiences of American oncologists concerning the antiemetic use of marijuana in cancer chemotherapy patients. The survey was mailed to about one third (N = 2,430) of all United States-based ASCO members and yielded a response rate of 43% (1,035). More than 44% of the respondents report recommending the (illegal) use of marijuana for the control of emesis to at least one cancer chemotherapy patient. Almost one half (48%) would prescribe marijuana to some of their patients if it were legal. As a group, respondents considered smoked marijuana to be somewhat more effective than the legally available oral synthetic dronabinol ([THC] Marinol; Unimed, Somerville, NJ) and roughly as safe. Of the respondents who expressed an opinion, a majority (54%) thought marijuana should be available by prescription. These results bear on the question of whether marijuana has a "currently accepted medical use," at issue in an ongoing administrative and legal dispute concerning whether marijuana in smoked form should be available by prescription along with synthetic THC in oral form. This survey demonstrates that oncologists' experience with the medical use of marijuana is more extensive, and their opinions of it are more favorable, than the regulatory authorities appear to have believed.


1988 ◽  
Vol 24 (1-4) ◽  
pp. 307-311 ◽  
Author(s):  
M. Ronca-Battista ◽  
M. Moon ◽  
J. Bergsten ◽  
S.B. White ◽  
B. Alexander ◽  
...  

Abstract During the winter of 1986-1987, the United States Environmental Protection Agency (EPA) provided assistance to ten states to begin state-wide radon surveys. This paper presents survey results from the five states that completed a survey using a probability sample of housing units. Radon concentrations in six thousand homes in Alabama, Kentucky, Tennessee, Wisconsin, and Wyoming were measured. The data recorded from detectors placed in those houses have been compiled into the first multi-state survey of radon levels that allows valid extrapolation to the population at large. The target population was ground level, owner occupied residences with listed telephone numbers. Each state was partitioned into strata according to geologic characteristics relevant to radon levels. A systematic random sample of telephone numbers was selected within each stratum, and the telephone numbers together with associated names and addresses were supplied to each state. Charcoal canisters were deployed for a two-day period in each sample home, following the EPA screening measurement protocol. Strict procedures were followed to ensure randomness of the sample and the accuracy of the measurements. The results were analysed to produce estimates of the frequency distribution of radon concentrations throughout each state and for areas within states. A smaller sample of residences which were volunteered by their owners in each state also received detectors. The radon data from these houses were analysed separately. Estimates from the two northern states were significantly higher than those from the more southerly states and estimates for volunteers tended to be higher than the estimates from the random sample of homes. In the former case, the differences were influenced by the proportion of homes with basements.


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