Effectiveness of a Family-based Diabetes Self-management Educational Intervention for Chinese Adults With Type 2 Diabetes in Wuhan, China

2016 ◽  
Vol 42 (6) ◽  
pp. 697-711 ◽  
Author(s):  
Chun Cai ◽  
Jie Hu
Keyword(s):  
Educational Intervention ◽  
Repeated Measures ◽  
Intervention Group ◽  
Self Management ◽  
Control Group ◽  
Related Quality ◽  
Health Related ◽  
Family Based

Purpose The purpose of the study was to examine the effects of a family-based self-management educational intervention on self-management in adults with type 2 diabetes mellitus (T2DM) in Wuhan, China. Methods A quasi-experimental design with repeated measures was employed. Chinese patients with T2DM (N = 57) and their family members were assigned to 2 groups. The intervention group (n1 = 29) received a tailored 7-session educational intervention and the control group (n2 = 28) received routine care in the community. Data were collected at pre- and postintervention and at the end of the 3-month follow-up. Descriptive analysis and repeated-measures analysis of variance were used to analyze the data. Results Participants with T2DM in the intervention group showed significance in greater reductions in A1C, body mass index, and waist circumference and significant improvements in diabetes knowledge, diabetes self-efficacy, self-care activities, and health-related quality of life compared with those in the control group. Family members in the intervention group had significant improvements in diabetes knowledge and health-related quality of life. Conclusion Study findings demonstrated that a family-based diabetes self-management intervention incorporating self-efficacy theory may help Chinese adults with T2DM in modifying their lifestyle and performing self-care activities to improve A1C management.

scholarly journals Feasibility Trial of an eHealth Intervention for Health-Related Quality of Life: Implications for Managing Patients with Chronic Pain During the COVID-19 Pandemic

Healthcare ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 381
Author(s):  
John C. Licciardone ◽  
Vishruti Pandya
Keyword(s):  
Treatment Group ◽  
Self Management ◽  
Control Group ◽  
Low Back ◽  
Wait List Control ◽  
Cluster Score ◽  
Related Quality ◽  
Health Related ◽  
Ehealth Intervention

Purpose: This study was conducted to determine the feasibility of providing an eHealth intervention for health-related quality of life (HRQOL) to facilitate patient self-management. Methods: A randomized controlled trial was conducted from 2019–2020 within the Pain Registry for Epidemiological, Clinical, and Interventional Studies and Innovation. Eligible patients included those with chronic low back pain and a SPADE (sleep disturbance, pain interference with activities, anxiety, depression, and low energy/fatigue) cluster score ≥ 55 based on the relevant scales from the Patient-Reported Outcomes Measurement Information System instrument with 29 items (PROMIS-29). Patients were randomized to the eHealth treatment group, which received a tailored HRQOL report and interpretation guide, or to a wait-list control group. The primary outcome was change in the SPADE cluster score, including its five component scales, over 3 months. Secondary outcomes were changes in low back pain intensity and back-related disability. Treatment effects were measured using the standardized mean difference (SMD) in change scores between groups. The eHealth intervention was also assessed by a survey of the experimental treatment group 1 month following randomization. Results: A total of 102 patients were randomized, including 52 in the eHealth treatment group and 50 in the wait-list control group, and 100 (98%) completed the trial. A majority of patients agreed that the HRQOL report was easy to understand (86%), provided new information (79%), and took actions to read or learn more about self-management approaches to improve their HRQOL (77%). Although the eHealth intervention met the criteria for a small treatment effect in improving the overall SPADE cluster score (SMD = 0.24; p= 0.23) and anxiety (SMD = 0.24; p = 0.23), and for a small-to-medium treatment effect in improving depression (SMD = 0.37; p = 0.06) and back-related disability (SMD = 0.36; p = 0.07), none of these results achieved statistical significance because of limited sample size. Conclusion: Given the feasibility of rapid online deployment, low cost, and low risk of adverse events, this eHealth intervention for HRQOL may be useful for patients with chronic pain during the COVID-19 pandemic.

