Does cannabis use modify the effect of post-traumatic stress disorder on severe depression and suicidal ideation? Evidence from a population-based cross-sectional study of Canadians

2019 ◽  
Vol 34 (2) ◽  
pp. 181-188
Author(s):  
Stephanie Lake ◽  
Thomas Kerr ◽  
Jane Buxton ◽  
Zach Walsh ◽  
Brandon DL Marshall ◽  
...  

Background: Post-traumatic stress disorder sharply increases the risk of depression and suicide. Individuals living with post-traumatic stress disorder frequently use cannabis to treat associated symptoms. We sought to investigate whether cannabis use modifies the association between post-traumatic stress disorder and experiencing a major depressive episode or suicidal ideation. Methods: We used data from the 2012 Canadian Community Health Survey-Mental Health, a nationally representative cross-sectional survey of non-institutionalized Canadians aged ⩾15 years. The relationship between post-traumatic stress disorder and each outcome was modelled using logistic regression with an interaction term for cannabis and post-traumatic stress disorder, controlling for demographic characteristics, mental health, and substance use comorbidities. The ratio of odds ratios and relative excess risk due to interaction was calculated to measure interaction on the multiplicative and additive scales, respectively. Results: Among 24,089 eligible respondents, 420 (1.7%) reported a current clinical diagnosis of post-traumatic stress disorder. In total, 106 (28.2%) people with post-traumatic stress disorder reported past-year cannabis use, compared to 11.2% of those without post-traumatic stress disorder ( p < 0.001). In multivariable analyses, post-traumatic stress disorder was significantly associated with recent major depressive episode (adjusted odds ratio = 7.18, 95% confidence interval: 4.32–11.91) and suicidal ideation (adjusted odds ratio = 4.76, 95% confidence interval: 2.39–9.47) among cannabis non-users. post-traumatic stress disorder was not associated with either outcome among cannabis-using respondents (both p > 0.05). Conclusions: This study provides preliminary epidemiological evidence that cannabis use may contribute to reducing the association between post-traumatic stress disorder and severe depressive and suicidal states. There is an emerging need for high-quality experimental investigation of the efficacy of cannabis/cannabinoids for the treatment of post-traumatic stress disorder.

2019 ◽  
Vol 41 (4) ◽  
pp. 369-374
Author(s):  
Adriana Raquel Binsfeld Hess ◽  
Rosa Maria Martins de Almeida

Abstract Objective To explore and describe sociodemographic characteristics, crack consumption patterns, and psychiatric comorbidities of female crack users receiving treatment at therapeutic communities. Methods This was a cross-sectional, descriptive, quantitative study. Forty-six women who abstained from crack use were assessed using a sociodemographic questionnaire, the Mini-Mental State Examination (MMSE), the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), and a profile of crack use questionnaire. Descriptive statistical analyses were conducted. Results Participants had a mean age of 31.02 years (standard deviation [SD] = 7.73), most were single (76.1%), white (67.4%) and had complete or incomplete elementary education (43.5%). Before treatment, 65.2% of the women reported using crack every day; 46.3% smoked between 10 to 30 crack rocks per week. Mean treatment time was 63.56 days (SD = 75.85), with a mean of 80.41 days of abstinence (SD = 74.52) and 3.37 previous treatments (SD = 5.49). Mean age upon crack use initiation was 22.61 years (SD = 8.06), and the most frequent motivation to start using crack was curiosity (78.3%). The mean lifetime duration of crack use was 82.26 months (SD = 74.76), and the physical complications most frequently reported were weight loss (93.5%), followed by sleep problems (87%). In this study, the most prevalent psychiatric diagnoses were major depressive episode (60.87%), followed by post-traumatic stress disorder (52.17%) and generalized anxiety disorder (13.07%). Conclusions Overall, a pattern of high consumption of crack was observed. The results show a high frequency of mood and anxiety disorders, with the highest frequencies found for major depressive episode and post-traumatic stress disorder.


Author(s):  
Hariri El Mehdi ◽  
Sellouti Mohamed ◽  
Nguadi Jaouad ◽  
Chhoul Hakima

Introduction : Odontophobia is a complex anxiety disorder related to excessive fear of dental care. Of multifactorial origin, it affects more females than males at all ages. Odontophobia can also be associated with other disorders, namely post-traumatic stress disorder (PTSD), which is recognized in refugees from civil wars. Materials and methods : Descriptive and analytical cross-sectional epidemiological study, carried out during February 2020 at the Syrian refugee camp in Zaatari, Jordan, involving 200 consultants at the dental office to assess their degree of odontophobia and to determine the risk factors associated with this disorder, particularly post-traumatic stress disorder (PTSD). Results : The authors collated 200 subjects of which 125 (62.5%) were phobic with a corah score (> or = to 13) and 75 (37.5%) were non-phobic with a corah score (< to 13). The sex ratio was statistically different between the two populations with a predominance of female sex (p=0.025). odontophobia is also related to the length of time spent in Syria during the civil war, it is observed more in 96 (48%) patients who spent between (13 and 24 months) (p=0.017). Similarly, odontophobia is influenced by post-traumatic stress disorder in its severe form (p=0.011). Conclusion: Descriptive and analytical observational epidemiological study showing the high prevalence of odontophobia among Syrian refugees consulting at the dental office of the Moroccan military medical-surgical hospital in Zaatari camp in Jordan and its influence by post-traumatic stress disorder (PTSD).


Author(s):  
Khalid Astitene ◽  
Hassan Aguenaou ◽  
Laila Lahlou ◽  
Amina Barkat

Aim: After a traumatic event, the person can develop post-traumatic stress disorder (PTSD), the purpose of the study is to assess the prevalence of PTSD in adolescents in public middle schools of the prefecture of Salé in Morocco and study anxiety and depression which are the comorbid disorders of the PTSD. The survey was carried out from March to June 2017. Methods: 523 students were selected by the cross-sectional method from fifteen schools that were randomly selected, the age of the students vary between 12 and 17 years. For the survey, standardized questionnaires (the socio-demographic data, the Life Events Checklist, the CPTS-RI (Children's Post Traumatic Stress Reaction Index), the STAIY (State Trait Inventory Anxiety Form Y) and the CDI (Children Depression Inventory) were used which were filled in by the students. Results: The prevalence of PTSD was 70.4% in the students who have PTSD. We found that the prevalence in boys was 46.74%, while in girls it was 53.26%. In addition to that, 81% of students found to be anxious and 51.8% of students have depression. Conclusion: There is a high prevalence of post traumatic stress disorder among adolescents, there are practical implications for the support and care of these adolescents.


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