Resection of primary malignant lung melanoma: a case report

2018 ◽  
Vol 26 (9) ◽  
pp. 710-712 ◽  
Author(s):  
Hiroshi Yabuki ◽  
Kenta Kuwana ◽  
Muneo Minowa
Keyword(s):  
Malignant Melanoma ◽  
Lower Lobe ◽  
Pathological Examination ◽  
High Grade Fever ◽  
Lung Lobe ◽  
Segmental Bronchus ◽  
Lower Lung ◽  
Bronchoscopic Biopsy ◽  
Lateral Posterior ◽  
The Right

A 74-year-old man presented with chest pain and high-grade fever. Chest radiography revealed a consolidation in the right lower lung lobe, and computed tomography demonstrated atelectasis and infiltration of the right lower lobe, with pleural effusion. Bronchoscopy revealed a tumor occluding the inlet of the lateral/posterior basal segmental bronchus of the right lung, but bronchoscopic biopsy did not lead to a definitive diagnosis. Considering the possibility of obstructive pneumonia and pleuritis, we performed a right lower lobectomy, decortication, and pleuroclysis. Pathological examination revealed a malignant melanoma. The clinical and pathological findings suggested primary malignant melanoma of the lung.

scholarly journals Behçet's disease presenting with massive hemoptysis related to bronchovascular fistula: A case report

2021 ◽  
Vol 29 (3) ◽  
pp. 408-411
Author(s):  
Mehmet Ali Bedirhan ◽  
Naciye Arda ◽  
Elif Tanrıverdi ◽  
Volkan Yaran ◽  
Deniz Sansar ◽  
...  
Keyword(s):  
Lower Lobe ◽  
Lateral Wall ◽  
Punch Biopsy ◽  
Massive Bleeding ◽  
Pathological Examination ◽  
Massive Hemoptysis ◽  
High Dose ◽  
Thoracic Computed Tomography ◽  
Cyclophosphamide Treatment ◽  
The Right

A 37-year-old male patient was admitted to our hospital with recurrent hemoptysis, 50 mL per day. Thoracic computed tomography showed no pathology responsible for hemoptysis. Bronchoscopy revealed mucosal infiltrations and 2 to 3-mm blotch in the lateral wall of the right lower lobe. After punch biopsy of the suspected area, massive bleeding occurred. Right lower bilobectomy was performed urgently. A bronchovascular fistula was noticed at the specimen. Pathological examination result was compatible with clinically suspected Behçet"s disease. The patient was given high-dose steroid and cyclophosphamide treatment and received azathioprine maintenance treatment for 18 months. He has been symptom-free for three-year follow-up.

scholarly journals Gangrenous ischaemic colitis following lung wedge resection

2019 ◽  
Vol 12 (5) ◽  
pp. e227908 ◽  
Author(s):  
Kazuki Hayashi ◽  
Yasuhiko Ohshio ◽  
Jun Hanaoka
Keyword(s):  
Mesenteric Artery ◽  
Creatine Phosphokinase ◽  
Wedge Resection ◽  
Lower Lobe ◽  
Exploratory Laparotomy ◽  
Pathological Examination ◽  
Ischaemic Colitis ◽  
Intestinal Necrosis ◽  
General Thoracic Surgery ◽  
The Right

A 77-year-old man, who was taking prednisolone 7.5 mg, underwent wedge resection for nodules in the right lower lobe of the lung. The nodules were diagnosed as amyloid tumour. On the sixth postoperative day, sudden tachycardia, fever, creatine phosphokinase increase, renal dysfunction and metabolic acidosis were observed. CT showed no signs of infection, exacerbation of interstitial pneumonia, pulmonary embolism or occlusion in the major vessels of the mesentery. Exploratory laparotomy revealed intestinal necrosis in the inferior mesenteric artery area, and left hemicolectomy was performed. Postoperative pathological examination revealed gangrenous ischaemic colitis. Although gangrenous ischaemic colitis is not a complication specific to general thoracic surgery, it can be fatal. Because of the high risk of developing gangrenous ischaemic colitis in elderly patients and the increase in concomitant diseases, thoracic surgeons should always be mindful of the condition.