Effects of a nine-month occupational intervention on health-related quality of life

2017 ◽  
Vol 45 (4) ◽  
pp. 452-458
Author(s):  
Birgitta Ojala ◽  
Clas-Håkan Nygård ◽  
Heini Huhtala ◽  
Seppo T. Nikkari
Keyword(s):  
Quality Of Life ◽  
Intervention Group ◽  
Cognitive Behavioral ◽  
Control Group ◽  
Base Line ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

The aim of this study was to evaluate the effectiveness of vocationally outpatient oriented rehabilitation on an intervention group, compared with a control group that did not take part in the intervention. The groups were compared for health-related quality of life (HRQoL) by the quantitative indicator RAND 36. Data were obtained by a self-report at baseline and at nine months follow-up. Differences between base-line and follow-up were analyzed within group and between the groups. The study population consisted of 751 municipal employees aged between 26 and 64 years; an intervention with 463 women and 115 men ( n = 578), and a control group with 138 women and 35 men ( n = 173). In this study we focused on those who had answered to all questions in RAND 36, thus 581 remained. Of these, 388 were in the intervention group (mean age 49.0 years) and 110 in the control group (mean age 48.4 years). Intervention was based on cognitive behavioral therapy. Participants in the 9-month outpatient intervention group showed statistically significant increase in all eight RAND 36 areas. Most improvement was seen in the psychosocial functioning index ( p = 0.002). Although there were no statistically significant changes in RAND 36 components in the control group, difference in changes between groups were seen in energy and fatigue ( p < 0.001), social functioning ( p = 0.032) and general health perceptions 0.027 in favor of the intervention group. The results suggest that a cognitive behavioral intervention as an early rehabilitation program is effective in increasing employees’ quality of life, as measured by RAND 36.

scholarly journals Effects of WeChat-based Educational Intervention on Depression and Quality of Life in Patients with Ankylosing Spondylitis: A Randomized Controlled Trail

2021 ◽  
Author(s):  
Yuqing Song ◽  
Xia Xie ◽  
Yanlin Chen ◽  
Ying Wang ◽  
Hui Yang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Ankylosing Spondylitis ◽  
Educational Intervention ◽  
Intervention Group ◽  
Control Group ◽  
Positive Effects ◽  
Randomized Controlled ◽  
Health Related Qol ◽  
Health Related

Abstract Background: Ankylosing spondylitis(AS), as a common inflammatory rheumatic disease, often cause depression and impaired health-related quality of life(QoL). Although positive effects of patient education have been demonstrated, limited studies explored the benefits of education via mobile applications for AS patients. This study aimed to evaluate the effects of the WeChat-based educational intervention on depression and health-related QoL in AS patients.Methods: We conducted a single-blind randomized controlled trial from March to December 2017. Potential patients were recruited and randomized into the intervention group who received a 12-week WeChat-based educational intervention (consisting of four individual online educational sessions, online health information) or the control group receiving standard care. Data was collected at baseline and 12 weeks after the intervention. Outcomes were measured by Beck Depression Inventory-Ⅱ, the Medical Outcomes Study Short Form 36-item Health Survey, Bath Ankylosing Spondylitis Patient Global Score, visual analogue scales. Results: A total of 118 patients with AS were included and analysed. Measures at baseline were comparable between groups. After the intervention, the intervention group reported significant higher scores of all dimensions of QoL except for physical function and validity, compared with the control group. Additionally, patients in the intervention group had lower depressive symptom than the control group. No significant difference in other outcomes was observed at 12 weeks. Conclusions: This study found that the 12-week educational intervention via WeChat had positive effects on reducing depressive symptom and improving health related QoL in Chinese patients with AS. We suggest that this intervention can be integrated into current routine care of AS patients. Trial registration: Chinese Clinical Trail Registry (registry number: ChiCTR-IPR-16009293). Registered September 29, 2016.

scholarly journals Health-Related Quality of Life Improvements in Systemic Lupus Erythematosus Derived from a Digital Therapeutic Plus Tele-Health Coaching Intervention: Randomized Controlled Pilot Trial (Preprint)

2020 ◽  
Author(s):  
Faiz Khan ◽  
Nora Granville ◽  
Raja Malkani ◽  
Yash Chathampally
Keyword(s):  
Quality Of Life ◽  
Usual Care ◽  
Lupus Erythematosus ◽  
Therapeutic Intervention ◽  
Intervention Group ◽  
Control Group ◽  
Randomized Controlled ◽  
Related Quality ◽  
Health Related

