Prognostic Radiographic Aspects of Spondylolisthesis

1984 ◽  
Vol 25 (5) ◽  
pp. 427-432 ◽  
Author(s):  
H. Saraste ◽  
L.-Å. Broström ◽  
T. Aparisi
Keyword(s):  
Lumbar Spine ◽  
Prognostic Value ◽  
Radiographic Examination ◽  
Initial Examination ◽  
Lumbar Spondylolysis ◽  
Lumbosacral Lordosis ◽  
Disk Height ◽  
Flexion And Extension ◽  
Observation Period

A series of 202 patients (133 men, 69 women) with lumbar spondylolysis were examined radiographically on two occasions, first at the time of diagnosis and later at a follow-up, after an observation period of 20 years or more. The films from patients in groups without and with moderate and severe olisthesis were evaluated with respect to variables describing lumbosacral lordosis, wedging of the spondylolytic vertebra, lengths of the transverse processes and iliolumbar ligaments, disk height, progression of slipping, and influence on measured olisthesis of lumbar spine flexion and extension at the radiographic examination. The evaluation was made with special attention to possible signs which could be predictive for the prognosis of vertebral slipping. Progession of slipping did not differ between patients diagnosed as adults or adolescents. Reduction of disk height was correlated to the degree of slipping present at the initial examination and to the progression of olisthesis. Flexion and extension of the lumbar spine did not modify the degree of olisthesis. Data concerning the lengths of the transverse processes and the iliolumbar ligaments, and lumbar lordosis, cannot be used for prognostic purposes. The lumbar index reflecting the degree of wedge deformity of the spondylolytic vertebra was shown to be the only variable of prognostic value for the development of vertebral slipping.

Long-term follow-up in patients with autonomous thyroid adenoma

1993 ◽  
Vol 128 (1) ◽  
pp. 51-55 ◽  
Author(s):  
D Sandrock ◽  
T Olbricht ◽  
D Emrich ◽  
G Benker ◽  
D Reinwein
Keyword(s):  
Prognostic Value ◽  
Definitive Treatment ◽  
Thyroid Adenoma ◽  
Trh Test ◽  
Long Term Follow Up ◽  
Autonomous Adenoma ◽  
Observation Period ◽  
Treatment Surgery

A group of 375 untreated euthyroid patients with solitary autonomous adenoma of the thyroid were studied in a long-term follow-up (observation period 52.8 (mean)/46 (median), range 3–204 months). During the period of observation, 133 (34.2%) of all initially untreated patients underwent treatment (surgery, radioiodine, antithyroid medication) because of hyperthyroidism, mechanical problems, or at the patient's request. Sixty-seven patients developed hyperthyroidism resulting in a mean incidence of 4.1% per year. The incidence of hyperthyroidism increased during follow-up (3% in the first seven years, 10% in the following years). Age, sex, nodule size, initial scintigraphic appearance and the TRH test were of no individual prognostic value in predicting hyperthyroidism. Eleven of 14 patients with untreated hyperthyroidism became euthyroid without treatment during the time of follow-up. After iodine excess (by history or elevated iodine levels in urine, N=45), 14 patients (31%) developed hyperthyroidism. In conclusion, we recommend a definitive treatment of autonomous adenoma at least in patients with advanced age, concomitant diseases and a higher probability of iodine exposure.

Facet Joint Replacement: Intermediate- and Long-Term Outcome in a Large Case Series

2020 ◽  
Vol 82 (01) ◽  
pp. 034-042
Author(s):  
Ulrich J. Knappe ◽  
David Reinecke ◽  
Michael Flörke ◽  
Peter Horn ◽  
Robert Schönmayr
Keyword(s):  
Lumbar Spine ◽  
Joint Replacement ◽  
Facet Joint ◽  
Case Series ◽  
Leg Pain ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Disk Height