scholarly journals Tomographic findings in bronchial atresia

2021 ◽  
Vol 54 (1) ◽  
pp. 9-14
Author(s):  
Elazir Barbosa Mota Di Puglia ◽  
Rosana Souza Rodrigues ◽  
Pedro Augusto Daltro ◽  
Arthur Soares Souza Jr. ◽  
Marilene Monteiro Paschoal ◽  
...  
Keyword(s):  
Lower Lobe ◽  
Lung Parenchyma ◽  
Pulmonary Involvement ◽  
Middle Lobe ◽  
Pathological Examination ◽  
Surgical Specimen ◽  
Distal Lung ◽  
The Right ◽  
Ct Finding ◽  
Bronchial Atresia

Abstract Objective: To evaluate computed tomography (CT) findings in 23 patients with bronchial atresia. Materials and Methods: The CT images were reviewed by two radiologists who reached decisions by consensus. We included only patients who presented with abnormalities on CT and in whom the diagnosis had been confirmed by pathological examination of the surgical specimen (if the lesion was resected). The CT scans were assessed in order to identify the main findings and to map the distribution of the lesions (i.e., to determine whether the pulmonary involvement was unilateral or bilateral). Results: The main CT finding was the combination of bronchocele and hyperinflation of the distal lung. That combination was observed in all of the patients. The lesions were unilateral in all 23 cases, being seen predominantly in the left upper lobe, followed by the right lower lobe, right upper lobe, middle lobe, and left lower lobe. Conclusion: The diagnosis of bronchial atresia can be reliably made on the basis of a finding of bronchocele accompanied by hyperinflation of the adjacent lung parenchyma.

scholarly journals Peculiarities of radiological and laboratory values in patients with community-acquired pneumonia during COVID-19 pandemic

2021 ◽  
Vol 9 (4) ◽  
pp. 15-22
Author(s):  
V.I. Trykhlib ◽  
K.P. Bieliaieva ◽  
N.R. Tsyurak ◽  
L.O. Palatna
Keyword(s):  
Age Groups ◽  
Left Lung ◽  
Lower Lobe ◽  
Personal Data ◽  
Severe Form ◽  
Community Acquired Pneumonia ◽  
Lower Lung ◽  
The Right ◽  
Almost All ◽  
Frequent Localization