BACKGROUND Systemic lupus erythematosus (SLE), a systemic autoimmune disease with no known cure, remains poorly understood and patients suffer from many gaps in care. Recent work has suggested that dietary and other lifestyle factors play an important role in triggering and propagating SLE in some susceptible individuals. However, the magnitude of influence of these triggers, how to identify pertinent triggers in individual patients, and whether removing these triggers confers clinical benefit is unknown. OBJECTIVE To demonstrate that a digital therapeutic intervention, utilizing a mobile app that allows self-tracking of dietary, environmental, and lifestyle triggers, paired with telehealth coaching, added to usual care, improves quality of life in patients with SLE compared with usual care alone. METHODS In this randomized controlled pilot study, adults with SLE were assigned to a 16-week digital therapeutic intervention plus usual care or usual care alone. Primary outcome measures were changes from baseline to 16 weeks on 3 validated health-related quality of life (HRQoL) tools: Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), Brief Pain Inventory-Short Form (BPI-SF), and Lupus Quality of Life (LupusQoL). RESULTS A total of 50 patients were randomized (23 control, 27 intervention). In per-protocol analysis, the intervention group achieved significantly greater improvement than the control group in 9 of 11 domains: FACIT-F (34% absolute improvement for the intervention group vs –1% for the control group, <i>P</i>&lt;.001), BPI-SF-Pain Interference (25% vs 0%, <i>P</i>=.02), LupusQoL-Planning (17% vs 0%, <i>P</i>=.004), LupusQoL-Pain (13% vs 0%, <i>P</i>=.004), LupusQoL-Emotional Health (21% vs 4%, <i>P</i>=.02), and LupusQoL-Fatigue (38% vs 13%, <i>P</i>&lt;.001) were significant when controlling for multiple comparisons; BPI-SF-Pain Severity (13% vs –6%, <i>P</i>=.049), LupusQoL-Physical Health (17% vs 3%, <i>P</i>=.049), and LupusQoL-Burden to Others (33% vs 4%, <i>P</i>=.04) were significant at an unadjusted 5% significance level. CONCLUSIONS A digital therapeutic intervention that pairs self-tracking with telehealth coaching to identify and remove dietary, environmental, and lifestyle symptom triggers resulted in statistically significant, clinically meaningful improvements in HRQoL when added to usual care in patients with SLE. CLINICALTRIAL ClinicalTrials.gov NCT03426384; https://clinicaltrials.gov/ct2/show/NCT03426384

Does screening for adverse effects improve health outcomes in epilepsy?

Neurology ◽  
2020 ◽  
Vol 95 (3) ◽  
pp. e239-e246 ◽  
Author(s):  
Valentina Franco ◽  
Maria Paola Canevini ◽  
Giovambattista De Sarro ◽  
Cinzia Fattore ◽  
Guido Fedele ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Adverse Effects ◽  
Intervention Group ◽  
Final Visit ◽  
Control Group ◽  
Systematic Screening ◽  
Related Quality ◽  
High Adverse Event ◽  
Health Related

ObjectiveTo determine whether systematic screening for adverse effects of antiepileptic drugs (AEDs) reduces toxicity burden and improves health-related quality of life in patients with epilepsy.MethodsConsecutive patients with uncontrolled seizures aged ≥16 years and a high Adverse Event Profile (AEP) score were randomized to 2 groups and followed up for 18 months at 11 referral centers. AEP scores were made available to treating physicians at all visits in the intervention group, but not in the control group. Co–primary endpoints were changes in AEP scores and Quality of Life Inventory for Epilepsy-31 (QOLIE–31) scores.ResultsOf 809 enrolled patients able to complete the AEP questionnaire, 222 had AEP scores ≥45 and were randomized to the intervention (n = 111) or control group (n = 111). A total of 206 patients completed the 18-month follow-up. Compared with baseline, AEP scores decreased on average by 7.2% at 6 months, 12.1% at 12 months, and 13.8% at 18 months in the intervention group (p < 0.0001), and by 7.7% at 6 months, 9.2% at 12 months, and 12.0% at 18 months in controls (p < 0.0001). QOLIE-31 scores also improved from baseline to final visit, with a mean 20.7% increase in the intervention group and a mean 24.9% increase in the control group (p < 0.0001). However, there were no statistically significant differences in outcomes between groups for the 2 co–primary variables.ConclusionsContrary to findings from a previous study, systematic screening for adverse effects of AEDs using AEP scores did not lead to a reduced burden of toxicity over usual physician treatment.Italian Medicines Agency (AIFA) identifierFARM52K2WM_003.Clinicaltrials.gov identifierNCT03939507 (registered retrospectively in 2019; the study was conducted during the 2006–2009 period and registration of clinical trials was not a widely established practice when this study was initiated).Classification of evidenceThis study provides Class II evidence that the additional collection of formal questionnaires regarding adverse effects of AEDs does not reduce toxicity burden over usual physician treatment.

scholarly journals A Web-Based Self-Titration Program to Control Blood Pressure in Patients With Primary Hypertension: Randomized Controlled Trial (Preprint)