Abstract Background The long-term outcome of facet joint replacement (FJR) still is to be proven. Methods We present a prospective case series of 26 (male-to-female ratio of 1:1; mean age: 61 years) patients undergoing FJR with a follow-up of at least 1 year (range: 12–112; mean: 67 months). Visual analog scale (VAS) for back and leg pain, Oswestry Disability Index (ODI), and the 12-Item Short Form Health Survey (SF-12) were applied pre- and postoperatively (after 3, 6, and 12 months) as well as at the last follow-up (N = 24). Using X-rays of the lumbar spine (N = 20), the range of motion (ROM) and disk height in the indicator and adjacent levels were assessed. Results FJR was performed at L3/L4 (N = 7), L4/L5 (N = 17), and L5/S1 (N = 2). Mean VAS (mm) for back pain decreased from 71 to 18, mean VAS for right leg pain from 61 to 7, and from 51 to 3 for the left leg. Mean ODI dropped from 51 to 22% (for all p < 0.01). Eighty seven percent of patients were satisfied and pretreatment activities were completely regained in 78.3% of patients. Disk height at the indicator and adjacent levels and ROM at the indicator segment and the entire lumbar spine were preserved. No loosening of implants was observed. Explantation of FJR and subsequent fusion had to be performed in four cases (15.4%). Conclusions In selected cases, long-term results of FJR show good outcome concerning pain, quality of life, preservation of lumbar spine motion, and protection of adjacent level.

scholarly journals In vivo studies on flexion and extension of the lumbar spine after stabilisation with a non-fusion pedicle screw system

2012 ◽  
Vol 11 (3) ◽  
pp. 195-199
Author(s):  
Jörg Rainer Klauß ◽  
MJ Richter ◽  
Hendrik Bergert ◽  
Rainer Braunschweig ◽  
Klaus Roehl
Keyword(s):  
Lumbar Spine ◽  
Surgical Intervention ◽  
Life Assessment ◽  
Computer Assisted ◽  
Lateral Projection ◽  
Flexion Extension ◽  
Micro Motion ◽  
Flexion And Extension

OBJECTIVE: The aim was to determine in vivo whether pre-operative mobility of the lumbar spine (overall and segmental) is retained after surgical intervention. METHODS: Functional imaging of the lumbar spine was performed in flexion and extension, using a lateral projection under standardised conditions. This allowed assessment of the overall mobility, mobility of the instrumented mobile segments and the disc height of the adjacent cranial segment (intervertebral space; IVS) before and after surgical intervention. Images were evaluated independently by a radiologist and an orthopaedic surgeon. A comparative analysis of preoperative and postoperative functional images was carried out with the aid of a computer and appropriate software (ACES) for further assessment of the extent to which the range of movement was retained. The Oswestry Disability Index (ODI, quality of life assessment) and the visual analogue scale (VAS, pain assessment) were used as clinical criteria and compared pre-and postoperatively. The mean follow-up (FU) intervals were 13.5 days (FU 1) and 19 months (FU 2). RESULTS: Radiological results showed that the overall mobility of the lumbar spine (L1 to S1) decreased on average by one third of the flexion/extension range, from 25.0º preoperatively to 17.6º postoperatively. The segmental mobility of the monosegmental stabilisation decreased on average from 3.7º to 2.3º. The caudal segments of the bisegmental dynamic stabilisation retained their preoperative movement range of 2.6º, with a postoperative range of 2.4º. The IVS did not change. The ODI improved postoperatively from 59 (preoperative) to 39/41 (FU1/FU2) points, while the VAS (during movement) improved from 7.6 (pre-op) to 4.4/4.5 (FU1/FU2). Computer-assisted analysis showed that small and functionally insignificant micro-motion of 0.4º (error 0.12%) remained in the stabilised and unfused mobile segment. CONCLUSION: Comparison of preoperative and postoperative measurements showed that overall mobility and segmental micro-motion were retained after non-fusion stabilisation of the lumbar spine with monosegmental and bisegmental instrumentation. The adjacent cranial segment (IVS) did not collapse. Activity levels (ODI) and pain symptoms (VAS) of the patients showed significant improvement at follow-up, comparable to that reported in the literature for conventional rigid spinal fusions.