Literature and personal data on community-acquired pneumonia during the epidemic of a new coronavirus infection COVID-19 are presented. It was found that men and patients with moderately to severe form were treated for community-acquired pneumonia more often. The most common localizations were as follows (in descending frequency): bilateral multisegmental, right-sided lower lobe, left-sided lower lobe. Men as compared to women more often had the following localization of pneumonia: right-sided lower lobe pneumonia at the age of 20–30, 51–60; right-sided multisegmental in all age groups; left-sided lower lobe pneumonia at the age of 51–60, left-sided upper lobe pneumonia at the age of 20–50; left-sided multisegmental pneumonia in all age groups; slightly more frequent bilateral lower lobe pneumonia in different age groups; bilateral multisegmental pneumonia at the age of 20–30 and over 60. Conversely, the most common localization in women was as follows: right-sided lower lobe pneumonia at the age 31–50, right-sided upper lobe pneumonia at the age 20–30, left-sided lower lobe pneumonia at the age 20–50 and over 60, left-sided upper lobe pneumonia at the age over 60, bilateral lower lobe pneumonia at the age 31–40, bilateral multisegmental pneumonia at the age 41–60. Right-sided lower lobe pneumonia was equally often registered irrespective of gender in persons older than 60 years old. Right-sided upper lobe pneumonia was not registered in patients aged 31–40 and 41–50 years, and over 60 years old. The most frequent localization of pneumonia in mild form was left-sided lower lobe (35.3 %), right-si­ded lower lobe (20.6 %), and bilateral lower lobe (14.7 %). The least frequent were upper lobe localization of pneumonia in the right, left, and both lungs (2.94 % each), and left multisegmental pneumonia was not observed at all. The most frequent localization of pneumonia in the moderate form was the lower lobes of the right lung (29.4 %), left lung (18.3 %), and multisegmental in both lungs (28.8 %). It was least frequently registered in the upper lobe of the right lung (2.6 %), left lung (3.9 %) but was not registered in the upper lobes of both lungs. The most frequent localization of pneumonia in severe form was bilateral multisegmental (37.5 %). Right-sided multisegmental, left-sided lower lung and bilateral lower lung were the least common — 12.5 % for each. Subfebrile fever was registered more frequently in almost all localizations. More often normal or subfebrile temperature was registered in all localizations, except for right-sided upper lobe pneumonia, in which higher (febrile, pyretic) temperature was registered more often. In all localizations within three days after hospitalization most patients had normal leukocyte count, leukopenia was slightly more frequent in left-sided lower lobe pneumonia, leukocytosis — in the bilateral upper lobe, bilateral lower lobe, and right-sided upper lobe. In general, leukocytosis in community-acquired pneumonia was registered in 38.8 % of patients. In the first three days after hospitalization, a normal amount of lymphocytes was registered in the majority of patients, lymphopenia was observed in one-third of patients with right-sided upper and left-sided lower lobe localization.

scholarly journals Novel intronicDICER1variation associated with pleuropulmonary blastoma in two siblings

2019 ◽  
Vol 12 (1) ◽  
pp. e227391
Author(s):  
Bruce D Leckey ◽  
John M Carney ◽  
Jessica M Sun ◽  
Elizabeth N Pavlisko
Keyword(s):  
Lower Lobe ◽  
Large Mass ◽  
Pathological Examination ◽  
Pleuropulmonary Blastoma ◽  
Upper Respiratory Tract ◽  
Basal Segment ◽  
Lung Malignancies ◽  
History Of ◽  
Upper Respiratory ◽  
The Right

Pleuropulmonary blastomas (PPB) are rare aggressive paediatric lung malignancies associated withDICER1variants. We present two cases, a 2-year-old girl with upper respiratory tract symptoms as well as a 6-month-old girl sibling undergoing screening due to family history of malignancy. Imaging of the 2-year-old girl revealed a large mass filling the right hemithorax which was determined to be a type II PPB after pathological examination. Imaging of the 6-month-old sibling demonstrated a small cystic lesion in the posterior basal segment of the right lower lobe which was determined to be a type 1r PPB after pathological examination. The 2-year-old girl received adjuvant chemotherapy while the baby sister underwent resection alone and both are alive and well at 12 months and 7 months, respectively. Sequence analysis in both cases confirmed the sameDICER1variation, c.2437-2A>G (likely pathogenic), which has not been previously described in the literature.

Lower lobe origin is related to unfavorable outcomes in patients with stage I–III lung cancer treated with radical chemoradiotherapy

2020 ◽  
pp. 030089162097135
Author(s):  
Fangfang Liu ◽  
Xun Yuan ◽  
Jizong Jiang ◽  
Peng Zhang ◽  
Yuan Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lung Tumor ◽  
Survival Rates ◽  
Lower Lobe ◽  
Tumor Location ◽  
Stage I ◽  
Lung Lobe ◽  
Tumor Origin ◽  
Lower Lung ◽  
The Difference