2019 ◽  
Author(s):  
Chi-Wen Kao ◽  
Ting-Yu Chen ◽  
Shu-Meng Cheng ◽  
Wei-Shiang Lin ◽  
Yue-Cune Chang
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Intervention Group ◽  
Primary Hypertension ◽  
Control Group ◽  
Health Related Quality ◽  
Web Based ◽  
Related Quality ◽  
Health Related

BACKGROUND Hypertension is a major cause of mortality in cardiac, vascular, and renal disease. Effective control of elevated blood pressure has been shown to reduce target organ damage. A Web-based self-titration program may empower patients to control their own disease, share decisions about antihypertensive dose titration, and improve self-management, ultimately improving health-related quality of life. OBJECTIVE Our primary aim was to evaluate the effects of a Web-based self-titration program for improving blood pressure control in patients with primary hypertension. Our secondary aim was to evaluate the effects of that program on improving health-related quality of life. METHODS This was a parallel-group, double-blind, randomized controlled trial with assessments at baseline, 3 months, and 6 months. We included patients with primary hypertension (blood pressure&gt;130/80 mm Hg) from a cardiology outpatient department in northern Taiwan and divided them randomly into intervention and control groups. The intervention group received the Web-based self-titration program, while the control group received usual care. The random allocation was concealed from participants and outcome evaluators. Health-related quality of life was measured by the EuroQol five-dimension self-report questionnaire. We used generalized estimating equations to evaluate the effects of the intervention. RESULTS We included 222 patients and divided them equally into intervention (n=111) and control (n=111) groups. Patients receiving the Web-based self-titration program showed significantly greater improvement in the systolic and diastolic blood pressure control than those who did not receive this program, at 3 months (–21.4 mm Hg and –5.4 mm Hg, respectively; <italic>P</italic>&lt;.001) and 6 months (–27.8 mm Hg and –9.7 mm Hg, respectively; <italic>P</italic>&lt;.001). Compared with the control group, the intervention group showed a significant decrease in the overall defined daily dose at both 3 (–0.202, <italic>P</italic>=.003) and 6 (–0.236, <italic>P</italic>=.001) months. Finally, health-related quality of life improved significantly in the intervention group compared with the control group at both 3 and 6 months (both, <italic>P</italic>&lt;.001). CONCLUSIONS A Web-based self-titration program can provide immediate feedback to patients about how to control their blood pressure and manage their disease at home. This program not only decreases mean blood pressure but also increases health-related quality of life in patients with primary hypertension. CLINICALTRIAL ClinicalTrials.gov NCT03470974; https://clinicaltrials.gov/ct2/show/NCT03470974

The Effectiveness of EMLA as a Primary Dressing on Painful Chronic Leg Ulcers: Effects on Wound Healing and Health-Related Quality of Life

2017 ◽  
Vol 16 (3) ◽  
pp. 163-172 ◽  
Author(s):  
Anne Purcell ◽  
Thomas Buckley ◽  
Judith Fethney ◽  
Jennie King ◽  
Wendy Moyle ◽  
...  
Keyword(s):  
Wound Healing ◽  
Intervention Group ◽  
Control Group ◽  
Leg Ulcers ◽  
Health Related Quality ◽  
Intervention Period ◽  
Related Quality ◽  
Health Related ◽  
Chronic Leg Ulcers

This study aimed to evaluate the effect of EMLA 5% cream applied to painful chronic leg ulcers (CLUs) as a primary dressing on wound healing and health-related quality of life (HRQoL). A pilot, parallel-group, nonblinded, randomized controlled trial was conducted in 6 community nursing procedure clinics in New South Wales, Australia. A total of 60 participants with painful CLUs of varied etiology were randomly assigned to the intervention (EMLA daily for 4 weeks as a primary dressing, followed by usual care) or usual care only. Wound size and HRQoL were measured at baseline, end of the intervention period (week 4), and week 12. At baseline, wound sizes were similar for both the intervention and control groups. During the intervention period, there was no significant difference in wound sizes between groups (intervention group: median (cm2) = 2.4, IQR = 1.3-12.7; control group: median (cm2) = 5.0, IQR = 2.5-9.9; P = .05). Mean HRQoL scores for all subscales at baseline and weeks 4 and 12 were similar between groups except for Wellbeing, which was significantly higher in the intervention group at the end of the 4-week intervention period (intervention group: mean = 52.41, SD = 24.50; control group: mean = 38.15, SD = 21.25; P = .03; d = 0.62). The trial findings suggest that daily applications of EMLA as a primary dressing do not inhibit wound healing and may improve patient well-being. Studies with larger samples are required to more comprehensively evaluate the impact of this treatment on wound healing and HRQoL.