1089: Prognostic Value of Molecular Staging of Bladder Cancer with RT -PCR Assay for KRT20: Results at 5 Year-Follow-up

2007 ◽  
Vol 177 (4S) ◽  
pp. 360-360
Author(s):  
Ana Agud ◽  
Maria J. Ribal ◽  
Lourdes Mengual ◽  
Mercedes Marin-Aguilera ◽  
Laura Izquierdo ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Prognostic Value ◽  
Rt Pcr ◽  
Pcr Assay ◽  
Molecular Staging

733: The Prognostic Value of E-Cadherin, Alpha-, and Beta-Catenin in Invasive Bladder Cancer Patients: Long Term Follow-Up Study

2004 ◽  
Vol 171 (4S) ◽  
pp. 194-195
Author(s):  
Kyoichi Tomita ◽  
Haruki Kume ◽  
Keishi Kashibuchi ◽  
Satoru Muto ◽  
Shigeo Horie ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Patients ◽  
Prognostic Value ◽  
Invasive Bladder Cancer ◽  
Beta Catenin ◽  
Follow Up Study ◽  
Long Term Follow Up ◽  
E Cadherin

HRA Model for Hypercholesterolemia Based on a Longitudinal Health Database

1998 ◽  
Vol 37 (02) ◽  
pp. 130-133
Author(s):  
T. Kishimoto ◽  
Y. Iida ◽  
K. Yoshida ◽  
M. Miyakawa ◽  
H. Sugimori ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Proportional Hazards ◽  
Proportional Hazards Model ◽  
Model Analysis ◽  
Serum Total Cholesterol ◽  
Hazards Model ◽  
The Mean ◽  
Health Database ◽  
Observation Period

AbstractTo evaluate the risk factors for hypercholesterolemia, we examined 4,371 subjects (3,207 males and 1,164 females) who received medical checkups more than twice at an AMHTS in Tokyo during the period from 1976 through 1991; and whose serum total cholesterol was under 250 mg/dl. The mean follow-up duration was 6.6 years. A self-registering questionnaire was administered at the time of the health checkup. The endpoint of this study was the onset of hypercholesterolemia when the level of serum total cholesterol was 250 mg/dl and over. We compared two prognosis groups (normal and hypercholesterol) in terms of age, examination findings and lifestyle. After assessing each variable, we employed Cox's proportional hazards model analysis to determine the factors related to the occurrence of hypercholesterolemia. According to proportional hazards model analysis, total cholesterol, triglyceride and smoking at the beginning, and hypertension during the observation period were selected in males; and total cholesterol at the beginning and age were selected in females to determine the factors related to the occurrence of hypercholesterolemia.

Nonsurgical Endodontik Retreatment of Maxillary First Premolar

DENTA ◽  
2017 ◽  
Vol 11 (1) ◽  
pp. 88
Author(s):  
Yongki Hadinata W ◽  
Karlina Samadi
Keyword(s):  
Root Canal ◽  
Radiographic Examination ◽  
Periapical Lesion ◽  
First Choice ◽  
Periapical Abscess ◽  
Dental Hospital ◽  
Conservative Dentistry ◽  
Previously Treated ◽  
Endodontic Retreatment

<p><strong><em>Background :</em></strong><em> There are some factors can cause endodontic failure such as inadequate in cleaning or shaping step, non hermetic obturation, or poor restoration, which can cause bacteria multiply. <strong>Purpose :</strong> To report the management of endodontic failure with nonsurgical treatment. <strong>Case :</strong> 46-year-old woman came to Airlangga Dental Hospital Conservative Dentistry Department to treat her upper right tooth which show symptomatic pain in the last 2 weeks. The tooth has been treated and crowned with porcelain fused to metal about 10 years ago. Clinical examination show the presence of fistula on premolar buccal gingiva, react to percussion.  Radiographic examination show not hermetic obturation in one root canal and radiolucency in the periapical area. The diagnosis for maxillary first premolar is previously treated tooth with chronic periapical abscess.. <strong>Treatment :</strong> Crown and post was removed from the tooth, and endodontic retreatment was done. Follow up 6 months after the retreatment show no reaction to percussion, and radiographic examination show no enlargement periapical lesion. <strong>Conclusion :</strong> Nonsurgical endodontic retreatment always become the first choice to resolve endodontic failure for previously treated tooth.</em></p><p><strong><em>Keywords :</em></strong><em> endodontic failure, maxillary first premolar, nonsurgical endodontic retreatment</em></p><p><strong><em>Correspondence:</em></strong><em> Yongki Hadinata W., drg. PPDGS Ilmu Konservasi Gigi Fakultas Kedokteran Gigi Universitas Airlangga, Surabaya. Jl. Mayjen. Prof. Dr. Moestopo No. 47, Surabaya.</em></p>

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