Purpose: The influence of tumor location on survival was investigated in patients with lung cancer who received radical chemoradiotherapy. Methods: We examined the relationships between radiation site and survival outcome in patients with lung cancer. A total of 14,640 patients with lung cancer who received radical chemoradiotherapy for stage I–III disease were reviewed from Surveillance, Epidemiology, and End Results Program (SEER) datasets. We further retrospectively collected cases from a cohort of 148 eligible patients diagnosed between December 2013 and December 2019. Results: Female sex, adenocarcinoma, and stage III disease were significantly correlated with right lung lobe tumor. Advanced age at diagnosis was associated with lower lung tumor origin. For the patients who received radical chemoradiotherapy, 1- and 3-year survival rates were 56.5% and 22.9%. Lower lobe origin was closely related to a shorter overall survival compared to non-right lower lobe tumors ( p < 0.001). We also validated the difference in our cohort ( p = 0.004). Conclusions: Our results suggest that lower lobe tumor increases mortality risk in patients with lung cancer treated with radical chemoradiotherapy.

scholarly journals Giant congenital nodular melanoma in a newborn: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jun Zhou ◽  
Meng-xing Lv ◽  
Ling Duan ◽  
Yu-cheng Xie ◽  
Zhi-xiang A ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Surgical Resection ◽  
Doppler Ultrasound ◽  
Color Doppler ◽  
Surgical Excision ◽  
Color Doppler Ultrasound ◽  
In Utero ◽  
Braf V600e ◽  
Pathological Examination ◽  
The Right

Abstract Background Malignant melanoma (MM) arises predominantly after adolescence and is uncommon in children. Congenital MM in newborns is even rarer with a dearth of published literature; as a consequence, there is no uniform standard for the pathogenesis and treatment for neonatal malignant melanoma. Herein we report a case of giant congenital nodular MM in a newborn, including its clinical, imaging, pathological and molecular pathological features. This case is the largest giant congenital primary nodular malignant melanoma in utero in neonates currently reported in China. Case presentation A female neonatal patient was found to have a 2.97 cm× 1.82 cm×1.50 cm mass with a clear boundary at the right acromion in color Doppler ultrasound examination at 24 weeks of gestation. The mass increased to 3.0 cm×5.0 cm×9.0 cm at birth, and local ulceration was seen. MRI demonstrated that the mass was located on the right shoulder and underarm in a lobulated appearance, and surrounded the right scapula which was deformed. Clinical stage:IV(AJCC 8th Edition (2017)). α-Fetoprofein (AFP) by hematological examination: 1210ng/ml, NSE: 21.28ng/ml, LDH: 842U/L. The patient underwent surgical resection of the tumor, and was pathologically diagnosed as neonatal congenital malignant melanoma; immunohistochemistry (IHC): S-100 (+), HMB45 (+), Melan A (+), and Tyrosinase (+). Molecular pathological examination for BRAF V600E showed no mutations (Quantitative Real-time PCR, qPCR); And so were NRAS, C-kit (exons 9,11,13,14,17,18), and TERT (promoter locus, C228T and C250T) (Sanger sequencing). Non-surgical therapies were not carried out after the surgical resection of the tumor. After 6 months of follow-up, the child developed normally, and color Doppler ultrasound showed no obvious tumor growth or abnormality in the original tumor site. Conclusions It is extremely rare to see giant congenital primary nodular MM in utero in neonates. The pathogenesis, treatment and prognosis of congenital MM need further research. The diagnosis mainly depends on histopathology and immunohistochemistry, and it needs to be differentiated from malignant lymphoma and primitive neuroectodermal tumor. The current treatment strategy for MM relies on the surgical excision of the mass. Research directed at molecular detection for genetic mutations would contribute to targeted therapy and better prognosis.

scholarly journals Bilateral Choroidal Metastases as Presentation of Dissemination of Cutaneous Malignant Melanoma

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
S. Fernandez-Perez ◽  
O. Ruiz-Moreno ◽  
V. Pueyo ◽  
G. de la Mata ◽  
L. Pablo
Keyword(s):  
Malignant Melanoma ◽  
Cutaneous Melanoma ◽  
Posterior Pole ◽  
Cutaneous Malignant Melanoma ◽  
Pathological Examination ◽  
Blurred Vision ◽  
Pigmented Lesions ◽  
Multiple Metastases ◽  
Exhaustive Study ◽  
The Right