scholarly journals Improvements in health-related quality of life and function in middle-aged women with chronic diseases of lifestyle after participating in a non-pharmacological intervention programme: A pragmatic randomised controlled trial

2019 ◽  
Vol 8 ◽  
Author(s):  
Roline Y. Barnes ◽  
Jennifer Jelsma ◽  
Romy Parker
Keyword(s):  
Quality Of Life ◽  
Chronic Diseases ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Randomised Controlled

Background: Musculoskeletal diseases consume a large amount of health and social resources and are a major cause of disability in both low- and high-income countries. In addition, patients frequently present with co-morbid chronic diseases of lifestyle. The area of musculoskeletal disease is restricted by a lack of epidemiological knowledge, particularly in low- and middle-income countries.Objectives: This pragmatic randomised controlled trial assessed the benefits of a 6-week physiotherapy intervention for middle-aged women with musculoskeletal conditions compared to usual care.Method: A weekly 2-h educational programme utilising a workbook, discussion group and exercise class was presented for the intervention group, while the control group received usual care. The primary outcome was health-related quality of life. Parametric and non-parametric data were used to determine the equivalence between the groups.Results: Twenty-two participants were randomised to the intervention and 20 to the control group. The control group demonstrated no within-group improvement in health-related quality of life items, compared to significant improvements in two items in the intervention group. The change in median utility score within the intervention group was twice as large as the change in the control group. With regard to self-efficacy, the intervention group demonstrated significant within-group changes in perceived management of fatigue and discomfort.Conclusion: The positive impact of the intervention on the participants suggests that the programme should continue at the clinic in question, but should be presented at a more convenient time for participants who work, as recruitment to the study was less than anticipated. Primary health care systems in South Africa urgently need to put structures in place for effective management of the functional impact of chronic diseases of lifestyle and musculoskeletal conditions. It is time for physiotherapists and possibly other health care professionals to participate in the development of appropriate community level interventions to address the functioning and quality of life of individuals living with the diseases.

scholarly journals A Web-Based Self-Titration Program to Control Blood Pressure in Patients With Primary Hypertension: Randomized Controlled Trial

10.2196/15836 ◽  
2019 ◽  
Vol 21 (12) ◽  
pp. e15836 ◽  
Author(s):  
Chi-Wen Kao ◽  
Ting-Yu Chen ◽  
Shu-Meng Cheng ◽  
Wei-Shiang Lin ◽  
Yue-Cune Chang
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Intervention Group ◽  
Primary Hypertension ◽  
Control Group ◽  
Health Related Quality ◽  
Web Based ◽  
Related Quality ◽  
Health Related

Background Hypertension is a major cause of mortality in cardiac, vascular, and renal disease. Effective control of elevated blood pressure has been shown to reduce target organ damage. A Web-based self-titration program may empower patients to control their own disease, share decisions about antihypertensive dose titration, and improve self-management, ultimately improving health-related quality of life. Objective Our primary aim was to evaluate the effects of a Web-based self-titration program for improving blood pressure control in patients with primary hypertension. Our secondary aim was to evaluate the effects of that program on improving health-related quality of life. Methods This was a parallel-group, double-blind, randomized controlled trial with assessments at baseline, 3 months, and 6 months. We included patients with primary hypertension (blood pressure>130/80 mm Hg) from a cardiology outpatient department in northern Taiwan and divided them randomly into intervention and control groups. The intervention group received the Web-based self-titration program, while the control group received usual care. The random allocation was concealed from participants and outcome evaluators. Health-related quality of life was measured by the EuroQol five-dimension self-report questionnaire. We used generalized estimating equations to evaluate the effects of the intervention. Results We included 222 patients and divided them equally into intervention (n=111) and control (n=111) groups. Patients receiving the Web-based self-titration program showed significantly greater improvement in the systolic and diastolic blood pressure control than those who did not receive this program, at 3 months (–21.4 mm Hg and –5.4 mm Hg, respectively; P<.001) and 6 months (–27.8 mm Hg and –9.7 mm Hg, respectively; P<.001). Compared with the control group, the intervention group showed a significant decrease in the overall defined daily dose at both 3 (–0.202, P=.003) and 6 (–0.236, P=.001) months. Finally, health-related quality of life improved significantly in the intervention group compared with the control group at both 3 and 6 months (both, P<.001). Conclusions A Web-based self-titration program can provide immediate feedback to patients about how to control their blood pressure and manage their disease at home. This program not only decreases mean blood pressure but also increases health-related quality of life in patients with primary hypertension. Trial Registration ClinicalTrials.gov NCT03470974; https://clinicaltrials.gov/ct2/show/NCT03470974

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