scholarly journals Pericardial synovial sarcoma presenting with unstable angina

2019 ◽  
Vol 28 (1) ◽  
pp. 59-61
Author(s):  
Kirsten Y Wong ◽  
Eric Hong ◽  
Chee-Meng Fong ◽  
Poo-Sing Wong
Keyword(s):  
Unstable Angina ◽  
Synovial Sarcoma ◽  
Mediastinal Mass ◽  
Incidental Finding ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Anterior Mediastinal Mass ◽  
Artery Bypass Graft ◽  
Circumflex Artery ◽  
External Compression

A 43-year-old man had an incidental finding of a large anterior mediastinal mass. He suddenly presented with unstable angina and an emergency coronary angiogram showed severe proximal circumflex artery and left anterior descending artery stenosis from external compression. He underwent emergency coronary artery bypass graft surgery and excision of the tumor. At surgery, the tumor was found to be invading the left ventricle, so debulking of the mediastinal tumor was performed. Histology showed a biphasic pericardial synovial sarcoma. The patient was recommended chemotherapy and radiotherapy but he refused. He died 13 months after surgery.

scholarly journals Histopathological analysis of the coronary atheroma extracted during coronary artery bypass graft surgery

2018 ◽  
Vol 11 (3) ◽  
pp. 226
Author(s):  
Redoy Ranjan ◽  
Dipannita Adhikary ◽  
Mayank Acharya ◽  
Saumitra Chakravarty ◽  
Sanjoy Kumar Saha ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Coronary Artery ◽  
Smooth Muscle Cell ◽  
Unstable Angina ◽  
Muscle Cell ◽  
Foam Cell ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Histopathological Analysis ◽  
Artery Bypass Graft

<p class="Abstract">This study aims to evaluate the histopathological analysis as well as the effect of coronary endarterectomy with severe calcified coronary artery disease. During the year of 2015 to 2017, a total of 135 patients (56 patients of stable angina and 79 patients of unstable angina) underwent atherectomy in adjunct to off-pump coronary artery bypass graft surgery. Histopathological study of atheroma specimen demonstrates the presence of calcification, foam cell, cholesterol clefts, thrombus, smooth muscle cell, and also necrotic tissue using standard hematoxylin and eosin stain techniques. However, smooth muscle cells and foam cell were identified with plaque using the monoclonal antibodies. Thrombus was more common in unstable angina group of patients (64.4%) in comparison to the patients with stable angina (23.2%). An accelerated progression pattern of smooth muscle cell proliferation and calcification were observed which was also common and significantly higher in unstable angina group of patients. The presence of thrombus and accelerated progressive pattern of smooth muscle cell proliferation in unstable angina patients imply the episodic disruption of atheromatous plaque followed by subsequent healing and may play a vital role in the pathophysiology of underlying angina pectoris.</p>

scholarly journals Aprotinin Decreases Postoperative Bleeding and Number of Transfusions in Patients on Clopidogrel Undergoing Coronary Artery Bypass Graft Surgery

Circulation ◽  
2005 ◽  
Vol 112 (9_supplement) ◽  
Author(s):  
Jan van der Linden ◽  
Gabriella Lindvall ◽  
Ulrik Sartipy
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Unstable Angina ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Postoperative Bleeding ◽  
Artery Bypass Graft ◽  
Perioperative Bleeding ◽  
The Impact

Background— Clopidogrel, an irreversible platelet inhibitor, is used to treat patients with unstable angina. These patients often present for coronary artery bypass graft surgery (CABG) and are at increased risk for perioperative bleeding. The current investigation evaluates the impact of aprotinin on bleeding and transfusion requirements in clopidogrel-treated patients undergoing CABG. Methods and Results— Seventy-five consecutive patients with unstable angina, administered clopidogrel <5 days before CABG, were randomized. Using a double-blind design, patients received full-dose aprotinin (n =37) or saline (n =38). Elapsed times between the last dose of clopidogrel and start of the operation were similar between the 2 groups [aprotinin, 58±28 hour (mean± SD); control, 54±27 hour; P =0.86], as were age (aprotinin, 66.4±10 years; control, 68.3±10 years; P =0.51), number of distal anastomoses (aprotinin, 3.6±1.0; control, 3.7±1.0; P =0.79), operative times (aprotinin, 192±48 minutes; control, 200±53 minutes; P =0.55), and lowest intraoperative hemoglobin level (aprotinin, 87±14 g/L; control, 88±14 g/L; P =0.60). Postoperative bleeding was 760±350 mL in aprotinin-treated patients versus 1200±570 mL ( P <0.001) in control. During the hospital stay, patients in the aprotinin group received 1.2±1.5 and 0.1±0.4 U of erythrocytes and platelets, respectively, versus 2.8±3.2 ( P =0.02) and 0.9±1.4 ( P =0.002) units in the control. In the aprotinin group, 53% of patients received transfusions, whereas 79% of controls were exposed to blood products ( P =0.02). Conclusions— Intraoperative aprotinin decreases postoperative bleeding and the number of transfusions in patients undergoing CABG and treated with clopidogrel <5 days before surgery.

scholarly journals Unstable angina does not increase mortality in coronary artery bypass graft surgery

2013 ◽  
Vol 28 (3) ◽  
pp. 391-400
Author(s):  
Carolina Pelzer Sussenbach ◽  
João Carlos Guaragna ◽  
Rômulo Soares Castagnino ◽  
Jaqueline Piccoli ◽  
Luciano Cabral Albuquerque ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Unstable Angina ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Artery Bypass Graft
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