Case Report. A 47-year-old man presented with blurred vision in the right eye. Ophthalmoscopic examination showed several placoid, pigmented lesions in the posterior pole and midperiphery of the retina of both eyes.Results. Patient referred a cutaneous malignant melanoma on the back skin removed 6 years ago. A systemic workup revealed multiple metastases in liver and spleen. After an exhaustive study we concluded that it was a dissemination of a cutaneous malignant melanoma with bilateral choroidal metastases, liver and spleen metastases. The patient obtained clinical ocular improvement after palliative chemotherapy, although he died in the following months. Pathological examination of the lesions confirmed the diagnosis of choroidal metastases from a malignant cutaneous melanoma.Conclusions. Monitoring patients who have had cutaneous malignant melanoma is very important, since melanoma metastases may occur even many years after the diagnosis of the primary tumor. Choroidal metastases from cutaneous melanoma are uncommon but we should be aware because their appearance worsens prognosis.

Ultrasound-guided Thoracoscopic Dental Extraction

2013 ◽  
Vol 79 (9) ◽  
pp. 891-892 ◽  
Author(s):  
Samir R. Pandya ◽  
Rodrigo Ruiz ◽  
Adele Brudnicki
Keyword(s):  
Foreign Body ◽  
Wedge Resection ◽  
Intraoperative Ultrasound ◽  
Lower Lobe ◽  
Flexible Bronchoscopy ◽  
Neurologically Impaired ◽  
Impaired Child ◽  
Segmental Bronchus ◽  
Distal Location ◽  
The Right

Recurrent pneumonias in children may be from an unrecognized aspirated foreign body. Our patient was a 10-year-old neurologically impaired child with an aspirated tooth in the right lower lobe segmental bronchus that was inaccessible to extraction using flexible bronchoscopy because of its extremely distal location. We used intraoperative ultrasound during thoracoscopy to locate the foreign body, a tooth, and to facilitate a wedge resection of the involved lung. This combined approach with ultrasound and thoracoscopy can be useful in managing an aspirated foreign body that cannot be extracted from the airway using conventional rigid or flexible bronchoscopy.

scholarly journals Burkholderia cepacia: An unusual cause of pneumonia

2021 ◽  
Vol 6 (4) ◽  
pp. 249-252
Author(s):  
Arjun A S ◽  
Prasanna Kumar T ◽  
Manjunath H K
Keyword(s):  
Burkholderia Cepacia ◽  
Lower Lobe ◽  
Lung Abscess ◽  
High Grade Fever ◽  
Home Setting ◽  
Prescription Practices ◽  
Male Farmer ◽  
History Of ◽  
Chest X Ray ◽  
The Right

Burkholderia Cepacia is a gram negative organism, an uncommon cause of pneumonia. When isolated, it usually represents colonisation. In the presence of immunocompromising conditions, it can cause disease, ranging from mild illness to the highly fatal Cepacia syndrome. The organism is intrinsically resistant to many antibiotics. We report a 57 years old male farmer, who has diabetes mellitus and bronchial asthma, who presented with a acute history of high grade fever, pain abdomen and cough. He was diagnosed with a ruptured liver abscess, with the infection spreading to the right lower lobe. Laparotomy was performed. Pus culture grew Pseudomonas aeruginosa. He improved upon antibiotic therapy, only to return after one month with severe cough, chest X-ray revealing a lung abscess in the right lower lobe. Bronchoalveolar lavage culture grew Burkholderia cepacia, and sensitive antibiotics were initiated, however the patient succumbed to the illness. The implicated source of the organism was the nebulisation solution which he was using regularly. Emphasis should be laid on the need for improved aseptic practices while using medical solutions at either hospital or home setting. An index of suspicion may guide optimal antibiotic prescription practices in susceptible individuals.

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